Solu-Medrol

Stevens-Johnson Syndrome, Pemphigus, Ophthalmia, Sympathetic + 45 more

Treatment

5 FDA approvals

20 Active Studies for Solu-Medrol

What is Solu-Medrol

Methylprednisolone hemisuccinate

The Generic name of this drug

Treatment Summary

Methylprednisolone is a type of steroid medication that is more powerful than prednisone. It was approved by the FDA in 1957 and is currently being studied as a potential treatment for COVID-19-associated pneumonia in those with weakened immune systems. Clinical trials are underway to determine the efficacy of methylprednisolone in treating this virus.

Solu-medrol

is the brand name

image of different drug pills on a surface

Solu-Medrol Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Solu-medrol

Methylprednisolone hemisuccinate

1959

89

Approved as Treatment by the FDA

Methylprednisolone hemisuccinate, also known as Solu-medrol, is approved by the FDA for 5 uses including Tuberculosis, Pulmonary and Tuberculosis, Pulmonary .

Tuberculosis, Pulmonary

Used to treat disseminated Pulmonary Tuberculosis (TB) in combination with null

Tuberculosis, Pulmonary

Used to treat fulminating Pulmonary Tuberculosis in combination with null

Tuberculous Meningitis

Used to treat Tuberculous Meningitis in combination with null

Tuberculosis, Meningeal

Used to treat Tuberculous Meningitis in combination with null

Subarachnoid Block

Used to treat Subarachnoid Block in combination with null

Effectiveness

How Solu-Medrol Affects Patients

Corticosteroids help reduce inflammation by binding to the glucocorticoid receptor. They are often given in doses that are much higher than what the body would normally produce. Taking corticosteroids can lead to a decreased ability to fight off infections and other issues, so it's important to be aware of these risks before starting treatment.

How Solu-Medrol works in the body

Corticosteroids help reduce swelling and inflammation in the body. They do this by changing gene expression, preventing white blood cells from moving to sites of inflammation, and reducing the production of substances that cause inflammation. Lower doses are anti-inflammatory, while higher doses are immunosuppressive. Long-term, high doses of corticosteroids can raise sodium levels and lower potassium levels.

When to interrupt dosage

The recommended dosage of Solu-Medrol is contingent upon the identified condition, including Inflammation, Necrobiosis lipoidica diabeticorum and Diuresis. The dosage quantity oscillates, commensurate with the administration technique outlined in the table beneath.

Condition

Dosage

Administration

Mycosis Fungoides

, 40.0 mg/mL, 125.0 mg/mL, 1000.0 mg, 40.0 mg, 100.0 mg/mL, 125.0 mg, 500.0 mg/mL, 1000.0 mg/mL, 500.0 mg, 2000.0 mg, 200.0 mg/mL, 5000.0 mg

, Intramuscular; Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular; Intravenous, Intravenous, Powder, for solution - Intravenous, Powder, for solution, Injection, powder, for solution - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, Intramuscular; Intravenous; Rectal, Powder, for solution - Intramuscular; Intravenous; Rectal, Intracavernous; Intramuscular, Injection, powder, for solution - Intracavernous; Intramuscular, Injection, Injection - Intramuscular; Intravenous, Kit; Powder, for solution - Intramuscular; Intravenous, Kit; Powder, for solution, Kit; Powder - Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous, Kit; Powder

Polymyositis

, 40.0 mg/mL, 125.0 mg/mL, 1000.0 mg, 40.0 mg, 100.0 mg/mL, 125.0 mg, 500.0 mg/mL, 1000.0 mg/mL, 500.0 mg, 2000.0 mg, 200.0 mg/mL, 5000.0 mg

, Intramuscular; Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular; Intravenous, Intravenous, Powder, for solution - Intravenous, Powder, for solution, Injection, powder, for solution - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, Intramuscular; Intravenous; Rectal, Powder, for solution - Intramuscular; Intravenous; Rectal, Intracavernous; Intramuscular, Injection, powder, for solution - Intracavernous; Intramuscular, Injection, Injection - Intramuscular; Intravenous, Kit; Powder, for solution - Intramuscular; Intravenous, Kit; Powder, for solution, Kit; Powder - Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous, Kit; Powder

Addison Disease

, 40.0 mg/mL, 125.0 mg/mL, 1000.0 mg, 40.0 mg, 100.0 mg/mL, 125.0 mg, 500.0 mg/mL, 1000.0 mg/mL, 500.0 mg, 2000.0 mg, 200.0 mg/mL, 5000.0 mg

