← Back to Search

Writing Intervention for Cognitive Health in Older Adults

Phase 1

Recruiting

Research Sponsored by University of California, Los Angeles

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline, 6 weeks, 10 weeks

Awards & highlights

Study Summary

This trial will explore how writing about your experiences can affect the brain & body in healthy older adults. Join UCLA researchers to help find out!

Who is the study for?

Healthy adults aged 65 and older can join this UCLA study. It's not for those with chronic infections like Hepatitis C or HIV, a BMI over 35, claustrophobia, current smokers, uncontrolled medical issues, major psychiatric conditions, left-handedness, body metal implants or on steroids/opioids.Check my eligibility

What is being tested?

The study tests if writing about personal experiences once a week for six weeks impacts brain and body health in older adults. Participants will also have two neuroimaging sessions (fMRI), provide blood samples and complete questionnaires before and after the writing period at UCLA.See study design

What are the potential side effects?

There are no direct physical side effects expected from the writing intervention itself; however, participants may experience discomfort during fMRI scanning or when providing blood spot samples.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline, 6 weeks, 10 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline, 6 weeks, 10 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 6 weeks, 10 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in Amygdala Activity in response to threat

Change in Anterior Insula Activity in response to stress

Change in Dorsal Anterior Cingulate Cortex (dACC) Activity in response to stress

+6 more

Secondary outcome measures

Change in Beliefs about Aging

Change in Memory

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Writing about ExperiencesExperimental Treatment1 Intervention

Participants will be asked to write about experiences with familiar individuals in their lives.

Group II: Writing about PlacesPlacebo Group1 Intervention

Participants will be asked to write about experiences with familiar places in their lives.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Writing Intervention

2008

N/A

~170

Do I qualify?Apply below to find out

Find a Location

Logistics

Participation is compensated

You will be compensated for participating in this trial.

Who is running the clinical trial?

University of California, Los AngelesLead Sponsor

1,530 Previous Clinical Trials

10,278,002 Total Patients Enrolled

Media Library

Writing Intervention Clinical Trial Eligibility Overview. Trial Name: NCT05524597 — Phase 1

Psychology and Social Science Research Study Groups: Writing about Experiences, Writing about Places

Psychology and Social Science Clinical Trial 2023: Writing Intervention Highlights & Side Effects. Trial Name: NCT05524597 — Phase 1

Writing Intervention 2023 Treatment Timeline for Medical Study. Trial Name: NCT05524597 — Phase 1

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is penning one's experiences a secure method of self-expression for individuals?

"The safety of Writing about Experiences has been deemed to be a 1 on the scale, due to this being an initial phase trial that only offers limited data regarding efficacy and security."

Answered by AI

To what extent is this clinical trial accepting applicants?

"Affirmative. Information found on clinicaltrials.gov suggests that this medical trial is presently attempting to recruit participants, with an initial posting date of March 13th 2023 and a recent update occurring on the 17th of March 2023. A total of 200 patients will have to be gathered at 1 site for successful completion of the study."

Answered by AI

Is there still availability for people to join this research endeavor?

"Affirmative. Data hosted on clinicaltrials.gov reveals that the trial is currently in search of volunteers, having been initiated on March 13th 2023 and last modified two days later. The research necessitates 200 recruits from a single site."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Writing About Experiences and Health in Older Adults II

Naomi Eisenberger 2023. "Writing About Experiences and Health in Older Adults II". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05524597.