Suprax

Tonsillitis, Gonorrhea, Otitis Media + 12 more

Treatment

15 FDA approvals

10 Active Studies for Suprax

What is Suprax

Cefixime

The Generic name of this drug

Treatment Summary

Cefixime is an antibiotic medication in the cephalosporin family. It is designed to treat infections caused by bacteria and is more resistant to beta-lactamase enzymes than other antibiotics in its class. Cefixime works by blocking the production of a certain protein in the bacteria cell wall, which prevents the bacteria from growing and multiplying.

Suprax

is the brand name

image of different drug pills on a surface

Suprax Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Suprax

Cefixime

2004

39

Approved as Treatment by the FDA

Cefixime, also known as Suprax, is approved by the FDA for 15 uses including Sinusitis and Bronchitis .

Sinusitis

Bronchitis

Streptococcal Pharyngitis

Acute Exacerbations of Chronic Bronchitis caused by Haemophilus Influenzae

uncomplicated Gonorrhea

Acute Exacerbation of Chronic Bronchitis caused by Streptococcus Pneumoniae

Uncomplicated Urinary Tract Infections

Bacterial Sinusitis

bacterial otitis media

Tonsillitis streptococcal

Gonorrhea

Urinary tract infection

Bronchitis, Chronic

Otitis Media

Tonsillitis

Effectiveness

How Suprax Affects Patients

Cefixime is an antibiotic that belongs to the cephalosporin family, which also includes ceftriaxone and cefotaxime. Cefixime is particularly effective against bacteria that has become resistant to penicillins and some other cephalosporins because it does not get broken down by beta-lactamase enzymes. Cefixime works by stopping the bacteria from making the substances it needs to build its cell walls.

How Suprax works in the body

Cefixime is an antibiotic that works by blocking the growth of bacteria. It does this by targeting certain proteins inside the bacterial cell wall. This stops the cell from being able to form a protective wall around itself, which leads to its destruction. Cefixime may also interfere with the bacteria's ability to prevent its own destruction.

When to interrupt dosage

The measure of Suprax is predicated upon the diagnosed affliction, like bacterial rhinosinusitis, Streptococcal Pharyngitis and Tonsillitis. The amount additionally fluctuates as per the procedure of delivery (e.g. Powder, for suspension - Oral or Tablet - Oral) featured in the table below.

Condition

Dosage

Administration

Gonorrhea

, 400.0 mg, 100.0 mg, 200.0 mg, 200.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL

, Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, chewable - Oral, Tablet, chewable, Powder, for suspension, Powder, for suspension - Oral, Powder, for solution, Powder, for solution - Oral

Dysentery, Bacillary

, 400.0 mg, 100.0 mg, 200.0 mg, 200.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL

, Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, chewable - Oral, Tablet, chewable, Powder, for suspension, Powder, for suspension - Oral, Powder, for solution, Powder, for solution - Oral

Community Acquired Pneumonia (CAP)

, 400.0 mg, 100.0 mg, 200.0 mg, 200.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL

, Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, chewable - Oral, Tablet, chewable, Powder, for suspension, Powder, for suspension - Oral, Powder, for solution, Powder, for solution - Oral

Bronchitis

, 400.0 mg, 100.0 mg, 200.0 mg, 200.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL

, Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, chewable - Oral, Tablet, chewable, Powder, for suspension, Powder, for suspension - Oral, Powder, for solution, Powder, for solution - Oral

Tonsillitis

, 400.0 mg, 100.0 mg, 200.0 mg, 200.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL

, Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, chewable - Oral, Tablet, chewable, Powder, for suspension, Powder, for suspension - Oral, Powder, for solution, Powder, for solution - Oral

Gonorrhea

, 400.0 mg, 100.0 mg, 200.0 mg, 200.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL

, Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, chewable - Oral, Tablet, chewable, Powder, for suspension, Powder, for suspension - Oral, Powder, for solution, Powder, for solution - Oral

