Potassium Chloride

Hypokalemia, Terminal state, Hypokalemia + 26 more

Treatment

2 FDA approvals

20 Active Studies for Potassium Chloride

Treatment for

Hypokalemia

What is Potassium Chloride

Potassium chloride

The Generic name of this drug

Treatment Summary

Potassium chloride is a white powder used to replace lost electrolytes, help treat low levels of potassium, provide a neutral pH balance, and as an ingredient in fertilizers and explosives.

Thermotabs Buffered Salt Supplement

is the brand name

image of different drug pills on a surface

Potassium Chloride Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Thermotabs Buffered Salt Supplement

Potassium chloride

1937

841

Approved as Treatment by the FDA

Potassium chloride, otherwise called Thermotabs Buffered Salt Supplement, is approved by the FDA for 2 uses such as Hypokalemia and Hypokalemia .

Hypokalemia

Effectiveness

How Potassium Chloride Affects Patients

Potassium is an important part of the body's cells. It helps with nerve transmission, muscle contraction, and kidney function. Most people take in 50-100 milliequivalents (mEq) of potassium with their diet every day. Potassium can be lost through illnesses like diarrhea, and with certain medicines like diuretics. When this happens, it can lead to symptoms like weakness, fatigue, and irregular heartbeats. To fix this, people can add high potassium foods to their diets or take potassium supplements. Depending on the cause of the potassium deficiency, people may need to take a potassium salt like potassium bic

How Potassium Chloride works in the body

Eating potassium-rich foods or taking potassium supplements can help restore normal potassium levels.

When to interrupt dosage

The recommended dosage of Potassium Chloride is contingent upon the diagnosed circumstance, such as Electrolyte replacement, Plasma Volume Replacement and Rehydration. The amount of dosage is dependent on the mode of administration set out in the table below.

