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What is Stribild
EmtricitabineThe Generic name of this drug
Treatment SummaryCobicistat (brand name Tybost or formerly GS-9350) is a medication used to help treat HIV. It does not directly fight HIV, but it helps increase the effects of other medications used to treat HIV by blocking certain enzymes in the body. It is most commonly used to increase the effectiveness of atazanavir or darunavir, two anti-retroviral medications used to treat HIV. By increasing the effects of these medications without increasing the dosage, cobicistat can help improve treatment outcomes and reduce side effects.
Emtrivais the brand name
Stribild Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Emtriva
Emtricitabine
2003
131
Approved as Treatment by the FDA
Emtricitabine, also called Emtriva, is approved by the FDA for 2 uses including HIV and adults and pediatric patients weighing at least 17 kg .HIV
Helps manage Human Immunodeficiency Virus Type 1 (HIV-1) Infection
adults and pediatric patients weighing at least 17 kg
Effectiveness
How Stribild works in the bodyCobicistat helps increase the effectiveness of certain HIV medications by blocking the enzymes that break them down. This allows the medications to stay in the body longer, resulting in improved anti-viral activity. Cobicistat is not an anti-HIV drug itself and does not provide any direct benefits.
When to interrupt dosage
The proposed dosage of Stribild is contingent upon the ascertained condition. The measure of dosage is dependent on the technique of administration, which can be found in the table below.Condition
Dosage
Administration
HIV Transmission
200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral
HIV test negative
200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral
HIV
200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral
Anti-Retroviral Agents
200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral
weight more than 35 kg
200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral
weight at least 14 kg
200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral
HIV
200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral
HIV
200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral
HIV Infections
200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral
weight at least 35 kg
200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral
Antiretroviral Therapy
200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral
treatment failure
200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral
adults and pediatric patients weighing at least 17 kg
200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral
Sexual Behaviour
200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral
not requiring CYP3A inhibitors
200.0 mg, , 100.0 mg, 133.0 mg, 167.0 mg, 10.0 mg/mL, 120.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral
Warnings
Stribild ContraindicationsCondition
Risk Level
Notes
HIV
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Emtricitabine may interact with Pulse Frequency
Common Stribild Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The excretion of Abemaciclib can be decreased when combined with Emtricitabine.
Procainamide
Major
The excretion of Procainamide can be decreased when combined with Emtricitabine.
Topotecan
Major
The excretion of Topotecan can be decreased when combined with Emtricitabine.
Cefradine
Minor
The excretion of Cefradine can be decreased when combined with Emtricitabine.
Estrone sulfate
Minor
The excretion of Estrone sulfate can be decreased when combined with Emtricitabine.
Stribild Toxicity & Overdose RiskCommon side effects of this drug include yellowing of the skin or eyes (jaundice), yellowing of the eyes (icterus), and feeling sick to the stomach (nausea).
Stribild Novel Uses: Which Conditions Have a Clinical Trial Featuring Stribild?
165 clinical trials are presently assessing the potential of Stribild in providing relief from HIV and related conditions.Condition
Clinical Trials
Trial Phases
treatment failure
0 Actively Recruiting
HIV Transmission
0 Actively Recruiting
HIV
0 Actively Recruiting
Anti-Retroviral Agents
0 Actively Recruiting
HIV Infections
0 Actively Recruiting
HIV test negative
0 Actively Recruiting
adults and pediatric patients weighing at least 17 kg
0 Actively Recruiting
Antiretroviral Therapy
2 Actively Recruiting
Phase 3, Phase 1
HIV
42 Actively Recruiting
Phase 2, Phase 3, Phase 1, Phase 4, Not Applicable, Early Phase 1
HIV
146 Actively Recruiting
Phase 2, Not Applicable, Phase 1, Phase 3, Phase 4, Early Phase 1
not requiring CYP3A inhibitors
0 Actively Recruiting
weight more than 35 kg
0 Actively Recruiting
weight at least 35 kg
0 Actively Recruiting
weight at least 14 kg
0 Actively Recruiting
Sexual Behaviour
17 Actively Recruiting
Phase 2, Not Applicable, Phase 4
Stribild Reviews: What are patients saying about Stribild?
5Patient Review
4/21/20145Patient Review
10/15/2015 Since beginning treatment with strbilid and dapsone, I have seen a significant decrease in my viral load. My energy levels have also increased, and I no longer feel the need to take naps during the day. I am hopeful that this trend will continue and that I will eventually achieve undetectability.
