Suprax

Tonsillitis, Gonorrhea, Otitis Media + 12 more
Treatment
15 FDA approvals
8 Active Studies for Suprax

What is Suprax

CefiximeThe Generic name of this drug
Treatment SummaryCefixime is an antibiotic medication in the cephalosporin family. It is designed to treat infections caused by bacteria and is more resistant to beta-lactamase enzymes than other antibiotics in its class. Cefixime works by blocking the production of a certain protein in the bacteria cell wall, which prevents the bacteria from growing and multiplying.
Supraxis the brand name
image of different drug pills on a surface
Suprax Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Suprax
Cefixime
2004
39

Approved as Treatment by the FDA

Cefixime, also known as Suprax, is approved by the FDA for 15 uses including Sinusitis and Bronchitis .
Sinusitis
Bronchitis
Streptococcal Pharyngitis
Acute Exacerbations of Chronic Bronchitis caused by Haemophilus Influenzae
uncomplicated Gonorrhea
Acute Exacerbation of Chronic Bronchitis caused by Streptococcus Pneumoniae
Uncomplicated Urinary Tract Infections
Bacterial Sinusitis
bacterial otitis media
Tonsillitis streptococcal
Gonorrhea
Urinary tract infection
Bronchitis, Chronic
Otitis Media
Tonsillitis

Effectiveness

How Suprax Affects PatientsCefixime is an antibiotic that belongs to the cephalosporin family, which also includes ceftriaxone and cefotaxime. Cefixime is particularly effective against bacteria that has become resistant to penicillins and some other cephalosporins because it does not get broken down by beta-lactamase enzymes. Cefixime works by stopping the bacteria from making the substances it needs to build its cell walls.
How Suprax works in the bodyCefixime is an antibiotic that works by blocking the growth of bacteria. It does this by targeting certain proteins inside the bacterial cell wall. This stops the cell from being able to form a protective wall around itself, which leads to its destruction. Cefixime may also interfere with the bacteria's ability to prevent its own destruction.

