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What is Restoril
TemazepamThe Generic name of this drug
Treatment SummaryTemazepam is a medication often used to treat insomnia. It works by calming the brain and nervous system, and is sometimes prescribed to help relax the muscles. Temazepam is one of the most commonly prescribed medications around the world, but it has a high potential for misuse and can lead to addiction if not taken as prescribed. The US military uses temazepam as a sedative-hypnotic for soldiers and pilots to get adequate rest. It was first synthesized in 1965 and became widely available for civilian use soon after.
Restorilis the brand name
Restoril Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Restoril
Temazepam
1981
193
Approved as Treatment by the FDA
Temazepam, also called Restoril, is approved by the FDA for 1 uses like Insomnia .Insomnia
Used to treat Insomnia in combination with Choline
Effectiveness
How Restoril Affects PatientsTemazepam is a type of medication used to treat insomnia. It works by calming the central nervous system and increasing the amount of a chemical called GABA, which helps reduce anxiety and produce sleep. Clinical studies have shown that taking temazepam can help people fall asleep faster and sleep more deeply. However, it can cause rebound insomnia when the drug is stopped, and long-term use may lead to tolerance and dependence. The length of time temazepam works for and any side effects may depend on how quickly the body processes and eliminates the drug, so people taking it should be aware of the possibility of increased wakefulness and
How Restoril works in the bodyGABA is the main chemical that inhibits neuron activity in the body. When GABA binds to receptors in neuron synapses, it causes chloride ions to enter the cell, making it harder for the neuron to fire. Temazepam works by increasing the effects of GABA by making it easier for GABA to bind to its receptor. This increased binding of GABA to its receptor causes more chloride to enter the cell, further reducing neuron activity. This can result in sedation, relaxation of muscles, prevention of seizures, and reduced anxiety.
When to interrupt dosage
The prescribed measurement of Restoril is determined by the identified affliction. The amount of dosage is contingent upon the procedure of delivery (e.g. Capsule or Capsule - Oral) listed in the table below.Condition
Dosage
Administration
Insomnia
15.0 mg, 7.5 mg, , 30.0 mg, 22.5 mg, 10.0 mg, 20.0 mg
, Oral, Capsule, Capsule - Oral, Kit, Tablet, Tablet - Oral
Warnings
Restoril has one contraindication, thus it should not be taken if you experience any of the conditions highlighted in the table below.Restoril ContraindicationsCondition
Risk Level
Notes
suspected pregnancy
Do Not Combine
Common Restoril Drug Interactions
Drug Name
Risk Level
Description
Azelastine
Major
Temazepam may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Deutetrabenazine
Major
The risk or severity of sedation and somnolence can be increased when Temazepam is combined with Deutetrabenazine.
Ethanol
Major
Temazepam may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Methadone
Major
Temazepam may increase the central nervous system depressant (CNS depressant) activities of Methadone.
Oliceridine
Major
The risk or severity of hypotension, sedation, death, somnolence, and respiratory depression can be increased when Temazepam is combined with Oliceridine.
Restoril Toxicity & Overdose RiskTaking too much temazepam can cause drowsiness, confusion, and even coma. Severe overdoses could lead to breathing problems, low blood pressure, and ultimately, death. Benzodiazepines like temazepam can cause harm to unborn babies, so pregnant women should not take it. Temazepam is not known to be passed through breast milk. The drug has not been tested for safety or effectiveness in children and lower doses are recommended for seniors to avoid over-sedation, dizziness, confusion, and falls. Animal studies did not show any signs of cancer, but female mice had abnormal liver growths at
Restoril Novel Uses: Which Conditions Have a Clinical Trial Featuring Restoril?
Currently, 81 active trials are being conducted to analyze the potential of Restoril in managing Insomnia.Condition
Clinical Trials
Trial Phases
Insomnia
93 Actively Recruiting
Phase 4, Not Applicable, Phase 2, Phase 3, Phase 1, Early Phase 1
Restoril Reviews: What are patients saying about Restoril?
