Norethindrone And Ethinyl Estradiol

Endometriosis, Low Testosterone, Osteoporosis + 16 more
Treatment
20 Active Studies for Norethindrone And Ethinyl Estradiol

What is Norethindrone And Ethinyl Estradiol

NorethisteroneThe Generic name of this drug
Treatment SummaryNorethisterone (also known as norethindrone) is a hormone medication used to treat menstrual irregularity and endometriosis. It is a synthetic version of the hormone progesterone and is more powerful than the natural hormone. Norethisterone is also used in combination with other hormones for contraception and hormone replacement therapy. It was first developed in 1951 and approved for use as a contraceptive in 1962.
Neconis the brand name
image of different drug pills on a surface
Norethindrone And Ethinyl Estradiol Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Necon
Norethisterone
1967
347

Effectiveness

How Norethindrone And Ethinyl Estradiol Affects PatientsNorethisterone is a type of medicine taken by mouth that is used for birth control or to treat other hormone-related conditions. It is a much stronger version of the hormone progesterone, and works by changing the cervical and endometrial function, as well as blocking hormones that are linked to ovulation. Taking this medicine may slightly increase the risk of developing breast cancer, so patients should be aware of this risk and do regular self-examinations to check for any lumps or masses.
How Norethindrone And Ethinyl Estradiol works in the bodyNorethisterone works by changing the environment of the reproductive tract to make it harder for sperm to move around, and making the endometrium inhospitable for implantation. It also suppresses the release of hormones that help with ovulation, preventing eggs from being released. When used in hormone replacement therapy, it suppresses the growth of the endometrium, reducing the risk of cancer. Finally, it has a low affinity for other hormone receptors, but can still cause some adverse effects like acne and changes in lipids.

When to interrupt dosage

The measure of Norethindrone And Ethinyl Estradiol is dependent on the determined illness, including Atrophic, Fracture and Hormone Replacement Therapy. The amount of dosage is contingent upon the method of administration (e.g. Oral or Tablet) as specified in the table below.
Condition
Dosage
Administration
Therapeutic procedure
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Low Testosterone
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Primary Ovarian Insufficiency
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Osteoporosis
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
hypoestrogenism
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Endometriosis
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Vasomotor System
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Estrogen Deprivation Symptoms
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Hormone Replacement Therapy
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Hormonal Contraception
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Menopause
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Birth Control
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
female castration
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Endometriosis
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Hot flashes
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Fracture
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Osteoporosis, Postmenopausal
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Atrophic
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Oral Contraceptives
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical

Warnings

Norethindrone And Ethinyl Estradiol has eight counterindications. It should not be administered if any of the conditions in the subsequent table are present.Norethindrone And Ethinyl Estradiol Contraindications
Condition
Risk Level
Notes
Liver Diseases
Do Not Combine
Thrombophilia
Do Not Combine
Vaginal Hemorrhage
Do Not Combine
Malignant Neoplasms
Do Not Combine
Benign hepatic neoplasm
Do Not Combine
Breast Cancer
Do Not Combine
Thromboembolism
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Norethisterone may interact with Pulse Frequency
There are 20 known major drug interactions with Norethindrone And Ethinyl Estradiol.
Common Norethindrone And Ethinyl Estradiol Drug Interactions
Drug Name
Risk Level
Description
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Norethisterone.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Norethisterone.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Norethisterone.
Clomipramine
Major
The metabolism of Clomipramine can be increased when combined with Norethisterone.
Copanlisib
Major
The metabolism of Copanlisib can be decreased when combined with Norethisterone.
Norethindrone And Ethinyl Estradiol Toxicity & Overdose RiskThe lowest toxic dose of oral contraceptives in mice is 6g/kg, and in women is 42mg/kg. No serious side effects have been reported after overdose, but nausea and/or vomiting are likely to occur.
image of a doctor in a lab doing drug, clinical research

Norethindrone And Ethinyl Estradiol Novel Uses: Which Conditions Have a Clinical Trial Featuring Norethindrone And Ethinyl Estradiol?

