Tagamet Hb

Systemic Mastocytosis, Gastric hypersecretion, NSAID use + 12 more
Treatment
7 FDA approvals
20 Active Studies for Tagamet Hb

What is Tagamet Hb

CimetidineThe Generic name of this drug
Treatment SummaryCimetidine is a type of drug known as a histamine congener. It works by blocking histamine from binding to histamine H2 receptors, which helps reduce the production of stomach acid. Cimetidine can also reduce the production of pepsin and gastrins and inhibit the activity of an enzyme called cytochrome P-450, which may be useful in neoadjuvant therapy.
Cimetidineis the brand name
Tagamet Hb Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Cimetidine
Cimetidine
1994
90

Approved as Treatment by the FDA

Cimetidine, also known as Cimetidine, is approved by the FDA for 7 uses which include Heartburn and Gastric ulcer .
Heartburn
Helps manage Gastro-esophageal Reflux Disease (GERD)
Gastric ulcer
Zollinger-Ellison Syndrome
Helps manage Zollinger-Ellison Syndrome
Duodenal Ulcer
Gastric hypersecretion
Helps manage Gastric hypersecretion
Systemic Mastocytosis
Helps manage Systemic Mastocytosis
Adenoma
Helps manage multiple endocrine adenomas

Effectiveness

How Tagamet Hb Affects PatientsCimetidine helps to reduce how much acid the stomach produces, both during the day and at night. It is used to treat digestive issues like stomach or duodenal ulcers, acid reflux, and conditions that cause too much acid to be made in the stomach. Taking cimetidine can also affect how the body processes certain medications, as well as increase the amount of certain bacteria in the stomach.
How Tagamet Hb works in the bodyCimetidine works by blocking the effects of histamine on the stomach. It attaches to a special receptor on the cells in the stomach and prevents histamine from binding. This stops the stomach from producing too much acid, reducing the amount of acid in the stomach and its volume.

