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Diagnostic Imaging for Tauopathies

Phase < 1
Recruiting
Research Sponsored by University of Pennsylvania
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Participants must be aged between 40 to 85 years and be both male and female
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 8 weeks
Awards & highlights

Study Summary

This trial aims to create a radiotracer to accurately detect brain diseases such as Parkinson's, Multiple System Atrophy, Progressive Supranuclear Palsy, and Frontotemporal Dementia. It is a multicenter trial with U Penn, Pitt, Yale, UCSF, and WU.

Who is the study for?
This trial is for adults aged 40-85 with Parkinson's Disease, Multiple System Atrophy, Progressive Supranuclear Palsy, Frontotemporal Dementia or healthy controls. They must understand the study and consent to participate. Pregnant women and those with major psychiatric disorders or substance abuse issues are excluded.Check my eligibility
What is being tested?
The trial tests new radiotracers' specificity using diagnostic assessments like neurologic exams and brain scans (Amyloid PET and MRI) across multiple sites including U Penn, Pitt, Yale University, UCSF, and WU.See study design
What are the potential side effects?
Potential side effects may include discomfort from the imaging procedures such as headaches or nausea post-scan. Allergic reactions to contrast agents used in MRI/PET scans could occur but are rare.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am between 40 and 85 years old.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~8 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 8 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Disease diagnosis

Trial Design

1Treatment groups
Experimental Treatment
Group I: Diagnostic AssessmentsExperimental Treatment3 Interventions
Subjects may receive an Amyloid PET scan, a brain MRI and neurological exam with diagnostic assessments.

Find a Location

Who is running the clinical trial?

University of PennsylvaniaLead Sponsor
2,005 Previous Clinical Trials
42,882,233 Total Patients Enrolled
2 Trials studying Tauopathies
140 Patients Enrolled for Tauopathies

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are elderly individuals who meet the criteria being accepted into this clinical experiment?

"The minimum age for enrollment in this experiment is 40, with the maximum being 85."

Answered by AI

How many individuals are participating in this research endeavor?

"Indeed, the data on clinicaltrials.gov demonstrates that this research is currently open to participants. The experiment was initially listed on July 20th of 2023 and underwent an update on October 14th of the same year. The team leading the trial needs 54 individuals at one medical centre for their study."

Answered by AI

Is it feasible for me to participate in this research project?

"This trial requires volunteers to meet the criteria of 40-85 years old and present with tauopathies. As such, approximately 54 individuals need to be recruited for participation."

Answered by AI

Are there opportunities to enroll in this research endeavor?

"Affirmative. According to the information accessed from clinicaltrials.gov, the trial which was first posted on July 20th 2023 is actively recruiting participants. Specifically, 54 patients need to be recruited for this study at a single medical centre."

Answered by AI
~36 spots leftby Jul 2028