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What is Terazosin Hydrochloride
TerazosinThe Generic name of this drug
Treatment SummaryTerazosin is a medication used to treat benign prostatic hyperplasia and high blood pressure. It works by blocking the action of adrenaline on the alpha-1 adrenergic receptors, which helps relax the muscles in the blood vessels and prostate.
Hytrinis the brand name
Terazosin Hydrochloride Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Hytrin
Terazosin
1987
173
Approved as Treatment by the FDA
Terazosin, otherwise known as Hytrin, is approved by the FDA for 2 uses including Enlarged Prostate and Hypertensive disease .Enlarged Prostate
Hypertensive disease
Helps manage High Blood Pressure (Hypertension)
Effectiveness
How Terazosin Hydrochloride Affects PatientsTerazosin is a type of drug that helps block the actions of certain hormones in the body (alpha-1 adrenergic hormones) to help treat certain conditions.
How Terazosin Hydrochloride works in the bodyTerazosin targets certain receptors found in the blood vessels and prostate. When those receptors are blocked, the smooth muscles in those areas relax, reducing blood pressure and improving urine flow. Terazosin has also been shown to stop cell growth and cause some prostate cells to die, a process called apoptosis. This is done by increasing the expression of certain factors like TGF-beta1, p27kip1, and caspase.
When to interrupt dosage
The proposed dosage of Terazosin Hydrochloride is contingent upon the ascertained condition, for example Ureteral Calculus, Hypertensive disease and Enlarged Prostate. The measure of dosage relies upon the technique of administration (e.g. Capsule, liquid filled or Capsule - Oral) as indicated in the table below.Condition
Dosage
Administration
Hypertensive disease
10.0 mg, , 1.0 mg, 2.0 mg, 5.0 mg
, Oral, Capsule, Capsule - Oral, Tablet - Oral, Tablet, Kit; Tablet, Kit; Tablet - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral
Enlarged Prostate
10.0 mg, , 1.0 mg, 2.0 mg, 5.0 mg
, Oral, Capsule, Capsule - Oral, Tablet - Oral, Tablet, Kit; Tablet, Kit; Tablet - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral
Ureteral Calculus
10.0 mg, , 1.0 mg, 2.0 mg, 5.0 mg
, Oral, Capsule, Capsule - Oral, Tablet - Oral, Tablet, Kit; Tablet, Kit; Tablet - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral
Warnings
Terazosin Hydrochloride ContraindicationsCondition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Terazosin may interact with Pulse Frequency
Common Terazosin Hydrochloride Drug Interactions
Drug Name
Risk Level
Description
Acepromazine
Major
Terazosin may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Acepromazine.
Alfuzosin
Major
Terazosin may increase the hypotensive activities of Alfuzosin.
Amifostine
Major
Terazosin may increase the hypotensive activities of Amifostine.
Aripiprazole
Major
Terazosin may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Aripiprazole.
Aripiprazole lauroxil
Major
Terazosin may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Aripiprazole lauroxil.
Terazosin Hydrochloride Toxicity & Overdose RiskIf someone takes too much terazosin, they may have low blood pressure. To help control their heart rate and blood pressure, they should lie down and may need extra fluids or medicine to increase their blood pressure. It is important to monitor their kidney function. Since terazosin is strongly bound to proteins, dialysis is not likely to be very effective in removing the drug from the body. The lowest toxic dose of terazosin in mice is 5500mg/kg.
Terazosin Hydrochloride Novel Uses: Which Conditions Have a Clinical Trial Featuring Terazosin Hydrochloride?
39 active clinical trials are currently being conducted to assess the potential of Terazosin Hydrochloride to treat Enlarged Prostate, Ureteral Calculus and Hypertensive Disease.Condition
Clinical Trials
Trial Phases
Enlarged Prostate
21 Actively Recruiting
Phase 4, Not Applicable, Phase 2, Phase 3
Hypertensive disease
19 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3
Ureteral Calculus
0 Actively Recruiting
Terazosin Hydrochloride Reviews: What are patients saying about Terazosin Hydrochloride?
