Pediapred

Stevens-Johnson Syndrome, Ophthalmia, Sympathetic, Chorioretinitis + 103 more

Treatment

4 FDA approvals

20 Active Studies for Pediapred

What is Pediapred

Prednisolone

The Generic name of this drug

Treatment Summary

Prednisolone phosphate is a steroid drug used to reduce inflammation, suppress the immune system, and prevent tumor growth. It was approved by the FDA in 1973 and is similar to cortisol.

Prednisolone

is the brand name

image of different drug pills on a surface

Pediapred Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Prednisolone

Prednisolone

1974

37

Approved as Treatment by the FDA

Prednisolone, otherwise known as Prednisolone, is approved by the FDA for 4 uses including Pneumocystis Jirovecii Pneumonia and Ulcerative Colitis .

Pneumocystis Jirovecii Pneumonia

Used in combination with Dapsone to help manage Pneumocystis Jirovecii Pneumonia

Ulcerative Colitis

Helps manage Ulcerative Colitis

Pneumonia, Pneumocystis

Used in combination with Dapsone to help manage Pneumocystis Jirovecii Pneumonia

Ulcerative Colitis

Helps manage Ulcerative Colitis

Effectiveness

How Pediapred Affects Patients

Prednisolone is a corticosteroid drug that works by blocking pro-inflammatory signals and encouraging anti-inflammatory signals. Its effects do not last very long, as it has a half-life of 2-4 hours. It has a wide range of effective dosages, and much more than what the body would normally produce. Taking this drug carries risks, including weakening the body's natural ability to fight infections and suppressing hormones produced by the hypothalamus, pituitary gland, and adrenal glands.

How Pediapred works in the body

Corticosteroids help reduce inflammation. They work by binding to a receptor in the body that changes the activity of certain genes. Corticosteroids stop white blood cells from accumulating at sites of inflammation, and also stop molecules that cause inflammation from forming. Lower doses of corticosteroids act as an anti-inflammatory, while higher doses reduce the body's immune response. When high doses of corticosteroids are taken for a long period of time, they can cause an imbalance of sodium and potassium levels in the body.

When to interrupt dosage

The recommended dosage of Pediapred is contingent upon the certified situation, including Uveitis, Ocular Inflammation and Ophthalmia, Sympathetic. The amount of dosage fluctuates in accordance with the method of delivery indicated in the table below.

Condition

Dosage

Administration

Communicable Diseases

, 15.0 mg/mL, 25.0 mg/mL, 10.0 mg, 30.0 mg, 15.0 mg, 10.0 mg/mL, 5.0 mg/mL, 5.0 mg/mg, 20.0 mg/mL, 1.2 mg/mL, 5.0 mg, 1.0 mg, 25.0 mg, 20.0 mg, 0.004 mg/mg, 16.7 mg/mL

Ointment - Ophthalmic, , Ophthalmic, Oral, Solution, Solution - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Syrup, Syrup - Oral, Solution / drops - Ophthalmic, Tablet, Tablet - Oral, Solution - Ophthalmic, Suspension - Oral, Suspension / drops - Ophthalmic, Suspension - Ophthalmic, Liquid, Liquid - Oral, Ophthalmic; Topical, Topical, Ointment, Ointment - Topical

Bacterial Infections

, 15.0 mg/mL, 25.0 mg/mL, 10.0 mg, 30.0 mg, 15.0 mg, 10.0 mg/mL, 5.0 mg/mL, 5.0 mg/mg, 20.0 mg/mL, 1.2 mg/mL, 5.0 mg, 1.0 mg, 25.0 mg, 20.0 mg, 0.004 mg/mg, 16.7 mg/mL

Ointment - Ophthalmic, , Ophthalmic, Oral, Solution, Solution - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Syrup, Syrup - Oral, Solution / drops - Ophthalmic, Tablet, Tablet - Oral, Solution - Ophthalmic, Suspension - Oral, Suspension / drops - Ophthalmic, Suspension - Ophthalmic, Liquid, Liquid - Oral, Ophthalmic; Topical, Topical, Ointment, Ointment - Topical

Brain

, 15.0 mg/mL, 25.0 mg/mL, 10.0 mg, 30.0 mg, 15.0 mg, 10.0 mg/mL, 5.0 mg/mL, 5.0 mg/mg, 20.0 mg/mL, 1.2 mg/mL, 5.0 mg, 1.0 mg, 25.0 mg, 20.0 mg, 0.004 mg/mg, 16.7 mg/mL

