Pulmicort Flexhaler

Proteinuria, Asthma, Itching + 16 more

Treatment

20 Active Studies for Pulmicort Flexhaler

Treatment for

Proteinuria

What is Pulmicort Flexhaler

Budesonide

The Generic name of this drug

Treatment Summary

Budesonide is a steroid medication used to treat inflammation in the lungs and intestines. It is commonly used to treat conditions such as asthma, chronic obstructive pulmonary disease (COPD), Crohn’s disease, and ulcerative colitis. Budesonide was approved by the FDA in 1994 and is available in various forms, such as inhalers, tablets, and suspensions.

Rhinocort

is the brand name

image of different drug pills on a surface

Pulmicort Flexhaler Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Rhinocort

Budesonide

1994

134

Effectiveness

How Pulmicort Flexhaler Affects Patients

Budesonide is a drug used to reduce inflammation in the respiratory and digestive systems. The amount of the drug that needs to be taken varies from person to person and it is generally considered to be very safe. However, people should be aware of the potential risks of taking this drug, such as an increased level of cortisol in the body, as well as a decreased ability of the adrenal glands to produce hormones.

How Pulmicort Flexhaler works in the body

Corticosteroids are medications that reduce inflammation. They work by binding to a receptor and causing changes in gene expression. These changes result in decreased inflammation, decreased cell death, and increased production of anti-inflammatory proteins. Low doses of corticosteroids provide an anti-inflammatory effect, while higher doses are immunosuppressive, meaning they can weaken the immune system. At very high doses, corticosteroids can also affect the mineralocorticoid receptor, causing an increase in sodium levels and a decrease in potassium levels.

When to interrupt dosage

The measure of Pulmicort Flexhaler is contingent upon the diagnosed illness, including Vasomotor Rhinitis, Crohn's Disease and Chronic Obstructive Pulmonary Disease (COPD). Dosage shifts, correlative to the delivery strategy (e.g. Enema; Kit; Tablet - Rectal or Respiratory (inhalation)) specified in the following table.

Condition

Dosage

Administration

Crohn Disease

, 0.25 mg/mL, 0.5 mg/mL, 1.0 mg/mL, 0.09 mg, 0.032 mg, 3.0 mg, 0.18 mg, 0.2 mg, 0.5 mg, 9.0 mg, 28.0 mg, 2.3 mg, 0.08 mg, 0.16 mg, 0.00008 mg/hour, 0.32 mg, 1.0 mg, 6.0 mg, 0.125 mg/mL, 4.0 mg, 0.064 mg/pump actuation, 0.4 mg/pump actuation, 0.1 mg/pump actuation, 2.0 mg/pump actuation, 0.2 mg/pump actuation, 0.182 mg/pump actuation

Respiratory (inhalation), Inhalant, , Inhalant - Respiratory (inhalation), Suspension, Suspension - Respiratory (inhalation), Aerosol, powder, Aerosol, powder - Respiratory (inhalation), Spray, metered, Nasal, Spray, metered - Nasal, Powder - Respiratory (inhalation), Powder, Aerosol, foam, Aerosol, foam - Rectal, Rectal, Capsule, delayed release pellets - Oral, Capsule, delayed release pellets, Tablet, extended release, Tablet, extended release - Oral, Enema; Kit; Tablet, Enema; Kit; Tablet - Rectal, Capsule, extended release - Oral, Capsule, extended release, Capsule, coated pellets - Oral, Nasal; Respiratory (inhalation), Aerosol - Respiratory (inhalation), Aerosol, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Oral, Inhalant - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Powder, metered, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Capsule - Oral, Capsule, Cutaneous, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Kit, Powder, metered - Respiratory (inhalation), Powder - Nasal; Respiratory (inhalation), Aerosol, metered - Nasal, Capsule, coated pellets, Kit - Rectal, Capsule, delayed release - Oral, Capsule, delayed release, Patch - Cutaneous, Patch

Colitis, Collagenous

Proteinuria

Nasal Congestion

Asthma

Itching

Skin Diseases

Acute Coryza

Ulcerative Colitis

Rhinitis, Vasomotor

Nasal Polyps

Crohn's Disease

Eosinophilic Esophagitis

Hypersensitivity

IGA Glomerulonephritis

Sinusitis

Crohn Disease

maintenance therapy

Chronic Obstructive Pulmonary Disease

Warnings

Pulmicort Flexhaler has five contraindications and must not be taken when experiencing any of the conditions listed in the table below.

