Ortho-Cept

Birth Control, Acne Vulgaris, Folate supplementation therapy + 5 more
Treatment
1 FDA approval
20 Active Studies for Ortho-Cept

What is Ortho-Cept

EthinylestradiolThe Generic name of this drug
Treatment SummaryEthinylestradiol is an estrogen-based drug first developed in 1938 by Hans Herloff Inhoffen and Walter Hohlweg at Schering. The drug was designed to have a higher bioavailability when taken orally than other estrogens. Ethinylestradiol is primarily used in birth control pills and was approved by the FDA in 1943.
LOESTRIN Fe 1.5/30is the brand name
image of different drug pills on a surface
Ortho-Cept Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
LOESTRIN Fe 1.5/30
Ethinylestradiol
1973
679

Approved as Treatment by the FDA

Ethinylestradiol, also known as LOESTRIN Fe 1.5/30, is approved by the FDA for 1 uses including Birth Control .
Birth Control
Used to treat Contraception in combination with Levonorgestrel

Effectiveness

How Ortho-Cept Affects PatientsEthinylestradiol is a synthetic form of estrogen used to prevent ovulation. Patients take it once a day and usually don't experience serious side effects if they take too much. However, they should be aware that it can increase their risk of thrombotic events.
How Ortho-Cept works in the bodyEthinylestradiol is a synthetic hormone used in some birth control pills. It works to reduce ovulation and make it harder for sperm to reach an egg. It also thickens cervical mucus, which prevents sperm from entering the uterus. Ethinylestradiol can also reduce bone density and reduce the hormones that cause the uterus to get ready for a fertilized egg. It also increases the amount of a protein that helps bind hormones in the body.

