Partial vs Total Knee Replacement for Osteoarthritis
What You Need to Know Before You Apply
What is the purpose of this trial?
This study is a prospective, randomized trial to compare patient outcomes of unicompartmental knee arthroplasty (UKA) and total knee arthroplasty (TKA) for the treatment of medial compartment osteoarthritis.
Who Is on the Research Team?
Kevin Fricka, MD
Principal Investigator
Anderson Orthopaedic Institute
Are You a Good Fit for This Trial?
This trial is for people with severe osteoarthritis in one part of the knee, who can bend their knee well and don't have too much leg curvature. It's not for those who are very overweight or have diabetes that isn't well-controlled, serious kidney or liver disease, a history of drug abuse, inflammatory arthritis, or past infections in the joint.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Surgery
Participants undergo either unicompartmental knee arthroplasty (UKA) or total knee arthroplasty (TKA)
Follow-up
Participants are monitored for safety and effectiveness after surgery
What Are the Treatments Tested in This Trial?
Interventions
- Total Knee Arthroplasty
- Unicompartmental Knee Arthroplasty
Total Knee Arthroplasty is already approved in European Union, United States, Canada, Japan, China, Switzerland for the following indications:
- Severe knee pain and disability due to rheumatoid arthritis, osteoarthritis, traumatic arthritis, polyarthritis, collagen disorders, and avascular necrosis of the femoral condyle
- Severe knee pain and disability due to degenerative joint disease, rheumatoid arthritis, osteoarthritis, traumatic arthritis, polyarthritis, collagen disorders, and avascular necrosis of the femoral condyle
- Severe knee pain and disability due to degenerative joint disease, rheumatoid arthritis, osteoarthritis, traumatic arthritis, polyarthritis, collagen disorders, and avascular necrosis of the femoral condyle
- Severe knee pain and disability due to degenerative joint disease, rheumatoid arthritis, osteoarthritis, traumatic arthritis, polyarthritis, collagen disorders, and avascular necrosis of the femoral condyle
- Severe knee pain and disability due to degenerative joint disease, rheumatoid arthritis, osteoarthritis, traumatic arthritis, polyarthritis, collagen disorders, and avascular necrosis of the femoral condyle
- Severe knee pain and disability due to degenerative joint disease, rheumatoid arthritis, osteoarthritis, traumatic arthritis, polyarthritis, collagen disorders, and avascular necrosis of the femoral condyle
Find a Clinic Near You
Who Is Running the Clinical Trial?
Anderson Orthopaedic Research Institute
Lead Sponsor
Rush University Medical Center
Collaborator