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What is Promethegan
PromethazineThe Generic name of this drug
Treatment SummaryPromethazine is a medication developed in 1946 in France and is used to treat a range of symptoms including allergies, pain, sedation, nausea, and vomiting. It works by blocking certain receptors in the body and has been approved by the FDA since 1951.
Phenerganis the brand name
Promethegan Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Phenergan
Promethazine
1951
473
Approved as Treatment by the FDA
Promethazine, otherwise called Phenergan, is approved by the FDA for 6 uses such as Catarrh and upper respiratory symptoms .Catarrh
Used to treat Common Cold in combination with Codeine
upper respiratory symptoms
Used to treat upper respiratory symptoms in combination with Codeine
Nasal Congestion
Used to treat Nasal Congestion in combination with Phenylephrine
Allergic Reaction
Used to treat Allergic Reaction in combination with Codeine
Anaphylaxis
Acute Bronchitis
Used to treat Cough in combination with Dextromethorphan
Effectiveness
How Promethegan Affects PatientsPromethazine is a drug used to reduce pain, induce sedation, and treat allergies. It usually works for 4-6 hours, but can last up to 12 hours. It is important to warn patients about the potential side effects of this drug, which include drowsiness, difficulty breathing, increased risk of seizures, and decreased bone marrow production.
How Promethegan works in the bodyPromethazine works by blocking histamine, dopamine, and other receptors in the body. This helps to relieve allergy symptoms, improve sleep, reduce anxiety, and ease nausea and vomiting.
When to interrupt dosage
The quantity of Promethegan is contingent upon the diagnosed ailment, including Hay Fever, Postoperative Pain and Acute Bronchitis. The extent of dosage is dependent on the mode of delivery as specified in the table beneath.Condition
Dosage
Administration
Anaphylaxis
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
, Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suppository, Rectal, Suppository - Rectal, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Liquid - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Topical, Cream, Cream - Topical
Allergic urticaria
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
, Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suppository, Rectal, Suppository - Rectal, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Liquid - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Topical, Cream, Cream - Topical
upper respiratory symptoms
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
, Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suppository, Rectal, Suppository - Rectal, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Liquid - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Topical, Cream, Cream - Topical
Hay Fever
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
, Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suppository, Rectal, Suppository - Rectal, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Liquid - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Topical, Cream, Cream - Topical
Nasal Congestion
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
, Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suppository, Rectal, Suppository - Rectal, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Liquid - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Topical, Cream, Cream - Topical
acute Allergic Reactions
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
, Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suppository, Rectal, Suppository - Rectal, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Liquid - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Topical, Cream, Cream - Topical
Coughing
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
, Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suppository, Rectal, Suppository - Rectal, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Liquid - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Topical, Cream, Cream - Topical
Catarrh
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
, Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suppository, Rectal, Suppository - Rectal, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Liquid - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Topical, Cream, Cream - Topical
Sedative therapy
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
, Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suppository, Rectal, Suppository - Rectal, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Liquid - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Topical, Cream, Cream - Topical
Analgesics
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
, Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suppository, Rectal, Suppository - Rectal, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Liquid - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Topical, Cream, Cream - Topical
Allergic Reaction
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
, Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suppository, Rectal, Suppository - Rectal, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Liquid - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Topical, Cream, Cream - Topical
Motion Sickness
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
, Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suppository, Rectal, Suppository - Rectal, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Liquid - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Topical, Cream, Cream - Topical
Postoperative Pain
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
, Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suppository, Rectal, Suppository - Rectal, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Liquid - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Topical, Cream, Cream - Topical
Allergic Conjunctivitis (AC)
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
, Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suppository, Rectal, Suppository - Rectal, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Liquid - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Topical, Cream, Cream - Topical
Acute Bronchitis
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
, Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suppository, Rectal, Suppository - Rectal, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Liquid - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Topical, Cream, Cream - Topical
Dermographism
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
, Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suppository, Rectal, Suppository - Rectal, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Liquid - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Topical, Cream, Cream - Topical
Nausea
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
, Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suppository, Rectal, Suppository - Rectal, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Liquid - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Topical, Cream, Cream - Topical
perioperative nausea and vomiting
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
, Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suppository, Rectal, Suppository - Rectal, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Liquid - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Topical, Cream, Cream - Topical
Pain management
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
, Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suppository, Rectal, Suppository - Rectal, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Liquid - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Topical, Cream, Cream - Topical
Vasomotor Rhinitis
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
, Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Suppository, Rectal, Suppository - Rectal, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Liquid - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Topical, Cream, Cream - Topical
Warnings
Promethegan has six contraindications, and its use should be precluded in the presence of any of the conditions specified in the following table.Promethegan ContraindicationsCondition
Risk Level
Notes
subcutaneous route of administration
Do Not Combine
Asthma
Do Not Combine
Pulse Frequency
Do Not Combine
intra-arterial route of administration
Do Not Combine
Comatose
Do Not Combine
lower respiratory tract symptoms
Do Not Combine
Common Promethegan Drug Interactions
Drug Name
Risk Level
Description
Acenocoumarol
Major
The metabolism of Acenocoumarol can be decreased when combined with Promethazine.
