Restoril

Insomnia

Treatment

1 FDA approval

0 Active Studies for Restoril

What is Restoril

Temazepam

The Generic name of this drug

Treatment Summary

Temazepam is a medication often used to treat insomnia. It works by calming the brain and nervous system, and is sometimes prescribed to help relax the muscles. Temazepam is one of the most commonly prescribed medications around the world, but it has a high potential for misuse and can lead to addiction if not taken as prescribed. The US military uses temazepam as a sedative-hypnotic for soldiers and pilots to get adequate rest. It was first synthesized in 1965 and became widely available for civilian use soon after.

Restoril

is the brand name

image of different drug pills on a surface

Restoril Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Restoril

Temazepam

1981

193

Approved as Treatment by the FDA

Temazepam, also called Restoril, is approved by the FDA for 1 uses like Insomnia .

Insomnia

Used to treat Insomnia in combination with Choline

Effectiveness

How Restoril Affects Patients

Temazepam is a type of medication used to treat insomnia. It works by calming the central nervous system and increasing the amount of a chemical called GABA, which helps reduce anxiety and produce sleep. Clinical studies have shown that taking temazepam can help people fall asleep faster and sleep more deeply. However, it can cause rebound insomnia when the drug is stopped, and long-term use may lead to tolerance and dependence. The length of time temazepam works for and any side effects may depend on how quickly the body processes and eliminates the drug, so people taking it should be aware of the possibility of increased wakefulness and

How Restoril works in the body

GABA is the main chemical that inhibits neuron activity in the body. When GABA binds to receptors in neuron synapses, it causes chloride ions to enter the cell, making it harder for the neuron to fire. Temazepam works by increasing the effects of GABA by making it easier for GABA to bind to its receptor. This increased binding of GABA to its receptor causes more chloride to enter the cell, further reducing neuron activity. This can result in sedation, relaxation of muscles, prevention of seizures, and reduced anxiety.

When to interrupt dosage

The prescribed measurement of Restoril is determined by the identified affliction. The amount of dosage is contingent upon the procedure of delivery (e.g. Capsule or Capsule - Oral) listed in the table below.

Condition

Dosage

Administration

Insomnia

15.0 mg, 7.5 mg, , 30.0 mg, 22.5 mg, 10.0 mg, 20.0 mg

, Capsule, Oral, Capsule - Oral, Kit, Tablet, Tablet - Oral

Warnings

Restoril has one contraindication, thus it should not be taken if you experience any of the conditions highlighted in the table below.

Restoril Contraindications

Condition

Risk Level

Notes

suspected pregnancy

Do Not Combine

There are 20 known major drug interactions with Restoril.

Common Restoril Drug Interactions

Drug Name

Risk Level

Description

Azelastine

Major

Temazepam may increase the central nervous system depressant (CNS depressant) activities of Azelastine.

Deutetrabenazine

Major

The risk or severity of sedation and somnolence can be increased when Temazepam is combined with Deutetrabenazine.

Ethanol

Major

Temazepam may increase the central nervous system depressant (CNS depressant) activities of Ethanol.

Methadone

Major

Temazepam may increase the central nervous system depressant (CNS depressant) activities of Methadone.

Oliceridine

Major

The risk or severity of hypotension, sedation, death, somnolence, and respiratory depression can be increased when Temazepam is combined with Oliceridine.

Restoril Toxicity & Overdose Risk

Taking too much temazepam can cause drowsiness, confusion, and even coma. Severe overdoses could lead to breathing problems, low blood pressure, and ultimately, death. Benzodiazepines like temazepam can cause harm to unborn babies, so pregnant women should not take it. Temazepam is not known to be passed through breast milk. The drug has not been tested for safety or effectiveness in children and lower doses are recommended for seniors to avoid over-sedation, dizziness, confusion, and falls. Animal studies did not show any signs of cancer, but female mice had abnormal liver growths at

image of a doctor in a lab doing drug, clinical research

Restoril Novel Uses: Which Conditions Have a Clinical Trial Featuring Restoril?

Currently, 81 active trials are being conducted to analyze the potential of Restoril in managing Insomnia.

Condition

Clinical Trials

Trial Phases

Insomnia

0 Actively Recruiting

Restoril Reviews: What are patients saying about Restoril?

5

Patient Review

2/12/2015

Restoril for Chronic Trouble Sleeping

Restoril has been extremely effective in treating my depression and anxiety, with no negative side effects that I have experienced.

5

Patient Review

12/12/2017

Restoril for Chronic Trouble Sleeping

I've had insomnia for years, and this is the only thing that's really helped me get some rest. I'm older now and can't go without it.

