Risperdal Consta

Irritability, Autism, Schizophrenia + 10 more
Treatment
3 FDA approvals
20 Active Studies for Risperdal Consta

What is Risperdal Consta

RisperidoneThe Generic name of this drug
Treatment SummaryRisperidone is a medication used to treat schizophrenia, bipolar disorder, and other mood disorders. It works by blocking certain receptors in the brain, including dopamine and serotonin receptors, which helps to reduce the excessive activity of certain pathways in the brain that are believed to cause these disorders. Risperidone is one of the most commonly used second-generation antipsychotics and has a very high affinity for serotonin receptors, which makes it more effective at treating symptoms than other medications.
Risperidoneis the brand name
image of different drug pills on a surface
Risperdal Consta Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Risperidone
Risperidone
1993
522

Approved as Treatment by the FDA

Risperidone, also known as Risperidone, is approved by the FDA for 3 uses such as Bipolar Disorder and Acute Mania .
Bipolar Disorder
Acute Mania
Bipolar Disorder

Effectiveness

How Risperdal Consta Affects PatientsRisperidone works by decreasing activity in the pathways related to dopamine and serotonin in the brain. This helps reduce the symptoms of schizophrenia and other mood disorders. Risperidone binds more strongly to serotonin receptors than dopamine receptors. It has a lower binding affinity for dopamine receptors than earlier drugs, which may explain why it causes fewer side effects related to movement.
How Risperdal Consta works in the bodyRisperidone works by temporarily blocking dopamine and serotonin receptors in the brain. This helps reduce the positive symptoms of schizophrenia, such as delusions and hallucinations. It also reduces the negative symptoms, like depression and decreased motivation, by blocking serotonin receptors. Risperidone also blocks alpha-1, alpha-2 and histamine receptors, though we don't completely understand how this improves symptoms of schizophrenia. By doing all of the above, risperidone reduces the risk of side effects like extrapyramidal symptoms.