When to interrupt dosage

The proposed dosage of Tagamet Hb is contingent upon the diagnosed condition, for instance Acid indigestion, Cystic Fibrosis (CF) and Systemic Mastocytosis. The amount of dosage is also subject to the procedure of delivery (e.g. Liquid or Intramuscular; Intravenous) featured in the following table.
Condition
Dosage
Administration
Duodenal Ulcer
300.0 mg/mL, , 300.0 mg, 400.0 mg, 200.0 mg, 150.0 mg/mL, 400.0 mg/mL, 800.0 mg, 6.0 mg/mL, 60.0 mg/mL, 600.0 mg, 100.0 mg, 0.1 mg/mg, 0.05 mg/mg
Liquid, Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, , Oral, Liquid - Oral, Gel, Solution, Tablet - Oral, Injection, solution - Intramuscular; Intravenous, Injection, solution, Tablet, film coated, Tablet, Intravenous, Tablet, film coated - Oral, Liquid - Intravenous, Cream, Injection, solution - Intravenous, Cream - Topical, Topical, Solution - Intramuscular; Intravenous, Solution - Oral, Gel - Topical
Duodenum
300.0 mg/mL, , 300.0 mg, 400.0 mg, 200.0 mg, 150.0 mg/mL, 400.0 mg/mL, 800.0 mg, 6.0 mg/mL, 60.0 mg/mL, 600.0 mg, 100.0 mg, 0.1 mg/mg, 0.05 mg/mg
Liquid, Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, , Oral, Liquid - Oral, Gel, Solution, Tablet - Oral, Injection, solution - Intramuscular; Intravenous, Injection, solution, Tablet, film coated, Tablet, Intravenous, Tablet, film coated - Oral, Liquid - Intravenous, Cream, Injection, solution - Intravenous, Cream - Topical, Topical, Solution - Intramuscular; Intravenous, Solution - Oral, Gel - Topical
Zollinger-Ellison Syndrome
300.0 mg/mL, , 300.0 mg, 400.0 mg, 200.0 mg, 150.0 mg/mL, 400.0 mg/mL, 800.0 mg, 6.0 mg/mL, 60.0 mg/mL, 600.0 mg, 100.0 mg, 0.1 mg/mg, 0.05 mg/mg
Liquid, Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, , Oral, Liquid - Oral, Gel, Solution, Tablet - Oral, Injection, solution - Intramuscular; Intravenous, Injection, solution, Tablet, film coated, Tablet, Intravenous, Tablet, film coated - Oral, Liquid - Intravenous, Cream, Injection, solution - Intravenous, Cream - Topical, Topical, Solution - Intramuscular; Intravenous, Solution - Oral, Gel - Topical
Systemic Mastocytosis
300.0 mg/mL, , 300.0 mg, 400.0 mg, 200.0 mg, 150.0 mg/mL, 400.0 mg/mL, 800.0 mg, 6.0 mg/mL, 60.0 mg/mL, 600.0 mg, 100.0 mg, 0.1 mg/mg, 0.05 mg/mg
Liquid, Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, , Oral, Liquid - Oral, Gel, Solution, Tablet - Oral, Injection, solution - Intramuscular; Intravenous, Injection, solution, Tablet, film coated, Tablet, Intravenous, Tablet, film coated - Oral, Liquid - Intravenous, Cream, Injection, solution - Intravenous, Cream - Topical, Topical, Solution - Intramuscular; Intravenous, Solution - Oral, Gel - Topical
Indigestion
300.0 mg/mL, , 300.0 mg, 400.0 mg, 200.0 mg, 150.0 mg/mL, 400.0 mg/mL, 800.0 mg, 6.0 mg/mL, 60.0 mg/mL, 600.0 mg, 100.0 mg, 0.1 mg/mg, 0.05 mg/mg
Liquid, Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, , Oral, Liquid - Oral, Gel, Solution, Tablet - Oral, Injection, solution - Intramuscular; Intravenous, Injection, solution, Tablet, film coated, Tablet, Intravenous, Tablet, film coated - Oral, Liquid - Intravenous, Cream, Injection, solution - Intravenous, Cream - Topical, Topical, Solution - Intramuscular; Intravenous, Solution - Oral, Gel - Topical
Heartburn
300.0 mg/mL, , 300.0 mg, 400.0 mg, 200.0 mg, 150.0 mg/mL, 400.0 mg/mL, 800.0 mg, 6.0 mg/mL, 60.0 mg/mL, 600.0 mg, 100.0 mg, 0.1 mg/mg, 0.05 mg/mg
Liquid, Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, , Oral, Liquid - Oral, Gel, Solution, Tablet - Oral, Injection, solution - Intramuscular; Intravenous, Injection, solution, Tablet, film coated, Tablet, Intravenous, Tablet, film coated - Oral, Liquid - Intravenous, Cream, Injection, solution - Intravenous, Cream - Topical, Topical, Solution - Intramuscular; Intravenous, Solution - Oral, Gel - Topical
Gastric hypersecretion
300.0 mg/mL, , 300.0 mg, 400.0 mg, 200.0 mg, 150.0 mg/mL, 400.0 mg/mL, 800.0 mg, 6.0 mg/mL, 60.0 mg/mL, 600.0 mg, 100.0 mg, 0.1 mg/mg, 0.05 mg/mg
Liquid, Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, , Oral, Liquid - Oral, Gel, Solution, Tablet - Oral, Injection, solution - Intramuscular; Intravenous, Injection, solution, Tablet, film coated, Tablet, Intravenous, Tablet, film coated - Oral, Liquid - Intravenous, Cream, Injection, solution - Intravenous, Cream - Topical, Topical, Solution - Intramuscular; Intravenous, Solution - Oral, Gel - Topical
NSAID use
300.0 mg/mL, , 300.0 mg, 400.0 mg, 200.0 mg, 150.0 mg/mL, 400.0 mg/mL, 800.0 mg, 6.0 mg/mL, 60.0 mg/mL, 600.0 mg, 100.0 mg, 0.1 mg/mg, 0.05 mg/mg
