Proair Hfa

Hyperkalemia, Acute Bronchitis, Pneumonia + 18 more

Treatment

9 FDA approvals

20 Active Studies for Proair Hfa

Treatment for

Hyperkalemia

What is Proair Hfa

Salbutamol

The Generic name of this drug

Treatment Summary

Salbutamol is a medication used to treat asthma and COPD. It is a selective beta2-adrenergic receptor agonist that is 29 times more effective at targeting the lungs compared to the heart. Salbutamol is a mixture of two different isomers, the R- and S-isomers. The R-isomer is 150 times more effective than the S-isomer, but it is also more expensive. Salbutamol is used to treat acute episodes of bronchospasm, prevent exercise-induced asthma, and treat chronic respiratory disorders like COPD.

Proair HFA

is the brand name

image of different drug pills on a surface

Proair Hfa Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Proair HFA

Salbutamol

1981

314

Approved as Treatment by the FDA

Salbutamol, also known as Proair HFA, is approved by the FDA for 9 uses like prophylaxis of Exercise-induced bronchospasm and prophylaxis of Bronchospasm .

prophylaxis of Exercise-induced bronchospasm

prophylaxis of Bronchospasm

Bronchospasm, Exercise-Induced

Bronchial Spasm

Asthma, Exercise-Induced

Chronic Obstructive Pulmonary Disease

Used to treat Chronic Obstructive Pulmonary Disease (COPD) in combination with Ipratropium

Bronchodilator Agents

Used to treat need of more than one bronchodilator in combination with Ipratropium

Exercise-Induced Bronchospasm

Bronchospasm

Effectiveness

How Proair Hfa Affects Patients

Salbutamol, also known as albuterol, is a drug used to open up the airways and make it easier to breathe. It works by stimulating the beta-1 and beta-2 receptors in the body, causing vasodilation, muscle relaxation, and a faster heartbeat. Although Salbutamol is mostly specific to the beta-2 receptors, it can still affect beta-1 receptors which can cause an increase in insulin and sugar levels in the blood. Salbutamol may also cause a decrease in potassium levels.

How Proair Hfa works in the body

Salbutamol works by activating beta2-adrenergic receptors on airway smooth muscle. This activates a chemical process that relaxes the muscle and lowers the amount of calcium in the cells. This reduces the tension in the muscles, allowing the airways to open up. Salbutamol also prevents the release of mediators from mast cells in the airway. It's usually effective within 5 to 15 minutes and can last up to 6 hours. It has fewer cardiovascular side effects than isoproterenol and produces more respiratory relief.

When to interrupt dosage

The suggested measure of Proair Hfa is contingent upon the diagnosed condition, including Bronchodilator Agents, Emphysema and Wheezing. The quantity of dosage fluctuates in agreement with the technique of delivery featured in the table underneath.

Condition

Dosage

Administration

Hyperkalemia

2.0 mg/mL, , 2.5 mg/mL, 0.09 mg, 3.0 mg/mL, 2.0 mg, 4.0 mg, 8.0 mg, 0.75 mg/mL, 1.5 mg/mL, 25.0 mg/mL, 0.63 mg/mL, 1.25 mg/mL, 0.108 mg, 5.0 mg/mL, 2.4 mg, 0.045 mg, 3.0 mg, 0.4 mg, 0.2 mg, 0.1 mg, 0.05 %, 0.1 %, 0.2 %, 0.83 mg/mL, 0.12 mg, 4.8 mg, 0.00009 mg/mg, 1.0 mg/mL, 0.1 mg/dose, 0.5 mg/mL, 0.2 mg/pump actuation, 0.097 mg/pump actuation, 0.1 mg/pump actuation, 0.4 mg/mL, 0.25 mg/mL, 0.12 mg/pump actuation

, Oral, Syrup, Syrup - Oral, Respiratory (inhalation), Solution, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Tablet, Tablet - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Solution - Respiratory (inhalation), Intrabronchial, Solution - Intrabronchial, Aerosol, metered - Oral, Occlusive dressing technique, Syrup - Occlusive dressing technique, Tablet, extended release, Tablet, extended release - Oral, Intravenous, Powder, Powder - Respiratory (inhalation), Liquid, Intramuscular, Liquid - Intramuscular, Capsule - Respiratory (inhalation), Capsule, Liquid - Oral, Liquid - Respiratory (inhalation), Spray, metered - Respiratory (inhalation), Powder, metered, Powder, metered - Respiratory (inhalation), Inhalant, Spray, metered, Aerosol, spray - Oral, Aerosol, spray, Spray, Spray - Oral, Aerosol, metered - Intrabronchial, Nasal, Inhalant - Respiratory (inhalation), Solution - Nasal, Solution - Intramuscular, Solution - Oral, Solution - Intravenous, Liquid - Intravenous, Inhalant - Nasal, Inhalant - Oral