Aclidinium
Major
The risk or severity of adverse effects can be increased when Promethazine is combined with Aclidinium.
Amisulpride
Major
Promethazine may increase the antipsychotic activities of Amisulpride.
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Promethazine.
Azelastine
Major
Promethazine may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Promethegan Toxicity & Overdose RiskThe lowest toxic dose of promethazine in rats is 170mg/kg when given intraperitoneally, and 400mg/kg when given subcutaneously. The lowest toxic dose in mice is 160mg/kg intraperitoneally and 240mg/kg subcutaneously, and 255mg/kg orally. Overdosing on promethazine can lead to mild central nervous system and cardiovascular depression, low blood pressure, decreased breathing, loss of consciousness, muscle stiffness, spasms, convulsions, dry mouth, flushing, gastrointestinal symptoms, and fixed, dilated pupils. Treatment for an overdose should include administering activated charcoal
Promethegan Novel Uses: Which Conditions Have a Clinical Trial Featuring Promethegan?
A total of 131 active studies are investigating the potential of Promethegan to provide Allergy Relief, Sedative Therapy and Hay Fever Relief.Condition
Clinical Trials
Trial Phases
Motion Sickness
0 Actively Recruiting
Sedative therapy
0 Actively Recruiting
acute Allergic Reactions
0 Actively Recruiting
Allergic Conjunctivitis (AC)
1 Actively Recruiting
Phase 2
Catarrh
2 Actively Recruiting
Phase 2, Not Applicable
Acute Bronchitis
12 Actively Recruiting
Phase 4, Not Applicable, Phase 2, Phase 3, Phase 1
perioperative nausea and vomiting
0 Actively Recruiting
Allergic Reaction
3 Actively Recruiting
Not Applicable, Phase 4
Allergic urticaria
0 Actively Recruiting
Hay Fever
1 Actively Recruiting
Phase 3
upper respiratory symptoms
0 Actively Recruiting
Pain management
0 Actively Recruiting
Anaphylaxis
3 Actively Recruiting
Phase 2, Not Applicable
Airsickness
6 Actively Recruiting
Phase 1, Not Applicable, Phase 2, Phase 3
Postoperative Pain
19 Actively Recruiting
Phase 4, Phase 1, Not Applicable, Phase 3, Early Phase 1, Phase 2
Analgesics
3 Actively Recruiting
Phase 4, Phase 1
Dermographism
0 Actively Recruiting
Nausea
0 Actively Recruiting
Nasal Congestion
1 Actively Recruiting
Not Applicable
Vasomotor Rhinitis
0 Actively Recruiting
Promethegan Reviews: What are patients saying about Promethegan?
5Patient Review
7/30/2015 This medication was extremely effective in getting rid of my nausea, and it worked very quickly. I was already in bed when I took it, as I had a bad colon infection, and it made me very sleepy. That was actually helpful, as I needed to rest at that time. I would highly recommend this medication to others.
5Patient Review
6/13/2018 This drug has been an absolute lifesaver for me during my chemo and radiation treatments. It's helped immensely with anxiety and sleeplessness. As long as you take it as prescribed, it'll work wonders for you.
5Patient Review
7/1/2020 I was prescribed this medication for my anxiety, which caused me a lot of digestive problems. This medicine worked really well for me and helped immensely. However, after 8 years my doctor suddenly said it was dangerous to take long term and took it away from me. He replaced it with Zofran, which is nowhere near as effective. I'm really sad about it.
5Patient Review
4/12/2019 This medication provided relief from my nausea very effectively.
5Patient Review
2/10/2021 This drug worked well for me in terms of nausea, sleep, and anxiety.
5Patient Review
6/24/2018 This medication is great to use in combination with other treatments.
5Patient Review
6/3/2015 This drug has been excellent for eliminating the nausea I experience during migraines. It's also prevented me from feeling nauseous when using opiates to treat my migraines, which is a huge relief.