Liquid, Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, , Oral, Liquid - Oral, Gel, Solution, Tablet - Oral, Injection, solution - Intramuscular; Intravenous, Injection, solution, Tablet, film coated, Tablet, Intravenous, Tablet, film coated - Oral, Liquid - Intravenous, Cream, Injection, solution - Intravenous, Cream - Topical, Topical, Solution - Intramuscular; Intravenous, Solution - Oral, Gel - Topical
Cystic Fibrosis (CF)
300.0 mg/mL, , 300.0 mg, 400.0 mg, 200.0 mg, 150.0 mg/mL, 400.0 mg/mL, 800.0 mg, 6.0 mg/mL, 60.0 mg/mL, 600.0 mg, 100.0 mg, 0.1 mg/mg, 0.05 mg/mg
Liquid, Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, , Oral, Liquid - Oral, Gel, Solution, Tablet - Oral, Injection, solution - Intramuscular; Intravenous, Injection, solution, Tablet, film coated, Tablet, Intravenous, Tablet, film coated - Oral, Liquid - Intravenous, Cream, Injection, solution - Intravenous, Cream - Topical, Topical, Solution - Intramuscular; Intravenous, Solution - Oral, Gel - Topical
Acid indigestion
300.0 mg/mL, , 300.0 mg, 400.0 mg, 200.0 mg, 150.0 mg/mL, 400.0 mg/mL, 800.0 mg, 6.0 mg/mL, 60.0 mg/mL, 600.0 mg, 100.0 mg, 0.1 mg/mg, 0.05 mg/mg
Liquid, Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, , Oral, Liquid - Oral, Gel, Solution, Tablet - Oral, Injection, solution - Intramuscular; Intravenous, Injection, solution, Tablet, film coated, Tablet, Intravenous, Tablet, film coated - Oral, Liquid - Intravenous, Cream, Injection, solution - Intravenous, Cream - Topical, Topical, Solution - Intramuscular; Intravenous, Solution - Oral, Gel - Topical
NSAID Associated Gastric Ulcers
300.0 mg/mL, , 300.0 mg, 400.0 mg, 200.0 mg, 150.0 mg/mL, 400.0 mg/mL, 800.0 mg, 6.0 mg/mL, 60.0 mg/mL, 600.0 mg, 100.0 mg, 0.1 mg/mg, 0.05 mg/mg
Liquid, Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, , Oral, Liquid - Oral, Gel, Solution, Tablet - Oral, Injection, solution - Intramuscular; Intravenous, Injection, solution, Tablet, film coated, Tablet, Intravenous, Tablet, film coated - Oral, Liquid - Intravenous, Cream, Injection, solution - Intravenous, Cream - Topical, Topical, Solution - Intramuscular; Intravenous, Solution - Oral, Gel - Topical
Adenoma
300.0 mg/mL, , 300.0 mg, 400.0 mg, 200.0 mg, 150.0 mg/mL, 400.0 mg/mL, 800.0 mg, 6.0 mg/mL, 60.0 mg/mL, 600.0 mg, 100.0 mg, 0.1 mg/mg, 0.05 mg/mg
Liquid, Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, , Oral, Liquid - Oral, Gel, Solution, Tablet - Oral, Injection, solution - Intramuscular; Intravenous, Injection, solution, Tablet, film coated, Tablet, Intravenous, Tablet, film coated - Oral, Liquid - Intravenous, Cream, Injection, solution - Intravenous, Cream - Topical, Topical, Solution - Intramuscular; Intravenous, Solution - Oral, Gel - Topical
Gastrointestinal Symptoms
300.0 mg/mL, , 300.0 mg, 400.0 mg, 200.0 mg, 150.0 mg/mL, 400.0 mg/mL, 800.0 mg, 6.0 mg/mL, 60.0 mg/mL, 600.0 mg, 100.0 mg, 0.1 mg/mg, 0.05 mg/mg
Liquid, Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, , Oral, Liquid - Oral, Gel, Solution, Tablet - Oral, Injection, solution - Intramuscular; Intravenous, Injection, solution, Tablet, film coated, Tablet, Intravenous, Tablet, film coated - Oral, Liquid - Intravenous, Cream, Injection, solution - Intravenous, Cream - Topical, Topical, Solution - Intramuscular; Intravenous, Solution - Oral, Gel - Topical
Heartburn
300.0 mg/mL, , 300.0 mg, 400.0 mg, 200.0 mg, 150.0 mg/mL, 400.0 mg/mL, 800.0 mg, 6.0 mg/mL, 60.0 mg/mL, 600.0 mg, 100.0 mg, 0.1 mg/mg, 0.05 mg/mg
Liquid, Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, , Oral, Liquid - Oral, Gel, Solution, Tablet - Oral, Injection, solution - Intramuscular; Intravenous, Injection, solution, Tablet, film coated, Tablet, Intravenous, Tablet, film coated - Oral, Liquid - Intravenous, Cream, Injection, solution - Intravenous, Cream - Topical, Topical, Solution - Intramuscular; Intravenous, Solution - Oral, Gel - Topical
Gastric ulcer
300.0 mg/mL, , 300.0 mg, 400.0 mg, 200.0 mg, 150.0 mg/mL, 400.0 mg/mL, 800.0 mg, 6.0 mg/mL, 60.0 mg/mL, 600.0 mg, 100.0 mg, 0.1 mg/mg, 0.05 mg/mg
Liquid, Intramuscular; Intravenous, Liquid - Intramuscular; Intravenous, , Oral, Liquid - Oral, Gel, Solution, Tablet - Oral, Injection, solution - Intramuscular; Intravenous, Injection, solution, Tablet, film coated, Tablet, Intravenous, Tablet, film coated - Oral, Liquid - Intravenous, Cream, Injection, solution - Intravenous, Cream - Topical, Topical, Solution - Intramuscular; Intravenous, Solution - Oral, Gel - Topical