When to interrupt dosage

The measure of Suprax is predicated upon the diagnosed affliction, like bacterial rhinosinusitis, Streptococcal Pharyngitis and Tonsillitis. The amount additionally fluctuates as per the procedure of delivery (e.g. Powder, for suspension - Oral or Tablet - Oral) featured in the table below.
Condition
Dosage
Administration
Gonorrhea
, 400.0 mg, 100.0 mg, 200.0 mg, 200.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL
, Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, chewable - Oral, Tablet, chewable, Powder, for suspension, Powder, for suspension - Oral, Powder, for solution, Powder, for solution - Oral
Dysentery, Bacillary
, 400.0 mg, 100.0 mg, 200.0 mg, 200.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL
, Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, chewable - Oral, Tablet, chewable, Powder, for suspension, Powder, for suspension - Oral, Powder, for solution, Powder, for solution - Oral
Community Acquired Pneumonia (CAP)
, 400.0 mg, 100.0 mg, 200.0 mg, 200.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL
, Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, chewable - Oral, Tablet, chewable, Powder, for suspension, Powder, for suspension - Oral, Powder, for solution, Powder, for solution - Oral
Bronchitis
, 400.0 mg, 100.0 mg, 200.0 mg, 200.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL
, Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, chewable - Oral, Tablet, chewable, Powder, for suspension, Powder, for suspension - Oral, Powder, for solution, Powder, for solution - Oral
Tonsillitis
, 400.0 mg, 100.0 mg, 200.0 mg, 200.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL
, Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, chewable - Oral, Tablet, chewable, Powder, for suspension, Powder, for suspension - Oral, Powder, for solution, Powder, for solution - Oral
Gonorrhea
, 400.0 mg, 100.0 mg, 200.0 mg, 200.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL
, Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, chewable - Oral, Tablet, chewable, Powder, for suspension, Powder, for suspension - Oral, Powder, for solution, Powder, for solution - Oral
Urinary tract infection
, 400.0 mg, 100.0 mg, 200.0 mg, 200.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL
, Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, chewable - Oral, Tablet, chewable, Powder, for suspension, Powder, for suspension - Oral, Powder, for solution, Powder, for solution - Oral
Otitis Media
, 400.0 mg, 100.0 mg, 200.0 mg, 200.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL
, Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, chewable - Oral, Tablet, chewable, Powder, for suspension, Powder, for suspension - Oral, Powder, for solution, Powder, for solution - Oral
Lyme Disease
, 400.0 mg, 100.0 mg, 200.0 mg, 200.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL
, Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, chewable - Oral, Tablet, chewable, Powder, for suspension, Powder, for suspension - Oral, Powder, for solution, Powder, for solution - Oral
Sinusitis
, 400.0 mg, 100.0 mg, 200.0 mg, 200.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL
, Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, chewable - Oral, Tablet, chewable, Powder, for suspension, Powder, for suspension - Oral, Powder, for solution, Powder, for solution - Oral
Sinusitis
, 400.0 mg, 100.0 mg, 200.0 mg, 200.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL
, Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, chewable - Oral, Tablet, chewable, Powder, for suspension, Powder, for suspension - Oral, Powder, for solution, Powder, for solution - Oral
Salmonella Infections
, 400.0 mg, 100.0 mg, 200.0 mg, 200.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL
, Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, chewable - Oral, Tablet, chewable, Powder, for suspension, Powder, for suspension - Oral, Powder, for solution, Powder, for solution - Oral
Streptococcal Pharyngitis
, 400.0 mg, 100.0 mg, 200.0 mg, 200.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL
, Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, chewable - Oral, Tablet, chewable, Powder, for suspension, Powder, for suspension - Oral, Powder, for solution, Powder, for solution - Oral
Bronchitis, Chronic
, 400.0 mg, 100.0 mg, 200.0 mg, 200.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL
, Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, chewable - Oral, Tablet, chewable, Powder, for suspension, Powder, for suspension - Oral, Powder, for solution, Powder, for solution - Oral
Disease
, 400.0 mg, 100.0 mg, 200.0 mg, 200.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL
, Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, chewable - Oral, Tablet, chewable, Powder, for suspension, Powder, for suspension - Oral, Powder, for solution, Powder, for solution - Oral

Warnings

Suprax has one contraindication and its ingestion should be avoided when suffering from any of the conditions presented in the following table.Suprax Contraindications
Condition
Risk Level
Notes
Pulse Frequency
Do Not Combine
There are 20 known major drug interactions with Suprax.
Common Suprax Drug Interactions
Drug Name
Risk Level
Description
Vibrio cholerae CVD 103-HgR strain live antigen
Major
The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Cefixime.
Abciximab
Minor
The therapeutic efficacy of Abciximab can be decreased when used in combination with Cefixime.
Alteplase
Minor
The therapeutic efficacy of Alteplase can be decreased when used in combination with Cefixime.
Amediplase
Minor
The therapeutic efficacy of Amediplase can be decreased when used in combination with Cefixime.
Ancrod
Minor
The therapeutic efficacy of Ancrod can be decreased when used in combination with Cefixime.
Suprax Toxicity & Overdose RiskOverdosing on ibuprofen can result in symptoms such as bloody urine, diarrhea, nausea, stomach pain, and vomiting.
image of a doctor in a lab doing drug, clinical research

Suprax Novel Uses: Which Conditions Have a Clinical Trial Featuring Suprax?

11 active studies are presently investigating the potential of Suprax to treat Acute Exacerbations of Chronic Bronchitis caused by Streptococcus Pneumoniae, Bacterial Rhinosinusitis and Tonsillitis.
Condition
Clinical Trials
Trial Phases
Gonorrhea
0 Actively Recruiting
Bronchitis, Chronic
0 Actively Recruiting
Tonsillitis
0 Actively Recruiting
Urinary tract infection
0 Actively Recruiting
Community Acquired Pneumonia (CAP)
5 Actively Recruiting
Not Applicable, Phase 1, Phase 3
Dysentery, Bacillary
0 Actively Recruiting
Bronchitis
0 Actively Recruiting
Sinusitis
0 Actively Recruiting
Gonorrhea
0 Actively Recruiting
Salmonella Infections
0 Actively Recruiting
Streptococcal Pharyngitis
0 Actively Recruiting
Sinusitis
0 Actively Recruiting
Disease
0 Actively Recruiting
Lyme Disease
3 Actively Recruiting
Phase 1, Phase 2, Phase 3, Not Applicable
Otitis Media
0 Actively Recruiting

Suprax Reviews: What are patients saying about Suprax?