Pulmicort Flexhaler Contraindications

Condition

Risk Level

Notes

Asthma

Do Not Combine

Severe Hepatic Impairment

Do Not Combine

Status Asthmaticus

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Budesonide may interact with Pulse Frequency

Severe Hypersensitivity Reactions

Do Not Combine

Budesonide may interact with Pulse Frequency

There are 20 known major drug interactions with Pulmicort Flexhaler.

Common Pulmicort Flexhaler Drug Interactions

Drug Name

Risk Level

Description

2-Methoxyethanol

Major

The risk or severity of adverse effects can be increased when Budesonide is combined with 2-Methoxyethanol.

9-(N-methyl-L-isoleucine)-cyclosporin A

Major

The risk or severity of adverse effects can be increased when Budesonide is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.

Abatacept

Major

The risk or severity of adverse effects can be increased when Budesonide is combined with Abatacept.

Abemaciclib

Major

The metabolism of Abemaciclib can be increased when combined with Budesonide.

Abetimus

Major

The risk or severity of adverse effects can be increased when Budesonide is combined with Abetimus.

Pulmicort Flexhaler Toxicity & Overdose Risk

Taking too much corticosteroid medication can lead to an excessive amount of the hormone in the body and suppress the adrenal gland. If this happens, reduce the dosage of corticosteroids until the levels are back to normal. For mice, a 200mg oral dose is fatal for female mice, and a 400mg oral dose is fatal for male mice.

image of a doctor in a lab doing drug, clinical research

Pulmicort Flexhaler Novel Uses: Which Conditions Have a Clinical Trial Featuring Pulmicort Flexhaler?

516 active studies are assessing the potential of Pulmicort Flexhaler for treating Chronic Obstructive Pulmonary Disease (COPD), Ulcerative Colitis and Allergic conditions.

Condition

Clinical Trials

Trial Phases

Asthma

87 Actively Recruiting

Phase 1, Phase 4, Early Phase 1, Not Applicable, Phase 2, Phase 3

Itching

3 Actively Recruiting

Phase 3, Not Applicable

Chronic Obstructive Pulmonary Disease

72 Actively Recruiting

Phase 3, Phase 1, Phase 2, Not Applicable, Early Phase 1, Phase 4

Proteinuria

5 Actively Recruiting

Phase 2, Phase 3, Phase 4, Phase 1

IGA Glomerulonephritis

0 Actively Recruiting

Ulcerative Colitis

17 Actively Recruiting

Phase 3, Phase 2, Phase 1, Not Applicable, Phase 4

Sinusitis

0 Actively Recruiting

Crohn's Disease

53 Actively Recruiting

Phase 1, Phase 2, Not Applicable, Phase 3, Phase 4, Early Phase 1

Hypersensitivity

1 Actively Recruiting

Phase 4

Colitis, Collagenous

0 Actively Recruiting

Skin Diseases

0 Actively Recruiting

maintenance therapy

0 Actively Recruiting

Rhinitis, Vasomotor

1 Actively Recruiting

Not Applicable

Eosinophilic Esophagitis

0 Actively Recruiting

Acute Coryza

0 Actively Recruiting

Crohn Disease

0 Actively Recruiting

Nasal Polyps

0 Actively Recruiting

Crohn Disease

0 Actively Recruiting

Nasal Congestion

0 Actively Recruiting

Pulmicort Flexhaler Reviews: What are patients saying about Pulmicort Flexhaler?

Patient Review

11/19/2011

Pulmicort Flexhaler for Asthma

I have COPD and sleep apnea, and this treatment has drastically improved my quality of life. I no longer wheeze or feel uncomfortable in my chest and throat.

Patient Review

7/4/2012

Pulmicort Flexhaler for Asthma

Worked immediately after the first nebulizer treatment. After 3 years of continuous shortness of breath + constant migraines, I can finally breathe normally again. It took 4 pulmonologists to figure my diagnosis out, but it was worth it in the end!

Patient Review

4/17/2014

Pulmicort Flexhaler for Asthma

I've used Pulmicort for 20 years to manage my asthma, and it's been great! I'm able to go without it during seasons when my asthma is less active. I only use one puff daily most of the year, and can't remember the last time I needed my rescue inhaler.

Patient Review

3/26/2014

Pulmicort Flexhaler for Asthma

After years of struggling to breathe, this drug has allowed me to live a normal life again. I am so grateful for its existence.