When to interrupt dosage

The amount of Ortho-Cept is contingent upon the determined condition, such as Acne Vulgaris, Hormonal Contraception and Folate supplementation therapy. The measure of dosage can be sourced in the table beneath, based on the technique of delivery.
Condition
Dosage
Administration
Birth Control
, 0.02 mg, 0.0025 mg, 0.03 mg, 0.0035 mg/hour, 0.005 mg, 2.7 mg, 0.035 mg, 0.6 mg, 2.6 mg, 0.05 mg, 0.5 mg, 0.75 mg, 0.025 mg, 0.0015 mg/hour, 0.04 mg, 0.01 mg, 1.0 mg, 0.075 mg, 0.105 mg, 0.07 mg, 0.1 mg, 0.75 mg/[USP'U], 0.0075 mg/hour, 17.4 mg, 0.085 mg, 2.3 mg
, Kit, Tablet - Oral, Oral, Tablet, Kit - Oral, Patch, extended release, Patch, extended release - Transdermal, Transdermal, Insert, extended release, Vaginal, Insert, extended release - Vaginal, Ring - Vaginal, Ring, Tablet, chewable, Tablet, chewable - Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Transdermal, Capsule, Capsule - Oral
Mild to Moderate Acne
, 0.02 mg, 0.0025 mg, 0.03 mg, 0.0035 mg/hour, 0.005 mg, 2.7 mg, 0.035 mg, 0.6 mg, 2.6 mg, 0.05 mg, 0.5 mg, 0.75 mg, 0.025 mg, 0.0015 mg/hour, 0.04 mg, 0.01 mg, 1.0 mg, 0.075 mg, 0.105 mg, 0.07 mg, 0.1 mg, 0.75 mg/[USP'U], 0.0075 mg/hour, 17.4 mg, 0.085 mg, 2.3 mg
, Kit, Tablet - Oral, Oral, Tablet, Kit - Oral, Patch, extended release, Patch, extended release - Transdermal, Transdermal, Insert, extended release, Vaginal, Insert, extended release - Vaginal, Ring - Vaginal, Ring, Tablet, chewable, Tablet, chewable - Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Transdermal, Capsule, Capsule - Oral
Menopausal Osteoporosis
, 0.02 mg, 0.0025 mg, 0.03 mg, 0.0035 mg/hour, 0.005 mg, 2.7 mg, 0.035 mg, 0.6 mg, 2.6 mg, 0.05 mg, 0.5 mg, 0.75 mg, 0.025 mg, 0.0015 mg/hour, 0.04 mg, 0.01 mg, 1.0 mg, 0.075 mg, 0.105 mg, 0.07 mg, 0.1 mg, 0.75 mg/[USP'U], 0.0075 mg/hour, 17.4 mg, 0.085 mg, 2.3 mg
, Kit, Tablet - Oral, Oral, Tablet, Kit - Oral, Patch, extended release, Patch, extended release - Transdermal, Transdermal, Insert, extended release, Vaginal, Insert, extended release - Vaginal, Ring - Vaginal, Ring, Tablet, chewable, Tablet, chewable - Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Transdermal, Capsule, Capsule - Oral
Patient desires oral contraception for birth control
, 0.02 mg, 0.0025 mg, 0.03 mg, 0.0035 mg/hour, 0.005 mg, 2.7 mg, 0.035 mg, 0.6 mg, 2.6 mg, 0.05 mg, 0.5 mg, 0.75 mg, 0.025 mg, 0.0015 mg/hour, 0.04 mg, 0.01 mg, 1.0 mg, 0.075 mg, 0.105 mg, 0.07 mg, 0.1 mg, 0.75 mg/[USP'U], 0.0075 mg/hour, 17.4 mg, 0.085 mg, 2.3 mg
, Kit, Tablet - Oral, Oral, Tablet, Kit - Oral, Patch, extended release, Patch, extended release - Transdermal, Transdermal, Insert, extended release, Vaginal, Insert, extended release - Vaginal, Ring - Vaginal, Ring, Tablet, chewable, Tablet, chewable - Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Transdermal, Capsule, Capsule - Oral
Acne Vulgaris
, 0.02 mg, 0.0025 mg, 0.03 mg, 0.0035 mg/hour, 0.005 mg, 2.7 mg, 0.035 mg, 0.6 mg, 2.6 mg, 0.05 mg, 0.5 mg, 0.75 mg, 0.025 mg, 0.0015 mg/hour, 0.04 mg, 0.01 mg, 1.0 mg, 0.075 mg, 0.105 mg, 0.07 mg, 0.1 mg, 0.75 mg/[USP'U], 0.0075 mg/hour, 17.4 mg, 0.085 mg, 2.3 mg
, Kit, Tablet - Oral, Oral, Tablet, Kit - Oral, Patch, extended release, Patch, extended release - Transdermal, Transdermal, Insert, extended release, Vaginal, Insert, extended release - Vaginal, Ring - Vaginal, Ring, Tablet, chewable, Tablet, chewable - Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Transdermal, Capsule, Capsule - Oral
Folate supplementation therapy
, 0.02 mg, 0.0025 mg, 0.03 mg, 0.0035 mg/hour, 0.005 mg, 2.7 mg, 0.035 mg, 0.6 mg, 2.6 mg, 0.05 mg, 0.5 mg, 0.75 mg, 0.025 mg, 0.0015 mg/hour, 0.04 mg, 0.01 mg, 1.0 mg, 0.075 mg, 0.105 mg, 0.07 mg, 0.1 mg, 0.75 mg/[USP'U], 0.0075 mg/hour, 17.4 mg, 0.085 mg, 2.3 mg
, Kit, Tablet - Oral, Oral, Tablet, Kit - Oral, Patch, extended release, Patch, extended release - Transdermal, Transdermal, Insert, extended release, Vaginal, Insert, extended release - Vaginal, Ring - Vaginal, Ring, Tablet, chewable, Tablet, chewable - Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Transdermal, Capsule, Capsule - Oral
Hormonal Contraception
, 0.02 mg, 0.0025 mg, 0.03 mg, 0.0035 mg/hour, 0.005 mg, 2.7 mg, 0.035 mg, 0.6 mg, 2.6 mg, 0.05 mg, 0.5 mg, 0.75 mg, 0.025 mg, 0.0015 mg/hour, 0.04 mg, 0.01 mg, 1.0 mg, 0.075 mg, 0.105 mg, 0.07 mg, 0.1 mg, 0.75 mg/[USP'U], 0.0075 mg/hour, 17.4 mg, 0.085 mg, 2.3 mg
, Kit, Tablet - Oral, Oral, Tablet, Kit - Oral, Patch, extended release, Patch, extended release - Transdermal, Transdermal, Insert, extended release, Vaginal, Insert, extended release - Vaginal, Ring - Vaginal, Ring, Tablet, chewable, Tablet, chewable - Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Transdermal, Capsule, Capsule - Oral
Menopause
, 0.02 mg, 0.0025 mg, 0.03 mg, 0.0035 mg/hour, 0.005 mg, 2.7 mg, 0.035 mg, 0.6 mg, 2.6 mg, 0.05 mg, 0.5 mg, 0.75 mg, 0.025 mg, 0.0015 mg/hour, 0.04 mg, 0.01 mg, 1.0 mg, 0.075 mg, 0.105 mg, 0.07 mg, 0.1 mg, 0.75 mg/[USP'U], 0.0075 mg/hour, 17.4 mg, 0.085 mg, 2.3 mg
, Kit, Tablet - Oral, Oral, Tablet, Kit - Oral, Patch, extended release, Patch, extended release - Transdermal, Transdermal, Insert, extended release, Vaginal, Insert, extended release - Vaginal, Ring - Vaginal, Ring, Tablet, chewable, Tablet, chewable - Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Transdermal, Capsule, Capsule - Oral