5Patient Review
9/27/2014 This new pill has really changed my life for the better. I'm so glad I decided to ask my doctor about it.
5Patient Review
6/9/2014 I'm always a bit hesitant about trying new medications, and this one is no exception. That said, it has really helped me in ways that other treatments haven't. I don't have to worry about food restrictions, which is great.
5Patient Review
11/15/2015 I was only taking medication while pregnant, but now that I'm done having kids the HIV was slowly coming back. In just three weeks of taking stribild, my levels went from 9000 to undetectable. There were no side effects in the beginning, but now (4 weeks after my first dose) I've been getting vertigo and headaches more often than not in the evenings.
5Patient Review
8/8/2015 I was diagnosed with HIV in June 2014 and had no idea what to expect. I started this treatment on July 10 and felt a lot better almost immediately. Suddenly, the symptoms of HIV became much clearer. The rash was clearing up and when I went to the doctor on July 29, most of the symptoms had cleared greatly. This drug is amazing!
5Patient Review
8/16/2016 After four weeks of treatment, my VL (viral load) went from 56,000 to just 85! My CD4 (cluster of differentiation 4) count went from 151 to 207. I felt hungover and experienced some anxiety and insomnia the first two weeks; however, I have had zero issues taking it since then. Additionally, I supplement with vitamin D and Selenium. Gilead's copay card covered this medication entirely for me.
5Patient Review
10/30/2014 I was diagnosed in March/April of 2014 and started taking Stribild. Within two weeks, my CD4 had risen to 204 and my VL 5-days into meds dropped to 4,000. I just had my 6 month check up today and my VL is >1 and CD4 is at 298. I've experienced no side effects after some minor things the first 2 weeks (my body healing). I take one every morning and it has made this process much easier to deal with and manage.
4.7Patient Review
7/29/2014 This drug has been great in boosting my CD4 levels, but unfortunately I've developed psoriasis since starting it.
4.7Patient Review
11/21/2015 The dizziness and headaches are unfortunate side effects, but they haven't been bad enough to outweigh the positives of this medication. I'll be contacting my doctor to see what can be done about them, though.
4.3Patient Review
7/12/2014 I've been taking this medication for two years with no negative side effects. It's only once a day, which is really convenient, and it's lowered my viral load to undetectable levels.
4.3Patient Review
4/23/2014 Quick-acting and easy to use, this medication was great with minimal side effects.
4Patient Review
1/11/2016 I had to stop taking this after thirty days when my liver enzymes started spiking. My doctor said it wasn't uncommon, but that if I didn't get off the medication it could cause serious damage. He switched me to Genvoya, which is similar but with less of the ingredient that can cause problems. So far so good!
3.7Patient Review
12/27/2016 I started taking Stribild for my HIV treatment, and it's been absolutely awful. I feel hungover and achy all the time. I'm going back to Atripla tomorrow.
3Patient Review
12/17/2015 I started this treatment two weeks ago and immediately felt pain in my left arm, as well as some headaches and blurred vision. Recently, I've also had acid reflux for the past three days.
1.7Patient Review
9/7/2015 I've been on Sribild for almost three weeks now and have had nothing but terrible side effects like nausea and stomach cramps. I would not recommend this medication to anyone.
Patient Q&A Section about stribild
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Does Stribild cause weight gain?
"Weight gain is not a common side effect for those taking Stribild, however, a recent study shows that some of the newer HIV treatments that contain integrase strand inhibitors like elvitegravir (which is found in Stribild) can be linked to significant weight gain."
Answered by AI
What are the side effects of Stribild?
"You may experience diarrhea, headache, dizziness, trouble sleeping, unusual dreams, back pain, or a change in the color of skin on your palms or soles of your feet. If you experience any of these effects for an extended period of time, or if they get worse, please notify your doctor or pharmacist."
Answered by AI
What is the drug Stribild used for?
"STRIBILD is a prescription medicine that is used to treat Human Immunodeficiency Virus-1 (HIV-1) in people 12 years of age and older, who have not received anti-HIV-1 medicines in the past, or to replace their current anti-HIV-1 medicines: in people who have been on the same anti-HIV-1 medicine regimen for at least 6 months, and who are virologically-suppressed (HIV-1 RNA less than 50 copies/mL)."
Answered by AI
What diagnosis is Stribild?
"Stribild is a medication used to treat HIV. It is prescribed for adults and children ages 12 years and older who weigh at least 35 kilograms (about 77 pounds). Stribild does not need to be taken with other HIV medications."
Answered by AI