Cognitive Behavioral Therapy for Avoidant Restrictive Food Intake Disorder

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Avoidant Restrictive Food Intake Disorder+7 MoreCognitive Behavioral Therapy - Behavioral
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

Randomized controlled trial of an exposure-based behavioral treatment (CBT) in adults with functional dyspepsia who meet criteria for avoidant/restrictive food intake disorder (ARFID) with weight loss.

Eligible Conditions
  • Avoidant Restrictive Food Intake Disorder
  • Appetite Regulation
  • Indigestion
  • Behavioral Medicine
  • Eating Disorders
  • Cognitive Behavioral Therapy
  • Postprandial Distress Syndrome

Treatment Effectiveness

Study Objectives

5 Primary · 1 Secondary · Reporting Duration: Throughout study completion, an average of 3 years

Year 3
Assessment completion
Enrollment
Interventionist Fidelity ratings
Retention
Week 12
Client Satisfaction
Week 0
Dyspepsia

Trial Safety

Side Effects for

MESH
8%irritability
This histogram enumerates side effects from a completed 2021 Phase 4 trial (NCT04135937) in the MESH ARM group. Side effects include: irritability with 8%.

Trial Design

2 Treatment Groups

Usual Care
1 of 2
Cognitive Behavioral Therapy
1 of 2

Active Control

Experimental Treatment

50 Total Participants · 2 Treatment Groups

Primary Treatment: Cognitive Behavioral Therapy · No Placebo Group · N/A

Cognitive Behavioral Therapy
Behavioral
Experimental Group · 1 Intervention: Cognitive Behavioral Therapy · Intervention Types: Behavioral
Usual CareNoIntervention Group · 1 Intervention: Usual Care · Intervention Types:
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Cognitive Behavioral Therapy
2016
Completed Phase 4
~2380

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: throughout study completion, an average of 3 years

Who is running the clinical trial?

Massachusetts General HospitalLead Sponsor
2,703 Previous Clinical Trials
30,853,158 Total Patients Enrolled
1 Trials studying Avoidant Restrictive Food Intake Disorder
35 Patients Enrolled for Avoidant Restrictive Food Intake Disorder
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NIH
2,148 Previous Clinical Trials
4,074,729 Total Patients Enrolled
Helen Burton Murray, PhDPrincipal InvestigatorMassachusetts General Hospital

Eligibility Criteria

Age 18+ · All Participants · 9 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You are not stable for outpatient care.
You are able to communicate in English.