5Patient Review
11/3/2016 Promethazine is fantastic for nausea. After my surgery, it was a life-saver. Not only does it work quickly, but the calming effect also helped me get some much-needed sleep.
5Patient Review
7/21/2017 This medication was a life-saver for me when I had a severe migraine. Not only did it help with the pain, but also with the nausea that often comes along with migraines.
5Patient Review
10/17/2015 This medication is very effective at treating nausea and vomiting. However, it is important to take it within the first half hour of experiencing these symptoms.
5Patient Review
7/21/2017 I have experienced severe migraines with nausea and vomiting. This medication helped me immensely when it was prescribed for what I thought was a virus, but was actually a migraine. I'm glad that it provided relief almost immediately. It was paired with a pain medication to ease both the pain and the nausea right away, which I appreciated.
5Patient Review
11/3/2016 After surgery for kidney stones, I was prescribed promethazine. Once it kicks in, it's great for nausea and has a calming effect that helps me sleep. This is by far the best drug for nausea that I've tried.
5Patient Review
6/13/2018 This drug has been a life saver for me! Take the prescription correctly and it’ll work very well for you
5Patient Review
6/16/2016 This medicine is really effective against nausea, and it has a calming effect too. It's been a total game changer for me and my mother.
5Patient Review
7/30/2015 This medication was given to me for extreme nausea while taking an antibiotic. It worked very quickly in getting rid of the nausea. I was already in bed as a result of a very bad colon infection and the pill did make me very sleepy. That helped me to get the rest I was needing at that time. I would highly recommend this medication.
5Patient Review
7/1/2020 I was really struggling with anxiety-induced nausea before this medication. It worked great for me for eight years, and then my doctor suddenly said it wasn't safe for long-term use. Zofran is an inferior substitute in my opinion.
5Patient Review
6/3/2015 This drug has been excellent for eliminating nausea due to migraine and preventing nausea due to opiate use when treating migraine.
5Patient Review
7/21/2017 This medication quickly and effectively alleviated my migraines, which I had originally thought were caused by a virus. Paired with another pain medication, it eased both the headache and the nausea immediately.
5Patient Review
6/13/2018 If you follow the instructions, this drug will be very effective in treating your anxiety and sleeplessness. It's been a life-saver for me during my chemotherapy and radiation treatment.
5Patient Review
11/3/2016 Promethazine is an excellent drug for nausea. It can take a little while to kick in, but once it does it's very effective and has a calming effect that helps me sleep.
5Patient Review
7/30/2015 This medication was incredibly effective at getting rid of my nausea, and fast. I was already in bed when I took it, as I had a really bad colon infection, and it made me very sleepy. That was actually helpful, as I needed to rest. I would highly recommend this medication to anyone else experiencing similar issues.
5Patient Review
2/10/2021 Perfect for nausea, sleep and anxiety.
5Patient Review
4/12/2019 I found this to be an effective treatment against nausea.
5Patient Review
10/17/2015 This medication is very effective against nausea and vomiting, as long as it's taken within the first 30 minutes of symptoms.
5Patient Review
11/3/2016 After surgery, I was prescribed promethazine for nausea. It works great to calm my stomach and help me sleep. This is a wonderful drug for anyone experiencing nausea.
5Patient Review
6/13/2018 This drug has been an absolute godsend for me. Not only does it help with the anxiety and sleeplessness brought on by chemo/radiation, but it actually makes the treatment more bearable.
5Patient Review
6/16/2016 This medicine is highly effective for nausea and has a calming effect. This pill is a miracle for me and my mother.
5Patient Review
6/24/2018 This medication is great to use in combination with other treatments.
5Patient Review
7/30/2015 This medication was very effective in quelling my nausea. I was also pleased that it made me drowsy, as I needed to sleep a lot due to a bad infection.
5Patient Review
6/3/2015 This drug has been excellent for eliminating nausea due to migraine and preventing nausea due to opiate use when treating migraine.
5Patient Review
7/1/2020 I was really struggling with anxiety and this medication helped me so much. I don't understand why my doctor took it away after eight years, saying it's suddenly dangerous for long-term use? Zofran is nowhere near as good.
5Patient Review
6/16/2016 This medicine is great for nausea and has a calming effect too. It's been a lifesaver for me and my mom.
5Patient Review
6/3/2015 This has been an effective drug for me in terms of eliminating migraine-induced nausea as well as preventing nausea when using opiates to treat migraines.