, Intramuscular; Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular; Intravenous, Intravenous, Powder, for solution - Intravenous, Powder, for solution, Injection, powder, for solution - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, Intramuscular; Intravenous; Rectal, Powder, for solution - Intramuscular; Intravenous; Rectal, Intracavernous; Intramuscular, Injection, powder, for solution - Intracavernous; Intramuscular, Injection, Injection - Intramuscular; Intravenous, Kit; Powder, for solution - Intramuscular; Intravenous, Kit; Powder, for solution, Kit; Powder - Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous, Kit; Powder

Eosinophilic Pneumonia

, 40.0 mg/mL, 125.0 mg/mL, 1000.0 mg, 40.0 mg, 100.0 mg/mL, 125.0 mg, 500.0 mg/mL, 1000.0 mg/mL, 500.0 mg, 2000.0 mg, 200.0 mg/mL, 5000.0 mg

, Intramuscular; Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular; Intravenous, Intravenous, Powder, for solution - Intravenous, Powder, for solution, Injection, powder, for solution - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, Intramuscular; Intravenous; Rectal, Powder, for solution - Intramuscular; Intravenous; Rectal, Intracavernous; Intramuscular, Injection, powder, for solution - Intracavernous; Intramuscular, Injection, Injection - Intramuscular; Intravenous, Kit; Powder, for solution - Intramuscular; Intravenous, Kit; Powder, for solution, Kit; Powder - Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous, Kit; Powder

Dermatitis

, 40.0 mg/mL, 125.0 mg/mL, 1000.0 mg, 40.0 mg, 100.0 mg/mL, 125.0 mg, 500.0 mg/mL, 1000.0 mg/mL, 500.0 mg, 2000.0 mg, 200.0 mg/mL, 5000.0 mg

, Intramuscular; Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular; Intravenous, Intravenous, Powder, for solution - Intravenous, Powder, for solution, Injection, powder, for solution - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, Intramuscular; Intravenous; Rectal, Powder, for solution - Intramuscular; Intravenous; Rectal, Intracavernous; Intramuscular, Injection, powder, for solution - Intracavernous; Intramuscular, Injection, Injection - Intramuscular; Intravenous, Kit; Powder, for solution - Intramuscular; Intravenous, Kit; Powder, for solution, Kit; Powder - Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous, Kit; Powder

Multiple Sclerosis

, 40.0 mg/mL, 125.0 mg/mL, 1000.0 mg, 40.0 mg, 100.0 mg/mL, 125.0 mg, 500.0 mg/mL, 1000.0 mg/mL, 500.0 mg, 2000.0 mg, 200.0 mg/mL, 5000.0 mg

, Intramuscular; Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular; Intravenous, Intravenous, Powder, for solution - Intravenous, Powder, for solution, Injection, powder, for solution - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, Intramuscular; Intravenous; Rectal, Powder, for solution - Intramuscular; Intravenous; Rectal, Intracavernous; Intramuscular, Injection, powder, for solution - Intracavernous; Intramuscular, Injection, Injection - Intramuscular; Intravenous, Kit; Powder, for solution - Intramuscular; Intravenous, Kit; Powder, for solution, Kit; Powder - Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous, Kit; Powder

Trichinosis

, 40.0 mg/mL, 125.0 mg/mL, 1000.0 mg, 40.0 mg, 100.0 mg/mL, 125.0 mg, 500.0 mg/mL, 1000.0 mg/mL, 500.0 mg, 2000.0 mg, 200.0 mg/mL, 5000.0 mg

, Intramuscular; Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular; Intravenous, Intravenous, Powder, for solution - Intravenous, Powder, for solution, Injection, powder, for solution - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, Intramuscular; Intravenous; Rectal, Powder, for solution - Intramuscular; Intravenous; Rectal, Intracavernous; Intramuscular, Injection, powder, for solution - Intracavernous; Intramuscular, Injection, Injection - Intramuscular; Intravenous, Kit; Powder, for solution - Intramuscular; Intravenous, Kit; Powder, for solution, Kit; Powder - Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous, Kit; Powder

Thrombocytopenia

, 40.0 mg/mL, 125.0 mg/mL, 1000.0 mg, 40.0 mg, 100.0 mg/mL, 125.0 mg, 500.0 mg/mL, 1000.0 mg/mL, 500.0 mg, 2000.0 mg, 200.0 mg/mL, 5000.0 mg