Urinary tract infection

, 400.0 mg, 100.0 mg, 200.0 mg, 200.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL

, Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, chewable - Oral, Tablet, chewable, Powder, for suspension, Powder, for suspension - Oral, Powder, for solution, Powder, for solution - Oral

Otitis Media

, 400.0 mg, 100.0 mg, 200.0 mg, 200.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL

, Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, chewable - Oral, Tablet, chewable, Powder, for suspension, Powder, for suspension - Oral, Powder, for solution, Powder, for solution - Oral

Lyme Disease

, 400.0 mg, 100.0 mg, 200.0 mg, 200.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL

, Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, chewable - Oral, Tablet, chewable, Powder, for suspension, Powder, for suspension - Oral, Powder, for solution, Powder, for solution - Oral

Sinusitis

, 400.0 mg, 100.0 mg, 200.0 mg, 200.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL

, Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, chewable - Oral, Tablet, chewable, Powder, for suspension, Powder, for suspension - Oral, Powder, for solution, Powder, for solution - Oral

Sinusitis

, 400.0 mg, 100.0 mg, 200.0 mg, 200.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL

, Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, chewable - Oral, Tablet, chewable, Powder, for suspension, Powder, for suspension - Oral, Powder, for solution, Powder, for solution - Oral

Salmonella Infections

, 400.0 mg, 100.0 mg, 200.0 mg, 200.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL

, Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, chewable - Oral, Tablet, chewable, Powder, for suspension, Powder, for suspension - Oral, Powder, for solution, Powder, for solution - Oral

Streptococcal Pharyngitis

, 400.0 mg, 100.0 mg, 200.0 mg, 200.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL

, Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, chewable - Oral, Tablet, chewable, Powder, for suspension, Powder, for suspension - Oral, Powder, for solution, Powder, for solution - Oral

Bronchitis, Chronic

, 400.0 mg, 100.0 mg, 200.0 mg, 200.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL

, Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, chewable - Oral, Tablet, chewable, Powder, for suspension, Powder, for suspension - Oral, Powder, for solution, Powder, for solution - Oral

Disease

, 400.0 mg, 100.0 mg, 200.0 mg, 200.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL

, Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Tablet, chewable - Oral, Tablet, chewable, Powder, for suspension, Powder, for suspension - Oral, Powder, for solution, Powder, for solution - Oral

Warnings

Suprax has one contraindication and its ingestion should be avoided when suffering from any of the conditions presented in the following table.

Suprax Contraindications

Condition

Risk Level

Notes

Pulse Frequency

Do Not Combine

There are 20 known major drug interactions with Suprax.

Common Suprax Drug Interactions

Drug Name

Risk Level

Description

Vibrio cholerae CVD 103-HgR strain live antigen

Major

The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Cefixime.

Abciximab

Minor

The therapeutic efficacy of Abciximab can be decreased when used in combination with Cefixime.

Alteplase

Minor

The therapeutic efficacy of Alteplase can be decreased when used in combination with Cefixime.

Amediplase

Minor

The therapeutic efficacy of Amediplase can be decreased when used in combination with Cefixime.

Ancrod

Minor

The therapeutic efficacy of Ancrod can be decreased when used in combination with Cefixime.

Suprax Toxicity & Overdose Risk

Overdosing on ibuprofen can result in symptoms such as bloody urine, diarrhea, nausea, stomach pain, and vomiting.

image of a doctor in a lab doing drug, clinical research

Suprax Novel Uses: Which Conditions Have a Clinical Trial Featuring Suprax?

11 active studies are presently investigating the potential of Suprax to treat Acute Exacerbations of Chronic Bronchitis caused by Streptococcus Pneumoniae, Bacterial Rhinosinusitis and Tonsillitis.