5Patient Review
2/3/2012
Suprax for Bronchitis
I'm a 65-year-old man who caught a throat, nose, and sinus infection from my 22-month-old grandson. I started feeling better after only two days and was able to go back to work after two more. The only side effect was terrible gas.
4.7Patient Review
9/4/2014
Suprax for Urinary Tract Infection
Suprax is great for UTIs and doesn't make me incredibly nauseous like other drugs have in the past. However, it is on the expensive side and pharmacies don't always keep it in stock. So, if you're thinking of using this medication be aware that you may have to wait a few days for it to be ordered.
4.3Patient Review
1/8/2012
Suprax for Acute Infection of the Nose, Throat or Sinus
I've taken a variety of antibiotics over the years, and this was by far the WORST. The uncontrollable diarrhea made it really tough to leave the house; on top of that, it caused a yeast infection which took weeks to recover from. If you can help it, steer clear of this one.
3.7Patient Review
10/30/2013
Suprax for Infection of the Middle Ear by H. Influenzae Bacteria
Worked to clear my uti but caused TERRIBLE diarrhea, gas and stomach pain. I've been off it for over a week and the diarrhea still won't stop. Now I have to go to a gastroenterologist to be checked out for C. Diff. So after paying $100 for 5 pills of this poison now I'm going to have to shell out even more money to see a gastro specialist.
3Patient Review
3/13/2012
Suprax for Urinary Tract Infection
Suprax was given to my 2 year old son, and it's the only thing that ever worked for him.
3Patient Review
4/12/2012
Suprax for Middle Ear Infection
I experienced improvement for the first few days, but then on day four I started having terrible stomach cramps which led to intense diarrhea. I had to discontinue use.
3Patient Review
8/14/2013
Suprax for Urinary Tract Infection
Though this did clear my UTI, the severe diarrhea, gas, and stomach pain it caused was not worth it. I had to go see a specialist after just five days because the effects were so terrible.
3Patient Review
8/29/2012
Suprax for Acute Infection of the Nose, Throat or Sinus
I unfortunately had a really severe reaction in the form of a rash.
2.7Patient Review
10/30/2015
Suprax for Bronchitis
I had some initial bloating and gas, but after a few days started experiencing severe lower abdominal pain and diarrhea. It was really uncomfortable and I wouldn't recommend it to anyone.
2.3Patient Review
5/18/2014
Suprax for Urinary Tract Infection
I was prescribed this medicine for my first UTI. My teenage daughter once took it for a sinus infection and bronchitis and had so much stomach pain she had to stop at day 3. I was open minded about taking the medicine but I had awful gas, stomach pain and frequent stools. I stopped on day 5 for 2 days and restarted for 1 more day and was in so much awful abdominal pain I stopped the medicine. I did not finish the 10 day dose.
2.3Patient Review
2/17/2015
Suprax for Acute Sinus Infection caused by Haemophilus Parainfluenzae
Unfortunately, this didn't work for me. I had to go back multiple times and try different prescriptions, but nothing alleviated the pain I was experiencing.
1Patient Review
12/14/2011
Suprax for Bronchitis
1Patient Review
4/4/2013
Suprax for Strep Throat
I completed a 10 day dose of 400mg and soon developed an incredibly annoying salty mouth.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about suprax

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is Suprax used to treat?

"The drug SUPRAX is effective in treating urinary tract infections in adults and children six months or older who have uncomplicated infections caused by certain strains of Escherichia coli and Proteus mirabilis."

Answered by AI

What type of antibiotic is Suprax?

"It will not work for viral infections (such as common cold, flu). Using any antibiotic when it is not needed can cause it to not work for future infections.

