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What is Rifadin
RifampicinThe Generic name of this drug
Treatment SummaryRifampin is an antibiotic derived from Streptomyces mediterranei. It works by inhibiting the activity of DNA-dependent RNA polymerase, which prevents bacteria from producing new RNA. Rifampin is effective against a wide range of bacteria, including certain forms of Mycobacterium, and can be used to eliminate both intracellular and extracellular organisms.
Rifadinis the brand name
Rifadin Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Rifadin
Rifampicin
1971
75
Approved as Treatment by the FDA
Rifampicin, otherwise known as Rifadin, is approved by the FDA for 3 uses which include initial phase Tuberculosis and late phase Tuberculosis .initial phase Tuberculosis
Used to treat initial phase Tuberculosis in combination with Isoniazid
late phase Tuberculosis
Used to treat late phase Tuberculosis in combination with Isoniazid
Nasopharynx
Effectiveness
How Rifadin Affects PatientsRifampin is a type of antibiotic that stops bacteria from making copies of itself. It is very effective against a wide range of bacteria, including some that cause tuberculosis. It is usually taken orally and is absorbed quickly. It is broken down in the liver and then released in bile and urine. Generally, no changes to the dosage are necessary for people with kidney problems.
How Rifadin works in the bodyRifampin stops cells from making new RNA, which causes them to die.
When to interrupt dosage
The measure of Rifadin is contingent upon the specified condition, including antibacterial therapy, Prosthetic Joint Infections and Nasopharynx. The amount of dosage fluctuates, in accordance with the approach of delivery outlined in the table beneath.Condition
Dosage
Administration
Pruritus
60.0 mg/mL, , 300.0 mg, 120.0 mg, 150.0 mg, 600.0 mg, 450.0 mg
, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Intravenous, Oral, Capsule, Capsule - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, coated - Oral, Capsule, coated, Tablet, Tablet - Oral
Nasopharynx
60.0 mg/mL, , 300.0 mg, 120.0 mg, 150.0 mg, 600.0 mg, 450.0 mg
, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Intravenous, Oral, Capsule, Capsule - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, coated - Oral, Capsule, coated, Tablet, Tablet - Oral
late phase Tuberculosis
60.0 mg/mL, , 300.0 mg, 120.0 mg, 150.0 mg, 600.0 mg, 450.0 mg
, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Intravenous, Oral, Capsule, Capsule - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, coated - Oral, Capsule, coated, Tablet, Tablet - Oral
antibacterial therapy
60.0 mg/mL, , 300.0 mg, 120.0 mg, 150.0 mg, 600.0 mg, 450.0 mg
, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Intravenous, Oral, Capsule, Capsule - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, coated - Oral, Capsule, coated, Tablet, Tablet - Oral
MRSA Infections
60.0 mg/mL, , 300.0 mg, 120.0 mg, 150.0 mg, 600.0 mg, 450.0 mg
, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Intravenous, Oral, Capsule, Capsule - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, coated - Oral, Capsule, coated, Tablet, Tablet - Oral
Prosthetic Joint Infections
60.0 mg/mL, , 300.0 mg, 120.0 mg, 150.0 mg, 600.0 mg, 450.0 mg
, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Intravenous, Oral, Capsule, Capsule - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, coated - Oral, Capsule, coated, Tablet, Tablet - Oral
initial phase Tuberculosis
60.0 mg/mL, , 300.0 mg, 120.0 mg, 150.0 mg, 600.0 mg, 450.0 mg
, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Intravenous, Oral, Capsule, Capsule - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, coated - Oral, Capsule, coated, Tablet, Tablet - Oral
Warnings
Rifadin has five contraindications and should not be employed if you suffer from any of the conditions in the following table.Rifadin ContraindicationsCondition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Common Rifadin Drug Interactions
Drug Name
Risk Level
Description
1,2-Benzodiazepine
Major
The metabolism of 1,2-Benzodiazepine can be increased when combined with Rifampicin.
3,5-diiodothyropropionic acid
Major
The metabolism of 3,5-diiodothyropropionic acid can be increased when combined with Rifampicin.
5-androstenedione
Major
The metabolism of 5-androstenedione can be increased when combined with Rifampicin.
6-O-benzylguanine
Major
The metabolism of 6-O-benzylguanine can be increased when combined with Rifampicin.
7-ethyl-10-hydroxycamptothecin
Major
The metabolism of 7-ethyl-10-hydroxycamptothecin can be increased when combined with Rifampicin.
Rifadin Toxicity & Overdose RiskThe lowest toxic dose of this drug in rats has been found to be 1570mg/kg. Prolonged exposure to this drug may cause nausea, vomiting, and loss of consciousness.
Rifadin Novel Uses: Which Conditions Have a Clinical Trial Featuring Rifadin?
Currently, there are 5 active studies evaluating the potential of Rifadin in ameliorating late-stage Tuberculosis, initial-phase Tuberculosis and Pruritus.Condition
Clinical Trials
Trial Phases
late phase Tuberculosis
0 Actively Recruiting
Prosthetic Joint Infections
4 Actively Recruiting
Phase 4, Not Applicable
Nasopharynx
0 Actively Recruiting
antibacterial therapy
0 Actively Recruiting
Pruritus
0 Actively Recruiting
MRSA Infections
0 Actively Recruiting
initial phase Tuberculosis
0 Actively Recruiting
Rifadin Reviews: What are patients saying about Rifadin?
5Patient Review
4/28/2011 The antibiotic really helped me with my MRSA infection. The main side effects are an upset stomach and decreased appetite, but these were tolerable. Another interesting effect was that my urine looked like Tang or orange Kool-Aid.
1.7Patient Review
1/20/2012 I had to stop taking this medication because of all the negative side effects I experienced.
Patient Q&A Section about rifadin
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What type of drug is Rifadin?
"Rifadin is a prescription medicine used to treat the symptoms of Tuberculosis. It may be used alone or with other medications. Rifadin belongs to a class of drugs called Antitubercular Agents."
Answered by AI
Is Rifadin the same as rifampin?
"Rifampin is a good antibiotic to use to treat active and latent tuberculosis, as well as to prevent serious meningococcal infections. However, it can change the color of your teeth and body fluids."
Answered by AI
What does rifampin do to your body?
"Rifampin is an antibiotic that kills the bacteria that cause infection. It will not work for colds, flu, or other viral infections."
Answered by AI
What is Rifadin used for?
"The Rifadin 300mg Capsule is used to treat bacterial infections such as tuberculosis, leprosy, and brucellosis. It is typically used in conjunction with other medications."
Answered by AI