When to interrupt dosage

The measure of Risperdal Consta is contingent upon the determined condition, including Psychotic Disorders, Irritability and Acute Mania. The dosage fluctuates as indicated by the technique of delivery (e.g. Subcutaneous or Solution) featured in the table beneath.
Condition
Dosage
Administration
Acute Coryza
, 0.5 mg, 1.0 mg, 2.0 mg, 4.0 mg, 3.0 mg, 0.25 mg, 1.0 mg/mL, 25.0 mg, 37.5 mg, 50.0 mg, 12.5 mg, 5.0 mg, 12.5 mg/mL, 37.5 mg/mL, 50.0 mg/mL, 25.0 mg/mL, 900.0 mg/mL, 1200.0 mg/mL, 120.0 mg, 90.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Tablet, coated, Tablet, coated - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Kit, Kit - Subcutaneous, Subcutaneous, Kit; Powder, for suspension, Kit; Powder, for suspension - Subcutaneous, Injection, powder, for suspension, extended release; Kit - Subcutaneous
Bipolar Disorder
, 0.5 mg, 1.0 mg, 2.0 mg, 4.0 mg, 3.0 mg, 0.25 mg, 1.0 mg/mL, 25.0 mg, 37.5 mg, 50.0 mg, 12.5 mg, 5.0 mg, 12.5 mg/mL, 37.5 mg/mL, 50.0 mg/mL, 25.0 mg/mL, 900.0 mg/mL, 1200.0 mg/mL, 120.0 mg, 90.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Tablet, coated, Tablet, coated - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Kit, Kit - Subcutaneous, Subcutaneous, Kit; Powder, for suspension, Kit; Powder, for suspension - Subcutaneous, Injection, powder, for suspension, extended release; Kit - Subcutaneous
Irritability
, 0.5 mg, 1.0 mg, 2.0 mg, 4.0 mg, 3.0 mg, 0.25 mg, 1.0 mg/mL, 25.0 mg, 37.5 mg, 50.0 mg, 12.5 mg, 5.0 mg, 12.5 mg/mL, 37.5 mg/mL, 50.0 mg/mL, 25.0 mg/mL, 900.0 mg/mL, 1200.0 mg/mL, 120.0 mg, 90.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Tablet, coated, Tablet, coated - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Kit, Kit - Subcutaneous, Subcutaneous, Kit; Powder, for suspension, Kit; Powder, for suspension - Subcutaneous, Injection, powder, for suspension, extended release; Kit - Subcutaneous
Schizophrenia
, 0.5 mg, 1.0 mg, 2.0 mg, 4.0 mg, 3.0 mg, 0.25 mg, 1.0 mg/mL, 25.0 mg, 37.5 mg, 50.0 mg, 12.5 mg, 5.0 mg, 12.5 mg/mL, 37.5 mg/mL, 50.0 mg/mL, 25.0 mg/mL, 900.0 mg/mL, 1200.0 mg/mL, 120.0 mg, 90.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Tablet, coated, Tablet, coated - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Kit, Kit - Subcutaneous, Subcutaneous, Kit; Powder, for suspension, Kit; Powder, for suspension - Subcutaneous, Injection, powder, for suspension, extended release; Kit - Subcutaneous
Behcet Syndrome
, 0.5 mg, 1.0 mg, 2.0 mg, 4.0 mg, 3.0 mg, 0.25 mg, 1.0 mg/mL, 25.0 mg, 37.5 mg, 50.0 mg, 12.5 mg, 5.0 mg, 12.5 mg/mL, 37.5 mg/mL, 50.0 mg/mL, 25.0 mg/mL, 900.0 mg/mL, 1200.0 mg/mL, 120.0 mg, 90.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Tablet, coated, Tablet, coated - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Kit, Kit - Subcutaneous, Subcutaneous, Kit; Powder, for suspension, Kit; Powder, for suspension - Subcutaneous, Injection, powder, for suspension, extended release; Kit - Subcutaneous
responsive to first treatment
, 0.5 mg, 1.0 mg, 2.0 mg, 4.0 mg, 3.0 mg, 0.25 mg, 1.0 mg/mL, 25.0 mg, 37.5 mg, 50.0 mg, 12.5 mg, 5.0 mg, 12.5 mg/mL, 37.5 mg/mL, 50.0 mg/mL, 25.0 mg/mL, 900.0 mg/mL, 1200.0 mg/mL, 120.0 mg, 90.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Tablet, coated, Tablet, coated - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Kit, Kit - Subcutaneous, Subcutaneous, Kit; Powder, for suspension, Kit; Powder, for suspension - Subcutaneous, Injection, powder, for suspension, extended release; Kit - Subcutaneous
Autism
, 0.5 mg, 1.0 mg, 2.0 mg, 4.0 mg, 3.0 mg, 0.25 mg, 1.0 mg/mL, 25.0 mg, 37.5 mg, 50.0 mg, 12.5 mg, 5.0 mg, 12.5 mg/mL, 37.5 mg/mL, 50.0 mg/mL, 25.0 mg/mL, 900.0 mg/mL, 1200.0 mg/mL, 120.0 mg, 90.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Tablet, coated, Tablet, coated - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Kit, Kit - Subcutaneous, Subcutaneous, Kit; Powder, for suspension, Kit; Powder, for suspension - Subcutaneous, Injection, powder, for suspension, extended release; Kit - Subcutaneous
Schizophrenia
, 0.5 mg, 1.0 mg, 2.0 mg, 4.0 mg, 3.0 mg, 0.25 mg, 1.0 mg/mL, 25.0 mg, 37.5 mg, 50.0 mg, 12.5 mg, 5.0 mg, 12.5 mg/mL, 37.5 mg/mL, 50.0 mg/mL, 25.0 mg/mL, 900.0 mg/mL, 1200.0 mg/mL, 120.0 mg, 90.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Tablet, coated, Tablet, coated - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Kit, Kit - Subcutaneous, Subcutaneous, Kit; Powder, for suspension, Kit; Powder, for suspension - Subcutaneous, Injection, powder, for suspension, extended release; Kit - Subcutaneous
Bipolar Disorder
, 0.5 mg, 1.0 mg, 2.0 mg, 4.0 mg, 3.0 mg, 0.25 mg, 1.0 mg/mL, 25.0 mg, 37.5 mg, 50.0 mg, 12.5 mg, 5.0 mg, 12.5 mg/mL, 37.5 mg/mL, 50.0 mg/mL, 25.0 mg/mL, 900.0 mg/mL, 1200.0 mg/mL, 120.0 mg, 90.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Tablet, coated, Tablet, coated - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Kit, Kit - Subcutaneous, Subcutaneous, Kit; Powder, for suspension, Kit; Powder, for suspension - Subcutaneous, Injection, powder, for suspension, extended release; Kit - Subcutaneous
Psychotic Disorders
, 0.5 mg, 1.0 mg, 2.0 mg, 4.0 mg, 3.0 mg, 0.25 mg, 1.0 mg/mL, 25.0 mg, 37.5 mg, 50.0 mg, 12.5 mg, 5.0 mg, 12.5 mg/mL, 37.5 mg/mL, 50.0 mg/mL, 25.0 mg/mL, 900.0 mg/mL, 1200.0 mg/mL, 120.0 mg, 90.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Tablet, coated, Tablet, coated - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Kit, Kit - Subcutaneous, Subcutaneous, Kit; Powder, for suspension, Kit; Powder, for suspension - Subcutaneous, Injection, powder, for suspension, extended release; Kit - Subcutaneous
Alzheimer's Disease
, 0.5 mg, 1.0 mg, 2.0 mg, 4.0 mg, 3.0 mg, 0.25 mg, 1.0 mg/mL, 25.0 mg, 37.5 mg, 50.0 mg, 12.5 mg, 5.0 mg, 12.5 mg/mL, 37.5 mg/mL, 50.0 mg/mL, 25.0 mg/mL, 900.0 mg/mL, 1200.0 mg/mL, 120.0 mg, 90.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Tablet, coated, Tablet, coated - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Kit, Kit - Subcutaneous, Subcutaneous, Kit; Powder, for suspension, Kit; Powder, for suspension - Subcutaneous, Injection, powder, for suspension, extended release; Kit - Subcutaneous
Acute Mania
, 0.5 mg, 1.0 mg, 2.0 mg, 4.0 mg, 3.0 mg, 0.25 mg, 1.0 mg/mL, 25.0 mg, 37.5 mg, 50.0 mg, 12.5 mg, 5.0 mg, 12.5 mg/mL, 37.5 mg/mL, 50.0 mg/mL, 25.0 mg/mL, 900.0 mg/mL, 1200.0 mg/mL, 120.0 mg, 90.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Tablet, coated, Tablet, coated - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Kit, Kit - Subcutaneous, Subcutaneous, Kit; Powder, for suspension, Kit; Powder, for suspension - Subcutaneous, Injection, powder, for suspension, extended release; Kit - Subcutaneous
Schizophrenia
, 0.5 mg, 1.0 mg, 2.0 mg, 4.0 mg, 3.0 mg, 0.25 mg, 1.0 mg/mL, 25.0 mg, 37.5 mg, 50.0 mg, 12.5 mg, 5.0 mg, 12.5 mg/mL, 37.5 mg/mL, 50.0 mg/mL, 25.0 mg/mL, 900.0 mg/mL, 1200.0 mg/mL, 120.0 mg, 90.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Tablet, coated, Tablet, coated - Oral, Intramuscular, Injection, powder, for suspension, extended release; Kit, Injection, powder, for suspension, extended release; Kit - Intramuscular, Kit, Kit - Subcutaneous, Subcutaneous, Kit; Powder, for suspension, Kit; Powder, for suspension - Subcutaneous, Injection, powder, for suspension, extended release; Kit - Subcutaneous

