Prilocaine Hydrochloride

Local Anaesthesia therapy

Treatment

1 FDA approval

0 Active Studies for Prilocaine Hydrochloride

What is Prilocaine Hydrochloride

Prilocaine

The Generic name of this drug

Treatment Summary

Articaine is a local anesthetic used to numb the area of a dental procedure. It works similarly to lidocaine and is commonly used in dentistry for infiltration anesthesia.

Citanest Forte

is the brand name

image of different drug pills on a surface

Prilocaine Hydrochloride Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Citanest Forte

Prilocaine

1965

73

Approved as Treatment by the FDA

Prilocaine, also known as Citanest Forte, is approved by the FDA for 1 uses such as Local Anaesthesia therapy .

Local Anaesthesia therapy

Effectiveness

How Prilocaine Hydrochloride Affects Patients

Prilocaine works by attaching to the inside of sodium channels, which stops electrical signals from travelling through the nerve cells. This block is temporary and when the drug moves away from the cell, the nerve signals can travel again.

How Prilocaine Hydrochloride works in the body

Prilocaine works by blocking sodium channels on the surface of nerve cells, reducing the spread of seizure activity and suppressing arrhythmia.

When to interrupt dosage

The prescribed dose of Prilocaine Hydrochloride is dependent upon the established condition. The quantity of dosage is contingent upon the technique of application as specified in the table below.

Condition

Dosage

Administration

Local Anaesthesia therapy

, 40.0 mg/mL, 0.025 mg/mg, 2.5 %, 50.0 mg/mL, 2.5 mg/mg, 0.05 mg/mg

, Injection, solution, Subcutaneous, Injection, solution - Subcutaneous, Cream, Cream - Topical, Topical, Periodontal, Dental, Injection, solution - Dental, Gel, Gel - Periodontal, Kit, Kit - Topical, Infiltration, Gel - Topical, Solution, Solution - Infiltration, Spray, Spray - Cutaneous, Cutaneous, Patch, Patch - Topical, Submucosal, Injection, solution - Submucosal, Parenteral, Injection, solution - Parenteral, Intra-articular; Intramuscular; Topical, Cream; Kit - Topical, Kit - Cutaneous; Topical, Oral; Topical, Ointment, Ointment - Topical, Cream; Kit, Cutaneous; Topical

Warnings

Prilocaine Hydrochloride Contraindications

Condition

Risk Level

Notes

Methemoglobinemia

Do Not Combine

Congenital methaemoglobinaemia

Do Not Combine

Pulse Frequency

Do Not Combine

There are 20 known major drug interactions with Prilocaine Hydrochloride.

Common Prilocaine Hydrochloride Drug Interactions

Drug Name

Risk Level

Description

Azelastine

Major

Prilocaine may increase the central nervous system depressant (CNS depressant) activities of Azelastine.

Ethanol

Major

Prilocaine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.

Oliceridine

Major

The risk or severity of hypotension, sedation, death, somnolence, and respiratory depression can be increased when Prilocaine is combined with Oliceridine.

Technetium Tc-99m tilmanocept

Major

Prilocaine may decrease effectiveness of Technetium Tc-99m tilmanocept as a diagnostic agent.

Thalidomide

Major

Prilocaine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.

image of a doctor in a lab doing drug, clinical research

Prilocaine Hydrochloride Novel Uses: Which Conditions Have a Clinical Trial Featuring Prilocaine Hydrochloride?

Condition

Clinical Trials

Trial Phases

Local Anaesthesia therapy

0 Actively Recruiting

Patient Q&A Section about prilocaine hydrochloride

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is prilocaine injection used for?

"Prilocaine injection is used to numb the mouth before a dental procedure. Your dentist will give you this medicine. This product is available in the following dosage forms: Solution."

Answered by AI

Is prilocaine still used?

"Lidocaine and prilocaine topical cream is used to numb the skin or genital area before certain medical procedures. It is also used to prevent pain from an injection, drawing blood from a vein, or minor surgeries like removing warts."

Answered by AI

What type of anesthetic is prilocaine?

"Prilocaine is a local anesthetic that is similar to lidocaine. Prilocaine was created in 1965 and it does not last as long as other local anesthetics. This makes it a good option for people who are having surgery that does not require a long recovery time."

Answered by AI

Is prilocaine the same as lidocaine?

"This medication contains a local anesthetic that works by temporarily numbing the skin and surrounding area."

Answered by AI