, Intramuscular; Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular; Intravenous, Intravenous, Powder, for solution - Intravenous, Powder, for solution, Injection, powder, for solution - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, Intramuscular; Intravenous; Rectal, Powder, for solution - Intramuscular; Intravenous; Rectal, Intracavernous; Intramuscular, Injection, powder, for solution - Intracavernous; Intramuscular, Injection, Injection - Intramuscular; Intravenous, Kit; Powder, for solution - Intramuscular; Intravenous, Kit; Powder, for solution, Kit; Powder - Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous, Kit; Powder

Sarcoidosis

, 40.0 mg/mL, 125.0 mg/mL, 1000.0 mg, 40.0 mg, 100.0 mg/mL, 125.0 mg, 500.0 mg/mL, 1000.0 mg/mL, 500.0 mg, 2000.0 mg, 200.0 mg/mL, 5000.0 mg

, Intramuscular; Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular; Intravenous, Intravenous, Powder, for solution - Intravenous, Powder, for solution, Injection, powder, for solution - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, Intramuscular; Intravenous; Rectal, Powder, for solution - Intramuscular; Intravenous; Rectal, Intracavernous; Intramuscular, Injection, powder, for solution - Intracavernous; Intramuscular, Injection, Injection - Intramuscular; Intravenous, Kit; Powder, for solution - Intramuscular; Intravenous, Kit; Powder, for solution, Kit; Powder - Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous, Kit; Powder

Acute Coryza

, 40.0 mg/mL, 125.0 mg/mL, 1000.0 mg, 40.0 mg, 100.0 mg/mL, 125.0 mg, 500.0 mg/mL, 1000.0 mg/mL, 500.0 mg, 2000.0 mg, 200.0 mg/mL, 5000.0 mg

, Intramuscular; Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular; Intravenous, Intravenous, Powder, for solution - Intravenous, Powder, for solution, Injection, powder, for solution - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, Intramuscular; Intravenous; Rectal, Powder, for solution - Intramuscular; Intravenous; Rectal, Intracavernous; Intramuscular, Injection, powder, for solution - Intracavernous; Intramuscular, Injection, Injection - Intramuscular; Intravenous, Kit; Powder, for solution - Intramuscular; Intravenous, Kit; Powder, for solution, Kit; Powder - Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous, Kit; Powder

Anemia, Hemolytic

, 40.0 mg/mL, 125.0 mg/mL, 1000.0 mg, 40.0 mg, 100.0 mg/mL, 125.0 mg, 500.0 mg/mL, 1000.0 mg/mL, 500.0 mg, 2000.0 mg, 200.0 mg/mL, 5000.0 mg

, Intramuscular; Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular; Intravenous, Intravenous, Powder, for solution - Intravenous, Powder, for solution, Injection, powder, for solution - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, Intramuscular; Intravenous; Rectal, Powder, for solution - Intramuscular; Intravenous; Rectal, Intracavernous; Intramuscular, Injection, powder, for solution - Intracavernous; Intramuscular, Injection, Injection - Intramuscular; Intravenous, Kit; Powder, for solution - Intramuscular; Intravenous, Kit; Powder, for solution, Kit; Powder - Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous, Kit; Powder

Craniotomy

, 40.0 mg/mL, 125.0 mg/mL, 1000.0 mg, 40.0 mg, 100.0 mg/mL, 125.0 mg, 500.0 mg/mL, 1000.0 mg/mL, 500.0 mg, 2000.0 mg, 200.0 mg/mL, 5000.0 mg

, Intramuscular; Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular; Intravenous, Intravenous, Powder, for solution - Intravenous, Powder, for solution, Injection, powder, for solution - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, Intramuscular; Intravenous; Rectal, Powder, for solution - Intramuscular; Intravenous; Rectal, Intracavernous; Intramuscular, Injection, powder, for solution - Intracavernous; Intramuscular, Injection, Injection - Intramuscular; Intravenous, Kit; Powder, for solution - Intramuscular; Intravenous, Kit; Powder, for solution, Kit; Powder - Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous, Kit; Powder

Thyroiditis

, 40.0 mg/mL, 125.0 mg/mL, 1000.0 mg, 40.0 mg, 100.0 mg/mL, 125.0 mg, 500.0 mg/mL, 1000.0 mg/mL, 500.0 mg, 2000.0 mg, 200.0 mg/mL, 5000.0 mg