Warnings

Risperdal Consta Contraindications
Condition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Risperidone may interact with Pulse Frequency
Pulse Frequency
Do Not Combine
There are 20 known major drug interactions with Risperdal Consta.
Common Risperdal Consta Drug Interactions
Drug Name
Risk Level
Description
Acepromazine
Major
Risperidone may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Acepromazine.
Alfuzosin
Major
Risperidone may increase the hypotensive activities of Alfuzosin.
Amisulpride
Major
Risperidone may increase the antipsychotic activities of Amisulpride.
Aripiprazole
Major
Risperidone may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Aripiprazole.
Aripiprazole lauroxil
Major
Risperidone may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Aripiprazole lauroxil.
Risperdal Consta Toxicity & Overdose RiskOverdosing on Haloperidol can cause drowsiness, muscle spasms, rapid heartbeat, slow heartbeat and seizures. The lowest lethal dose in rats is 57.7 mg/kg when taken orally and 34 mg/kg when injected intravenously.
image of a doctor in a lab doing drug, clinical research

Risperdal Consta Novel Uses: Which Conditions Have a Clinical Trial Featuring Risperdal Consta?

359 active studies are currently evaluating the potential of Risperdal Consta to mitigate Acute Mania, Bipolar Disorder and Autism.
Condition
Clinical Trials
Trial Phases
Psychotic Disorders
0 Actively Recruiting
Behcet Syndrome
2 Actively Recruiting
Not Applicable
Bipolar Disorder
1 Actively Recruiting
Phase 4
Acute Mania
0 Actively Recruiting
Schizophrenia
34 Actively Recruiting
Early Phase 1, Not Applicable, Phase 4
responsive to first treatment
0 Actively Recruiting
Bipolar Disorder
0 Actively Recruiting
Schizophrenia
0 Actively Recruiting
Alzheimer's Disease
31 Actively Recruiting
Phase 2, Not Applicable, Phase 1, Phase 3
Autism
137 Actively Recruiting
Phase 3, Not Applicable, Phase 2, Phase 1, Phase 4, Early Phase 1
Schizophrenia
174 Actively Recruiting
Not Applicable, Phase 3, Phase 2, Early Phase 1, Phase 4, Phase 1
Acute Coryza
1 Actively Recruiting
Not Applicable
Irritability
4 Actively Recruiting
Not Applicable, Phase 4

Risperdal Consta Reviews: What are patients saying about Risperdal Consta?