Patient Review

5/7/2010

Pulmicort Flexhaler for Severe Chronic Obstructed Lung Disease

Patient Review

10/19/2010

Pulmicort Flexhaler for Asthma

Patient Review

3/3/2014

Pulmicort Flexhaler for Asthma Prevention

Unfortunately, this treatment didn't help my cough or breathing problems at all.

4.3

Patient Review

9/16/2012

Pulmicort Flexhaler for Severe Chronic Obstructed Lung Disease

I'm 60 years old and have been using Pulmicort for about 23 years. I just had my first DEXA scan to check for bone loss, and the results were not good. The technician said that Pulmicort can cause bone loss, and once it happens, there is no reversing it without adding more drugs into the mix (which comes with its own risks). So I'm getting off of Pulmicort as soon as possible. If you're thinking about using this medication, please do your research on the potential side effects first.

4.3

Patient Review

9/4/2015

Pulmicort Flexhaler for Asthma

WARNING! I'm 64 and have severe osteoporosis in my lower back and hips because of the Pulmicort. One asthma doctor warned me to stop taking it about four years ago, but the damage is irreversible.

3.7

Patient Review

12/27/2012

Pulmicort Flexhaler for Severe Chronic Obstructed Lung Disease

I'm dieting and exercising, but I haven't seen any results. I think the inhaler might be to blame.

3.7

Patient Review

9/15/2012

Pulmicort Flexhaler for Severe Chronic Obstructed Lung Disease

My son used this with great success and no negative effects!

3.3

Patient Review

12/9/2014

Pulmicort Flexhaler for Asthma

This drug has helped with my asthma, but unfortunately comes with the side effect of vaginal bleeding. As soon as I stop taking it, the bleeding stops; so, there's no doubt in my mind that this is the cause.

Patient Review

11/23/2011

Pulmicort Flexhaler for Asthma

I'm a 59-year-old woman who started vaginal bleeding after two weeks of taking this medication. I was also given Xopenex HFA, so I'm not sure which is the cause. The bleeding eased off and then stopped, but then it started again. Has anyone else had this experience? My doctor says it's not a side effect.

Patient Review

12/31/2012

Pulmicort Flexhaler for Severe Chronic Obstructed Lung Disease

I had been using Pulmicort through a nebulizer, but I told my consultant last month that I didn't think it was effective. He said it was more of a "placebo" effect, which didn't sit well with me.

Patient Review

10/19/2010

Pulmicort Flexhaler for Asthma

2.7

Patient Review

7/18/2012

Pulmicort Flexhaler for Severe Chronic Obstructed Lung Disease

One hour after taking the medication, I started feeling really sick. I threw up my dinner, got chills and felt like I was going to faint. My throat felt weird and I had a terrible taste in my mouth.

2.3

Patient Review

9/24/2013

Pulmicort Flexhaler for Severe Chronic Obstructed Lung Disease

I'm a bit confused about how to use this properly. I lost the directions, and the instructions from my doctor differed from what was written on the patient information pamphlet.

Patient Review

7/26/2011

Pulmicort Flexhaler for Asthma

Patient Review

10/22/2016

Pulmicort Flexhaler for Asthma

This flexhaler is really complicated and not user friendly. I needed to go back to the doctor just to figure out how to use it, which defeats the purpose of having a medication you can take at home.

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about pulmicort flexhaler

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the Pulmicort Flexhaler used for?

"Pulmicort Flexhaler is a powder inhaled corticosteroid used to treat and prevent symptoms of asthma in adults and children aged 6 and over."

Answered by AI

How often do you use Pulmicort Flexhaler?

"People usually take Pulmicort Flexhaler twice a day, once in the morning and once at night. If you are using Pulmicort Flexhaler, your doctor will let you know how many puffs you need to take for each dose."

Answered by AI

Is Pulmicort Flexhaler a steroid?

"Pulmicort Flexhaler is a type of inhaler that contains a powder form of the steroid budesonide. It is used to prevent asthma attacks by helping to reduce inflammation in the airways."

Answered by AI

What is the difference between Pulmicort and Pulmicort Flexhaler?

"Pulmicort is a good option for controlling and preventing asthma symptoms in children, but it is not a rescue inhaler and requires a jet nebulizer machine. The most effective class of medicines for managing asthma is inhaled corticosteroids, and Pulmicort Flexhaler is a good option for this."