, Intramuscular; Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular; Intravenous, Intravenous, Powder, for solution - Intravenous, Powder, for solution, Injection, powder, for solution - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, Intramuscular; Intravenous; Rectal, Powder, for solution - Intramuscular; Intravenous; Rectal, Intracavernous; Intramuscular, Injection, powder, for solution - Intracavernous; Intramuscular, Injection, Injection - Intramuscular; Intravenous, Kit; Powder, for solution - Intramuscular; Intravenous, Kit; Powder, for solution, Kit; Powder - Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous, Kit; Powder

exfoliative erythroderma

, 40.0 mg/mL, 125.0 mg/mL, 1000.0 mg, 40.0 mg, 100.0 mg/mL, 125.0 mg, 500.0 mg/mL, 1000.0 mg/mL, 500.0 mg, 2000.0 mg, 200.0 mg/mL, 5000.0 mg

, Intramuscular; Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular; Intravenous, Intravenous, Powder, for solution - Intravenous, Powder, for solution, Injection, powder, for solution - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, Intramuscular; Intravenous; Rectal, Powder, for solution - Intramuscular; Intravenous; Rectal, Intracavernous; Intramuscular, Injection, powder, for solution - Intracavernous; Intramuscular, Injection, Injection - Intramuscular; Intravenous, Kit; Powder, for solution - Intramuscular; Intravenous, Kit; Powder, for solution, Kit; Powder - Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous, Kit; Powder

induction of Diuresis

, 40.0 mg/mL, 125.0 mg/mL, 1000.0 mg, 40.0 mg, 100.0 mg/mL, 125.0 mg, 500.0 mg/mL, 1000.0 mg/mL, 500.0 mg, 2000.0 mg, 200.0 mg/mL, 5000.0 mg

, Intramuscular; Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular; Intravenous, Intravenous, Powder, for solution - Intravenous, Powder, for solution, Injection, powder, for solution - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, Intramuscular; Intravenous; Rectal, Powder, for solution - Intramuscular; Intravenous; Rectal, Intracavernous; Intramuscular, Injection, powder, for solution - Intracavernous; Intramuscular, Injection, Injection - Intramuscular; Intravenous, Kit; Powder, for solution - Intramuscular; Intravenous, Kit; Powder, for solution, Kit; Powder - Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous, Kit; Powder

Diuresis

, 40.0 mg/mL, 125.0 mg/mL, 1000.0 mg, 40.0 mg, 100.0 mg/mL, 125.0 mg, 500.0 mg/mL, 1000.0 mg/mL, 500.0 mg, 2000.0 mg, 200.0 mg/mL, 5000.0 mg

, Intramuscular; Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular; Intravenous, Intravenous, Powder, for solution - Intravenous, Powder, for solution, Injection, powder, for solution - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, Intramuscular; Intravenous; Rectal, Powder, for solution - Intramuscular; Intravenous; Rectal, Intracavernous; Intramuscular, Injection, powder, for solution - Intracavernous; Intramuscular, Injection, Injection - Intramuscular; Intravenous, Kit; Powder, for solution - Intramuscular; Intravenous, Kit; Powder, for solution, Kit; Powder - Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous, Kit; Powder

Arthritis, Gouty

, 40.0 mg/mL, 125.0 mg/mL, 1000.0 mg, 40.0 mg, 100.0 mg/mL, 125.0 mg, 500.0 mg/mL, 1000.0 mg/mL, 500.0 mg, 2000.0 mg, 200.0 mg/mL, 5000.0 mg

, Intramuscular; Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular; Intravenous, Intravenous, Powder, for solution - Intravenous, Powder, for solution, Injection, powder, for solution - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, Intramuscular; Intravenous; Rectal, Powder, for solution - Intramuscular; Intravenous; Rectal, Intracavernous; Intramuscular, Injection, powder, for solution - Intracavernous; Intramuscular, Injection, Injection - Intramuscular; Intravenous, Kit; Powder, for solution - Intramuscular; Intravenous, Kit; Powder, for solution, Kit; Powder - Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous, Kit; Powder

Giant Cell Arteritis

, 40.0 mg/mL, 125.0 mg/mL, 1000.0 mg, 40.0 mg, 100.0 mg/mL, 125.0 mg, 500.0 mg/mL, 1000.0 mg/mL, 500.0 mg, 2000.0 mg, 200.0 mg/mL, 5000.0 mg

