Ser-Ap-Es

Hypertensive disease

Treatment

1 FDA approval

20 Active Studies for Ser-Ap-Es

Treatment for

Hypertensive disease

What is Ser-Ap-Es

ReserpineThe Generic name of this drug

Treatment SummaryHydrochlorothiazide is a medication used to treat swelling and high blood pressure. It is the most commonly prescribed thiazide diuretic, but its use is declining in favor of drugs such as angiotensin converting enzyme inhibitors and angiotensin II receptor blockers. It was approved by the FDA in 1959 and is available in combination with other drugs.

Ser-Ap-Esis the brand name

image of different drug pills on a surface

Ser-Ap-Es Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Ser-Ap-Es

Reserpine

1960

Approved as Treatment by the FDA

Reserpine, also called Ser-Ap-Es, is approved by the FDA for 1 uses like Hypertensive disease .

Hypertensive disease

Used to treat High Blood Pressure (Hypertension) in combination with Polythiazide

Effectiveness

How Ser-Ap-Es Affects PatientsHydrochlorothiazide helps the body get rid of more water through urine. The amount of hydrochlorothiazide taken will vary from person to person, but is usually between 25-100mg. People with weakened kidney or liver function should be especially careful when taking this drug.

How Ser-Ap-Es works in the bodyHydrochlorothiazide works by preventing the reabsorption of sodium and chloride, which causes water to be excreted from the body. This drug is transported from the blood into the cells lining the distal convoluted tubule in the kidneys, and then sent to the lumen of the tubule. Normally, sodium is reabsorbed into these cells and then pumped out into the bloodstream, causing a concentration gradient that encourages water to be reabsorbed. However, by blocking this reabsorption process, hydrochlorothiazide decreases the concentration gradient and reduces the amount of water that is reabsorbed by the body.

When to interrupt dosage

The suggested dosage of Ser-Ap-Es is contingent upon the identified condition, like Antepartum magnesium sulfate prevention, inadequately regulated blood pressure with single treatment and antihypertensives. The measure of dosage fluctuates in accordance with the technique of administration (e.g. Tablet, coated - Oral or Oral) recorded in the table beneath.

Condition

Dosage

Administration

Hypertensive disease

, 0.1 mg, 0.25 mg, 0.125 mg, 25.0 mg

, Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral

Warnings

There are 20 known major drug interactions with Ser-Ap-Es.

Common Ser-Ap-Es Drug Interactions

Drug Name

Risk Level

Description

Abemaciclib

Major

The serum concentration of Abemaciclib can be increased when it is combined with Reserpine.

Amifostine

Major

Reserpine may increase the hypotensive activities of Amifostine.

Amisulpride

Major

Reserpine may increase the antipsychotic activities of Amisulpride.

Astemizole

Major

The metabolism of Astemizole can be increased when combined with Reserpine.

Axitinib

Major

The serum concentration of Axitinib can be increased when it is combined with Reserpine.

Ser-Ap-Es Toxicity & Overdose RiskThe lowest toxic dose of hydrochlorothiazide in mice and rats has been found to be greater than 10g/kg. Those who overdose on the drug may experience low levels of potassium, chloride, and sodium in the blood. To treat these symptoms, supportive care including fluids and electrolytes is recommended, as well as vasopressors to treat hypotension and oxygen for respiratory impairment.

image of a doctor in a lab doing drug, clinical research

Ser-Ap-Es Novel Uses: Which Conditions Have a Clinical Trial Featuring Ser-Ap-Es?

158 active clinical trials are currently examining the potential of Ser-Ap-Es in providing relief from Cirrhosis, Edema and Congestive Heart Failure.

Condition

Clinical Trials

Trial Phases

Hypertensive disease

23 Actively Recruiting

Not Applicable, Phase 1, Phase 2, Phase 3

Ser-Ap-Es Reviews: What are patients saying about Ser-Ap-Es?

5Patient Review

1/29/2019

Ser-Ap-Es for High Blood Pressure

This drug has been the most effective in lowering my blood pressure to a normal level. I have tried many different drugs, but none of them have been as successful as this one.

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about ser-ap-es

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Clinical Trials for Ser-Ap-Es

Have you considered Ser-Ap-Es clinical trials? We made a collection of clinical trials featuring Ser-Ap-Es, we think they might fit your search criteria.

Have you considered Ser-Ap-Es clinical trials? We made a collection of clinical trials featuring Ser-Ap-Es, we think they might fit your search criteria.