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What is Sprix
KetorolacThe Generic name of this drug
Treatment SummaryKetorolac is a type of medication used to reduce pain by reducing inflammation. It is available in the form of an oral tablet, injectable, nasal spray, and ophthalmic solution. It can be used to treat a variety of painful conditions, including postoperative pain, arthritis, menstrual disorders, headaches, and back pain. In some cases, it can be used as an alternative to opioids such as morphine and meperidine for pain management.
Toradolis the brand name
Sprix Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Toradol
Ketorolac
1991
316
Approved as Treatment by the FDA
Ketorolac, also called Toradol, is approved by the FDA for 2 uses like induction of Nerve Block and caudal epidural block therapy .induction of Nerve Block
Used to treat induction of Nerve Block in combination with Bupivacaine
caudal epidural block therapy
Used to treat caudal epidural block therapy in combination with Bupivacaine
Effectiveness
How Sprix Affects PatientsKetorolac is a type of non-selective painkiller that blocks two enzymes (COX-1 and COX-2). The COX-1 enzyme is always active and can be found in the platelets, stomach lining, and blood vessel walls. The COX-2 enzyme is only active when inflammation, pain, or fever is present. When COX-1 is blocked, it leads to an increased risk of bleeding and stomach ulcers. The desired effects of the drug like reducing inflammation and pain come from blocking the COX-2 enzyme. Taking ketorolac long-term can lead to serious
How Sprix works in the bodyKetorolac works to reduce pain and inflammation in the body by blocking pathways that produce prostaglandins. Prostaglandins are molecules involved in inflammation and pain, and ketorolac works by stopping the enzymes that create them. The drug is a mixture of two molecules, but the active ingredient is responsible for its pain-relieving and anti-inflammatory effects.
When to interrupt dosage
The measure of Sprix is contingent upon the identified condition, for instance Eye, Macular Edema, Cystoid and Pericarditis Acute. The quantity of dosage is contingent on the approach of delivery (e.g. Tablet - Oral or Ophthalmic) referenced in the table underneath.Condition
Dosage
Administration
Cataract Surgery
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
acute, moderate Pain
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Intraocular Lens Replacement
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Eye
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Eye Pain
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Inflammation
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
corneal refractive surgery
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Induced Hyperthermia
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Macular Edema, Cystoid
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Miosis disorder
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
caudal epidural block therapy
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Macular Edema, Cystoid
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Seasonal Allergic Conjunctivitis
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Ocular Itching
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Acute Coryza
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Macular Edema, Cystoid
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Local Anaesthesia therapy
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Pupil
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
postoperative ocular pain
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
induction of Nerve Block
, 5.0 mg/mL, 4.5 mg/mL, 15.0 mg/mL, 30.0 mg/mL, 10.0 mg, 15.75 mg, 4.0 mg/mL, 5.0 mg, 60.0 mg/mL, 0.5 %, 0.4 %, 0.45 %, 2.88 mg/mL, 0.4 mg/mL, 40.0 mg/mL, 3.0 mg/mL, 9.0 mg/mL, 50.0 mg/mL, 45.0 mg/mL, 0.5 mg/mL, 10.0 mg/mL