Pneumonia

Bronchial Spasm

prophylaxis of Bronchospasm

Respiratory Tract Infections

Acute Bronchitis

Influenza

Bronchitis, Chronic

Asthma

Bronchodilation

Bronchitis

Airway secretion clearance therapy

excess mucus or phlegm

Emphysema

Asthma

Asthma, Exercise-Induced

Asthma

Bronchodilator Agents

Bronchospasm, Exercise-Induced

Chronic Obstructive Pulmonary Disease

Warnings

There are 20 known major drug interactions with Proair Hfa.

Common Proair Hfa Drug Interactions

Drug Name

Risk Level

Description

Hydroxyzine

Major

The risk or severity of QTc prolongation can be increased when Salbutamol is combined with Hydroxyzine.

Mobocertinib

Major

The risk or severity of QTc prolongation can be increased when Salbutamol is combined with Mobocertinib.

Ziprasidone

Major

The risk or severity of QTc prolongation can be increased when Salbutamol is combined with Ziprasidone.

1-benzylimidazole

Minor

The risk or severity of hypertension can be increased when Salbutamol is combined with 1-benzylimidazole.

2,5-Dimethoxy-4-ethylamphetamine

Minor

The risk or severity of hypertension can be increased when Salbutamol is combined with 2,5-Dimethoxy-4-ethylamphetamine.

Proair Hfa Toxicity & Overdose Risk

Signs of an overdose on Albuterol include high heart rate, high or low blood pressure, seizures, headache, trembling, muscle cramps, dry mouth, palpitations, nausea, dizziness, tiredness, difficulty sleeping, high blood sugar, low potassium, and acidosis. Pregnant women should use caution when taking Albuterol as there is a risk of birth defects. Nursing mothers should also use caution and talk to their doctor as Albuterol can be passed through breast milk. Albuterol has not been tested in children under 4 years of age. Elderly patients should start with a lower

image of a doctor in a lab doing drug, clinical research

Proair Hfa Novel Uses: Which Conditions Have a Clinical Trial Featuring Proair Hfa?

383 active trials are currently being conducted to ascertain the potential of Proair Hfa to alleviate Respiratory Tract Infections, Asthma and Chronic Obstructive Pulmonary Disease (COPD).

Condition

Clinical Trials

Trial Phases

Chronic Obstructive Pulmonary Disease

71 Actively Recruiting

Phase 3, Phase 1, Phase 2, Not Applicable, Early Phase 1, Phase 4

Bronchospasm, Exercise-Induced

0 Actively Recruiting

Asthma

89 Actively Recruiting

Phase 1, Phase 4, Early Phase 1, Not Applicable, Phase 2, Phase 3

prophylaxis of Bronchospasm

0 Actively Recruiting

Influenza

27 Actively Recruiting

Not Applicable, Phase 4, Phase 2, Phase 1, Phase 3

Hyperkalemia

3 Actively Recruiting

Phase 3, Phase 2, Phase 1

Bronchitis, Chronic

0 Actively Recruiting

excess mucus or phlegm

0 Actively Recruiting

Bronchodilator Agents

0 Actively Recruiting

Pneumonia

15 Actively Recruiting

Not Applicable, Early Phase 1, Phase 2

Bronchial Spasm

0 Actively Recruiting

Asthma

1 Actively Recruiting

Phase 2

Airway secretion clearance therapy

0 Actively Recruiting

Respiratory Sounds

4 Actively Recruiting

Phase 2, Phase 3

Asthma

1 Actively Recruiting

Phase 4

Asthma, Exercise-Induced

0 Actively Recruiting

Emphysema

4 Actively Recruiting

Phase 2, Not Applicable

Bronchitis

0 Actively Recruiting

Acute Bronchitis

8 Actively Recruiting

Phase 4, Not Applicable, Phase 3, Early Phase 1

Bronchodilation

0 Actively Recruiting

Proair Hfa Reviews: What are patients saying about Proair Hfa?

Patient Review

7/27/2022

Proair Hfa for Asthma

I have seen people complain about only getting 40 good puffs out of this before it clogs. My friend suggested that I rinse the applicator under running hot water, let it air dry overnight, and shake it at least 20 times before using. This has worked really well for me and I haven't had any issues since.

