Technetium Tc 99M Sestamibi

Coronary Disease, Heart Function Tests

Treatment

3 FDA approvals

1 Active Study for Technetium Tc 99M Sestamibi

What is Technetium Tc 99M Sestamibi

Technetium Tc-99m sestamibi

The Generic name of this drug

Treatment Summary

Tetrakis (2-methoxyisobutylisocyanide) copper (I) tetrafluoroborate is a chemical compound used in the imaging agent Cardiolite to evaluate blood flow and heart muscle function.

Technetium Tc 99m Sestamibi

is the brand name

Technetium Tc 99M Sestamibi Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Technetium Tc 99m Sestamibi

Technetium Tc-99m sestamibi

2009

5

Approved as Treatment by the FDA

Technetium Tc-99m sestamibi, also known as Technetium Tc 99m Sestamibi, is approved by the FDA for 3 uses including Coronary Artery Disease (CAD) and Coronary Disease .

Coronary Artery Disease (CAD)

Coronary Disease

Heart Function Tests

When to interrupt dosage

The suggested dosage of Technetium Tc 99M Sestamibi is contingent upon the diagnosed condition, such as Perfusion Scintigraphy, Primary hyperthyroidism and Hyperthyroidism. The amount likewise differs as per the method of delivery outlined in the table below.

Condition

Dosage

Administration

Coronary Disease

, 1.0 mg/mL, 0.1 mg/mL

, Injection - Intravenous, Intravenous, Injection, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Parenteral, Parenteral, Injection, powder, for solution, Injection, powder, for solution - Intravenous

Heart Function Tests

, 1.0 mg/mL, 0.1 mg/mL

, Injection - Intravenous, Intravenous, Injection, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Parenteral, Parenteral, Injection, powder, for solution, Injection, powder, for solution - Intravenous

Warnings

There are 20 known major drug interactions with Technetium Tc 99M Sestamibi.

Common Technetium Tc 99M Sestamibi Drug Interactions

Drug Name

Risk Level

Description

Abemaciclib

Moderate

The serum concentration of Abemaciclib can be increased when it is combined with Technetium Tc-99m sestamibi.

Avatrombopag

Moderate

The serum concentration of Avatrombopag can be increased when it is combined with Technetium Tc-99m sestamibi.

Axitinib

Moderate

The serum concentration of Axitinib can be increased when it is combined with Technetium Tc-99m sestamibi.

Belantamab mafodotin

Moderate

The serum concentration of Belantamab mafodotin can be increased when it is combined with Technetium Tc-99m sestamibi.

Bendamustine

Moderate

The serum concentration of Bendamustine can be increased when it is combined with Technetium Tc-99m sestamibi.

Technetium Tc 99M Sestamibi Novel Uses: Which Conditions Have a Clinical Trial Featuring Technetium Tc 99M Sestamibi?

760 active clinical trials are investigating the potential of Technetium Tc 99M Sestamibi in alleviating Coronary Artery Disease (CAD), Hyperthyroidism and Primary hyperthyroidism.

Condition

Clinical Trials

Trial Phases

Coronary Disease

1 Actively Recruiting

Not Applicable

Heart Function Tests

0 Actively Recruiting

Patient Q&A Section about technetium tc 99m sestamibi

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the side effects of technetium 99?

"Blurred vision, chest pain or discomfort, dizziness, faintness or lightheadedness when getting up suddenly from a lying or sitting position, fast, slow or irregular heartbeat, hives, itching or redness, lightheadedness, no blood pressure or pulse, pounding or rapid pulse."

Answered by AI

What is technetium Tc 99m Sestamibi used for?

"Technetium 99m sestamibi (MIBI) is a radiopharmaceutical used to evaluate pathology within the cardiac, breast, and parathyroid tissues. It is part of the radioactive diagnostic agents class of medications, characterized as a lipophilic cationic radiotracer."

Answered by AI

What is technetium sestamibi scan?

"The technetium slowly travels through the bloodstream and collects in the area of greatest uptake which is the overactive parathyroid gland(s), and gives off radiation that can be read by a gamma camera

An imaging test used to find overactive parathyroid glands (four pea-sized glands found on the thyroid) and breast cancer cells, and to diagnose heart disease. The patient receives an injection of a small amount of a radioactive substance called technetium which is bound to another substance called sestamibi. The technetium slowly travels through the bloodstream and collects in the area of greatest uptake which is the overactive parathyroid gland(s), and gives off radiation that can be read by a gamma camera."

Answered by AI

Which diagnostic test requires the intravenous administration of technetium 99mtc sestamibi before the procedure?

"Technetium TC 99M Sestamibi is indicated for planar imaging of the breast to assist in the evaluation of breast lesions in patients with an abnormal mammogram or a palpable breast mass."

Answered by AI

Clinical Trials for Technetium Tc 99M Sestamibi

Image of National Institutes of Health Clinical Center in Bethesda, United States.

Low SAR MRI Scans for Coronary Heart Disease

18 - 100
All Sexes
Bethesda, MD

Background: Researchers are testing version of a system known as a magnetic resonance imagining (MRI) scanner that uses strong magnetic fields, radio waves and the like to create images of the organs in the body. It uses lower energy levels than other MRI scanners. This may help scan people with metal devices in their body, or in invasive heart procedures using metal tools. Objective: To test a new MRI scanner and software changes to create better pictures. Eligibility: People with disease and healthy volunteers, ages 18 and older. Design: Participants will be screened with blood tests. Participants may have both the new MRI and a conventional MRI or only the new one. If 2 are done, they must be within 60 days. For both MRI versions, participants lie on a table that slides into a large tube. During scans, they will hold their breath for up to 20 seconds at a time. Heart activity will be measured by wires connected to pads on the skin. A flexible belt may be used to monitor their breathing. They will be in the scanner up to 2 hours. Participants can agree to have a dye called gadolinium injected into their arm during the scan. This brightens the pictures. Participants can agree to take a drug called a vasodilator. This helps detect areas of the heart with abnormal blood supply. Scans of the heart are taken before, during, and after they get the medicine. The drug may cause temporary chest pain or shortness of breath. They may get other drugs to relieve these symptoms. Sponsoring Institution: National Heart, Lung, and Blood Institute

Recruiting
Has No Placebo

National Institutes of Health Clinical Center

Adrienne E Campbell, Ph.D.