Warnings

Tagamet Hb has one caveat and should not be consumed when encountering any of the conditions detailed in the below table.Tagamet Hb Contraindications
Condition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Cimetidine may interact with Toxoplasma Infections
There are 20 known major drug interactions with Tagamet Hb.
Common Tagamet Hb Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The metabolism of Abemaciclib can be decreased when combined with Cimetidine.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be decreased when combined with Cimetidine.
Alectinib
Major
The metabolism of Alectinib can be decreased when combined with Cimetidine.
Alpelisib
Major
The metabolism of Alpelisib can be decreased when combined with Cimetidine.
Anagrelide
Major
The metabolism of Anagrelide can be decreased when combined with Cimetidine.
Tagamet Hb Toxicity & Overdose RiskIn the unlikely event of cimetidine overdose, it is essential to make sure the patient can breathe and their heart is functioning normally. Monitor the patient's status and provide treatments that help with their symptoms. If needed, a doctor may decide to do a gastric lavage and give activated charcoal.

Tagamet Hb Novel Uses: Which Conditions Have a Clinical Trial Featuring Tagamet Hb?

27 active trials are examining if Tagamet Hb is able to ameliorate Heartburn, Duodenal Ulcer and Duodenal inflammation.
Condition
Clinical Trials
Trial Phases
Gastrointestinal Symptoms
1 Actively Recruiting
Phase 1, Phase 2
Gastric ulcer
0 Actively Recruiting
Gastric hypersecretion
0 Actively Recruiting
Duodenal Ulcer
0 Actively Recruiting
Acid indigestion
0 Actively Recruiting
Cystic Fibrosis (CF)
1 Actively Recruiting
Phase 2
Heartburn
11 Actively Recruiting
Phase 3, Phase 4, Phase 2, Not Applicable, Early Phase 1
Duodenum
0 Actively Recruiting
NSAID use
0 Actively Recruiting
NSAID Associated Gastric Ulcers
0 Actively Recruiting
Adenoma
0 Actively Recruiting
Indigestion
11 Actively Recruiting
Phase 3, Not Applicable, Early Phase 1, Phase 2, Phase 1
Zollinger-Ellison Syndrome
0 Actively Recruiting
Systemic Mastocytosis
1 Actively Recruiting
Phase 1
Heartburn
4 Actively Recruiting
Phase 3, Not Applicable

Tagamet Hb Reviews: What are patients saying about Tagamet Hb?