5Patient Review
10/17/2015 This medication is very effective at treating nausea and vomiting. Just be sure to take it within the first 30 minutes of feeling those symptoms.
5Patient Review
6/24/2018 This medication is great to use in combination with other treatments.
5Patient Review
2/10/2021 Perfect for nausea, sleep and anxiety.
5Patient Review
10/17/2015 This medication was very helpful in curbing my nausea and vomiting. Just make sure to take it within thirty minutes of when you start feeling those symptoms.
5Patient Review
6/16/2016 This medicine is both effective and calming, which makes it perfect for nausea. It's a real lifesaver for me and my mom.
5Patient Review
6/24/2018 This medication is great to use in combination with others.
5Patient Review
4/12/2019 This medication provided quick and effective relief from nausea.
5Patient Review
7/1/2020 This medication was really effective for my anxiety. I'm so disappointed that my doctor took it away after eight years, saying it's suddenly dangerous for long-term use. Zofran is nowhere near as good.
5Patient Review
2/10/2021 Perfect for nausea, sleep and anxiety.
5Patient Review
4/12/2019 This medication worked well for me and relieved my nausea.
5Patient Review
7/21/2017 I have experienced severe migraine headaches with nausea and vomiting. This medication helped me so much when it was prescribed for what I thought was a virus but was actually a severe migraine. I was so glad that it helped me right away. It was paired with a pain medication to ease both the pain and the nausea right away.
4.7Patient Review
8/3/2014 This has been effective in preventing nausea when used alongside the narcotic Tromadol. I tried taking Hydrocodine in the past and couldn't tolerate it because of extreme nausea. I did get constipation, but the Tromadol also causes that.
4.7Patient Review
8/27/2019 Being nauseous is one of the worst feelings and if I vomit from it just once, it's downhill from there. The headache this treatment can bring is quite bad, but I'd rather have an awful headache than be awfully nauseous and vomiting.
4.7Patient Review
8/3/2014 This medication has been very effective in preventing nausea, especially when used in conjunction with the narcotic Tromadol. I've tried taking Hydrocodine in the past but couldn't tolerate it because of how nauseous it made me.
4.7Patient Review
8/27/2019 Being nauseous is one of the worst feelings for me, and if I vomit just once it's a downhill spiral from there. This medication can make you drowsy but that's not a big set back for me. The headache it brings is quite bad, but I'd rather have an awful headache then being awfully nauseous and vomiting.
4.7Patient Review
2/17/2015 An important thing to remember is that this drug also comes in suppository form! This can be incredibly helpful because it works quickly and you don't have to worry about losing it when you vomit.
4.7Patient Review
8/3/2014 This has been very helpful in preventing nausea when taken with Tromadol. I've tried Hydrocodine in the past but couldn't tolerate it because of how badly it made me feel.
4.7Patient Review
2/17/2015 The suppository option for this drug is great because it works extremely fast and you don't have to worry about losing it when vomiting.
4.7Patient Review
8/27/2019 Nausea is one of the worst feelings, in my opinion. If I vomit just once, it's hard to stop and I feel even worse. This medication can make you drowsy, but that's not a big deal to me. The headache it brings is quite bad, but it's still better than nausea and vomiting.
4.7Patient Review
8/18/2015 This medication usually does wonders for me.
4.7Patient Review
8/3/2014 I've found this to be an effective method of preventing nausea when taking the narcotic Tromadol. In the past, I tried taking Hydrocodine but couldn't tolerate it because of how nauseous it made me. With this treatment, I did get constipation--but that's also a side effect of Tromadol.
4.7Patient Review
2/17/2015 The suppository option for this drug is great because it works quickly and you don't have to worry about losing it when vomiting.
4.7Patient Review
8/27/2019 For me, being nauseous is one of the absolute worst feelings. And if I vomit once, it's downhill from there because I can't stop. It can make you drowsy but that's not a big set back for me. The headache it brings is quite bad, but I'd rather have an awful headache then being awfully nauseous and vomiting.
4.7Patient Review
8/18/2015 This medication usually does wonders for me.
4.7Patient Review
2/17/2015 The suppository option for this drug is great because it works quickly and you don't have to worry about losing it when vomiting.
4.7Patient Review
8/18/2015 This medication usually does wonders for me.
4.7Patient Review
8/18/2015 This medication usually does wonders for me.
4.3Patient Review
12/13/2014 This medication was very effective at treating my nausea. However, it made me extremely drowsy and I slept for 14 hours straight. The next day I felt groggy and had a dull headache. I suspect that the dosage was too high for my small frame (I weigh 116 pounds). If you have sleep apnea, I would not recommend taking this medication as it could make your condition worse.