Condition

Clinical Trials

Trial Phases

Gonorrhea

0 Actively Recruiting

Bronchitis, Chronic

0 Actively Recruiting

Tonsillitis

0 Actively Recruiting

Urinary tract infection

0 Actively Recruiting

Community Acquired Pneumonia (CAP)

5 Actively Recruiting

Not Applicable, Phase 1, Phase 3

Dysentery, Bacillary

0 Actively Recruiting

Bronchitis

0 Actively Recruiting

Sinusitis

0 Actively Recruiting

Gonorrhea

0 Actively Recruiting

Salmonella Infections

0 Actively Recruiting

Streptococcal Pharyngitis

0 Actively Recruiting

Sinusitis

0 Actively Recruiting

Disease

0 Actively Recruiting

Lyme Disease

3 Actively Recruiting

Phase 1, Phase 2, Phase 3, Not Applicable

Otitis Media

0 Actively Recruiting

Suprax Reviews: What are patients saying about Suprax?

5

Patient Review

2/3/2012

Suprax for Bronchitis

I'm a 65-year-old man who caught a throat, nose, and sinus infection from my 22-month-old grandson. I started feeling better after only two days and was able to go back to work after two more. The only side effect was terrible gas.

4.7

Patient Review

9/4/2014

Suprax for Urinary Tract Infection

Suprax is great for UTIs and doesn't make me incredibly nauseous like other drugs have in the past. However, it is on the expensive side and pharmacies don't always keep it in stock. So, if you're thinking of using this medication be aware that you may have to wait a few days for it to be ordered.

4.3

Patient Review

1/8/2012

Suprax for Acute Infection of the Nose, Throat or Sinus

I've taken a variety of antibiotics over the years, and this was by far the WORST. The uncontrollable diarrhea made it really tough to leave the house; on top of that, it caused a yeast infection which took weeks to recover from. If you can help it, steer clear of this one.

3.7

Patient Review

10/30/2013

Suprax for Infection of the Middle Ear by H. Influenzae Bacteria

Worked to clear my uti but caused TERRIBLE diarrhea, gas and stomach pain. I've been off it for over a week and the diarrhea still won't stop. Now I have to go to a gastroenterologist to be checked out for C. Diff. So after paying $100 for 5 pills of this poison now I'm going to have to shell out even more money to see a gastro specialist.

3

Patient Review

3/13/2012

Suprax for Urinary Tract Infection

Suprax was given to my 2 year old son, and it's the only thing that ever worked for him.

3

Patient Review

4/12/2012

Suprax for Middle Ear Infection

I experienced improvement for the first few days, but then on day four I started having terrible stomach cramps which led to intense diarrhea. I had to discontinue use.

3

Patient Review

8/14/2013

Suprax for Urinary Tract Infection

Though this did clear my UTI, the severe diarrhea, gas, and stomach pain it caused was not worth it. I had to go see a specialist after just five days because the effects were so terrible.

3

Patient Review

8/29/2012

Suprax for Acute Infection of the Nose, Throat or Sinus

I unfortunately had a really severe reaction in the form of a rash.

2.7

Patient Review

10/30/2015

Suprax for Bronchitis

I had some initial bloating and gas, but after a few days started experiencing severe lower abdominal pain and diarrhea. It was really uncomfortable and I wouldn't recommend it to anyone.

2.3

Patient Review

5/18/2014

Suprax for Urinary Tract Infection

I was prescribed this medicine for my first UTI. My teenage daughter once took it for a sinus infection and bronchitis and had so much stomach pain she had to stop at day 3. I was open minded about taking the medicine but I had awful gas, stomach pain and frequent stools. I stopped on day 5 for 2 days and restarted for 1 more day and was in so much awful abdominal pain I stopped the medicine. I did not finish the 10 day dose.

2.3

Patient Review

2/17/2015

Suprax for Acute Sinus Infection caused by Haemophilus Parainfluenzae

Unfortunately, this didn't work for me. I had to go back multiple times and try different prescriptions, but nothing alleviated the pain I was experiencing.

1

Patient Review

12/14/2011

Suprax for Bronchitis

1

Patient Review

4/4/2013

Suprax for Strep Throat

I completed a 10 day dose of 400mg and soon developed an incredibly annoying salty mouth.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about suprax

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is Suprax used to treat?