5Patient Review
2/27/2014
Tagamet Hb for Stomach Ulcer
I've been using Tagamet for decades now, and it's always helped me whenever I have an ulcer flare-up. I find that there are fewer side-effects with this drug than with other medications, which is really important to me because I never know how I will react to a new drug.
5Patient Review
8/29/2019
Tagamet Hb for Heartburn
Really helped me when I was struggling.
5Patient Review
9/13/2010
Tagamet Hb for Stomach Ulcer
I felt better within 30 minutes of taking this medication. It's been a lifesaver for my gallbladder issues.
5Patient Review
6/7/2010
Tagamet Hb for Heartburn
Could taking tagament lead to high liver enzyme levels?
5Patient Review
7/20/2008
Tagamet Hb for Heartburn
5Patient Review
9/26/2008
Tagamet Hb for Heartburn
5Patient Review
9/29/2011
Tagamet Hb for Stress Ulcer Prevention
Tagamet is also useful for people on methadone. It prevents the liver from releasing too much of the drug at one time. I found that by taking it half an hour before and after my dose, I got a much better result. As for the price, you can buy it at Wal-Mart for only $4.88 (07/15/2011). The only downside is that you have to be consistent with it or it will stop working altogether.
4.3Patient Review
1/10/2009
Tagamet Hb for Heartburn
I found that Tagament worked better than my prescription Aciphex. I experienced fewer side effects, like bloating, with this medication.
4Patient Review
4/6/2012
Tagamet Hb for Condition in which Stomach Acid is Pushed Into the Esophagus
I'm wondering if my recent high blood pressure readings could be a result of this medication?
4Patient Review
12/26/2007
Tagamet Hb for Condition in which Stomach Acid is Pushed Into the Esophagus
3.7Patient Review
10/22/2009
Tagamet Hb for Heartburn
Tagamet works just as well as Nexium for me, but it's much cheaper. I only have heartburn and reflux occasionally now, mostly if I overeat. All in all, this drug is a great GERD treatment option.
3Patient Review
11/6/2011
Tagamet Hb for Condition in which Stomach Acid is Pushed Into the Esophagus
I've been taking Tagamet for a long time, and it's still the best stomach medication out there in my opinion.

Patient Q&A Section about tagamet hb

What is Tagamet HB used for?

"This medication is used to treat occasional heartburn that is caused by too much acid in the stomach. It is also used to prevent heartburn and acid indigestion that is caused by certain foods and beverages." - Anonymous Online Contributor

Unverified Answer

Is Tagamet and Zantac the same thing?

"Zantac is also used to treat heartburn and other symptoms of GERD. Both Tagamet and Zantac are available as over-the-counter (OTC) and prescription medications.

Tagamet and Zantac are both histamine receptor antagonists used to treat and prevent ulcers. Tagamet is also used to treat conditions that cause the stomach to produce too much acid, and to treat gastroesophageal reflux disease (GERD). Zantac is also used to treat heartburn and other symptoms of GERD. Both Tagamet and Zantac are available as over-the-counter (OTC) and prescription medications." - Anonymous Online Contributor

Unverified Answer

Is Tagamet HB over-the-counter?

"Cimetidine is a medication used to treat heartburn and other stomach-acid related issues. It is available via prescription or over-the-counter." - Anonymous Online Contributor

Unverified Answer

Why was Tagamet taken off the market?

"The FDA has reported that some medicines may contain high levels of N-Nitrosodimethylamine (NDMA), a substance classified as a 'probable human carcinogen' by the World Health Organization." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Clinical Trials for Tagamet Hb

Have you considered Tagamet Hb clinical trials? We made a collection of clinical trials featuring Tagamet Hb, we think they might fit your search criteria.
Have you considered Tagamet Hb clinical trials? We made a collection of clinical trials featuring Tagamet Hb, we think they might fit your search criteria.
Have you considered Tagamet Hb clinical trials? We made a collection of clinical trials featuring Tagamet Hb, we think they might fit your search criteria.
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
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