Answered by AI

Clinical Trials for Pulmicort Flexhaler

Have you considered Pulmicort Flexhaler clinical trials?

We made a collection of clinical trials featuring Pulmicort Flexhaler, we think they might fit your search criteria.

Have you considered Pulmicort Flexhaler clinical trials?

We made a collection of clinical trials featuring Pulmicort Flexhaler, we think they might fit your search criteria.

Image of Stanford University in Stanford, United States.

MoblO2 for Chronic Lung Diseases

18+

All Sexes

Stanford, CA

Many patients with chronic lung disease (e.g., chronic obstructive pulmonary disease (COPD) or interstitial lung disease (ILD)) require supplemental oxygen (O2) at some point during their disease course. Practitioners prescribe O2 to patients with chronic lung disease in hopes of the following: 1) that it will limit desaturation events and combat breathlessness, thus preventing the frustratingly slow pace and numerous rest breaks patients are forced to adopt while doing even simple tasks; 2) that it will allow patients to be more active physically (perhaps increase their ability to exercise) and socially (perhaps leave the home more often); 3) that it will stave off putative complications of hypoxemia (e.g., cognitive dysfunction, pulmonary hypertension) and 4) that it will improve health-related quality of life (HRQL). However, despite the rationale for O2, and prescribers' good intentions, patients generally view O2 with frustration and fear - it threatens their HRQL, which is already impaired by having a condition that imposes itself on every aspect of their lives. Nasal cannulas and delivery devices call unwanted attention to patients when they are out in public. O2 users feel stigmatized and are often viewed as "smokers who get what they deserve, even if they never smoked a day in their lives" - or as disabled, sick or even infectious. O2 steals patients' independence, forcing them to plan their lives around it. The anxiety that patients and their caregivers experience around running out of oxygen, or not getting enough, immobilizes them and restricts participation in activities outside of the home. O2 disrupts the home environment, adding stress, and creating a burden for patients' caregiver-loved-ones who are often saddled with the responsibility of ensuring adequate equipment and supply of O2, and O2 is a constant reminder to patients they are living with a condition that could shorten their lives. O2 delivery equipment is typically heavy, unwieldy and intimidating. Different recommendations (e.g., insurance companies use 88% as a cut-off for SpO2, while many practitioners focus on 90%) make it confusing for patients, which almost certainly affects adherence. O2-requiringpatients are starving for things that can make their lives easier. An auto-adjusting O2 delivery device - one that automatically delivers the correct amount of O2 to maintain blood oxygen at desired, pre-set levels - would alleviate the need for patients to constantly (incessantly for many) monitor their peripheral oxygen saturation (SpO2) and adjust O2flow to meet the demands as exertion levels vary . The MoblO2 device is a battery-operated, light-weight, closed-loop O2 delivery device that houses a regulator (which attaches to compressed gas O2 tanks) and adjusts O2 flow to meet a pre-set blood oxygen level. A pulse oximeter is worn on the ear and transmits via Bluetooth to the device, which adjusts an internal valve to control flow on a second-to-second basis. The user sets the dial to the highest flow of O2 needed to meet the demands of activities they might perform (up to 15 liters per minute), and the device adjusts flow, up to the pre-set level to maintain SpO2 at a preset level (e.g., \> 90%). To conserve O2 supply in the tank - and to avoid over-oxygenation (which could be problematic for a small percentage of patients with the most severe COPD) - the MoblO2 begins to limit O2 flow at a SpO2 of 93%. The device can be manually over-ridden by the user, and should the battery run out - or the device fail for some unforeseen reason - the default position is valve open, so the users receive whatever flow of oxygen has been set on the dial. Given the substantial burdens of O2 on patients and their families, the hassles patients describe with having to monitor their SpO2 and repeatedly adjust the flow of O2 to meet their needs, patients and experts around the world have called for improvements in O2 delivery equipment. The MoblO2 is just such a remarkable improvement and a giant step forward in helping to ease the burdens of O2 on patients who require it. The purpose of this study is to investigate the effects of the MoblO2 O2 delivery device on a range of outcomes, including physical activity, amount (liters) O2 use; maintenance of adequate SpO2 levels; patient reported outcomes including symptoms, HRQL and satisfaction with the MoblO2 O2 device.

Waitlist Available

Has No Placebo

Stanford University

Jeff Swigris, DO, MS

Minnesota Health Solutions