5Patient Review
8/8/2016 I experienced really great results while taking this medication for a year. However, I recently had to stop because it started causing an irregular heartbeat. Thankfully, my heart is back to normal now.
5Patient Review
4/28/2019 I began with a low dose of 1mg, and have since increased to 5mg in the morning and 5mg at night. I haven't experienced any negative side effects, save for feeling lightheaded if I stand up too quickly. The medication has been effective in controlling my urination symptoms, which is something I'm grateful for. Although I would prefer not to be taking medication at all, this treatment seems to be working well for me.
4.3Patient Review
12/25/2020 I find that this treatment is effective when I avoid bladder irritants. If I stick to one cup of green tea in the morning and no Diet Coke during the day, I can usually make it through the night without having to urinate. Without terasozin, I would get up 2-3 times a night to urinate.
4.3Patient Review
11/10/2015 The capsules are supposed to be 5 mg, but they're only half the size of the former capsules.
4Patient Review
2/8/2020 This medication has helped me to sleep through the night when I previously had to wake up multiple times due to nocturia.
4Patient Review
1/8/20143.7Patient Review
6/21/2016 I found the sexual side effects quite distressing. I lost the ability to ejaculate, and as a result, also lost the orgasm associated with it. I stopped taking it for that reason - then all the old urinary problems returned. So I'm back on it and have had to accept that lack of sexual fulfillment is now a part of my life.
3.7Patient Review
5/13/2014 This treatment is good. It helped me a lot.
3.7Patient Review
11/7/20133Patient Review
8/6/2016 I had to play around with the dosage a bit before finding one that didn't make me too dizzy and fatigued. I'm urinating much better now, but it is still a bit of a trade-off.
3Patient Review
3/20/2017 The doctor prescribed this for me to help with high blood pressure caused by pain. Unfortunately, it made it difficult to concentrate and my vision got worse. I stopped taking it once the pain subsided, but my eyes are still blurry. Make sure you stay hydrated if you go on this medication.
3Patient Review
7/16/2014 Flomax gave me some really unpleasant side effects, so I had to switch to Terazosin. So far it's been working well for my BPH with only minor headaches. It's also a lot cheaper than Flomax, so that's a bonus.
2.7Patient Review
9/12/2016 I'm a 64 year old woman who has been taking this once per day, and it's helped me a lot without any noticeable side effects. It's also very affordable, which is great.
2.3Patient Review
5/6/2016 Honestly, this was the worst headache I have ever experienced. I couldn't sleep at all, and felt nauseous and dizzy the entire time. My teeth even started hurting really badly. This drug is absolutely intolerable, and I still feel its effects 11 days later. So scary.
2Patient Review
8/29/2018 I had to stop taking this after just a few days because the side effects were so bad. My heart rate would skyrocket and I felt really sick all the time.
1Patient Review
3/24/2017 Though my issues weren't major, this treatment still helped me a lot. I don't have any severe side effects, which is great. My erections aren't perfect but they work well enough, and my blood pressure is as low as it can be without causing problems.
1Patient Review
1/16/2016 This medication definitely helped me with my urinary frequency.
Patient Q&A Section about terazosin hydrochloride
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Why do you take terazosin at night?
"Take terazosin at night to avoid problems with dizziness or fainting. The doctor will start with a small dose and gradually increase it."
Answered by AI
What is terazosin hydrochloride used for?
"Terazosin relaxes blood vessels and helps to lower blood pressure. Terazosin is also used to treat benign prostatic hyperplasia (BPH)."
Answered by AI
What is an important side effect of terazosin?
"You may feel dizzy, lightheaded, or faint if you stand up too quickly after lying down. This is more common when you first start or increase your dose of terazosin, or if you stop taking it for a few days and then start again."
Answered by AI
Does terazosin make you pee?
"Terazosin helps to relax the muscles in the prostate and around the bladder opening. This may help to increase the flow of urine, and/or reduce symptoms."
Answered by AI