Patient Review

4/17/2017

Proair Hfa for Asthma

Works really quickly for me, which is a lifesaver given my asthma.

4.3

Patient Review

12/1/2017

Proair Hfa for Chronic Obstructive Lung Disease

I've been using this since March 2017 to help manage my breathing. So far, it's been effective in helping me avoid triggering an attack.

Patient Review

12/16/2017

Proair Hfa for Asthma

This inhaler didn't work very well for my severe asthma and it's extremely expensive.

1.7

Patient Review

6/10/2019

Proair Hfa for Asthma

This inhaler is effective when it works, but only for about 60 puffs. After that, the spray nozzle gets clogged and it's effectively useless. As someone with asthma, this is not a very comforting feeling.

Patient Review

8/31/2017

Proair Hfa for Asthma

In my 40 years of experience with asthma, I have found PROAIR to be the worst inhaler on the market. VENTOLIN is much more effective in my opinion. It seems like the decision to stop production of the other inhalers was made by people who don't suffer from asthma and don't understand how important a good inhaler can be.

Patient Review

1/25/2017

Proair Hfa for Bronchitis

I sought out medical attention for my cough at an urgent care, and they prescribed me this inhaler. Unfortunately, it did nothing to improve my condition over the course of four or five days. If you're considering this medication, I would recommend looking elsewhere – Symbicort worked much better for me.

Patient Review

4/29/2018

Proair Hfa for Chronic Obstructive Lung Disease

My husband needed to start using an inhaler and Ventolin worked great for him, but then his doctor prescribed Proventil and our insurance gave us ProAir. The pump was faulty from the beginning; I never experienced this issue when I had asthma years ago. It's a waste of money and it's dangerous--this should be taken off the market.

Patient Review

11/29/2017

Proair Hfa for Asthma Attack

Do not bother with this inhaler. It actually makes your breathing worse by using a powder instead of liquid. I've had to go to the ER twice now because Walgreens won't give me Proventil, which is what my doctor prescribed in the first place.

Patient Review

1/9/2019

Proair Hfa for Asthma

The propulsion system is way too weak on this product. I often can't tell if I'm actually receiving the medication or not. It's very scary not knowing whether or not the invisible mist is working, but my insurance won't pay for anything else. If you can, try to get a different prescription from your doctor.

Patient Review

5/18/2021

Proair Hfa for Asthma

The new design for this inhaler is really not good. You just have to huff it, and there's no indicator if you're actually getting any medicine. I'm worried that if I have a real asthma attack, I won't be able to get the right dosage because of how hard you have to puff. Avoid this new model altogether and stick with the old one.

Patient Review

2/12/2017

Proair Hfa for Asthma Attack

This medication didn't do much for me, and actually made my symptoms worse.

Patient Review

8/4/2020

Proair Hfa for Asthma Attack

I have both asthma and RA, which makes using my hands difficult. Proair is very hard for me to use; I can't open the lid or compress the canister, so it doesn't help me during an asthma attack. It's also more expensive than other inhalers that actually work.

Patient Review

9/5/2018

Proair Hfa for Asthma

This product has not worked for me at all, and the delivery system has failed on three separate occasions. I've had to get replacements from my pharmacy, but it's been an expensive process.

Patient Review

2/9/2017

Proair Hfa for Chronic Obstructive Lung Disease

I think this drug is dangerous and not at all effective. My pharmacist told me that the doctors who prescribe proair receive a "thank you" payment of $25 from the pharmaceutical company. I find this unethical and will be asking my doctor to switch my prescription next week.

Patient Review

9/7/2022

Proair Hfa for Asthma Attack

I was very disappointed with this product. It spits instead of making a mist, and I saw no relief from my asthma symptoms.

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about proair hfa

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many times a day can I use my ProAir inhaler?

"The bronchodilator inhalers should be used 4-6 times a day since the medication works for 4-6 hours after inhaling it."

Answered by AI

Is ProAir inhaler a steroid?

"Proair is a medication used to treat and prevent wheezing and shortness of breath caused by asthma. Proair is a bronchodilator, and Symbicort is a combination of a steroid and a long-acting bronchodilator."

Answered by AI

Is ProAir HFA the same as albuterol?

"The generic version of ProAir HFA is called albuterol sulfate. It is an exact copy of the active drug in ProAir HFA and is just as safe and effective."