Condition

Dosage

Administration

Sudden Cardiac Arrest

0.75 mg/mL, , 150.0 mg/mL, 300.0 mg/mL, 1500.0 mg, 1875.0 mg, 750.0 mg, 600.0 mg, 1125.0 mg, 149.0 mg/mL, 0.3 mg/mL, 0.37 mg/mL, 3.0 mg/mL, 1.5 mg/mL, 2.97 mg/mL, 100.0 mg/mL, 0.1 meq/mL, 0.2 meq/mL, 0.3 meq/mL, 0.4 meq/mL, 1.49 mg/mL, 2.0 meq/mL, 4.0 meq/mL, 1.5 mg/mg, 1250.0 mg, 10.0 meq, 8.0 meq, 20.0 meq, 1.48 mg/mL, 0.0297 mg/mg, 0.0148 mg/mg, 0.0298 mg/mg, 0.754 mg/mL, 0.74 mg/mL, 25.0 meq, 99.0 mg, 10.0 %, 6200.0 mg, 500.0 mg, 7650.0 mg, 15260.0 mg, 13000.0 mg, 12500.0 mg, 25000.0 mg, 900.0 mg, 0.075 %, 760.0 mg, 2970.0 mg, 3050.0 mg, 190.0 mg, 740.0 mg, 0.12 %, 2.98 mg/mL, 2.82 mg/mL, 0.4 mg/mL, 14.9 mg/mL, 22.4 mg/mL, 7.46 mg/mL, 29.8 mg/mL, 1.193 mg/mL, 2.2 mg/mL, 157.0 mg, 149.1 mg/mL, 1.0 mg/mL, 50.0 mg, 21.0 mg, 0.02 meq/mg, 1.3 mg/mL, 1.41 mg/mL, 2.24 mg/mL, 3280.0 mg/mL, 0.745 mg/mL, 1.79 mg/mL, 0.0001 mg/mg, 20.0 mg, 0.0002 mg/mg, 34.0 mg, 7.5 mg, 1.015 mg/mL, 0.224 mg/mL, 1.875 mg/mg, 0.314 mg/mL, 0.157 mg/mL, 0.395 mg/mL, 4.87 mg/mL, 0.97 mg/mL, 0.746 mg/mL, 1000.0 mg, 2.05 mg/mL, 1.3 meq/mL, 75.0 mg/mL, 2.6 meq/mL, 1.11 mg/mL, 1.74 mg/mL, 1.19 mg/mL, 4.92 mg/mL, 125.0 mg/mL, 1015.0 mg, 0.004 meq/mL, 0.002 meq/mL, 3.28 mg/mL, 0.7 %, 0.038 %, 72.0 mg, 30.0 mg, 5.0 mg, 27.2 mg, 2.3 mg/mL, 2200.0 mg, 1200.0 mg, 1.4 mg/mL, 2250.0 mg, 24.5 mg, 7.45 mg/mL, 0.01 mg/mg, 0.375 mg/mL, 0.45 mg/mL, 250.0 mg/mL, 246.0 mg/mL, 3.355 mg/mL, 6.7 mg/mL, 10.1 mg/mL, 10.0 mg/mL, 5.02 mg/mL, 2.746 mg/mL, 3.35 mg/mL, 5.032 mg/mL, 6.71 mg/mL, 4.12 mg/mL, 8.39 mg/mL, 5.49 mg/mL, 0.398 mg/mL, 8.24 mg/mL, 2.75 mg/mL, 2.384 mg/mL, 3.36 mg/mL, 251.6 mg/mL, 1.784 mg/mL, 5.491 mg/mL, 0.38 mg/mL, 0.23468 mg/mg, 2.609 mg/mL, 10.06 mg/mL, 0.199 mg/mL, 200.0 mg/mL, 13.47 mg/mL, 10.05 mg/mL, 2.68 mg/mL, 1.86 mg/mg, 0.298 mg/mL, 7.828 mg/mL, 5.4914 mg/mL, 0.149 mg/mL, 5.03 mg/mL, 8.237 mg/mL, 8.387 mg/mL, 44.7 mg/mL, 4.119 mg/mL, 13.42 mg/mL, 2.63 mg/mL, 2.61 mg/mL, 0.15 mg/mL, 10.064 mg/mL, 0.075 mg/mL, 3.914 mg/mL, 1.2 mg/mL, 6.6 mg/mL, 11.74 mg/mL, 5.22 mg/mL, 74.55 mg/mL, 8.2 mg/mL, 0.01065 mg/mg, 5.5 mg/mL, 0.6245 mg/mL, 5.219 mg/mL, 0.76 mg/mL, 10.98 mg/mL, 3.4 mg/mL, 7.8278 mg/mL, 2.6093 mg/mL, 37.3 mg/mL, 8.38 mg/mL, 0.0304 mg/mg, 185.8 mg/mL, 74.6 mg/mL, 0.01 mmol/mL, 5.2185 mg/mL, 0.001 meq/mL, 1.57 mg/mL, 3.14 mg/mL, 2.74 mg/mL, 59.6 mg/mL, 5.2 mg/mL, 0.03 mg/mg, 2.39 mg/mL, 1.0 meq/mL, 37.5 mg, 13.0 mg, 5.5 mg, 71.5 mg, 0.055 mg/mg, 0.065 mg/mg, 55.0 mg, 105.0 mg, 15.0 mg, 57.2 mg, 0.5 mg, 35.0 mg, 12.5 mg, 25.0 mg, 200.0 mg, 75.0 mg, 0.02 mmol/mL, 80.0 mg