, Intramuscular; Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular; Intravenous, Intravenous, Powder, for solution - Intravenous, Powder, for solution, Injection, powder, for solution - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, Intramuscular; Intravenous; Rectal, Powder, for solution - Intramuscular; Intravenous; Rectal, Intracavernous; Intramuscular, Injection, powder, for solution - Intracavernous; Intramuscular, Injection, Injection - Intramuscular; Intravenous, Kit; Powder, for solution - Intramuscular; Intravenous, Kit; Powder, for solution, Kit; Powder - Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous, Kit; Powder

Brain

, 40.0 mg/mL, 125.0 mg/mL, 1000.0 mg, 40.0 mg, 100.0 mg/mL, 125.0 mg, 500.0 mg/mL, 1000.0 mg/mL, 500.0 mg, 2000.0 mg, 200.0 mg/mL, 5000.0 mg

, Intramuscular; Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular; Intravenous, Intravenous, Powder, for solution - Intravenous, Powder, for solution, Injection, powder, for solution - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, Intramuscular; Intravenous; Rectal, Powder, for solution - Intramuscular; Intravenous; Rectal, Intracavernous; Intramuscular, Injection, powder, for solution - Intracavernous; Intramuscular, Injection, Injection - Intramuscular; Intravenous, Kit; Powder, for solution - Intramuscular; Intravenous, Kit; Powder, for solution, Kit; Powder - Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous, Kit; Powder

Dermatomyositis

, 40.0 mg/mL, 125.0 mg/mL, 1000.0 mg, 40.0 mg, 100.0 mg/mL, 125.0 mg, 500.0 mg/mL, 1000.0 mg/mL, 500.0 mg, 2000.0 mg, 200.0 mg/mL, 5000.0 mg

, Intramuscular; Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intramuscular; Intravenous, Intravenous, Powder, for solution - Intravenous, Powder, for solution, Injection, powder, for solution - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intramuscular; Intravenous, Intramuscular; Intravenous; Rectal, Powder, for solution - Intramuscular; Intravenous; Rectal, Intracavernous; Intramuscular, Injection, powder, for solution - Intracavernous; Intramuscular, Injection, Injection - Intramuscular; Intravenous, Kit; Powder, for solution - Intramuscular; Intravenous, Kit; Powder, for solution, Kit; Powder - Intramuscular; Intravenous, Powder, for solution - Intramuscular; Intravenous, Kit; Powder

Warnings

Solu-Medrol Contraindications

Condition

Risk Level

Notes

intrathecal administration

Do Not Combine

Mycoses

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Methylprednisolone Hemisuccinate may interact with Pulse Frequency

There are 20 known major drug interactions with Solu-Medrol.

Common Solu-Medrol Drug Interactions

Drug Name

Risk Level

Description

Aldesleukin

Major

The therapeutic efficacy of Aldesleukin can be decreased when used in combination with Methylprednisolone hemisuccinate.

Corticorelin ovine triflutate

Major

The therapeutic efficacy of Corticorelin ovine triflutate can be decreased when used in combination with Methylprednisolone hemisuccinate.

Macimorelin

Major

The therapeutic efficacy of Macimorelin can be decreased when used in combination with Methylprednisolone hemisuccinate.

1,10-Phenanthroline

Minor

The therapeutic efficacy of 1,10-Phenanthroline can be decreased when used in combination with Methylprednisolone hemisuccinate.

Aceclofenac

Minor

The risk or severity of gastrointestinal irritation can be increased when Methylprednisolone hemisuccinate is combined with Aceclofenac.

Solu-Medrol Toxicity & Overdose Risk

The toxic dose of glucocorticoids in rats is more than 4g/kg. In mice, the toxic dose is 2292mg/kg, and in rats it is 100mg/kg. If a person takes a large amount of glucocorticoids chronically, they may experience cataracts, glaucoma, high blood pressure, water retention, high cholesterol, ulcers, pancreatitis, muscle weakness, mood changes, psychosis, thinning skin, allergies, acne, increased body hair, lowered immunity, moon face, high blood sugar, low calcium or phosphate levels, acidosis, stunted growth,

image of a doctor in a lab doing drug, clinical research

Solu-Medrol Novel Uses: Which Conditions Have a Clinical Trial Featuring Solu-Medrol?

594 active clinical trials are currently examining the potential of Solu-Medrol to mitigate Asthma, Atopic Dermatitis and Ulcerative Colitis.