Answered by AI

What is ProAir HFA inhaler used for?

"Albuterol belongs to a class of drugs known as bronchodilators.

Albuterol sulfate is a generic drug that is used to prevent and treat wheezing and shortness of breath caused by breathing problems such as asthma and chronic obstructive pulmonary disease. Albuterol is also used to prevent asthma that is brought on by exercise. bronchodilators."

Answered by AI

Clinical Trials for Proair Hfa

Have you considered Proair Hfa clinical trials?

We made a collection of clinical trials featuring Proair Hfa, we think they might fit your search criteria.

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MoblO2 for Chronic Lung Diseases

18+

All Sexes

Stanford, CA

Many patients with chronic lung disease (e.g., chronic obstructive pulmonary disease (COPD) or interstitial lung disease (ILD)) require supplemental oxygen (O2) at some point during their disease course. Practitioners prescribe O2 to patients with chronic lung disease in hopes of the following: 1) that it will limit desaturation events and combat breathlessness, thus preventing the frustratingly slow pace and numerous rest breaks patients are forced to adopt while doing even simple tasks; 2) that it will allow patients to be more active physically (perhaps increase their ability to exercise) and socially (perhaps leave the home more often); 3) that it will stave off putative complications of hypoxemia (e.g., cognitive dysfunction, pulmonary hypertension) and 4) that it will improve health-related quality of life (HRQL). However, despite the rationale for O2, and prescribers' good intentions, patients generally view O2 with frustration and fear - it threatens their HRQL, which is already impaired by having a condition that imposes itself on every aspect of their lives. Nasal cannulas and delivery devices call unwanted attention to patients when they are out in public. O2 users feel stigmatized and are often viewed as "smokers who get what they deserve, even if they never smoked a day in their lives" - or as disabled, sick or even infectious. O2 steals patients' independence, forcing them to plan their lives around it. The anxiety that patients and their caregivers experience around running out of oxygen, or not getting enough, immobilizes them and restricts participation in activities outside of the home. O2 disrupts the home environment, adding stress, and creating a burden for patients' caregiver-loved-ones who are often saddled with the responsibility of ensuring adequate equipment and supply of O2, and O2 is a constant reminder to patients they are living with a condition that could shorten their lives. O2 delivery equipment is typically heavy, unwieldy and intimidating. Different recommendations (e.g., insurance companies use 88% as a cut-off for SpO2, while many practitioners focus on 90%) make it confusing for patients, which almost certainly affects adherence. O2-requiringpatients are starving for things that can make their lives easier. An auto-adjusting O2 delivery device - one that automatically delivers the correct amount of O2 to maintain blood oxygen at desired, pre-set levels - would alleviate the need for patients to constantly (incessantly for many) monitor their peripheral oxygen saturation (SpO2) and adjust O2flow to meet the demands as exertion levels vary . The MoblO2 device is a battery-operated, light-weight, closed-loop O2 delivery device that houses a regulator (which attaches to compressed gas O2 tanks) and adjusts O2 flow to meet a pre-set blood oxygen level. A pulse oximeter is worn on the ear and transmits via Bluetooth to the device, which adjusts an internal valve to control flow on a second-to-second basis. The user sets the dial to the highest flow of O2 needed to meet the demands of activities they might perform (up to 15 liters per minute), and the device adjusts flow, up to the pre-set level to maintain SpO2 at a preset level (e.g., \> 90%). To conserve O2 supply in the tank - and to avoid over-oxygenation (which could be problematic for a small percentage of patients with the most severe COPD) - the MoblO2 begins to limit O2 flow at a SpO2 of 93%. The device can be manually over-ridden by the user, and should the battery run out - or the device fail for some unforeseen reason - the default position is valve open, so the users receive whatever flow of oxygen has been set on the dial. Given the substantial burdens of O2 on patients and their families, the hassles patients describe with having to monitor their SpO2 and repeatedly adjust the flow of O2 to meet their needs, patients and experts around the world have called for improvements in O2 delivery equipment. The MoblO2 is just such a remarkable improvement and a giant step forward in helping to ease the burdens of O2 on patients who require it. The purpose of this study is to investigate the effects of the MoblO2 O2 delivery device on a range of outcomes, including physical activity, amount (liters) O2 use; maintenance of adequate SpO2 levels; patient reported outcomes including symptoms, HRQL and satisfaction with the MoblO2 O2 device.

Waitlist Available

Has No Placebo

Stanford University

Jeff Swigris, DO, MS

Minnesota Health Solutions