4.3

Patient Review

11/8/2021

Restoril for Chronic Trouble Sleeping

Out of all the sleep medications I've tried, 30mg of Restoril has been the most effective for me. It's not perfect, but it does help me get to sleep most nights.

4

Patient Review

6/9/2019

Restoril for Chronic Trouble Sleeping

This treatment has definitely saved my life, but I find that I need a nap every day now. Not sure if that's related, but it's worth noting. I've been on the treatment for about three months and have had no problems skipping a night here or there.

3.7

Patient Review

5/30/2015

Restoril for Chronic Trouble Sleeping

Restoril is only effective if you don't use it every night, according to my doctor. It's for short-term use only. I've heard similar things about Dramamine. That said, it's still nice to have something for the occasional sleepless night.

2.7

Patient Review

9/2/2015

Restoril for Chronic Trouble Sleeping

I've had trouble sleeping for the past few months. I got temazepan 15's and 1 pill before bedtime worked fine. Then shortly 1 pill wasn't doing anything so I took 2. After a bottle it wasn't working so I bumped up to the 30 mg. that worked a few days but now it's taking 3-4 30mg to knock me out. I sleep deeply for about 6 hours but then any sound immediately wakes me up and that's it. I'm up til the next night. Is this normal?

2.3

Patient Review

3/2/2016

Restoril for Chronic Trouble Sleeping

The dosage on this is really hard to get right.

2.3

Patient Review

11/29/2019

Restoril for Chronic Trouble Sleeping

I tried this for the first time after not sleeping for two days and it was awful. I woke up frequently, my heart was racing, and I had severe leg cramps. There's no way I'm taking it again.

2.3

Patient Review

3/29/2021

Restoril for Chronic Trouble Sleeping

I've been struggling with chronic insomnia for a while now, and I've tried so many different medications. Unfortunately, I only get about three nights of sleep per week even taking the maximum recommended dosage of 15mg. My doctor wanted me to increase my dosage to 30mg, but my body just couldn't handle it. I would love to find a more natural sleep aid that is less harsh on the body and has fewer side effects, but so far nothing has worked for me.

2.3

Patient Review

11/28/2020

Restoril for Chronic Trouble Sleeping

Restoril was ineffective for me.

2.3

Patient Review

1/8/2022

Restoril for Chronic Trouble Sleeping

The medication kept me up all night. I took my first dose at 10 pm and was awake until 2 am before finally falling asleep. However, I was only able to sleep for less than 30 minutes before being woken up again. This pattern continued throughout the night until I gave up and got out of bed at 6 am.

2.3

Patient Review

11/18/2021

Restoril for Chronic Trouble Sleeping

I took one pill, and after an hour I fell asleep for about three hours. Then, I took another pill but didn't notice any effects even after lying down for two more hours. All in all, it's been about 72 hours since I've taken this medication and I've only gotten a total of three hours of sleep.

2

Patient Review

8/3/2022

Restoril for Chronic Trouble Sleeping

I took this medication for a few months with no success. I was up all night and felt just as exhausted the next day. Definitely not recommended. Ambien worked best for me, but I can't get it prescribed anymore.

1

Patient Review

5/4/2016

Restoril for Chronic Trouble Sleeping

I took Restoril once and it did nothing but make me feel drowsy for a few hours. I then experienced sudden loss of balance and fell, hitting my head in the process. Needless to say, I haven't taken it since.

1

Patient Review

3/6/2016

Restoril for Chronic Trouble Sleeping

I wake up with headaches, dark eye circles, and feeling agitated after taking this medication. It's not worth it for the supposed six to eight hours of sleep.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about restoril

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Restoril an opioid?

"If you're taking RESTORIL, avoid taking opioids, alcohol, or other central nervous system depressants as they can cause drowsiness, breathing problems, coma, and death."

Answered by AI

Is Restoril used for anxiety?

"Restoril is the brand name for Temazepam, a Benzodiazepine which treats insomnia. It is a drug which helps people fall asleep faster and sleep through the night. For some patients, Restoril also treats anxiety, muscle spasms, and epileptic seizures."

Answered by AI

Is Restoril a good sleeping pill?

"Temazepam may help you fall asleep more quickly, sleep for longer periods, and wake up less often during the night, so you can get a better night's sleep. It belongs to a class of drugs called benzodiazepines, which act on your brain to produce a calming effect."

Answered by AI

Is Restoril the same as Ambien?

"They work by depressing the central nervous system to help you sleep.

Are Restoril and Ambien the same thing?

No, they are not the same thing. Restoril is a benzodiazepine and Ambien is a type A GABA receptor agonist. They both work by depressing the central nervous system to help you sleep, but they are different types of sedatives."

Answered by AI