Your session is about to expire
What is Razadyne
GalantamineThe Generic name of this drug
Treatment SummaryGalantamine is a medication used to treat mild to moderate Alzheimer’s disease. It works by blocking an enzyme that breaks down the neurotransmitter acetylcholine, which helps to improve cholinergic neuron function and communication in the brain. Galantamine does not slow the progression of Alzheimer’s but can improve symptoms. It is sold under the brand name Razadyne and comes in tablets, capsules or liquid form.
Razadyneis the brand name
Razadyne Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Razadyne
Galantamine
2001
94
Effectiveness
How Razadyne Affects PatientsGalantamine is a drug that helps to increase the amount of a chemical in the body called acetylcholine. This chemical helps the brain and muscles send signals, so increasing it can help improve cognition, daily activities, and behavior in people with dementia. While it can't cure dementia, it may improve symptoms for a short period of time. Galantamine has also been shown to reverse a type of drug-induced confusion called anticholinergic syndrome.
How Razadyne works in the bodyAlzheimer’s disease is a serious degenerative disorder that causes memory loss, cognitive decline and the buildup of toxic proteins. Galantamine is an effective treatment for Alzheimer’s because it helps to restore the levels of acetylcholine in the brain. Acetylcholine is a key neurotransmitter involved in memory, attention, learning, and other vital functions. Galantamine blocks an enzyme called acetylcholinesterase which breaks down acetylcholine in the brain. This helps to increase acetylcholine levels, which can help improve memory and cognitive function. Galantamine also binds to nicotin
When to interrupt dosage
The endorsed dosage of Razadyne relies upon the diagnosed circumstance, for example, mild Dementia of the Alzheimer's Type, Alzheimer's Disease and Cerebrovascular Diseases. The amount of dosage may differ, as per the method of administration featured in the following table.Condition
Dosage
Administration
mild Dementia of the Alzheimer's Type
, 8.0 mg, 16.0 mg, 24.0 mg, 4.0 mg, 12.0 mg, 4.0 mg/mL
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral
Alzheimer's Disease
, 8.0 mg, 16.0 mg, 24.0 mg, 4.0 mg, 12.0 mg, 4.0 mg/mL
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral
Alzheimer's Disease
, 8.0 mg, 16.0 mg, 24.0 mg, 4.0 mg, 12.0 mg, 4.0 mg/mL
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral
Alzheimer's Disease
, 8.0 mg, 16.0 mg, 24.0 mg, 4.0 mg, 12.0 mg, 4.0 mg/mL
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral
Cerebrovascular Diseases
, 8.0 mg, 16.0 mg, 24.0 mg, 4.0 mg, 12.0 mg, 4.0 mg/mL
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral
Warnings
Razadyne has one counter-indication, so it should not be taken alongside the conditions in the subsequent table.Razadyne ContraindicationsCondition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Galantamine may interact with Pulse Frequency
Common Razadyne Drug Interactions
Drug Name
Risk Level
Description
Amitriptyline
Major
The metabolism of Amitriptyline can be decreased when combined with Galantamine.
Amoxapine
Major
The metabolism of Amoxapine can be decreased when combined with Galantamine.
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Galantamine.
Clomipramine
Major
The metabolism of Clomipramine can be decreased when combined with Galantamine.
Clonidine
Major
The metabolism of Clonidine can be decreased when combined with Galantamine.
Razadyne Toxicity & Overdose RiskThe highest dose of galantamine hydrobromide that has been found to be toxic in rats is 75mg/kg. Overdosing on galantamine can lead to symptoms associated with cholinergic crisis, such as nausea, vomiting, cramping, sweating, slow heart rate, low blood pressure, difficulty breathing, and seizures. Hallucinations have also been reported in some cases. To treat the overdose, supportive care and atropine can be used to reduce the cholinergic effects. Dialysis is not known to be effective for removing galantamine from the bloodstream.
Razadyne Novel Uses: Which Conditions Have a Clinical Trial Featuring Razadyne?
