Spiriva

Acute Bronchitis, Asthma, Emphysema + 4 more
Treatment
20 Active Studies for Spiriva

What is Spiriva

TiotropiumThe Generic name of this drug
Treatment SummaryTiotropium is a long-acting medication used to help with breathing difficulties caused by chronic obstructive pulmonary disease (COPD) and asthma. It works by relaxing the muscles in the airways, allowing air to flow more freely. Tiotropium is more specific for the type of muscarinic receptors found in the lungs than other similar medications. It was approved by the FDA in 2004.
Spirivais the brand name
Spiriva Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Spiriva
Tiotropium
2004
8

Effectiveness

How Spiriva Affects PatientsTiotropium is an antimuscarinic drug that helps to widen the airways in the lungs and make breathing easier. The effects of this drug can last up to a day, and it is generally considered safe even if taken in higher amounts than recommended.
How Spiriva works in the bodyTiotropium is a drug that relaxes the muscles in the lungs, allowing them to expand and resulting in easier breathing. It works by blocking certain receptors in the lungs, called muscarinic receptors, which are responsible for muscle contraction.

When to interrupt dosage

The suggested dosage of Spiriva is contingent upon the recognized condition, including Chronic Bronchitis, Bronchoconstriction and Acute Bronchitis. The dose also fluctuates according to the technique of delivery (e.g. Respiratory (inhalation) or Spray, metered) as enumerated in the table below.
Condition
Dosage
Administration
Acute Bronchitis
0.018 mg, , 0.003124 mg, 0.001562 mg, 0.0025 mg, 0.0025 mg/pump actuation
, Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation), Solution, Solution - Respiratory (inhalation), Spray, metered, Spray, metered - Respiratory (inhalation), Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation)
Emphysema
0.018 mg, , 0.003124 mg, 0.001562 mg, 0.0025 mg, 0.0025 mg/pump actuation
, Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation), Solution, Solution - Respiratory (inhalation), Spray, metered, Spray, metered - Respiratory (inhalation), Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation)
Chronic Obstructive Airway Disease
0.018 mg, , 0.003124 mg, 0.001562 mg, 0.0025 mg, 0.0025 mg/pump actuation
, Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation), Solution, Solution - Respiratory (inhalation), Spray, metered, Spray, metered - Respiratory (inhalation), Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation)
Asthma
0.018 mg, , 0.003124 mg, 0.001562 mg, 0.0025 mg, 0.0025 mg/pump actuation
, Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation), Solution, Solution - Respiratory (inhalation), Spray, metered, Spray, metered - Respiratory (inhalation), Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation)
Bronchoconstriction
0.018 mg, , 0.003124 mg, 0.001562 mg, 0.0025 mg, 0.0025 mg/pump actuation
, Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation), Solution, Solution - Respiratory (inhalation), Spray, metered, Spray, metered - Respiratory (inhalation), Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation)
Bronchitis, Chronic
0.018 mg, , 0.003124 mg, 0.001562 mg, 0.0025 mg, 0.0025 mg/pump actuation
, Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation), Solution, Solution - Respiratory (inhalation), Spray, metered, Spray, metered - Respiratory (inhalation), Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation)
Chronic Obstructive Pulmonary Disease
0.018 mg, , 0.003124 mg, 0.001562 mg, 0.0025 mg, 0.0025 mg/pump actuation
, Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation), Solution, Solution - Respiratory (inhalation), Spray, metered, Spray, metered - Respiratory (inhalation), Oral; Respiratory (inhalation), Capsule - Oral; Respiratory (inhalation)

Warnings

Spiriva has two contraindications and should not be taken in combination with the conditions shown in the table below.Spiriva Contraindications
Condition
Risk Level
Notes
Not being treated with an inhaled corticosteroid
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Tiotropium may interact with Pulse Frequency
There are 20 known major drug interactions with Spiriva.
Common Spiriva Drug Interactions
Drug Name
Risk Level
Description
Aclidinium
Major
The risk or severity of adverse effects can be increased when Tiotropium is combined with Aclidinium.
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Tiotropium.
Cimetropium
Major
The risk or severity of adverse effects can be increased when Tiotropium is combined with Cimetropium.
Clomipramine
Major
The metabolism of Clomipramine can be decreased when combined with Tiotropium.
Clonidine
Major
The metabolism of Clonidine can be decreased when combined with Tiotropium.
Spiriva Toxicity & Overdose RiskTaking too much tiotropium may cause mental confusion, shaking, abdominal pain, and extreme constipation. However, doses up to 282µg have not been found to cause any anticholinergic effects in a test group of 6 patients. If someone has overdosed on tiotropium, they should stop taking it and receive supportive care.
image of a doctor in a lab doing drug, clinical research

Spiriva Novel Uses: Which Conditions Have a Clinical Trial Featuring Spiriva?

