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What is Rythmol
PropafenoneThe Generic name of this drug
Treatment SummaryAmiodarone is a drug used to treat irregular heart rhythms, especially those that originate from the ventricles. It also has a mild effect of blocking certain hormones in the body. Amiodarone is well-tolerated and safe for most patients.
Propafenone HClis the brand name
Rythmol Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Propafenone HCl
Propafenone
2000
140
Approved as Treatment by the FDA
Propafenone, otherwise called Propafenone HCl, is approved by the FDA for 1 uses including Atrial Fibrillation .Atrial Fibrillation
Helps manage Atrial Fibrillation
Effectiveness
How Rythmol Affects PatientsPropafenone helps regulate abnormal heart rhythms by blocking sodium from entering the heart cells. This helps stabilize the heart muscle and reduce excitation. It also has local anesthetic effects, similar to the effects of procaine. Propafenone is used to treat atrial and ventricular arrhythmias.
How Rythmol works in the bodyPropafenone helps to treat irregular heartbeats. It reduces the flow of sodium ions in the heart, which slows the speed of the electrical current that causes the heartbeat. This also increases the time needed for the heart muscle to reset between beats. Propafenone also decreases the chance for a spontaneous or triggered irregular beat. However, its effects on calcium ions are not thought to be related to its antiarrhythmic properties.
When to interrupt dosage
The proposed dosage of Rythmol is contingent upon the indicated condition, such as Paroxysmal Supraventricular Tachycardia (PSVT), Atrial Fibrillation and Atrial Fibrillation. The volume of dosage changes, depending on the method of delivery (e.g. Tablet, coated or Oral) detailed in the following table.Condition
Dosage
Administration
Atrial Fibrillation
, 225.0 mg, 325.0 mg, 425.0 mg, 150.0 mg, 300.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral
Ventricular Arrhythmia
, 225.0 mg, 325.0 mg, 425.0 mg, 150.0 mg, 300.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral
Paroxysmal Atrial Fibrillation
, 225.0 mg, 325.0 mg, 425.0 mg, 150.0 mg, 300.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral
Paroxysmal Supraventricular Tachycardia (PSVT)
, 225.0 mg, 325.0 mg, 425.0 mg, 150.0 mg, 300.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral
Warnings
Rythmol ContraindicationsCondition
Risk Level
Notes
Cerebral Ventricle Neoplasms
Do Not Combine
Slow Heart Rate
Do Not Combine
Congestive Heart Failure
Do Not Combine
Cerebral Ventricle Neoplasms
Do Not Combine
Lung Diseases, Obstructive
Do Not Combine
Sinus Arrhythmia
Do Not Combine
Sinus Arrhythmia
Do Not Combine
Atrioventricular Block
Do Not Combine
Marked electrolyte imbalance
Do Not Combine
Brugada Syndrome (BrS)
Do Not Combine
Shock, Cardiogenic
Do Not Combine
Atrioventricular Block
Do Not Combine
Hypotension
Do Not Combine
Bronchospasm
Do Not Combine
Common Rythmol Drug Interactions
Drug Name
Risk Level
Description
4-Bromo-2,5-dimethoxyphenethylamine
Major
The therapeutic efficacy of 4-Bromo-2,5-dimethoxyphenethylamine can be decreased when used in combination with Propafenone.
4-Methoxyamphetamine
Major
The metabolism of 4-Methoxyamphetamine can be decreased when combined with Propafenone.
5-methoxy-N,N-dimethyltryptamine
Major
The metabolism of 5-methoxy-N,N-dimethyltryptamine can be decreased when combined with Propafenone.
Abediterol
Major
The therapeutic efficacy of Abediterol can be decreased when used in combination with Propafenone.
Abemaciclib
Major
The serum concentration of Abemaciclib can be increased when it is combined with Propafenone.
Rythmol Toxicity & Overdose RiskOverdosing on propafenone can cause convulsions, abnormal heart rhythms, low blood pressure, and drowsiness. These symptoms are typically most severe within the first 3 hours after overdosing.
Rythmol Novel Uses: Which Conditions Have a Clinical Trial Featuring Rythmol?
