Hypofractionated Radiation Therapy for Endometrial Cancer

Phase-Based Progress Estimates
Huntsman Cancer Institute/University of Utah, Salt Lake City, UTEndometrial Cancer+1 MoreHypofractionated Radiation Therapy - Radiation
What conditions do you have?

Study Summary

This trial is testing whether delivering more radiation over a shorter time period is more effective in treating cervical or endometrial cancer with fewer side effects.

Eligible Conditions
  • Cervical Cancer
  • Endometrial Cancer

Treatment Effectiveness

Study Objectives

3 Primary · 10 Secondary · Reporting Duration: At week 3 and 1 year

At week 3
Score of Decision Regret Scale
Year 1
Decision Regret Scale- summary score
Baseline to week 3
Change in Functional Assessment of Cancer Therapy-Cervix
Change in financial toxicity
Change in gastrointestional toxicities
Year 1
Change in COST-FACIT Measure of Financial Toxicity
Change in Functional Assessment of Cancer Therapy-Cervix (FACT-Cx)
Change in gastrointestinal toxicities as collected through Patient-Reported Outcomes instruments (PRO-CTCAE)
Change in urinary domain of the Expanded Prostate Cancer Index Composite (EPIC) instrument
Week 3
Change in toxicity
Year 3
Overall survival
Up to 3 years
Ability to administer clinical trial to evaluate hypofractionated radiotherapy

Trial Safety

Trial Design

1 Treatment Group

Treatment (hypo-fractionated radiotherapy)
1 of 1

Experimental Treatment

64 Total Participants · 1 Treatment Group

Primary Treatment: Hypofractionated Radiation Therapy · No Placebo Group · N/A

Treatment (hypo-fractionated radiotherapy)
Experimental Group · 1 Intervention: Hypofractionated Radiation Therapy · Intervention Types: Radiation
First Studied
Drug Approval Stage
How many patients have taken this drug
Hypofractionated Radiation Therapy
Completed Phase 2

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: at week 3 and 1 year

Who is running the clinical trial?

National Cancer Institute (NCI)NIH
13,153 Previous Clinical Trials
41,162,568 Total Patients Enrolled
71 Trials studying Endometrial Cancer
70,527 Patients Enrolled for Endometrial Cancer
University of UtahLead Sponsor
1,008 Previous Clinical Trials
1,787,318 Total Patients Enrolled
2 Trials studying Endometrial Cancer
15 Patients Enrolled for Endometrial Cancer
Gita Suneja, MDPrincipal InvestigatorHuntsman Cancer Institute/ University of Utah

Eligibility Criteria

Age 18+ · Female Participants · 9 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You are expected to live for at least 2 more years.

Frequently Asked Questions

Are there any openings for volunteers to join this research at present?

"According to the data posted on clinicaltrials.gov, this trial is still enlisting participants. The initial posting occurred on 11th November 2021 and was last revised on 1st March 2022." - Anonymous Online Contributor

Unverified Answer

What is the sampling size of this research project?

"Affirmative. According to the clinicaltrials.gov website, enrollment is open for this experiment which was initially advertised on November 11th 2021 and last modified on March 1st 2022. 64 volunteers must be recruited from a single medical center." - Anonymous Online Contributor

Unverified Answer

What is the primary objective of this clinical trial?

"The primary purpose of this trial, which will be conducted over Baseline to week 3 of pelvic radiotherapy, is to assess the efficacy of hypofractionated radiotherapy. Auxiliary objectives include assessing financial toxicity with a Comprehensive Score for Financial Toxicity, making use of Decision Regret Scale and looking at changes in Functional Assessment of Cancer Therapy-Cervix (all using 90% confidence intervals)." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.