280 active clinical trials are assessing the potential of Spiriva to alleviate Asthma, Bronchoconstriction and Chronic Obstructive Pulmonary Disease (COPD).
Condition
Clinical Trials
Trial Phases
Chronic Obstructive Pulmonary Disease
85 Actively Recruiting
Phase 3, Not Applicable, Phase 1, Phase 2, Early Phase 1, Phase 4
Asthma
88 Actively Recruiting
Phase 4, Early Phase 1, Phase 2, Not Applicable, Phase 1, Phase 3
Bronchoconstriction
0 Actively Recruiting
Chronic Obstructive Airway Disease
6 Actively Recruiting
Not Applicable, Phase 4
Acute Bronchitis
1 Actively Recruiting
Not Applicable
Bronchitis, Chronic
0 Actively Recruiting
Emphysema
4 Actively Recruiting
Phase 2, Not Applicable

Spiriva Reviews: What are patients saying about Spiriva?

5Patient Review
11/22/2016
Spiriva for Bronchospasm Prevention with COPD
This medication has helped me a lot with my breathing. Ventolin is still necessary but it's great to have some help. I hope that eventually I won't need the rescue inhaler at all.
5Patient Review
5/27/2020
Spiriva for Prevention of Bronchospasms with Emphysema
This drug has been an absolute godsend. I was struggling to do even simple household tasks before, and now I feel like I can live a normal life again.
5Patient Review
7/15/2022
Spiriva for Prevention of Bronchospasms with Emphysema
Within just three days of using this medication, I have already noticed a significant difference in my breathing. I used to have to use an inhaler multiple times a day, but now I only need it once in the morning. This has truly been life-changing for me!
5Patient Review
4/30/2019
Spiriva for Bronchospasm Prevention with COPD
The last two refills of this prescription have had a very strong soapy taste and smell upon inhalation.
5Patient Review
7/15/2022
Spiriva for Prevention of Bronchospasms with Emphysema
I've only been using this medication for a short time, but I'm already noticing significant improvement in my breathing. I used to have to use an inhaler several times throughout the day, but now I can go all day without feeling breathless. This has made a huge difference in my quality of life.
View All Reviews
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about spiriva

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the difference between Symbicort and Spiriva?

"The first medication, Spiriva Inhalation Powder, is from the anticholinergic drug class. The second medication, Symbicort, is a combination of a steroid and a long-acting bronchodilator."

Answered by AI

What is the difference between albuterol and Spiriva?

"The drug Spiriva (Tiotropium) makes it easier to breathe. The drug ProAir HFA (albuterol) acts quickly to stop asthma attacks and help you breathe easier. However, ProAir HFA is not used for long-term treatment and prevention of asthma since its effects don't last long."

Answered by AI

What is the drug Spiriva used for?

"SPIRIVA RESPIMAT is a long-term, once-daily prescription maintenance medicine used to control symptoms of chronic obstructive pulmonary disease (COPD) by relaxing your airways and keeping them open. COPD includes chronic bronchitis and emphysema."

Answered by AI

Is Spiriva inhaler a steroid?

"SPIRIVA RESPIMAT is a non-steroidal inhaler that has shown to be effective and safe for patients aged 6 and up in clinical trials."

Answered by AI

Is Spiriva for asthma or COPD?

"Spiriva is a drug that helps to relax smooth muscles in the lungs by a different mechanism than long-acting beta-agonists such as Serevent. It is approved for treatment of COPD (chronic obstructive pulmonary disease) but not for asthma."

Answered by AI

What inhaler is the same as Spiriva?

"What's an inhaler that works like Spiriva? Tudorza pressair (aclidinium) and Seebri Neohaler (glycopyrrolate) are similar to Spiriva and Incruse Ellipta."

Answered by AI

Clinical Trials for Spiriva

Have you considered Spiriva clinical trials? We made a collection of clinical trials featuring Spiriva, we think they might fit your search criteria.
Have you considered Spiriva clinical trials? We made a collection of clinical trials featuring Spiriva, we think they might fit your search criteria.
Have you considered Spiriva clinical trials? We made a collection of clinical trials featuring Spiriva, we think they might fit your search criteria.
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