175 ongoing clinical trials are currently assessing the potential of Rythmol to treat Ventricular Arrhythmia, Atrial Fibrillation and other Atrial Fibrillation-related conditions.Condition
Clinical Trials
Trial Phases
Paroxysmal Supraventricular Tachycardia (PSVT)
2 Actively Recruiting
Phase 3, Phase 2
Atrial Fibrillation
148 Actively Recruiting
Not Applicable, Phase 2, Phase 4, Phase 1, Phase 3, Early Phase 1
Ventricular Arrhythmia
2 Actively Recruiting
Not Applicable
Paroxysmal Atrial Fibrillation
6 Actively Recruiting
Not Applicable, Phase 2
Rythmol Reviews: What are patients saying about Rythmol?
5Patient Review
5/23/2013 Unfortunately, this medication seemed to make my husband's A-fib worse.
5Patient Review
3/5/2014 I've tried a lot of different medications, but they all had terrible side effects. I couldn't have ablation surgery, so my doctor put me on Rythmol. It's been working great! I used to get really bad episodes of PSVT when I got stressed, but since I started taking this medication, I haven't had any problems.
5Patient Review
6/29/2016 I've been taking this medicine for over 20 years and it has really helped me. I used to have arrhythmias that would cause my blood pressure to drop dangerously low. This medication has saved my life on more than one occasion.
5Patient Review
6/12/2013 Rythmol was the only treatment that corrected my atrial fibrillation after 14 years of trying other remedies. You have to be consistent with taking it, but it's worth it if it works for you.
5Patient Review
9/30/2013 I've only been on this medication for two weeks, but it's already working well. My heart rate has decreased significantly and I'm no longer feeling like a zombie.
5Patient Review
6/2/2014 This treatment helped me a lot. I was dealing with atrial fib and this really made a difference.
4.7Patient Review
6/5/2013 This treatment helps to bring my arrhythmia down to a manageable level.
4.3Patient Review
3/26/2015 I have a heart condition called paroxysmal atrial fibrillation. This medication usually helps me within 3-4 doses and doesn't have any negative side effects that I've experienced. The only other medication I'm on is aspirin.
4.3Patient Review
3/20/20134Patient Review
11/26/2016 I was wondering if anyone knew why I shouldn't drink ensure while taking this drug.
3.7Patient Review
3/19/2017 I take Rythmol to manage my atrial fibrillation. It's been working well for the most part, but I have noticed that it really zaps my energy levels when I try to work out.
3.3Patient Review
2/27/2014 I was feeling pretty awful after taking this medication. Dizziness, headaches, loss of appetite, nausea, and fatigue were some of the main issues I experienced. Stopped taking it after a week because I just couldn't handle it anymore.
3Patient Review
5/4/20132Patient Review
8/13/2013 Though my palpitations have decreased since taking Rythmol, cardizem, and Eliquis for symptoms of moderate to severe dizziness, angina, and high blood pressure (as well as a history of blood clots), the dizziness itself has only gotten worse. Has anyone else experienced this?
2Patient Review
2/9/20131Patient Review
8/6/2014 I had a really terrible reaction to this drug. It made me feel like a zombie and my AFib increased in frequency. I would definitely not recommend it to anyone.
Patient Q&A Section about rythmol
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What are the side effects of Rythmol?
"racing heartbeat
The text describes symptoms which may include dizziness, headache, nausea, vomiting, constipation, loss of appetite, anxiety, and a racing heartbeat."
Answered by AI
Is Rythmol a beta blocker?
"Propafenone is not a beta blocker, however it does have some beta-blocking properties. Be careful when taking it with medications that end in -olol, such as metoprolol or carvedilol."
Answered by AI
Does Rythmol slow heart rate?
"Propafenone works by affecting the heart tissue directly and slowing down the nerve impulses in the heart. This can help to keep the heart rhythm normal. However, there is also a chance that propafenone may cause new heart rhythm problems or worsen existing ones when it is used."
Answered by AI
What is the drug Rythmol used for?
"Propafenone is used to treat serious irregular heartbeat, which could be fatal. It is used to restore normal heart rhythm and maintain a regular, steady heartbeat. Propafenone is known as an anti-arrhythmic drug."
Answered by AI