Condition

Clinical Trials

Trial Phases

Metastatic Brain Tumors

56 Actively Recruiting

Not Applicable, Phase 1, Phase 2, Phase 3, Early Phase 1, Phase 4

Psoriatic Arthritis

30 Actively Recruiting

Phase 3, Not Applicable, Phase 1, Phase 4, Phase 2

Ulcerative Colitis

14 Actively Recruiting

Phase 3, Phase 2, Not Applicable, Phase 4, Phase 1

Thrombocytopenia

0 Actively Recruiting

Palliative Treatment

1 Actively Recruiting

Phase 3

Berylliosis

0 Actively Recruiting

Adrenal Insufficiency

0 Actively Recruiting

Diuresis

0 Actively Recruiting

Anemia, Hemolytic

0 Actively Recruiting

Brain

0 Actively Recruiting

Brain

7 Actively Recruiting

Phase 1, Phase 2, Not Applicable, Early Phase 1

Lupus Erythematosus

3 Actively Recruiting

Phase 4, Phase 1, Not Applicable

Crohn Disease

0 Actively Recruiting

Subarachnoid Block

0 Actively Recruiting

Stevens-Johnson Syndrome

1 Actively Recruiting

Phase 1

exfoliative erythroderma

0 Actively Recruiting

Arthritis, Gouty

0 Actively Recruiting

Multiple Sclerosis

0 Actively Recruiting

Craniotomy

0 Actively Recruiting

Addison Disease

0 Actively Recruiting

Solu-Medrol Reviews: What are patients saying about Solu-Medrol?

5

Patient Review

8/21/2013

Solu-Medrol for Rheumatoid Arthritis

Solumedral has been an absolute wonder drug for me. I was experiencing debilitating side effects from Taxol and Carbo Platin, but this medication (along with a few others) have almost completely alleviated them.

5

Patient Review

4/18/2013

Solu-Medrol for Allergic Reaction caused by a Drug

I didn't notice any difference.

4.7

Patient Review

1/17/2014

Solu-Medrol for Multiple Sclerosis

I had an allergic reaction and used my EpiPen. I went to the ER and they gave me IV Benadryl and Solu-Medrol. The Solu-Medrol made me so anxious that I had tachycardia. I felt awful. I was stuck in the ER for 5 hours until the tachycardia subsided.

4.7

Patient Review

4/2/2017

Solu-Medrol for Eye Disorder

I experienced some serious side effects while using this medication, but it was effective in reducing the inflammation in my eyes. I no longer have double vision and have recovered most of the mobility in my eyes.

4.3

Patient Review

8/20/2014

Solu-Medrol for Multiple Sclerosis

It's easy for me to administer this treatment; the home health nurse starts it when I receive the first dose. I have a port because I have another blood condition which requires monthly IV infusions. This isn't my first time dealing with this, so I'm familiar with the process and not too worried. My blood pressure is going up, but that might just be because I'm in severe pain right now.

4.3

Patient Review

9/12/2013

Solu-Medrol for Allergic Reaction caused by a Drug

The only issue I had was that it made it difficult for me to sleep; other than that, great results.

4

Patient Review

7/11/2014

Solu-Medrol for Multiple Sclerosis

The monthly IV treatment for my Dermatomyositis has allowed me to walk without stumbling or falling. I'm grateful that we found this option, as it is less invasive than other options (e.g. daily steroid prescriptions) and the positive effects last for almost a month.

4

Patient Review

11/6/2012

Solu-Medrol for Joint Disease which may include Attacks of Acute Arthritis

Though the treatments themselves were easy enough, I've been struggling with some nasty side effects like low blood pressure, weakness and fatigue. I'm just hoping these will pass soon.

4

Patient Review

5/9/2013

Solu-Medrol for Multiple Sclerosis

I have Familial Mediterranean Fever and this medication really helps me a lot when I need to stop a flare-up. The side effects can be intense for me, but the results are worth it.

4

Patient Review

12/21/2016

Solu-Medrol for Eye Disorder

This solumedrol really helped with the inflammation in my eye that prednisone couldn't touch. The swelling is gone now, but my vision is still a bit impaired. The only other downside was a headache and slightly higher blood pressure, but those were manageable.

3.7

Patient Review

9/4/2015

Solu-Medrol for Acute Exacerbation of Multiple Sclerosis

I had this infusion done through a port and it was very effective. I only experienced some soreness in my tongue and throat, which may or may not be related to the treatment.

3.7

Patient Review

8/5/2015

Solu-Medrol for Multiple Sclerosis

I experienced some soreness, gastrointestinal issues, and my tongue felt raw after taking this medication.