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Intramuscular; Intravenous, Injection, Injection - Intramuscular; Intravenous, Oral, Tablet, film coated, Tablet, film coated - Oral, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection - Intramuscular, Tablet, Tablet - Oral, Solution, Solution - Ophthalmic, Injection, solution, Injection, solution - Intramuscular; Intravenous, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Intraocular, Injection, solution, concentrate, Injection, solution, concentrate - Intraocular, Kit - Epidural; Infiltration; Intramuscular; Intravenous, Kit, Epidural; Infiltration; Intramuscular; Intravenous, Infiltration; Intramuscular; Intravenous; Topical, Kit - Infiltration; Intramuscular; Intravenous; Topical, Injection, solution - Ophthalmic, Injection, solution - Intraocular, Epidural; Infiltration; Intramuscular; Intravenous; Topical, Kit - Epidural; Infiltration; Intramuscular; Intravenous; Topical, Topical, Spray, metered - Topical, Solution, concentrate, Solution, concentrate - Intraocular; Irrigation, Intraocular; Irrigation, Kit - Ophthalmic
Warnings
Sprix has twenty-eight contraindications, thus it should not be administered if any of the conditions outlined in the following table exist.Sprix ContraindicationsCondition
Risk Level
Notes
Heart failure
Do Not Combine
Hyperkalemia
Do Not Combine
Renal Insufficiency
Do Not Combine
Hemorrhagic Disorders
Do Not Combine
Kidney Failure
Do Not Combine
A History of Gastric or Duodenal Ulcers
Do Not Combine
active liver disease
Do Not Combine
Major Surgery
Do Not Combine
Pulse Frequency
Do Not Combine
Gastrointestinal Hemorrhage
Do Not Combine
Crohn's Disease
Do Not Combine
suspected cerebrovascular bleeding
Do Not Combine
active Gastrointestinal Bleeding
Do Not Combine
NSAID-Induced Asthma
Do Not Combine
Severe Hepatic Impairment
Do Not Combine
incomplete hemostasis
Do Not Combine
Coronary Artery Bypass Grafting
Do Not Combine
Gastrointestinal Perforation
Do Not Combine
Pulse Frequency
Do Not Combine
Hemorrhage
Do Not Combine
Peptic Ulcer
Do Not Combine
Pulse Frequency
Do Not Combine
Labour
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Third trimester of pregnancy
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Ketorolac may interact with Pulse Frequency
Severe Hypersensitivity Reactions
Do Not Combine
Ketorolac may interact with Pulse Frequency
Common Sprix Drug Interactions
Drug Name
Risk Level
Description
Aceclofenac
Major
The risk or severity of adverse effects can be increased when Ketorolac is combined with Aceclofenac.
Acemetacin
Major
The risk or severity of adverse effects can be increased when Ketorolac is combined with Acemetacin.
Acetylsalicylic acid
Major
The risk or severity of adverse effects can be increased when Ketorolac is combined with Acetylsalicylic acid.
Alclofenac
Major
The risk or severity of adverse effects can be increased when Ketorolac is combined with Alclofenac.
Alminoprofen
Major
The risk or severity of adverse effects can be increased when Ketorolac is combined with Alminoprofen.
Sprix Toxicity & Overdose RiskTaking ketorolac can lead to side effects such as abdominal pain, indigestion, nausea, headaches, and fatigue in up to 39% of patients. An overdose can cause symptoms such as nausea, vomiting, upper abdominal pain, gastrointestinal bleeding, fatigue, and drowsiness. More severe effects such as high blood pressure, kidney damage or failure, hypoventilation, or coma may also occur in rare cases. Pregnant women should avoid ketorolac after 30 weeks gestation since it increases the risk of fetal ductus arteriosus closure. Women who are trying to conceive are also advised not to take ket
Sprix Novel Uses: Which Conditions Have a Clinical Trial Featuring Sprix?
188 active trials are being conducted to analyze the potential of Sprix in providing relief from Macular Edema, Cystoid, acute, moderate Pain and for Intraocular Lens Replacement.Condition
Clinical Trials
Trial Phases
Inflammation
171 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Early Phase 1, Phase 3, Phase 4
induction of Local Anaesthesia
0 Actively Recruiting
Macular Edema, Cystoid
0 Actively Recruiting
Eye
0 Actively Recruiting
postoperative ocular pain
0 Actively Recruiting
caudal epidural block therapy
4 Actively Recruiting
Not Applicable
Ocular Itching
0 Actively Recruiting
Miosis disorder
0 Actively Recruiting
Cataract Surgery
1 Actively Recruiting
Phase 4
corneal refractive surgery
0 Actively Recruiting
Pupil
0 Actively Recruiting
Pericarditis Acute
0 Actively Recruiting
Macular Edema, Cystoid
0 Actively Recruiting
acute, moderate Pain
0 Actively Recruiting
Pain
0 Actively Recruiting
Eye Pain
2 Actively Recruiting
Not Applicable, Phase 4
Acute Coryza
0 Actively Recruiting
Induced Hyperthermia
0 Actively Recruiting
induction of Nerve Block
0 Actively Recruiting
Macular Edema, Cystoid
1 Actively Recruiting
Phase 1, Phase 2
Sprix Reviews: What are patients saying about Sprix?