"The drug SUPRAX is effective in treating urinary tract infections in adults and children six months or older who have uncomplicated infections caused by certain strains of Escherichia coli and Proteus mirabilis."

Answered by AI

What type of antibiotic is Suprax?

"It will not work for viral infections (such as common cold, flu). Using any antibiotic when it is not needed can cause it to not work for future infections.

This medication is an antibiotic that belongs to a class of drugs called cephalosporins. It works by stopping the growth of bacteria. This antibiotic only treats bacterial infections and will not work for viral infections (such as the common cold or flu). Taking antibiotics when they are not needed can make them less effective for treating future infections."

Answered by AI

Is Suprax the same as amoxicillin?

"Both antibiotics work by killing bacteria or preventing their growth.

Suprax (cefixime) and amoxicillin are two different types of antibiotics used to treat various infections caused by bacteria. Suprax is a cephalosporin antibiotic while amoxicillin is a penicillin-type antibiotic. Both antibiotics work bacteria by either killing them or preventing their growth."

Answered by AI

Is Suprax a strong antibiotic?

"Cefixime (Suprax) is an antibiotic used to treat various types of infections. It is sometimes more effective than other cephalosporin antibiotics against certain resistant bacteria. However, there are other antibiotics that can treat more types of infections, or more serious infections."

Answered by AI

Clinical Trials for Suprax

Image of Northern Light Eastern Maine Medical Center in Bangor, United States.

VLA15 Vaccine for Lyme Disease

Any Age
All Sexes
Bangor, ME

The purpose of this study is to learn about the safety effects of the Lyme disease vaccine (called VLA15), and its ability to protect people from Lyme disease after a 5th dose of the vaccine. This study is seeking participants who: * are generally healthy and 7 years of age and older, * have already been vaccinated with 4 doses of VLA15 (from the VALOR study), and have blood sample taken post dose 4. * are not currently taking, or haven't recently taken, medicines like chemotherapy, blood products, or blood thinners. * are not pregnant or breastfeeding and do not plan to become pregnant while receiving the study vaccine. All participants in this study will receive a total of 1 dose through a shot in the upper arm, either VLA15 or saline shot (saltwater). The study will compare the experiences of people receiving the study vaccine or saltwater shot. Participants will take part in this study for about 12 months. During this time, they will have 4 planned clinic visits. The clinic visits may include having a health check, giving a small amount of blood and getting the study vaccine or saltwater as a shot at the first visit.

Phase 3
Recruiting

Northern Light Eastern Maine Medical Center (+21 Sites)

Pfizer CT.gov Call Center

Pfizer

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Image of Children's Healthcare of Atlanta in Atlanta, United States.

Antibiotic Strategies for Pneumonia in Children

12 - 71
All Sexes
Atlanta, GA

The goal of this clinical trial is to determine if a "watch and wait" antibiotic strategy, called Safety Net Antibiotic Prescribing (SNAP), can safely reduce unnecessary antibiotic use while ensuring that children diagnosed with community-acquired pneumonia get better from their illness. The main aims of this study are: * To compare the effectiveness of SNAP versus immediate antibiotic prescribing in children with mild community-acquired pneumonia (CAP) * To identify which patient groups benefit most from the SNAP strategy * To identify factors that shape implementation of each prescribing strategy. Researchers will compare the SNAP strategy (where parents or guardians are instructed to give antibiotics only if their child is not improving after 72 hours, or sooner if they are worsening) to the immediate antibiotic prescribing strategy (where parents or guardians are instructed to give the antibiotics right after their healthcare visit) to see if one strategy is more effective than the other. Participants will be randomly assigned to either the immediate antibiotic group or the SNAP group at enrollment. Participation lasts 14 days with follow-up surveys at 4, 7, and 14 days after enrollment.

Recruiting
Has No Placebo

Children's Healthcare of Atlanta (+3 Sites)

Todd Florin, MD, MSCE

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