42 active clinical trials are in progress to assess the potential of Razadyne in managing Alzheimer's Disease, Alzheimer's Disease and Alzheimer's Disease.Condition
Clinical Trials
Trial Phases
mild Dementia of the Alzheimer's Type
0 Actively Recruiting
Alzheimer's Disease
0 Actively Recruiting
Cerebrovascular Diseases
1 Actively Recruiting
Not Applicable
Alzheimer's Disease
41 Actively Recruiting
Phase 2, Phase 3, Phase 4, Not Applicable, Phase 1
Alzheimer's Disease
2 Actively Recruiting
Phase 3, Phase 2
Razadyne Reviews: What are patients saying about Razadyne?
5Patient Review
3/15/2009 My memory has stayed intact after using this treatment, which is amazing. I can remember tiny details from years ago vividly, but unfortunately I still have some trouble with more recent things like where I put my keys.
5Patient Review
2/5/2011 This treatment is amazing. It has helped me so much and I would recommend it to anyone.
5Patient Review
11/23/2008 I unfortunately haven't seen any improvement in my mom's condition.
4.7Patient Review
8/8/2010 This client lives in a memory care unit and has not had any side effects from this medication. However, when the dosage was decreased dramatically, the client's behaviors increased. They began refusing care and became more agitated. Sometimes we don't know how well a drug is working until the dosage is lowered or discontinued. In this case, it appears that the medication works very well for this client.
4.3Patient Review
10/22/2009 My husband has been on this medication for six months now with no improvement. The only thing he seems to want to do is sleep. The doctor is increasing the dosage to 24 mg daily, but he's having issues with bloating and gas.
3.7Patient Review
6/24/20083.3Patient Review
6/2/2009 It took my husband four months to see results from this treatment, but it was well worth the wait. He's back to his old self again and we couldn't be happier.
3Patient Review
3/15/2010 This treatment really helped me. I'm grateful for modern medicine.
2.7Patient Review
5/24/20082.3Patient Review
7/6/2009 I have not started taking the medicine yet.
2Patient Review
7/26/2009 This medication caused me to have an irregular heartbeat.
1.7Patient Review
11/15/2008 It's been tough for me to get a handle on what foods work best for my stomach. If I don't eat anything, then my stomach is fine but I lose too much weight. Right now, the best solution seems to be eating lots of water and unprocessed food; however, this leaves me feeling tired. Canned soups and frozen dinners give me nausea and an upset stomach. Surprisingly, greasy food like sausage and cheap frozen pizza make me feel the best.
1.7Patient Review
9/16/2009 My aunt has been taking this medication for 8 months now and we have not seen any improvement in her memory.
1.7Patient Review
5/28/2009 I don't really know what this treatment is supposed to do, but it didn't do anything for me.
1Patient Review
2/20/2009 My mom was given this medication to try and improve her memory, but instead we saw no change. She did experience a lot of fatigue, though, and after six months had a seizure. Since she's stopped taking the medication, her energy has returned but there's been no change in her memory.
1Patient Review
7/16/2010 The severe side effects of this treatment are not worth the benefits. I would rather suffer from Alzheimer's disease than deal with the constant stomach pain, nausea, and diarrhea caused by this medication.
1Patient Review
10/28/2009 The side effects of this medication were really severe. I felt so nauseous, dizzy and tired that I couldn't function normally. My thinking was also impaired, but it got better after I stopped taking the medication.
1Patient Review
10/8/2008Patient Q&A Section about razadyne
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is Razadyne used for?
"Galantamine is a drug that is used to treat mild to moderate confusion that is related to Alzheimer's disease. It does not completely cure Alzheimer's disease, but it may improve memory, awareness, and the ability to perform daily activities."
Answered by AI
What drug class is Razadyne?
"The drug Razadyne ER is a type of medication known as an acetylcholinesterase inhibitor that specifically works on the central nervous system."
Answered by AI
What are the side effects of galantamine?
"The following are symptoms of nausea: vomiting, diarrhea, loss of appetite, stomach pain, heartburn, weight loss, and extreme tiredness."
Answered by AI
Does Razadyne treat Alzheimer's?
"AD is a brain disorder that causes changes in memory, thinking, and behavior.
Galantamine is a treatment for Alzheimer's disease that slows the progression of symptoms. It is produced by Janssen. Alzheimer's disease is a brain disorder that causes changes in memory, thinking, and behavior."
Answered by AI