Terazosin Hydrochloride

Enlarged Prostate, Hypertensive disease, Ureteral Calculi
Treatment
2 FDA approvals
20 Active Studies for Terazosin Hydrochloride

What is Terazosin Hydrochloride

TerazosinThe Generic name of this drug
Treatment SummaryTerazosin is a medication used to treat benign prostatic hyperplasia and high blood pressure. It works by blocking the action of adrenaline on the alpha-1 adrenergic receptors, which helps relax the muscles in the blood vessels and prostate.
Hytrinis the brand name
image of different drug pills on a surface
Terazosin Hydrochloride Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Hytrin
Terazosin
1987
173

Approved as Treatment by the FDA

Terazosin, otherwise known as Hytrin, is approved by the FDA for 2 uses including Hypertensive disease and Enlarged Prostate .
Hypertensive disease
Helps manage High Blood Pressure (Hypertension)
Enlarged Prostate

Effectiveness

How Terazosin Hydrochloride Affects PatientsTerazosin is a type of drug that helps block the actions of certain hormones in the body (alpha-1 adrenergic hormones) to help treat certain conditions.
How Terazosin Hydrochloride works in the bodyTerazosin targets certain receptors found in the blood vessels and prostate. When those receptors are blocked, the smooth muscles in those areas relax, reducing blood pressure and improving urine flow. Terazosin has also been shown to stop cell growth and cause some prostate cells to die, a process called apoptosis. This is done by increasing the expression of certain factors like TGF-beta1, p27kip1, and caspase.

When to interrupt dosage

The proposed dosage of Terazosin Hydrochloride is contingent upon the ascertained condition, for example Ureteral Calculus, Hypertensive disease and Enlarged Prostate. The measure of dosage relies upon the technique of administration (e.g. Capsule, liquid filled or Capsule - Oral) as indicated in the table below.
Condition
Dosage
Administration
Enlarged Prostate
10.0 mg, , 1.0 mg, 2.0 mg, 5.0 mg
, Oral, Capsule, Capsule - Oral, Tablet - Oral, Tablet, Kit; Tablet, Kit; Tablet - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral
Hypertensive disease
10.0 mg, , 1.0 mg, 2.0 mg, 5.0 mg
, Oral, Capsule, Capsule - Oral, Tablet - Oral, Tablet, Kit; Tablet, Kit; Tablet - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral
Ureteral Calculi
10.0 mg, , 1.0 mg, 2.0 mg, 5.0 mg
, Oral, Capsule, Capsule - Oral, Tablet - Oral, Tablet, Kit; Tablet, Kit; Tablet - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral

Warnings

Terazosin Hydrochloride Contraindications
Condition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Terazosin may interact with Pulse Frequency
There are 20 known major drug interactions with Terazosin Hydrochloride.
Common Terazosin Hydrochloride Drug Interactions
Drug Name
Risk Level
Description
Acepromazine
Major
Terazosin may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Acepromazine.
Alfuzosin
Major
Terazosin may increase the hypotensive activities of Alfuzosin.
Amifostine
Major
Terazosin may increase the hypotensive activities of Amifostine.
Aripiprazole
Major
Terazosin may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Aripiprazole.
Aripiprazole lauroxil
Major
Terazosin may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Aripiprazole lauroxil.
Terazosin Hydrochloride Toxicity & Overdose RiskIf someone takes too much terazosin, they may have low blood pressure. To help control their heart rate and blood pressure, they should lie down and may need extra fluids or medicine to increase their blood pressure. It is important to monitor their kidney function. Since terazosin is strongly bound to proteins, dialysis is not likely to be very effective in removing the drug from the body. The lowest toxic dose of terazosin in mice is 5500mg/kg.
image of a doctor in a lab doing drug, clinical research

Terazosin Hydrochloride Novel Uses: Which Conditions Have a Clinical Trial Featuring Terazosin Hydrochloride?

39 active clinical trials are currently being conducted to assess the potential of Terazosin Hydrochloride to treat Enlarged Prostate, Ureteral Calculus and Hypertensive Disease.
Condition
Clinical Trials
Trial Phases
Hypertensive disease
23 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3
Enlarged Prostate
21 Actively Recruiting
Not Applicable, Phase 4, Phase 2
Ureteral Calculi
0 Actively Recruiting

Terazosin Hydrochloride Reviews: What are patients saying about Terazosin Hydrochloride?

5Patient Review
8/8/2016
Terazosin Hydrochloride for Enlarged Prostate with Urination Problems
I experienced really great results while taking this medication for a year. However, I recently had to stop because it started causing an irregular heartbeat. Thankfully, my heart is back to normal now.
5Patient Review
4/28/2019
Terazosin Hydrochloride for Enlarged Prostate with Urination Problems
I began with a low dose of 1mg, and have since increased to 5mg in the morning and 5mg at night. I haven't experienced any negative side effects, save for feeling lightheaded if I stand up too quickly. The medication has been effective in controlling my urination symptoms, which is something I'm grateful for. Although I would prefer not to be taking medication at all, this treatment seems to be working well for me.
4.3Patient Review
12/25/2020
Terazosin Hydrochloride for Enlarged Prostate with Urination Problems
I find that this treatment is effective when I avoid bladder irritants. If I stick to one cup of green tea in the morning and no Diet Coke during the day, I can usually make it through the night without having to urinate. Without terasozin, I would get up 2-3 times a night to urinate.
4.3Patient Review
11/10/2015
Terazosin Hydrochloride for Enlarged Prostate with Urination Problems
The capsules are supposed to be 5 mg, but they're only half the size of the former capsules.
4Patient Review
2/8/2020
Terazosin Hydrochloride for Enlarged Prostate with Urination Problems
This medication has helped me to sleep through the night when I previously had to wake up multiple times due to nocturia.
View All Reviews
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Patient Q&A Section about terazosin hydrochloride

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Why do you take terazosin at night?

"Take terazosin at night to avoid problems with dizziness or fainting. The doctor will start with a small dose and gradually increase it."

Answered by AI

What is terazosin hydrochloride used for?

"Terazosin relaxes blood vessels and helps to lower blood pressure. Terazosin is also used to treat benign prostatic hyperplasia (BPH)."

Answered by AI

What is an important side effect of terazosin?

"You may feel dizzy, lightheaded, or faint if you stand up too quickly after lying down. This is more common when you first start or increase your dose of terazosin, or if you stop taking it for a few days and then start again."

Answered by AI

Does terazosin make you pee?

"Terazosin helps to relax the muscles in the prostate and around the bladder opening. This may help to increase the flow of urine, and/or reduce symptoms."

Answered by AI

Clinical Trials for Terazosin Hydrochloride

Have you considered Terazosin Hydrochloride clinical trials? We made a collection of clinical trials featuring Terazosin Hydrochloride, we think they might fit your search criteria.
Have you considered Terazosin Hydrochloride clinical trials? We made a collection of clinical trials featuring Terazosin Hydrochloride, we think they might fit your search criteria.
Have you considered Terazosin Hydrochloride clinical trials? We made a collection of clinical trials featuring Terazosin Hydrochloride, we think they might fit your search criteria.
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