160 active studies are currently underway to examine the potential of Norethindrone And Ethinyl Estradiol in providing Birth Control, Atrophic Uterine Conditions and Low Testosterone Levels.
Condition
Clinical Trials
Trial Phases
Osteoporosis
34 Actively Recruiting
Not Applicable, Phase 2, Phase 4, Phase 1, Phase 3
Endometriosis
30 Actively Recruiting
Early Phase 1, Phase 2, Phase 3, Not Applicable, Phase 4
Birth Control
23 Actively Recruiting
Not Applicable, Phase 3, Phase 4, Early Phase 1
Estrogen Deprivation Symptoms
0 Actively Recruiting
female castration
0 Actively Recruiting
Endometriosis
3 Actively Recruiting
Phase 4, Not Applicable
Oral Contraceptives
0 Actively Recruiting
Osteoporosis, Postmenopausal
0 Actively Recruiting
Hot flashes
18 Actively Recruiting
Phase 1, Phase 4, Not Applicable, Early Phase 1, Phase 2, Phase 3
Low Testosterone
5 Actively Recruiting
Phase 4, Phase 2, Phase 1
Atrophic
3 Actively Recruiting
Phase 4, Not Applicable
Hormone Replacement Therapy
0 Actively Recruiting
Hormonal Contraception
0 Actively Recruiting
hypoestrogenism
2 Actively Recruiting
Phase 4
Fracture
0 Actively Recruiting
Vasomotor System
0 Actively Recruiting
Primary Ovarian Insufficiency
0 Actively Recruiting
Therapeutic procedure
0 Actively Recruiting
Menopause
0 Actively Recruiting

Norethindrone And Ethinyl Estradiol Reviews: What are patients saying about Norethindrone And Ethinyl Estradiol?

5Patient Review
8/10/2020
Norethindrone And Ethinyl Estradiol for Painful Periods
This medication has been wonderful for me. It's helped regulate my periods and made them much shorter and less painful. It's also an effective form of birth control. The only issue I had was some spotting when I first started taking the pills, but that resolved after a couple of months as my body adjusted to the hormones.
5Patient Review
3/15/2022
Norethindrone And Ethinyl Estradiol for Painful Periods
I was originally hesitant to try this medication, but I'm so glad I did. It's been incredibly effective in preventing ovarian cysts and hasn't had any negative side effects that I've noticed.
5Patient Review
8/10/2020
Norethindrone And Ethinyl Estradiol for Painful Periods
This medication has been great for both my heavy, painful periods and as a form of birth control. My periods are now only one or two days long, which is such a relief. The spotting I experienced in the first few months stopped once my body adjusted to the new hormones.
5Patient Review
3/15/2022
Norethindrone And Ethinyl Estradiol for Painful Periods
I was initially hesitant to try this medication because I had been doing so well with my IUD, but it turns out this is the best birth control pill I've ever been on. No weight changes or emotional symptoms that I could tell. I did have to switch OBGYNs though, which wasn't ideal.
5Patient Review
3/21/2022
Norethindrone And Ethinyl Estradiol for Premenstrual Disorder with a State of Unhappiness
I started taking this medication for bad premenstrual nausea and it has been really effective. I've had no nausea and it's also good at preventing pregnancy.
View All Reviews
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about norethindrone and ethinyl estradiol

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How effective is norethindrone and ethinyl estradiol?

"Other norethindrone/ethinyl estradiol pills have a success rate of more than 99% when used as directed."

Answered by AI

Does ethinyl estradiol stop your period?

"The birth control pill contains 2 hormones: levonorgestrel (a progestin) and ethinyl estradiol (an estrogen). Besides preventing pregnancy, birth control pills may also make your periods more regular, decrease blood loss and painful periods, decrease your risk of ovarian cysts, and treat acne."

Answered by AI

What is the brand name for norethindrone ethinyl estradiol?

"This is a description of the drug Loestrin, which is used to treat conditions like birth control and acne. Some of the possible side effects of this drug include weight gain, headaches, and breast tenderness."

Answered by AI

What kind of birth control is norethindrone acetate and ethinyl estradiol?

"Norethindrone acetate and ethinyl estradiol is an oral contraceptive that combines two types of female hormones, an estrogen and a progestin. These products prevent ovulation and pregnancy."

Answered by AI

Clinical Trials for Norethindrone And Ethinyl Estradiol

Have you considered Norethindrone And Ethinyl Estradiol clinical trials? We made a collection of clinical trials featuring Norethindrone And Ethinyl Estradiol, we think they might fit your search criteria.
Have you considered Norethindrone And Ethinyl Estradiol clinical trials? We made a collection of clinical trials featuring Norethindrone And Ethinyl Estradiol, we think they might fit your search criteria.
Have you considered Norethindrone And Ethinyl Estradiol clinical trials? We made a collection of clinical trials featuring Norethindrone And Ethinyl Estradiol, we think they might fit your search criteria.
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