5Patient Review
2/12/2015 Restoril has been extremely effective in treating my depression and anxiety, with no negative side effects that I have experienced.
5Patient Review
12/12/2017 I've had insomnia for years, and this is the only thing that's really helped me get some rest. I'm older now and can't go without it.
4.3Patient Review
11/8/2021 Out of all the sleep medications I've tried, 30mg of Restoril has been the most effective for me. It's not perfect, but it does help me get to sleep most nights.
4Patient Review
6/9/2019 This treatment has definitely saved my life, but I find that I need a nap every day now. Not sure if that's related, but it's worth noting. I've been on the treatment for about three months and have had no problems skipping a night here or there.
3.7Patient Review
5/30/2015 Restoril is only effective if you don't use it every night, according to my doctor. It's for short-term use only. I've heard similar things about Dramamine. That said, it's still nice to have something for the occasional sleepless night.
2.7Patient Review
9/2/2015 I've had trouble sleeping for the past few months. I got temazepan 15's and 1 pill before bedtime worked fine. Then shortly 1 pill wasn't doing anything so I took 2. After a bottle it wasn't working so I bumped up to the 30 mg. that worked a few days but now it's taking 3-4 30mg to knock me out. I sleep deeply for about 6 hours but then any sound immediately wakes me up and that's it. I'm up til the next night. Is this normal?
2.3Patient Review
3/2/2016 The dosage on this is really hard to get right.
2.3Patient Review
11/29/2019 I tried this for the first time after not sleeping for two days and it was awful. I woke up frequently, my heart was racing, and I had severe leg cramps. There's no way I'm taking it again.
2.3Patient Review
3/29/2021 I've been struggling with chronic insomnia for a while now, and I've tried so many different medications. Unfortunately, I only get about three nights of sleep per week even taking the maximum recommended dosage of 15mg. My doctor wanted me to increase my dosage to 30mg, but my body just couldn't handle it. I would love to find a more natural sleep aid that is less harsh on the body and has fewer side effects, but so far nothing has worked for me.
2.3Patient Review
11/28/2020 Restoril was ineffective for me.
2.3Patient Review
1/8/2022 The medication kept me up all night. I took my first dose at 10 pm and was awake until 2 am before finally falling asleep. However, I was only able to sleep for less than 30 minutes before being woken up again. This pattern continued throughout the night until I gave up and got out of bed at 6 am.
2.3Patient Review
11/18/2021 I took one pill, and after an hour I fell asleep for about three hours. Then, I took another pill but didn't notice any effects even after lying down for two more hours. All in all, it's been about 72 hours since I've taken this medication and I've only gotten a total of three hours of sleep.
2Patient Review
8/3/2022 I took this medication for a few months with no success. I was up all night and felt just as exhausted the next day. Definitely not recommended. Ambien worked best for me, but I can't get it prescribed anymore.
1Patient Review
5/4/2016 I took Restoril once and it did nothing but make me feel drowsy for a few hours. I then experienced sudden loss of balance and fell, hitting my head in the process. Needless to say, I haven't taken it since.
1Patient Review
3/6/2016 I wake up with headaches, dark eye circles, and feeling agitated after taking this medication. It's not worth it for the supposed six to eight hours of sleep.
Patient Q&A Section about restoril
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is Restoril an opioid?
"If you're taking RESTORIL, avoid taking opioids, alcohol, or other central nervous system depressants as they can cause drowsiness, breathing problems, coma, and death."
Answered by AI
Is Restoril a good sleeping pill?
"Temazepam may help you fall asleep more quickly, sleep for longer periods, and wake up less often during the night, so you can get a better night's sleep. It belongs to a class of drugs called benzodiazepines, which act on your brain to produce a calming effect."
Answered by AI
Is Restoril the same as Ambien?
"They work by depressing the central nervous system to help you sleep.
Are Restoril and Ambien the same thing?
No, they are not the same thing. Restoril is a benzodiazepine and Ambien is a type A GABA receptor agonist. They both work by depressing the central nervous system to help you sleep, but they are different types of sedatives."
Answered by AI