Ointment - Ophthalmic, , Ophthalmic, Oral, Solution, Solution - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Syrup, Syrup - Oral, Solution / drops - Ophthalmic, Tablet, Tablet - Oral, Solution - Ophthalmic, Suspension - Oral, Suspension / drops - Ophthalmic, Suspension - Ophthalmic, Liquid, Liquid - Oral, Ophthalmic; Topical, Topical, Ointment, Ointment - Topical

Rheumatoid Arthritis

, 15.0 mg/mL, 25.0 mg/mL, 10.0 mg, 30.0 mg, 15.0 mg, 10.0 mg/mL, 5.0 mg/mL, 5.0 mg/mg, 20.0 mg/mL, 1.2 mg/mL, 5.0 mg, 1.0 mg, 25.0 mg, 20.0 mg, 0.004 mg/mg, 16.7 mg/mL

Ointment - Ophthalmic, , Ophthalmic, Oral, Solution, Solution - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Syrup, Syrup - Oral, Solution / drops - Ophthalmic, Tablet, Tablet - Oral, Solution - Ophthalmic, Suspension - Oral, Suspension / drops - Ophthalmic, Suspension - Ophthalmic, Liquid, Liquid - Oral, Ophthalmic; Topical, Topical, Ointment, Ointment - Topical

Tuberculosis

, 15.0 mg/mL, 25.0 mg/mL, 10.0 mg, 30.0 mg, 15.0 mg, 10.0 mg/mL, 5.0 mg/mL, 5.0 mg/mg, 20.0 mg/mL, 1.2 mg/mL, 5.0 mg, 1.0 mg, 25.0 mg, 20.0 mg, 0.004 mg/mg, 16.7 mg/mL

Ointment - Ophthalmic, , Ophthalmic, Oral, Solution, Solution - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Syrup, Syrup - Oral, Solution / drops - Ophthalmic, Tablet, Tablet - Oral, Solution - Ophthalmic, Suspension - Oral, Suspension / drops - Ophthalmic, Suspension - Ophthalmic, Liquid, Liquid - Oral, Ophthalmic; Topical, Topical, Ointment, Ointment - Topical

Arthritis, Juvenile

, 15.0 mg/mL, 25.0 mg/mL, 10.0 mg, 30.0 mg, 15.0 mg, 10.0 mg/mL, 5.0 mg/mL, 5.0 mg/mg, 20.0 mg/mL, 1.2 mg/mL, 5.0 mg, 1.0 mg, 25.0 mg, 20.0 mg, 0.004 mg/mg, 16.7 mg/mL

Ointment - Ophthalmic, , Ophthalmic, Oral, Solution, Solution - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Syrup, Syrup - Oral, Solution / drops - Ophthalmic, Tablet, Tablet - Oral, Solution - Ophthalmic, Suspension - Oral, Suspension / drops - Ophthalmic, Suspension - Ophthalmic, Liquid, Liquid - Oral, Ophthalmic; Topical, Topical, Ointment, Ointment - Topical

Aspergillosis, Allergic Bronchopulmonary

, 15.0 mg/mL, 25.0 mg/mL, 10.0 mg, 30.0 mg, 15.0 mg, 10.0 mg/mL, 5.0 mg/mL, 5.0 mg/mg, 20.0 mg/mL, 1.2 mg/mL, 5.0 mg, 1.0 mg, 25.0 mg, 20.0 mg, 0.004 mg/mg, 16.7 mg/mL

Ointment - Ophthalmic, , Ophthalmic, Oral, Solution, Solution - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Syrup, Syrup - Oral, Solution / drops - Ophthalmic, Tablet, Tablet - Oral, Solution - Ophthalmic, Suspension - Oral, Suspension / drops - Ophthalmic, Suspension - Ophthalmic, Liquid, Liquid - Oral, Ophthalmic; Topical, Topical, Ointment, Ointment - Topical

Trichinosis

, 15.0 mg/mL, 25.0 mg/mL, 10.0 mg, 30.0 mg, 15.0 mg, 10.0 mg/mL, 5.0 mg/mL, 5.0 mg/mg, 20.0 mg/mL, 1.2 mg/mL, 5.0 mg, 1.0 mg, 25.0 mg, 20.0 mg, 0.004 mg/mg, 16.7 mg/mL