This medication is an antibiotic that belongs to a class of drugs called cephalosporins. It works by stopping the growth of bacteria. This antibiotic only treats bacterial infections and will not work for viral infections (such as the common cold or flu). Taking antibiotics when they are not needed can make them less effective for treating future infections."

Answered by AI

Is Suprax the same as amoxicillin?

"Both antibiotics work by killing bacteria or preventing their growth.

Suprax (cefixime) and amoxicillin are two different types of antibiotics used to treat various infections caused by bacteria. Suprax is a cephalosporin antibiotic while amoxicillin is a penicillin-type antibiotic. Both antibiotics work bacteria by either killing them or preventing their growth."

Answered by AI

Is Suprax a strong antibiotic?

"Cefixime (Suprax) is an antibiotic used to treat various types of infections. It is sometimes more effective than other cephalosporin antibiotics against certain resistant bacteria. However, there are other antibiotics that can treat more types of infections, or more serious infections."

Answered by AI

Clinical Trials for Suprax

Image of Children's Healthcare of Atlanta in Atlanta, United States.

Antibiotic Strategies for Pneumonia in Children

12 - 71
All Sexes
Atlanta, GA
The goal of this clinical trial is to determine if a "watch and wait" antibiotic strategy, called Safety Net Antibiotic Prescribing (SNAP), can safely reduce unnecessary antibiotic use while ensuring that children diagnosed with community-acquired pneumonia get better from their illness. The main aims of this study are: * To compare the effectiveness of SNAP versus immediate antibiotic prescribing in children with mild community-acquired pneumonia (CAP) * To identify which patient groups benefit most from the SNAP strategy * To identify factors that shape implementation of each prescribing strategy. Researchers will compare the SNAP strategy (where parents or guardians are instructed to give antibiotics only if their child is not improving after 72 hours, or sooner if they are worsening) to the immediate antibiotic prescribing strategy (where parents or guardians are instructed to give the antibiotics right after their healthcare visit) to see if one strategy is more effective than the other. Participants will be randomly assigned to either the immediate antibiotic group or the SNAP group at enrollment. Participation lasts 14 days with follow-up surveys at 4, 7, and 14 days after enrollment.
Recruiting
Has No Placebo
Children's Healthcare of Atlanta (+3 Sites)Todd Florin, MD, MSCE
Have you considered Suprax clinical trials? We made a collection of clinical trials featuring Suprax, we think they might fit your search criteria.Go to Trials
Image of National Institutes of Health Clinical Center in Bethesda, United States.

Immune Response Study for Tick Bites

18 - 99
All Sexes
Bethesda, MD
Background: Each year, the number of cases of tick-borne diseases increases. The deer tick (Ixodes scapularis) is the vector of at least 7 pathogens that cause human diseases, including Lyme disease. Researchers want to learn more to help them develop vaccines against ticks in the future. Objective: To learn how people s bodies, particularly the skin, respond to tick bites. Eligibility: Healthy adults aged 18 years and older who have no known history of a tick-borne disease or tick bite exposure. Design: Participants will be screened with a medical history, physical exam, and blood tests. Participants will have 2 skin punch biopsies of healthy skin. For this, a sharp instrument will be used to remove a round plug of skin about the size of a pencil eraser. Participants will then have 10 clean laboratory-bred ticks placed at 2 different sites on their skin (20 ticks total). The ticks will be removed from the first site 1 day after placement and from the second site 2-4 days after placement. Participants will complete symptom diary cards. They will answer questions about itching at the tick feeding sites. They will give blood samples. Photos will be taken of the tick feeding sites. Skin punch biopsies will be collected at the sites of the tick bites. Participants will repeat the tick feeding procedures 2 times, each 2-8 weeks apart. For the 2nd and 3rd procedures, 10 clean laboratory-bred ticks will be placed at 1 site. The ticks will be removed 2-3 days after tick placement. They will have telephone follow-up visits after each procedure. After the final tick removal, participants will have follow-up visits in 4-6 weeks and again in 3 months. They will give blood samples and discuss how they are feeling. Participation will last about 5-7 months.
Phase 1 & 2
Recruiting
Quick Reply
National Institutes of Health Clinical CenterAdriana R Marques, M.D.
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