Mediterranean Diet for Sickle Cell Disease
(MedSCP Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to determine if switching to a Mediterranean Diet can reduce pain for people with Sickle Cell Disease. Researchers will compare pain levels between participants eating Mediterranean foods and those maintaining their usual diets. Individuals with Sickle Cell Disease who experience chronic pain most days of the week may be suitable for this study. Participants in the Mediterranean diet group will receive ready-made meals. As an unphased trial, this study offers a unique opportunity to explore new dietary approaches to managing chronic pain.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What prior data suggests that the Mediterranean Diet is safe for individuals with Sickle Cell Disease?
Research has shown that the Mediterranean Diet is generally safe. This diet includes plenty of fruits, vegetables, whole grains, and healthy fats like olive oil. It is not a new drug or supplement, so it is considered safe because many people already eat this way.
Although specific safety data from clinical trials for this diet in people with Sickle Cell Disease is lacking, its foods are commonly consumed and are part of healthy diets worldwide. Since this diet is not a medication, it does not have the usual side effects that new drugs might have. Instead, it offers a balanced and nutritious way of eating, often recommended for good health.
In summary, the Mediterranean Diet is safe for most people and could help manage Sickle Cell Disease symptoms by improving nutrition.12345Why are researchers excited about this trial?
The Mediterranean Diet is unique for treating sickle cell disease because it emphasizes whole foods like fruits, vegetables, fish, and healthy fats, which are not typically part of the standard treatment approach. Unlike conventional treatments that often involve medications like hydroxyurea or blood transfusions, the Mediterranean Diet may improve overall health and reduce inflammation naturally. Researchers are excited about this approach because it could offer a non-drug strategy to support patients' well-being and potentially enhance their quality of life.
What evidence suggests that the Mediterranean Diet might be an effective treatment for Sickle Cell Disease?
This trial will compare the effects of the Mediterranean Diet with a Usual Diet for individuals with Sickle Cell Disease. Research suggests that the Mediterranean Diet might help reduce pain for people with this condition. While specific studies have not yet directly linked this diet to pain relief in Sickle Cell Disease, it is known for reducing inflammation. The diet emphasizes fruits, vegetables, whole grains, and healthy fats, which can lower inflammation in the body. Less inflammation might lead to fewer pain episodes, common in Sickle Cell Disease. Early findings in other health conditions show that dietary changes can improve overall health, potentially benefiting those with Sickle Cell Disease.14678
Are You a Good Fit for This Trial?
This trial is for individuals with Sickle Cell Disease who experience chronic pain on most days and do not currently follow a Mediterranean diet. Participants must be able to communicate effectively in English.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants follow either a Mediterranean Diet or their usual diet for 4 weeks
Crossover
Participants switch diets and follow the alternate diet for another 4 weeks
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Mediterranean Diet
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Illinois at Chicago
Lead Sponsor