Ointment - Ophthalmic, , Ophthalmic, Oral, Solution, Solution - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Syrup, Syrup - Oral, Solution / drops - Ophthalmic, Tablet, Tablet - Oral, Solution - Ophthalmic, Suspension - Oral, Suspension / drops - Ophthalmic, Suspension - Ophthalmic, Liquid, Liquid - Oral, Ophthalmic; Topical, Topical, Ointment, Ointment - Topical

Red-Cell Aplasia, Pure

, 15.0 mg/mL, 25.0 mg/mL, 10.0 mg, 30.0 mg, 15.0 mg, 10.0 mg/mL, 5.0 mg/mL, 5.0 mg/mg, 20.0 mg/mL, 1.2 mg/mL, 5.0 mg, 1.0 mg, 25.0 mg, 20.0 mg, 0.004 mg/mg, 16.7 mg/mL

Ointment - Ophthalmic, , Ophthalmic, Oral, Solution, Solution - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Syrup, Syrup - Oral, Solution / drops - Ophthalmic, Tablet, Tablet - Oral, Solution - Ophthalmic, Suspension - Oral, Suspension / drops - Ophthalmic, Suspension - Ophthalmic, Liquid, Liquid - Oral, Ophthalmic; Topical, Topical, Ointment, Ointment - Topical

Ulcerative Colitis

, 15.0 mg/mL, 25.0 mg/mL, 10.0 mg, 30.0 mg, 15.0 mg, 10.0 mg/mL, 5.0 mg/mL, 5.0 mg/mg, 20.0 mg/mL, 1.2 mg/mL, 5.0 mg, 1.0 mg, 25.0 mg, 20.0 mg, 0.004 mg/mg, 16.7 mg/mL

Ointment - Ophthalmic, , Ophthalmic, Oral, Solution, Solution - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Syrup, Syrup - Oral, Solution / drops - Ophthalmic, Tablet, Tablet - Oral, Solution - Ophthalmic, Suspension - Oral, Suspension / drops - Ophthalmic, Suspension - Ophthalmic, Liquid, Liquid - Oral, Ophthalmic; Topical, Topical, Ointment, Ointment - Topical

Lupus

, 15.0 mg/mL, 25.0 mg/mL, 10.0 mg, 30.0 mg, 15.0 mg, 10.0 mg/mL, 5.0 mg/mL, 5.0 mg/mg, 20.0 mg/mL, 1.2 mg/mL, 5.0 mg, 1.0 mg, 25.0 mg, 20.0 mg, 0.004 mg/mg, 16.7 mg/mL

Ointment - Ophthalmic, , Ophthalmic, Oral, Solution, Solution - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Syrup, Syrup - Oral, Solution / drops - Ophthalmic, Tablet, Tablet - Oral, Solution - Ophthalmic, Suspension - Oral, Suspension / drops - Ophthalmic, Suspension - Ophthalmic, Liquid, Liquid - Oral, Ophthalmic; Topical, Topical, Ointment, Ointment - Topical

Relapsing Polychondritis

, 15.0 mg/mL, 25.0 mg/mL, 10.0 mg, 30.0 mg, 15.0 mg, 10.0 mg/mL, 5.0 mg/mL, 5.0 mg/mg, 20.0 mg/mL, 1.2 mg/mL, 5.0 mg, 1.0 mg, 25.0 mg, 20.0 mg, 0.004 mg/mg, 16.7 mg/mL

Ointment - Ophthalmic, , Ophthalmic, Oral, Solution, Solution - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Syrup, Syrup - Oral, Solution / drops - Ophthalmic, Tablet, Tablet - Oral, Solution - Ophthalmic, Suspension - Oral, Suspension / drops - Ophthalmic, Suspension - Ophthalmic, Liquid, Liquid - Oral, Ophthalmic; Topical, Topical, Ointment, Ointment - Topical

Anemia, Diamond-Blackfan

, 15.0 mg/mL, 25.0 mg/mL, 10.0 mg, 30.0 mg, 15.0 mg, 10.0 mg/mL, 5.0 mg/mL, 5.0 mg/mg, 20.0 mg/mL, 1.2 mg/mL, 5.0 mg, 1.0 mg, 25.0 mg, 20.0 mg, 0.004 mg/mg, 16.7 mg/mL

