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What is Ridaura
AuranofinThe Generic name of this drug
Treatment SummaryAuranofin is a type of gold salt that works to reduce inflammation and increase immunity. It is used to treat rheumatic diseases, and works by increasing the levels of heme oxygenase 1 (HO-1). HO-1 is an enzyme with anti-inflammatory qualities that helps to reduce the symptoms of rheumatic diseases.
Ridaurais the brand name
Ridaura Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Ridaura
Auranofin
1985
2
Approved as Treatment by the FDA
Auranofin, otherwise known as Ridaura, is approved by the FDA for 1 uses including Rheumatoid Arthritis .Rheumatoid Arthritis
Helps manage Rheumatoid Arthritis
Effectiveness
How Ridaura Affects PatientsAuranofin is a type of drug made from gold and is used to treat inflammatory arthritis. It is usually used when other treatments, such as NSAIDs and corticosteroids, have not worked.
How Ridaura works in the bodyAuranofin is used to treat rheumatoid arthritis, a condition that causes swelling, warmth, and pain in the joints. It works by preventing the body from releasing antibodies and enzymes that cause inflammation. Auranofin also has effects on an enzyme called thioredoxin reductase, which helps control free radicals. When auranofin stops the enzyme from working, it increases the amount of free radicals, which can lead to cell death. Auranofin can also cause T-cell activation, which can help fight tumors.
When to interrupt dosage
The suggested dosage of Ridaura is contingent upon the recognized condition. The measure of dosage is contingent upon the technique of delivery (e.g. Oral or Capsule) featured in the table beneath.Condition
Dosage
Administration
Rheumatoid Arthritis
, 3.0 mg
Oral, , Capsule, Capsule - Oral
Warnings
Ridaura ContraindicationsCondition
Risk Level
Notes
Pulmonary Fibrosis caused by gold
Do Not Combine
Anaphylactic shock
Do Not Combine
Necrotizing Enterocolitis
Do Not Combine
Exfoliative dermatitis caused by gold
Do Not Combine
severe hematologic disorder caused by gold
Do Not Combine
Bone Marrow
Do Not Combine
Common Ridaura Drug Interactions
Drug Name
Risk Level
Description
Abacavir
Minor
Auranofin may decrease the excretion rate of Abacavir which could result in a higher serum level.
Aclidinium
Minor
Auranofin may decrease the excretion rate of Aclidinium which could result in a higher serum level.
Acrivastine
Minor
Auranofin may decrease the excretion rate of Acrivastine which could result in a higher serum level.
Albutrepenonacog alfa
Minor
Auranofin may decrease the excretion rate of Albutrepenonacog alfa which could result in a higher serum level.
Allylestrenol
Minor
Auranofin may decrease the excretion rate of Allylestrenol which could result in a higher serum level.
Ridaura Toxicity & Overdose RiskThe lowest toxic dose of this drug in rats is greater than 2000mg/kg. Overdosing on this drug may cause diarrhea, vomiting, stomach pain, and signs of an allergic reaction like skin rash, hives, itching, and difficulty breathing.
Ridaura Novel Uses: Which Conditions Have a Clinical Trial Featuring Ridaura?
75 active clinical trials are assessing the potential of Ridaura in providing relief for Rheumatoid Arthritis.Condition
Clinical Trials
Trial Phases
Rheumatoid Arthritis
61 Actively Recruiting
Not Applicable, Phase 4, Phase 3, Phase 2, Phase 1
Ridaura Reviews: What are patients saying about Ridaura?
5Patient Review
5/15/2011 This drug, in addition to an NSAID, has worked well for me. The only downside is that it has caused some irritation in my lungs because of my COPD.
4.7Patient Review
9/5/2009 After trying several different medications, Ridaura has given me the best relief from my RA symptoms. It is easy to take and I am very pleased with the results.
Patient Q&A Section about ridaura
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Who manufactures ridaura?
"(n.d.). Retrieved March 04, 2020, from https://www.ema.europa.eu/en/medicines/human/EPAR/ridaura
This is the European Public Assessment Report for Ridaura capsules. They are used to treat rheumatoid arthritis. The capsules contain 3 mg of the active substance auranofin."
Answered by AI
What is ridaura used for?
"This drug is one part of a larger treatment plan for active rheumatoid arthritis that also includes non-drug therapies like rest and physical therapy. It's for people with severe rheumatoid arthritis who haven't had success with other drugs or can't take them."
Answered by AI
What is an adverse effect of auranofin?
"Auranofin may cause diarrhea, itching, skin rash, mouth inflammation, loose stools, nausea, and vomiting."
Answered by AI
Is ridaura available in the US?
"Auranofin is a compound containing gold that is used to treat arthritis. It is available as a capsule that is taken by mouth."
Answered by AI