Warnings

Ortho-Cept has twenty-six counterindications, so it should not be used when encountering any of the conditions listed in the following table.Ortho-Cept Contraindications
Condition
Risk Level
Notes
Heavy Smoking
Do Not Combine
Metrorrhagia
Do Not Combine
estrogen-sensitive cancer
Do Not Combine
Thrombophlebitis
Do Not Combine
high risk of venous thrombotic disease
Do Not Combine
history of deep venous thrombosis
Do Not Combine
Pulse Frequency
Do Not Combine
Breast
Do Not Combine
Coronary Artery Disease
Do Not Combine
high risk of arterial thrombotic disease
Do Not Combine
Thromboembolism
Do Not Combine
Coronary Artery Disease (CAD)
Do Not Combine
Hypersensitivity
Do Not Combine
Pulse Frequency
Do Not Combine
Adrenal Insufficiency
Do Not Combine
major surgery with prolonged immobilization
Do Not Combine
Pulse Frequency
Do Not Combine
Severe Hypertension
Do Not Combine
undiagnosed abnormal genital bleeding
Do Not Combine
Breast Cancer
Do Not Combine
Neoplasms, Hepatic
Do Not Combine
Deep Vein Thrombosis
Do Not Combine
Decompensated Cirrhosis
Do Not Combine
Breast
Do Not Combine
Impaired Renal Function
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Ethinylestradiol may interact with Pulse Frequency
There are 20 known major drug interactions with Ortho-Cept.
Common Ortho-Cept Drug Interactions
Drug Name
Risk Level
Description
Anastrozole
Major
The therapeutic efficacy of Anastrozole can be decreased when used in combination with Ethinylestradiol.
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Ethinylestradiol.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Ethinylestradiol.
Belinostat
Major
The metabolism of Belinostat can be increased when combined with Ethinylestradiol.
Binimetinib
Major
The metabolism of Binimetinib can be increased when combined with Ethinylestradiol.
Ortho-Cept Toxicity & Overdose RiskWomen who overdose on this drug may experience bleeding, nausea, vomiting, breast tenderness, abdominal pain, drowsiness, and fatigue. Treatment should include supportive care, such as monitoring potassium and sodium levels and looking for signs of acidosis.
image of a doctor in a lab doing drug, clinical research

Ortho-Cept Novel Uses: Which Conditions Have a Clinical Trial Featuring Ortho-Cept?

Currently, 38 active studies are investigating the potential of Ortho-Cept to provide Folate supplementation therapy, ameliorate Premenstrual Dysphoric Disorder and Menopause symptoms.
Condition
Clinical Trials
Trial Phases
Birth Control
31 Actively Recruiting
Not Applicable, Phase 3, Phase 4, Early Phase 1
Patient desires oral contraception for birth control
0 Actively Recruiting
Folate supplementation therapy
0 Actively Recruiting
Hormonal Contraception
0 Actively Recruiting
Mild to Moderate Acne
0 Actively Recruiting
Menopausal Osteoporosis
0 Actively Recruiting
Menopause
0 Actively Recruiting
Acne Vulgaris
0 Actively Recruiting

Ortho-Cept Reviews: What are patients saying about Ortho-Cept?