Ointment - Ophthalmic, , Ophthalmic, Oral, Solution, Solution - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Syrup, Syrup - Oral, Solution / drops - Ophthalmic, Tablet, Tablet - Oral, Solution - Ophthalmic, Suspension - Oral, Suspension / drops - Ophthalmic, Suspension - Ophthalmic, Liquid, Liquid - Oral, Ophthalmic; Topical, Topical, Ointment, Ointment - Topical

Thyroiditis

, 15.0 mg/mL, 25.0 mg/mL, 10.0 mg, 30.0 mg, 15.0 mg, 10.0 mg/mL, 5.0 mg/mL, 5.0 mg/mg, 20.0 mg/mL, 1.2 mg/mL, 5.0 mg, 1.0 mg, 25.0 mg, 20.0 mg, 0.004 mg/mg, 16.7 mg/mL

Ointment - Ophthalmic, , Ophthalmic, Oral, Solution, Solution - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Syrup, Syrup - Oral, Solution / drops - Ophthalmic, Tablet, Tablet - Oral, Solution - Ophthalmic, Suspension - Oral, Suspension / drops - Ophthalmic, Suspension - Ophthalmic, Liquid, Liquid - Oral, Ophthalmic; Topical, Topical, Ointment, Ointment - Topical

Thrombocytopenia

, 15.0 mg/mL, 25.0 mg/mL, 10.0 mg, 30.0 mg, 15.0 mg, 10.0 mg/mL, 5.0 mg/mL, 5.0 mg/mg, 20.0 mg/mL, 1.2 mg/mL, 5.0 mg, 1.0 mg, 25.0 mg, 20.0 mg, 0.004 mg/mg, 16.7 mg/mL

Ointment - Ophthalmic, , Ophthalmic, Oral, Solution, Solution - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Syrup, Syrup - Oral, Solution / drops - Ophthalmic, Tablet, Tablet - Oral, Solution - Ophthalmic, Suspension - Oral, Suspension / drops - Ophthalmic, Suspension - Ophthalmic, Liquid, Liquid - Oral, Ophthalmic; Topical, Topical, Ointment, Ointment - Topical

Corneal Injuries

, 15.0 mg/mL, 25.0 mg/mL, 10.0 mg, 30.0 mg, 15.0 mg, 10.0 mg/mL, 5.0 mg/mL, 5.0 mg/mg, 20.0 mg/mL, 1.2 mg/mL, 5.0 mg, 1.0 mg, 25.0 mg, 20.0 mg, 0.004 mg/mg, 16.7 mg/mL

Ointment - Ophthalmic, , Ophthalmic, Oral, Solution, Solution - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Syrup, Syrup - Oral, Solution / drops - Ophthalmic, Tablet, Tablet - Oral, Solution - Ophthalmic, Suspension - Oral, Suspension / drops - Ophthalmic, Suspension - Ophthalmic, Liquid, Liquid - Oral, Ophthalmic; Topical, Topical, Ointment, Ointment - Topical

Dermatomyositis

, 15.0 mg/mL, 25.0 mg/mL, 10.0 mg, 30.0 mg, 15.0 mg, 10.0 mg/mL, 5.0 mg/mL, 5.0 mg/mg, 20.0 mg/mL, 1.2 mg/mL, 5.0 mg, 1.0 mg, 25.0 mg, 20.0 mg, 0.004 mg/mg, 16.7 mg/mL

Ointment - Ophthalmic, , Ophthalmic, Oral, Solution, Solution - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Syrup, Syrup - Oral, Solution / drops - Ophthalmic, Tablet, Tablet - Oral, Solution - Ophthalmic, Suspension - Oral, Suspension / drops - Ophthalmic, Suspension - Ophthalmic, Liquid, Liquid - Oral, Ophthalmic; Topical, Topical, Ointment, Ointment - Topical

Optic Neuritis

, 15.0 mg/mL, 25.0 mg/mL, 10.0 mg, 30.0 mg, 15.0 mg, 10.0 mg/mL, 5.0 mg/mL, 5.0 mg/mg, 20.0 mg/mL, 1.2 mg/mL, 5.0 mg, 1.0 mg, 25.0 mg, 20.0 mg, 0.004 mg/mg, 16.7 mg/mL

Ointment - Ophthalmic, , Ophthalmic, Oral, Solution, Solution - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Syrup, Syrup - Oral, Solution / drops - Ophthalmic, Tablet, Tablet - Oral, Solution - Ophthalmic, Suspension - Oral, Suspension / drops - Ophthalmic, Suspension - Ophthalmic, Liquid, Liquid - Oral, Ophthalmic; Topical, Topical, Ointment, Ointment - Topical