5Patient Review
6/19/2020 Despite the burning sensation that comes with this spray, it's an amazing drug. Toradol is a true miracle worker.
5Patient Review
5/30/2019 This medication, in conjunction with Percocet, was prescribed to me for managing pain after ankle surgery. I never had to fill the Percocet script because the nasal spray worked so well. My surgeon was amazed at how good I looked just three days post-op.
5Patient Review
12/8/2020 I'm so glad that there are non-narcotic pain relievers available that actually work! The downside is that they're quite expensive and not always easy to fill at a pharmacy.
5Patient Review
9/2/2020 This drug has been a total game-changer for me. I'm now five years sober from opiates, and while it does still burn, the pain relief is well worth it!
4.7Patient Review
8/7/2018 This drug is really effective at removing pain. I can't take it every day, but when I do use it, it takes away the pain much better than Norco does. The only downside is that inhaling it burns really badly.
4.7Patient Review
6/15/2020 This provided great pain relief after my outpatient procedure. The nose pain was gone almost instantly. However, it tastes really bad, so make sure you don't inhale it!
3.7Patient Review
3/26/2020 Sprix is effective in pain relief, but unfortunately leaves the inside of my nose feeling raw and painful. I'm still pretty pleased overall, though.
3.7Patient Review
12/15/2020 I'm not sure why everyone is complaining about the spray burning so much. Maybe they're not doing it right? You're not supposed to sniff the spray up your nose after you use it; it's supposed to sit in your nostril. If you do that (the correct way) it only burns a little bit for a few seconds. The only problem I had was that it made me sneeze after and caused my nose to run, which probably decreased some of the effectiveness. I did get some pain relief from this though.
3.7Patient Review
10/30/2020 Sprix was prescribed to me by my doctor and it did help with the pain, though you have to be careful as NSAIDS can lead to other medical conditions. I started getting headaches after taking this medication and was recently diagnosed with bleeding on my brain.
3.7Patient Review
5/7/2021 Sprix is an amazing medication for menstrual cramps, as it is a strong analgesic. Even though it burns when sprayed (I follow the directions), it's worth it to me to avoid cramps all day.
1.7Patient Review
2/19/2020 The burning sensation I felt was really intense, like I had just sprayed battery acid into my nose.
1.3Patient Review
3/17/2020 The burning sensation wasn't too bad, but I became nauseous when the medication ran down my throat.
1Patient Review
3/25/2019 Not only was this treatment ineffective, but it also caused a lot of pain when I swallowed it.
1Patient Review
12/5/2018 This product didn't work for me at all. Not only did it not stop the pain, but it also caused a burning sensation in my nose and throat that lasted for about 30-40 minutes after each dose. I tried it a third time and ended up with a nosebleed. Overall, this was a very unpleasant experience and I'll be sticking to naproxen from now on.
1Patient Review
1/6/2019 This was a terrible experience. The burning sensation was unbearable. I would never take this drug again.
1Patient Review
8/16/2019 Unfortunately, this medication did not work at all for my rheumatoid arthritis pain. If anything, it made the pain in my testicles worse.
1Patient Review
5/6/2019 Unfortunately, this medication didn't provide the relief I was hoping for. If anything, it made my symptoms worse. Will not be trying again.
1Patient Review
3/15/2019 This medication created a burning sensation that was unbearable. Additionally, it gave me really bad allergies and made me feel lightheaded and out of it.
Patient Q&A Section about sprix
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.How long does it take for SPRIX to work?
"Ketorolac nasal spray (Sprix) starts working to relieve pain in as little as 20 to 30 minutes for some people."
Answered by AI
What is SPRIX medication?
"SPRIX should be used for the short-term management (5 days or less) of moderate to moderately severe pain that requires an opioid level of analgesia."
Answered by AI
Does SPRIX make you drowsy?
"You may feel briefly uncomfortable if you use this medication. You may also feel nauseous, dizzy, or tired. If you feel any of these effects for an extended period of time, please tell your doctor."
Answered by AI
What is SPRIX used for?
"Sprix is a medication used to manage moderate to moderately severe pain for a maximum of 5 days. It is classified as an opioid medication."
Answered by AI