Solution - Ophthalmic, Ophthalmic, , Solution, Solution - Oral, Oral, Powder, for solution - Oral, Tablet, extended release, Tablet, film coated, extended release, Tablet, extended release - Oral, Capsule, extended release - Oral, Capsule, extended release, Powder, for solution, Tablet, film coated, extended release - Oral, Parenteral, Injection, solution, concentrate, Irrigant, Irrigation, Irrigant - Irrigation, Injection, solution, concentrate - Parenteral, Solution - Irrigation, Injection, solution - Intravenous, Intravenous, Solution - Intravenous, Injection, solution, Injection, Injection - Intravenous, Liquid, Liquid - Oral, Injection, solution, concentrate - Intravenous, Tablet, effervescent, Capsule - Oral, Tablet, effervescent - Oral, Capsule, Powder, for solution - Nasogastric; Oral, Nasogastric; Oral, Tablet, Tablet - Oral, Powder, Powder - Oral, Capsule, coated, extended release, Capsule, coated, extended release - Oral, Liquid - Hemodialysis, Hemodialysis, Liquid - Intravenous, Liquid - Irrigation, Powder - Hemodialysis, Solution - Intraocular, Intra-arterial, Intraocular, Solution - Intra-arterial, Kit; Powder, for solution; Tablet, delayed release - Oral, Solution - Intrathecal, Intrathecal, Solution - Hemodialysis, Kit; Powder, for solution; Tablet, delayed release, Granule, effervescent, Granule, effervescent - Oral, Liquid - Intraocular, Aerosol, Aerosol - Oral, Nasogastric, Powder, for solution - Nasogastric, Spray, Liquid - Buccal, Spray - Buccal, Buccal, Hemodialysis; Intravenous, Solution - Hemodialysis; Intravenous, Injection, solution - Intra-arterial, Emulsion - Topical, Kit - Oral, Kit, Patch, Topical, Patch - Topical, Emulsion, Solution - Extracorporeal, Injection - Intrathecal, Extracorporeal, Solution, for slush - Irrigation, Solution, for slush, Injection, emulsion - Intravenous, Injection, emulsion, For solution - Oral, For solution, Kit; Solution - Intraocular, Douche - Vaginal, Kit; Solution, Douche, Kit; Solution - Intraocular; Irrigation, Vaginal, Emulsion - Intravenous, Intraocular; Irrigation, Powder, for solution - Intraocular, Liquid - Ophthalmic, Injection, solution - Irrigation, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Oral; Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical

Acid- Base Balance

Rehydration

Anorexia

fluid and electrolyte maintenance therapy

Hypotonic Dehydration

Bowel preparation therapy

Parenteral Nutrition

Plasma Volume Replacement

hypodermoclysis

Hypokalemia

eye surgery

Hypokalemia

Hypovolemia

Urine alkalinization therapy

Fluid replacement therapy

Colonoscopy

Xerostomia

Isotonic Dehydration

Edema

Warnings

Potassium Chloride Contraindications

Condition

Risk Level

Notes

inhibited gastrointestinal capsule passage

Do Not Combine

Disease

Do Not Combine

Hyperkalemia

Do Not Combine

There are 20 known major drug interactions with Potassium Chloride.

Common Potassium Chloride Drug Interactions

Drug Name

Risk Level

Description

Amiloride

Major

The risk or severity of hyperkalemia can be increased when Potassium chloride is combined with Amiloride.

Canrenoic acid

Major

The risk or severity of hyperkalemia can be increased when Potassium chloride is combined with Canrenoic acid.

Canrenone

Major

The risk or severity of hyperkalemia can be increased when Potassium chloride is combined with Canrenone.

Eplerenone

Major

The risk or severity of hyperkalemia can be increased when Potassium chloride is combined with Eplerenone.

Spironolactone

Major

The risk or severity of hyperkalemia can be increased when Potassium chloride is combined with Spironolactone.

Potassium Chloride Toxicity & Overdose Risk

Taking potassium orally usually does not cause serious harm, but if too much is taken or if the body has difficulty eliminating it, a person may develop dangerously high levels of potassium. Hyperkalemia is often symptomless and can only be identified by a blood test that shows a potassium level of 6.5-8.0 mEq/L. If the potassium level becomes too high, people may experience changes to their heart rhythm, muscle paralysis, and cardiovascular collapse.

image of a doctor in a lab doing drug, clinical research

Potassium Chloride Novel Uses: Which Conditions Have a Clinical Trial Featuring Potassium Chloride?

21 active clinical trials are investigating the potential of Potassium Chloride for Rehydration, Colonoscopy and Edema alleviation.

Condition

Clinical Trials

Trial Phases

Hypovolemia

0 Actively Recruiting

Bowel preparation therapy

1 Actively Recruiting

Phase 1, Phase 2

Electrolyte replacement

0 Actively Recruiting

Haemofiltration

0 Actively Recruiting

Hypokalemia

0 Actively Recruiting

Hypotonic Dehydration

0 Actively Recruiting

Hemodialysis

13 Actively Recruiting

Not Applicable, Phase 2

Terminal state

0 Actively Recruiting

Acid- Base Balance

0 Actively Recruiting

Fluid replacement therapy

0 Actively Recruiting

Hypokalemia

0 Actively Recruiting

Urine alkalinization therapy

0 Actively Recruiting

Rehydration

0 Actively Recruiting

Xerostomia

0 Actively Recruiting

Parenteral Nutrition

0 Actively Recruiting

Sudden Cardiac Arrest

5 Actively Recruiting

Not Applicable

Plasma Volume Replacement

0 Actively Recruiting

eye surgery

0 Actively Recruiting

Colonoscopy

3 Actively Recruiting

Not Applicable

Open Heart Surgery

1 Actively Recruiting

Phase 1, Phase 2

Potassium Chloride Reviews: What are patients saying about Potassium Chloride?