Proctitis

, 15.0 mg/mL, 25.0 mg/mL, 10.0 mg, 30.0 mg, 15.0 mg, 10.0 mg/mL, 5.0 mg/mL, 5.0 mg/mg, 20.0 mg/mL, 1.2 mg/mL, 5.0 mg, 1.0 mg, 25.0 mg, 20.0 mg, 0.004 mg/mg, 16.7 mg/mL

Ointment - Ophthalmic, , Ophthalmic, Oral, Solution, Solution - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Syrup, Syrup - Oral, Solution / drops - Ophthalmic, Tablet, Tablet - Oral, Solution - Ophthalmic, Suspension - Oral, Suspension / drops - Ophthalmic, Suspension - Ophthalmic, Liquid, Liquid - Oral, Ophthalmic; Topical, Topical, Ointment, Ointment - Topical

Anemia, Hemolytic

, 15.0 mg/mL, 25.0 mg/mL, 10.0 mg, 30.0 mg, 15.0 mg, 10.0 mg/mL, 5.0 mg/mL, 5.0 mg/mg, 20.0 mg/mL, 1.2 mg/mL, 5.0 mg, 1.0 mg, 25.0 mg, 20.0 mg, 0.004 mg/mg, 16.7 mg/mL

Ointment - Ophthalmic, , Ophthalmic, Oral, Solution, Solution - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Syrup, Syrup - Oral, Solution / drops - Ophthalmic, Tablet, Tablet - Oral, Solution - Ophthalmic, Suspension - Oral, Suspension / drops - Ophthalmic, Suspension - Ophthalmic, Liquid, Liquid - Oral, Ophthalmic; Topical, Topical, Ointment, Ointment - Topical

Warnings

Pediapred Contraindications

Condition

Risk Level

Notes

Severe Hypersensitivity Reactions

Do Not Combine

Prednisolone may interact with Pulse Frequency

There are 20 known major drug interactions with Pediapred.

Common Pediapred Drug Interactions

Drug Name

Risk Level

Description

2-Methoxyethanol

Major

The risk or severity of adverse effects can be increased when Prednisolone is combined with 2-Methoxyethanol.

9-(N-methyl-L-isoleucine)-cyclosporin A

Major

The risk or severity of adverse effects can be increased when Prednisolone is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.

Abatacept

Major

The risk or severity of adverse effects can be increased when Prednisolone is combined with Abatacept.

Abemaciclib

Major

The metabolism of Abemaciclib can be increased when combined with Prednisolone.

Abetimus

Major

The risk or severity of adverse effects can be increased when Prednisolone is combined with Abetimus.

Pediapred Toxicity & Overdose Risk

Not much is known about overdosing on prednisone, but those who take too much for a long period of time may show signs such as confusion, a round face, extra fat deposits, and water retention. If someone has taken too much prednisone orally, they should be given their stomach pumped or made to vomit. If someone has been taking too much prednisone for a long time, their dosage should be lowered or taken every other day.

image of a doctor in a lab doing drug, clinical research

Pediapred Novel Uses: Which Conditions Have a Clinical Trial Featuring Pediapred?

115 active clinical trials are currently in progress to examine the potential of Pediapred in alleviating Ocular Inflammation, Uveitis, Sympathetic Ophthalmia and other conditions.

Condition

Clinical Trials

Trial Phases

Red-Cell Aplasia, Pure

0 Actively Recruiting

Dermatitis, Allergic Contact

0 Actively Recruiting

Asthma

0 Actively Recruiting

Ulcerative Colitis

14 Actively Recruiting

Phase 3, Phase 2, Not Applicable, Phase 4, Phase 1

Hot Water Burns (Scalds)

0 Actively Recruiting

Anemia, Diamond-Blackfan

4 Actively Recruiting

Not Applicable, Phase 1, Phase 2

Lupus

65 Actively Recruiting

Phase 2, Not Applicable, Phase 1, Phase 3, Phase 4, Early Phase 1

Mycosis Fungoides

0 Actively Recruiting

Degenerative polyarthritis

13 Actively Recruiting

Not Applicable, Early Phase 1, Phase 3, Phase 2

Nephrotic Syndrome

5 Actively Recruiting

Phase 2, Not Applicable, Phase 3

Sarcoidosis

10 Actively Recruiting

Phase 4, Phase 2, Not Applicable, Phase 3

Thrombocytopenia

0 Actively Recruiting

Brain

0 Actively Recruiting

Dermatomyositis

0 Actively Recruiting

Eosinophilic Pneumonia

0 Actively Recruiting

Organ Transplantation

0 Actively Recruiting

Congenital adrenal hyperplasia

7 Actively Recruiting

Phase 3, Phase 1, Phase 2, Not Applicable

Eczema

0 Actively Recruiting

Eczema

0 Actively Recruiting

Pemphigus

0 Actively Recruiting

Pediapred Reviews: What are patients saying about Pediapred?