5Patient Review
8/15/2008
Ortho-Cept for Birth Control
I've been on this medication for 16 years now and it's been great! I've had no problems with it, except for some recent spotting. My doctor just switched me to something else. This is the only pill that hasn't made me sick to my stomach.
5Patient Review
7/6/2016
Ortho-Cept for Acne
I was very pleased with this medication, though the first few weeks were a bit difficult. I experienced some nausea and cramping, but nothing too severe. My acne cleared up completely, which was a huge plus, and I didn't experience any negative side effects after several months of use.
4.3Patient Review
1/9/2013
Ortho-Cept for Birth Control
I've been using this medication for four months with great results, but I've noticed a change in my period recently. Where before it was very heavy and would last a week, now it's light and only lasts a couple days. Cramp pain is gone and have had no side effects yet, I also lost a few pounds which was great!
4.3Patient Review
2/27/2012
Ortho-Cept for Birth Control
I'm really happy with this birth control. I had a few issues the first week, but no side effects that I've experienced so far.
4Patient Review
3/24/2009
Ortho-Cept for Birth Control
I'm pleased with the results of this medication, but I am curious about whether or not it will interfere with my menstrual cycle.
3.7Patient Review
4/29/2014
Ortho-Cept for Birth Control
I found this treatment to be very ineffective. Not only did it do nothing to help my depression, but it also made me gain weight and lose interest in sex. The only positive effect I experienced was that it lightened the texture of my facial and body hair.
3.7Patient Review
1/18/2009
Ortho-Cept for Birth Control
While taking this medication, my blood pressure rose to an unhealthy level and I had to discontinue use.
3.3Patient Review
11/3/2009
Ortho-Cept for Birth Control
I had some negative side effects when I first started taking this medication, including dizziness and migraines. Those went away for a little while but have since returned. I've also been experiencing stomach pain, weight gain, and loss of libido. I'm going to talk to my doctor about it tomorrow and see what they say.
3Patient Review
11/17/2007
Ortho-Cept for Disease of Ovaries with Cysts
I had good results with this medication in terms of my initial symptoms, but then I began having rare side effects like severe migraines and stomach pains. Additionally, I started feeling depressed and having suicidal thoughts. So, obviously, I stopped taking the medication and haven't gone back since. When I told my doctor about what happened, they said they were surprised but not shocked to hear it; apparently, this is a relatively common side effect of the drug.
1.7Patient Review
2/16/2010
Ortho-Cept for Birth Control
I was really disappointed with this product. I spotted for an entire month within the first month of use, and then experienced a significant dip in my mood and motivation levels. Sex was no longer enjoyable.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about ortho-cept

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Why was Ortho-Cept discontinued?

"Ortho-Cept, a birth control pill, is being recalled due to the potential for it to have low potency."

Answered by AI

Is Ortho-Cept discontinued?

"The Ortho-Cept brand name has been stopped in the U.S. If cheaper copies of this product have been approved by the FDA, there might be cheaper equivalents available."

Answered by AI

What is Ortho-Cept used for?

"This medication is a combination of two hormones, progestin and estrogen, which are used to prevent pregnancy. In addition to preventing pregnancy, birth control pills may also make your periods more regular, decrease blood loss and pain during periods, decrease your risk of ovarian cysts, and treat acne."

Answered by AI

What is the equivalent of Ortho-Cept?

"The FDA has declared that the following brands of oral contraceptives are safe and effective for emergency contraception: Ovral ® (1 dose is 2 white pills), Alesse ® (1 dose is 5 pink pills), Nordette ® or Levlen ® (1 dose is 4 yellow pills)."

Answered by AI

Clinical Trials for Ortho-Cept

Have you considered Ortho-Cept clinical trials? We made a collection of clinical trials featuring Ortho-Cept, we think they might fit your search criteria.
Have you considered Ortho-Cept clinical trials? We made a collection of clinical trials featuring Ortho-Cept, we think they might fit your search criteria.
Have you considered Ortho-Cept clinical trials? We made a collection of clinical trials featuring Ortho-Cept, we think they might fit your search criteria.
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