2.7

Patient Review

7/29/2012

Solu-Medrol for Multiple Sclerosis

2

Patient Review

11/3/2012

Solu-Medrol for Multiple Sclerosis

1.3

Patient Review

11/25/2016

Solu-Medrol for Thyroid Gland Inflammation

My face swells up easily. I can't eat yogurt.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about solu-medrol

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How long does Solu-Medrol take to work?

"The medicine will have an effect 6 to 48 hours after it is injected into a muscle. Its effect will be noticeable sooner if it is injected into a vein."

Answered by AI

Is Solu-Medrol the same as prednisone?

"A lower dosage of methylprednisolone is used because it is slightly stronger than prednisone."

Answered by AI

What is Solu-Medrol used for?

"This medication can help to relieve symptoms associated with different medical conditions, including arthritis, blood disorders, severe allergies, certain types of cancer, eye conditions, and skin, kidney, intestinal, and lung diseases. It can also be used to help improve the function of the immune system."

Answered by AI

Is Solu-Medrol a steroid?

"The drug also acts as an immunosuppressant, and is used in the preventative treatment of organ transplantation.

Solu-Medrol is a man-made steroid. It is used to treat severe allergies, skin diseases, hormone disorders, gut diseases, and joint diseases. It also suppresses the immune system, and is used to prevent organ transplant rejection."

Answered by AI

Clinical Trials for Solu-Medrol

Image of Princess Margaret Cancer Centre, University Health Network in Toronto, Canada.

Cognitive Stepped Care Program for Brain Cancer

18+
All Sexes
Toronto, Canada

Background: Cognitive symptoms are common and often severe in patients with brain metastases, significantly impacting their quality of life and ability to manage cancer care. Currently, there is no standard approach for routinely assessing and managing these symptoms in oncology clinics. Objective: This study aims to evaluate the feasibility, acceptability, and preliminary efficacy of the Cognitive Stepped Care Program (CSCP) in a Brain Metastases Clinic. Methods: This is a prospective, mixed-methods feasibility study involving patients with brain metastases, their caregivers, and clinic staff. Patients will undergo routine cognitive symptom screening using a standardized tool. Based on symptom severity, they will receive tiered interventions ranging from no support, to education materials, to computerized cognitive testing with individualized debrief, with group strategy training and/or neuropsychological consultation, as needed. Patients will complete questionnaires before and after the intervention regarding their symptoms and quality of life. Patients, caregivers and staff will provide their feedback about the intervention through questionnaires and interviews. Outcomes: Primary outcomes include feasibility and acceptability of the CSCP. Secondary outcomes include preliminary changes in cognitive symptoms, self-efficacy, and quality of life. Significance: This study will inform the potential integration of a structured cognitive support program into standard care for patients with brain metastases and may provide a model for similar interventions in other oncology settings.

Recruiting
Has No Placebo

Princess Margaret Cancer Centre, University Health Network

Image of McMaster Children's Hospital - Digestive Diseases Clinic in Hamilton, Canada.

Vancomycin for Ulcerative Colitis

18+
All Sexes
Hamilton, Canada

This clinical trial tests if oral vancomycin can safely treat active ulcerative colitis (UC) in adults who also have primary sclerosing cholangitis (PSC), a liver condition. The main questions it aims to answer are: * Can oral vancomycin improve UC symptoms as measured by Mayo score at 4 weeks? * Is oral vancomycin safe and tolerable in this patient group? Participants will be compared to see if vancomycin works better than placebo. Participants will: * Take oral vancomycin (250 mg twice daily) or identical placebo capsules for 4 weeks * Have the option for 4 more weeks of open-label vancomycin after the blinded phase * Attend clinic visits at baseline, week 4, and follow-up for Mayo scoring, endoscopy, blood/stool tests, and safety checks * Track treatment adherence and side effects The study primarily assesses if the trial can recruit 14 participants, retain them, achieve good adherence, and follow protocol procedures (feasibility). Secondary goals include safety (adverse events) and early signs of benefit in UC activity, liver tests, and gut bacteria balance. This pilot will guide larger future studies.

Phase 2
Waitlist Available

McMaster Children's Hospital - Digestive Diseases Clinic

Neeraj Narula, MD

Have you considered Solu-Medrol clinical trials?

We made a collection of clinical trials featuring Solu-Medrol, we think they might fit your search criteria.
Go to Trials

Have you considered Solu-Medrol clinical trials?