4.3Patient Review
9/11/2019 This medication has helped me a lot with my nausea. I do get tired if I take it and am sensitive to medications, so be warned. That said, it's also been great for insomnia!
4.3Patient Review
12/13/2014 This medication was effective for my nausea; however, the dosage given made me feel excessively tired and groggy the next day. I would recommend that smaller doses be given to women of a smaller stature. Additionally, if you suspect you have sleep apnea, do not take this medication as it will exacerbate the problem.
4.3Patient Review
12/13/2014 This medication was very effective in treating my nausea. However, it made me excessively tired and I felt groggy the next day. I also suspect that it exacerbated my sleep apnea symptoms. If you are considering this medication, be sure to speak with your doctor about a smaller dose if you have any concerns.
4.3Patient Review
9/11/2019 This treatment has really helped with my nausea. I do find that if I'm sensitive to medication, it can make me tired; but that's actually been a plus since it helps with my insomnia too.
4.3Patient Review
12/13/2014 I was prescribed 25 mg. for nausea and it worked wonders, though I slept for 14 hours straight. The next day I felt groggy and had a headache, so I would recommend either asking for a smaller dosage or being prepared to feel out of sorts the following day.
4.3Patient Review
9/11/2019 This medication has really helped with my nausea. However, if you're sensitive to medications, be aware that you may feel tired after taking this medicine. It also helps with my insomnia, which is a plus.
4.3Patient Review
9/11/2019 This medication has helped a lot with my nausea. I do get tired if I take it and am sensitive to medications, but that also helps me fall asleep so it's not all bad.
4Patient Review
8/8/2021 This medication can make me drowsy, however it effectively prevents vomiting and helps me keep food down.
4Patient Review
5/23/2014 I have been hospitalized over a dozen times for vomiting and diarrhea, but this medication always does the trick.
4Patient Review
5/23/2014 I've been hospitalized over a dozen times for vomiting and diarrhea, but this medication really does the trick for me.
4Patient Review
8/8/2021 Although it makes me drowsy, this treatment is effective for reducing vomiting and helping me keep food down.
4Patient Review
5/23/2014 I have been hospitalized more than a dozen times due to vomiting and diarrhea. This medication really helps me out.
4Patient Review
8/8/2021 This medication makes me drowsy, but it has been effective in curbing my vomiting and helping me keep food down.
4Patient Review
5/23/2014 I have been hospitalized over a dozen times for vomiting and diarrhea, but this medication really does the trick for me.
4Patient Review
8/8/2021 Though it leaves me feeling pretty drowsy, this medication helps with my vomiting and lets me keep food down.
1Patient Review
8/26/2015 I would use extreme caution before taking this drug, especially if you are also taking other medication. I ended up in the ER with a number of serious side effects that could have been life-threatening. This is not a drug to be used long-term.
1Patient Review
8/26/2015 I would use extreme caution before mixing this drug with any others. I had to go to the ER as a result of serious side effects that could have been deadly. Do not use this for long term treatment.
1Patient Review
8/26/2015 I would use extreme caution before taking this drug, especially if you are already on other medication. I landed in the ER with numerous life-threatening side effects. This is not a drug to be taken lightly or for long periods of time.
1Patient Review
8/26/2015 I would use extreme caution before taking this drug, as it landed me in the ER with a number of serious side effects. Do not use this medication long-term.
Patient Q&A Section about promethegan
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is Promethegan the same as promethazine?
"Promethazine should not be used in children younger than 2 years because it may causeslowed or shallow breathing, which could be fatal."
Answered by AI
What is Promethegan used for?
"Promethazine is an anti-nausea medication that is also used to treat allergy symptoms. It works by preventing the release of a chemical called histamine in the body."
Answered by AI
How long after promethazine suppository Can I poop?
"For best results from this medicine, use it at around the same time every day.
After using this medication, stay lying down for a few minutes and don't have a bowel movement for at least an hour so the drug can be absorbed. The suppository is only for rectal use. To get the best results from this medicine, use it at around the same time every day."
Answered by AI
What is promethazine 25mg suppositories used for?
"This medication prevents and treats the symptoms of an allergic reaction by blocking histamine, a substance that is released by the body during an allergic reaction. In addition, this medication may help you relax, go to sleep, and relieve nausea, vomiting, or pain before or after procedures."
Answered by AI