4.3Patient Review
2/23/2013
Risperdal Consta for Schizophrenia
On behalf of my son, who died by suicide after 3 attempts, I want to warn others about the risks associated with Risperdal Consta injections.
3Patient Review
6/29/2015
Risperdal Consta for Schizophrenia
One downside to this medication is that it caused weight gain in my son. He ended up in the hospital for nine days as a result of vomiting, excessive thirst, and sleepiness. Doctors discovered upon his arrival that he had high blood sugar levels (nearly 467).
2.7Patient Review
5/26/2015
Risperdal Consta for Schizophrenia
I'm new to this drug, and so far I like it. However, I can see why some people wouldn't recommend it based on how painful it is to administer. It burns and you can hardly move your arm or hand afterwards.
2Patient Review
3/5/2014
Risperdal Consta for Bipolar Disorder in Remission
Risperdal Consta has been very beneficial for me in terms of keeping my mood and behavior stable. I preferred it to the oral version of the medication, and would highly recommend it to others.
2Patient Review
9/6/2012
Risperdal Consta for Schizophrenia
I'm struggling to afford this medication for my son. It's been helping him, so I hope we can find a way to keep paying for it.
1.7Patient Review
7/22/2014
Risperdal Consta for Bipolar Disorder in Remission
I've taken Risperdal injections for 4 months for Bipolar. It makes my concentration poor and I feel dead and in limbo.
1.7Patient Review
9/6/2018
Risperdal Consta for Schizophrenia
This drug made me feel awful. I couldn't get up or do anything, my speech was slurred, and it felt like it half-destroyed my brain. I used to be in great shape, but now I've gained twenty pounds. If given the choice, I would rather be slightly deranged than have to take this medication, but unfortunately society has forced me into this position.
1.3Patient Review
4/1/2015
Risperdal Consta for Manic-Depression
I've been on this for five months and it's done nothing but make me suffer. I've gained weight, lost my sex drive, and can't sleep. My psychiatrist won't let me stop taking it even though it's clearly not working.
1Patient Review
11/26/2011
Risperdal Consta for Schizophrenia
1Patient Review
11/27/2011
Risperdal Consta for Schizophrenia
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about risperdal consta

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is RISPERDAL CONSTA injection?

"This medication is indicated to be used either on its own or alongside lithium or valproate in order to maintain treatment for Bipolar I Disorder, or to treat schizophrenia."

Answered by AI

How often is RISPERDAL CONSTA given?

"For gluteal administration, use the 1.5-inch needle. Cleanse the top of the vial with an alcohol swab. Remove the cap from the vial adapter and insert it into the vial.

The drugs RISPERDAL CONSTA should be given every two weeks by a deep intramuscular injection either into the deltoid muscle of the shoulder or into the gluteal muscle of the buttocks, using the safety needles provided. If you are injecting into the deltoid muscle, use the 1-inch needle and alternate between injecting into the two arms. If you are injecting into the gluteal muscle, use the 1.5-inch needle. Before you start, clean the top of the vial with an alcohol swab. Remove the cap from the vial adapter and insert it into the vial."

Answered by AI

Can RISPERDAL CONSTA be given monthly?

"You can gradually increase the dosage of risperidone-SQ over time until you reach a monthly dose of either 90 mg or 120 mg, depending on what is tolerable for you."

Answered by AI

What is the difference between Risperdal and RISPERDAL CONSTA?

"The drugs Risperdal and Risperdal Consta are both antipsychotic drugs prescribed to treat schizophrenia, bipolar mania, and autism. Risperdal Consta is an injectable, long-acting form of risperidone."

Answered by AI

Clinical Trials for Risperdal Consta

Have you considered Risperdal Consta clinical trials? We made a collection of clinical trials featuring Risperdal Consta, we think they might fit your search criteria.
Have you considered Risperdal Consta clinical trials? We made a collection of clinical trials featuring Risperdal Consta, we think they might fit your search criteria.
Have you considered Risperdal Consta clinical trials? We made a collection of clinical trials featuring Risperdal Consta, we think they might fit your search criteria.