4

Patient Review

2/12/2008

Pediapred for Asthma

My 3 year old takes this for asthma/wheezing/breathing problems. The only problem I've had with it is that is makes him very cranky & grouchy, more so than a 3 year old would usually be.

4

Patient Review

12/14/2008

Pediapred for Asthma

This medicine is great! My 6 year old daughter uses this to treat her asthma attacks and I have never found anything else that works this well. The only complaint that I have is it tastes horrible. Other than it making her hungry and a little on the touchy side (cries at the littlest things) this medicine is wonderful.

3.3

Patient Review

12/18/2009

Pediapred for Asthma

While this medicine did reduce my 1 year old's slight wheezing, it also gave him a terrible case of thrush and a yeast infection that was even more painful, and long lasting.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about pediapred

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is Pediapred liquid?

"PEDIAPRED® Oral Solution is a colorless to light straw-colored, raspberry flavored solution. Each 5 mL (teaspoonful) of PEDIAPRED® Oral Solution contains 6.7 mg PEDIAPRED® (5 mg prednisolone base) in a palatable, aqueous vehicle."

Answered by AI

What is prednisolone prescribed for?

"Prednisolone is a medicine that is used to treat various health conditions. These health conditions include allergies, blood disorders, skin diseases, inflammation, infections, and certain cancers. Prednisolone can also help to prevent organ rejection after a transplant. This medicine works by reducing swelling (inflammation). Prednisolone can also help to calm down your immune system."

Answered by AI

How long does it take for Pediapred to work?

"It usually takes 3 to 10 days to treat this, although it can take longer."

Answered by AI

What is Pediapred used for?

"This drug is used to treat a variety of conditions, including arthritis, blood disorders, immune system disorders, skin and eye conditions, breathing problems, cancer, and severe allergies. It works by decreasing the immune system's response to diseases, which decreases symptoms such as pain, swelling, and allergic reactions."

Answered by AI

Clinical Trials for Pediapred

Image of McMaster Children's Hospital - Digestive Diseases Clinic in Hamilton, Canada.

Vancomycin for Ulcerative Colitis

18+
All Sexes
Hamilton, Canada

This clinical trial tests if oral vancomycin can safely treat active ulcerative colitis (UC) in adults who also have primary sclerosing cholangitis (PSC), a liver condition. The main questions it aims to answer are: * Can oral vancomycin improve UC symptoms as measured by Mayo score at 4 weeks? * Is oral vancomycin safe and tolerable in this patient group? Participants will be compared to see if vancomycin works better than placebo. Participants will: * Take oral vancomycin (250 mg twice daily) or identical placebo capsules for 4 weeks * Have the option for 4 more weeks of open-label vancomycin after the blinded phase * Attend clinic visits at baseline, week 4, and follow-up for Mayo scoring, endoscopy, blood/stool tests, and safety checks * Track treatment adherence and side effects The study primarily assesses if the trial can recruit 14 participants, retain them, achieve good adherence, and follow protocol procedures (feasibility). Secondary goals include safety (adverse events) and early signs of benefit in UC activity, liver tests, and gut bacteria balance. This pilot will guide larger future studies.

Phase 2
Waitlist Available

McMaster Children's Hospital - Digestive Diseases Clinic

Neeraj Narula, MD

Image of McGill university Health Centre (Royal victoria Hospital and Montreal General Hospital in Montreal, Canada.

Systemic Corticosteroids for Pneumocystis Pneumonia

18+
All Sexes
Montreal, Canada

The HOW LONG trial is an international, multicenter, Phase IV randomized clinical trial evaluating the optimal duration of adjunctive systemic corticosteroids in immunocompromised adults with severe Pneumocystis jirovecii pneumonia (PCP) who demonstrate early clinical recovery. Participants who no longer require supplemental oxygen by day 10 of corticosteroid therapy are randomized to discontinue corticosteroids at day 10 (or hospital discharge, if earlier) versus continue corticosteroids for a total of 21 days. The trial assesses whether earlier discontinuation reduces steroid-related complications while maintaining clinical outcomes.