4.7

Patient Review

11/4/2014

Potassium Chloride for Low Amount of Potassium in the Blood

Treatment solved my leg and hand cramps, but I experienced some nasty side effects like heart racing, anxiety, and stomach sickness.

Patient Review

2/26/2017

Potassium Chloride for Low Amount of Potassium in the Blood

After using Bumex, my hands started cramping up. I did some research and discovered that this was due to a potassium deficiency. Once I took a potassium pill, the problem was solved! (Of course, always check with your doctor first.)

Patient Review

1/2/2019

Potassium Chloride for Low Amount of Potassium in the Blood

I'm not entirely sure why I need to be taking this medication, as I haven't noticed any real benefits.

Patient Review

3/22/2012

Potassium Chloride for Low Amount of Potassium in the Blood

3.7

Patient Review

2/22/2013

Potassium Chloride for Low Amount of Potassium in the Blood

Unfortunately, this medication caused me a lot of gastrointestinal discomfort. Bloating, gas, and irritation were all constant problems.

3.3

Patient Review

9/20/2012

Potassium Chloride for Low Amount of Potassium in the Blood

Patient Review

7/7/2018

Potassium Chloride for Low Amount of Potassium in the Blood

The capsules are unfortunately quite large, and I found that this medication also gave me an upset stomach more often than not. It also exacerbated my anxiety levels.

Patient Review

11/20/2012

Potassium Chloride for Low Amount of Potassium in the Blood

2.7

Patient Review

3/24/2021

Potassium Chloride for Low Amount of Potassium in the Blood

Unfortunately, this medication caused me a lot of digestive problems like bloating, gas, and diarrhea. Once I stopped taking it though, everything went back to normal.

2.3

Patient Review

9/19/2013

Potassium Chloride for Low Amount of Potassium in the Blood

After extended hospitalization, I was prescribed this medication. I can't say for certain why, but I suspect it had something to do with my UTI and toxic metabolic encephalopathy.

2.3

Patient Review

11/15/2012

Potassium Chloride for Low Amount of Potassium in the Blood

1.7

Patient Review

5/19/2015

Potassium Chloride for Low Amount of Potassium in the Blood

Can someone please recommend some good oral treatments? Preferably something that will be really helpful.

1.7

Patient Review

12/22/2013

Potassium Chloride for Low Amount of Potassium in the Blood

So far, this medication has been solving the problem it was meant to. My potassium levels were very low and painful before starting this treatment, but now I'm feeling much better.

Patient Review

2/14/2013

Potassium Chloride for Prevention of Low Potassium in the Blood

This caused me a lot of intestinal distress.

Patient Review

12/21/2019

Potassium Chloride for Low Amount of Potassium in the Blood

The tablets are too large for me to take.

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about potassium chloride

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is potassium chloride harmful to the body?

"If you take too much potassium chloride, you may get hyperkalemia, which is a serious condition. Hyperkalemia can cause heart and kidney failure. If you have any symptoms of hyperkalemia or hypokalemia, you should see a doctor right away."

Answered by AI

What does potassium chloride do to your heart?

"Injecting KCl on a regular basis leads to an increase in heart rate and blood pressure."

Answered by AI

What are potassium chloride used for?

"Potassium chloride is a medicine that helps to maintain proper potassium levels in the body. Potassium is a mineral that is important for the proper functioning of the heart, muscles, kidneys, nerves, and digestive system."

Answered by AI

Why is potassium chloride given to patients?

"Potassium chloride is a treatment for low blood levels of potassium (hypokalemia). Low potassium levels can be caused by a disease, certain medications, or prolonged illness with diarrhea or vomiting."

Answered by AI