We made a collection of clinical trials featuring Solu-Medrol, we think they might fit your search criteria.
Go to Trials
Image of Investigative Site in Beverly Hills, United States.

VENT-03 for Lupus

18 - 80
All Sexes
Beverly Hills, CA

The goal of this clinical trial is to learn if VENT-03 works to treat patients with cutaneous lupus erythematosus (CLE) who may or may not have systemic lupus erythematosus (SLE). Another goal is to learn about the safety of VENT-03 and how it is processed by the body. The main questions it aims to answer are: * Does VENT-03 affect the activity and severity of CLE? * What side effects do participants have when taking VENT-03? Researchers will compare VENT-03 to a placebo (a look-alike substance that contains no drug) to see if VENT-03 works to treat patients with CLE. Participants will: * Take VENT-03 or a placebo e for 4 weeks, then all participants will switch to VENT-03 for another 8 weeks; * Visit the clinic once a month for checkups and tests.

Phase 2
Recruiting

Investigative Site (+9 Sites)

Ventus Therapeutics U.S., Inc.

Image of University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center in Cleveland, United States.

Whole Brain Radiotherapy for Brain Cancer

18+
All Sexes
Cleveland, OH

Participants in this research study have cancer that has spread to their brain, called brain metastases. One treatment for this type of cancer is called whole brain radiotherapy that stays away from a specific neurocognitive substructure, called the hippocampus, combined with medication to preserve cognitive function. This study compares that approach to another approach of whole brain radiotherapy that stays away from additional structures that are thought to have a role in cognitive function. Researchers want to see if there is a difference in the preservation of cognitive function between these two approaches.

Phase 2
Waitlist Available

University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center

Haley Perlow, MD

Image of Sunnybrook Health Sciences Centre in Toronto, Canada.

Steroids for Rheumatoid Arthritis

18+
All Sexes
Toronto, Canada

People living with rheumatoid arthritis (RA) often experience flares-periods where their symptoms suddenly get worse. These flares can cause significant pain, make it harder to move and do daily activities, and lower overall quality of life. Doctors often treat flares with medications called glucocorticoids (GCs), which reduce inflammation. These medications can be taken by mouth (oral/PO) or given as a single injection into the muscle (intramuscular/IM). However, it's not clear which option works better from the patient's point of view-especially when it comes to relief of symptoms, improvements in function, and satisfaction with treatment. Most research so far has focused on how well the drugs control the disease, rather than how they impact the patient's overall experience. Research Questions: 1. Does a single GC injection work just as well as taking pills over a few weeks in improving symptoms reported by patients? 2. How do the two treatments compare in terms of symptom relief, ability to function, and patient satisfaction? 3. What do patients think and feel about using GCs to treat RA flares? What the Investigators Think: The investigators believe that a one-time GC injection is just as good as taking pills for a few weeks when it comes to managing RA flares. In fact, the injection might even be safer and preferred by patients. What the Investigators are Doing: The investigators will study 220 adults with RA who are currently having a flare (with at least 3 swollen and tender joints). These patients will be recruited from rheumatology clinics at the University of Toronto and must not have used GCs in the past month. They will be randomly assigned to receive either: A single injection (Methylprednisolone 120 mg), or Oral pills (Prednisone starting at 15 mg daily and tapering down over 3 weeks). The main thing the investigators will look at is how much better patients feel after 6 weeks, based on a questionnaire designed to measure RA flares. The investigators will also look at how well they function, how satisfied they are with the treatment, and whether they had any side effects. In addition, 20 patients (10 from each group) will be interviewed to understand their experiences and opinions about flare treatment in more detail. Why This Is Possible: The investigators have already surveyed University of Toronto rheumatologists who support the idea and provided input on study design. The investigators have also partnered with experts in research methods, national arthritis organizations, and patient groups to make sure the study is relevant and meaningful. Ethics approval has been obtained. Why It Matters: RA flares can have a major impact on people's lives. While current treatments help control inflammation, the investigators need to better understand how these treatments affect people from their own perspective. This study will shift the focus to what matters most to patients, helping doctors and patients choose the best treatment based not only on medical results but also on the patient's experience. This could lead to more effective and personalized care for people living with RA.

Phase 4
Waitlist Available

Sunnybrook Health Sciences Centre (+4 Sites)

Have you considered Solu-Medrol clinical trials?

We made a collection of clinical trials featuring Solu-Medrol, we think they might fit your search criteria.
Go to Trials