Study Summary
This trial is testing polatuzumab vedotin, a new treatment for aggressive large B-cell lymphoma, in combination with other drugs.
- Non-Hodgkin Lymphoma
- Diffuse Large B-Cell Lymphoma
- ALK-Positive Large B-Cell Lymphoma
- T-Cell/Histiocyte-Rich Large B-Cell Lymphoma
- Primary Mediastinal Large B-Cell Lymphoma
- Epstein-Barr Virus Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
- Non-Hodgkin's Lymphoma
- B-Cell Lymphoma, Unclassifiable, With Features Intermediate Between Diffuse Large B-Cell Lymphoma and Classic Hodgkin Lymphoma
- Double Hit Lymphoma
Treatment Effectiveness
Phase-Based Effectiveness
Study Objectives
1 Primary · 1 Secondary · Reporting Duration: Up to 30 days after last dose of polatuzumab or first administration of alternate therapy
Trial Safety
Phase-Based Safety
Side Effects for
Awards & Highlights
Trial Design
1 Treatment Group
Treatment (polatuzumab vedotin, combination chemotherapy)
1 of 1
Experimental Treatment
50 Total Participants · 1 Treatment Group
Primary Treatment: Rituximab · No Placebo Group · Phase 1
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 18+ · All Participants · 0 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:Frequently Asked Questions
How many test subjects are participating in the ongoing clinical trial?
"Confirmed. Evidently, this clinical trial is currently enrolling participants - it was published on October 27th 2020 and last revised on November 22nd 2022. The investigators are recruiting 50 patients from a single medical centre." - Anonymous Online Contributor
To what maladies is Rituximab typically prescribed?
"Rituximab is often utilized to treat merkel cell cancer but it has been proven effective for a variety of other medical conditions including ophthalmia, sympathetic, and prostate cancer." - Anonymous Online Contributor
Is there still availability for participants in this experiment?
"Affirmative. Clinicaltrials.gov indicates that this trial, which was initially published on October 27th 2020, is actively recruiting individuals for participation. 50 participants need to be enrolled from a single site." - Anonymous Online Contributor
What other exploratory investigations have been conducted concerning Rituximab?
"Presently, 1674 investigations are being conducted on Rituximab. Of those trials, 366 have advanced to the Phase 3 stage at this time. Although most studies occur in Bethesda, Maryland, there are 61190 sites administering tests for this medication worldwide." - Anonymous Online Contributor