Phase 4
Waitlist Available

McGill university Health Centre (Royal victoria Hospital and Montreal General Hospital

Have you considered Pediapred clinical trials?

We made a collection of clinical trials featuring Pediapred, we think they might fit your search criteria.
Go to Trials
Image of Johns Hopkins Bayview Medical Center in Baltimore, United States.

VR-Enhanced PMR for Post-Burn Symptoms

18+
All Sexes
Baltimore, MD

The goal of this clinical trial is to learn whether progressive muscle relaxation (PMR), delivered either alone or enhanced with virtual reality (VR), can help treat chronic symptom, such as pain, itch, anxiety, sleep disturbances, and fatigue, in adult burn survivors. The main questions it aims to answer are: * Does VR-enhanced PMR (VR-PMR) reduce chronic pain, anxiety, itch, sleep disturbances, and fatigue more effectively than standard PMR? * Is VR-PMR a feasible and acceptable self-administered home-based intervention for burn survivors? Researchers will compare two self-administered intervention conditions, VR-enhanced PMR and standard PMR, using a randomized to sequence crossover design to see if VR technology enhances the therapeutic effects of PMR on chronic symptom management in burn survivors. Participants will: * Complete home-based sessions of VR-enhanced PMR * Complete home-based sessions of standard PMR * Report symptoms such as pain, itch, anxiety, sleep disturbances, and fatigue throughout the study * Use VR equipment provided for the intervention period (during the VR-PMR arm)

Recruiting
Has No Placebo

Johns Hopkins Bayview Medical Center

Sheera Lerman Zohar, PhD

Image of The University of British Columbia in Vancouver, Canada.

Nutritional Therapy + Anti-TNFα for Crohn's Disease

9 - 17
All Sexes
Vancouver, Canada

Children with Crohn's disease (CD), a type of Inflammatory Bowel Disease (IBD), often face serious health challenges, including poor growth, frequent hospital stays, and long-term medication use. Although biologic drugs like infliximab, an anti-TNFα (Tumor necrosis factor α) medication, have improved treatment, they don't work for everyone: many children still experience symptoms or disease flare-ups. Nutritional therapies, especially the Crohn's Disease Exclusion Diet (CDED), may help improve treatment outcomes. This study will assess whether starting CDED at the same time as infliximab leads to better responses to treatment. The goal of this study is to improve how well children respond to therapy, reduce drug exposure, and support better long-term health.

Waitlist Available
Has No Placebo

The University of British Columbia

Kevan Jacobson, MBBCh, FRCP, FRCPC, AGAF, CAGF

Image of National Institutes of Health Clinical Center in Bethesda, United States.

Meal Macronutrients for Blood Fat Levels

18 - 120
All Sexes
Bethesda, MD

Background: Abnormal fats in the blood can lead to many problems, including heart disease. Researchers want to learn more about how eating meals with different levels of nutrients affects fats in the blood. Specifically, they want to study people with too much body fat, too little body fat, and a kidney problem called nephrotic syndrome. Objective: To learn more about how different types of foods affect fat levels in the blood. Eligibility: People aged 18 years or older with a health condition that affects how their body handles fats. Healthy volunteers are also needed. Design: Participants will have 2 overnight stays in the clinic within 6 months. At each visit, after staying overnight, they will eat a breakfast casserole. At 1 visit, breakfast will be a high-fat, low carbohydrate meal. At the other, it will be a high-carbohydrate, low-fat meal. Participants will have a tube inserted into a vein in their arm. They will have blood drawn via the tube 12 times in 8 hours: 2 times before they eat the breakfast and 10 times after. Participants will have other tests during their stays: * A resting metabolic test captures the air they exhale and measures how much energy they use at rest. * A dual energy X-ray absorptiometry (DXA) scan measures how much fat and muscle they have. * A Fibroscan is a special type of ultrasound of the liver. * A body surface scan uses lasers to measure the total area of the body. * A bioelectric impedance (BIS) exam measures how fast small electric currents move through their body. Participants may opt to have a third visit. At this visit, the breakfast will be high in protein.

Phase 2
Waitlist Available

National Institutes of Health Clinical Center

Rebecca J Brown, M.D.

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