Nexiclon Xr

Hot Flashes, Smoke, clonidine suppression test + 15 more
Treatment
20 Active Studies for Nexiclon Xr

What is Nexiclon Xr

ClonidineThe Generic name of this drug
Treatment SummaryClonidine is a drug used to treat high blood pressure, severe pain, and Attention Deficit Hyperactivity Disorder (ADHD). It works by targeting alpha-2 adrenoceptors in the body. Clonidine was approved by the FDA in 1974 and is available under the brand name Catapres.
Catapresis the brand name
image of different drug pills on a surface
Nexiclon Xr Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Catapres
Clonidine
1974
447

Effectiveness

How Nexiclon Xr Affects PatientsClonidine works by activating certain receptors in the body that help to lower blood pressure, cause drowsiness, and make nerves less sensitive. It usually needs to be taken twice a day and the usual dose is between 0.1mg and 2.4mg per day.
How Nexiclon Xr works in the bodyClonidine is a type of drug that works on the alpha-2 adrenoceptor, a kind of protein in your body. When clonidine binds to this receptor, it causes changes in the cell that stop it from functioning as normal. This leads to a decrease in nerve activity, which can reduce pain signals and create a hypnotic effect. It can also affect the way your body regulates blood pressure.

When to interrupt dosage

The advised dosage of Nexiclon Xr is contingent upon the diagnosed disorder, including methadone, diabetic diarrhea and Hypertensive disease. The measure of dosage also depends upon the technique of delivery (e.g. Oral or Tablet) featured in the table hereunder.
Condition
Dosage
Administration
diabetic diarrhea
, 0.1 mg, 0.2 mg, 0.3 mg, 0.5 mg/mL, 0.1 mg/mL, 0.01 mg/hour, 0.02 mg/hour, 0.03 mg/hour, 0.09 mg/mL, 0.17 mg, 0.26 mg, 0.025 mg, 0.15 mg, 25.0 mg
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Transdermal, Patch, Patch - Transdermal, Patch, extended release, Patch, extended release - Transdermal, For suspension, extended release, For suspension, extended release - Oral, Epidural, Injection, solution - Epidural, Kit, Kit - Oral, Suspension, extended release, Suspension, extended release - Oral
clonidine suppression test
, 0.1 mg, 0.2 mg, 0.3 mg, 0.5 mg/mL, 0.1 mg/mL, 0.01 mg/hour, 0.02 mg/hour, 0.03 mg/hour, 0.09 mg/mL, 0.17 mg, 0.26 mg, 0.025 mg, 0.15 mg, 25.0 mg
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Transdermal, Patch, Patch - Transdermal, Patch, extended release, Patch, extended release - Transdermal, For suspension, extended release, For suspension, extended release - Oral, Epidural, Injection, solution - Epidural, Kit, Kit - Oral, Suspension, extended release, Suspension, extended release - Oral
Defiant Disorder, Oppositional
, 0.1 mg, 0.2 mg, 0.3 mg, 0.5 mg/mL, 0.1 mg/mL, 0.01 mg/hour, 0.02 mg/hour, 0.03 mg/hour, 0.09 mg/mL, 0.17 mg, 0.26 mg, 0.025 mg, 0.15 mg, 25.0 mg
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Transdermal, Patch, Patch - Transdermal, Patch, extended release, Patch, extended release - Transdermal, For suspension, extended release, For suspension, extended release - Oral, Epidural, Injection, solution - Epidural, Kit, Kit - Oral, Suspension, extended release, Suspension, extended release - Oral
Smoke
, 0.1 mg, 0.2 mg, 0.3 mg, 0.5 mg/mL, 0.1 mg/mL, 0.01 mg/hour, 0.02 mg/hour, 0.03 mg/hour, 0.09 mg/mL, 0.17 mg, 0.26 mg, 0.025 mg, 0.15 mg, 25.0 mg
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Transdermal, Patch, Patch - Transdermal, Patch, extended release, Patch, extended release - Transdermal, For suspension, extended release, For suspension, extended release - Oral, Epidural, Injection, solution - Epidural, Kit, Kit - Oral, Suspension, extended release, Suspension, extended release - Oral
Smoking Cessation
, 0.1 mg, 0.2 mg, 0.3 mg, 0.5 mg/mL, 0.1 mg/mL, 0.01 mg/hour, 0.02 mg/hour, 0.03 mg/hour, 0.09 mg/mL, 0.17 mg, 0.26 mg, 0.025 mg, 0.15 mg, 25.0 mg
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Transdermal, Patch, Patch - Transdermal, Patch, extended release, Patch, extended release - Transdermal, For suspension, extended release, For suspension, extended release - Oral, Epidural, Injection, solution - Epidural, Kit, Kit - Oral, Suspension, extended release, Suspension, extended release - Oral
Hypertensive disease
, 0.1 mg, 0.2 mg, 0.3 mg, 0.5 mg/mL, 0.1 mg/mL, 0.01 mg/hour, 0.02 mg/hour, 0.03 mg/hour, 0.09 mg/mL, 0.17 mg, 0.26 mg, 0.025 mg, 0.15 mg, 25.0 mg
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Transdermal, Patch, Patch - Transdermal, Patch, extended release, Patch, extended release - Transdermal, For suspension, extended release, For suspension, extended release - Oral, Epidural, Injection, solution - Epidural, Kit, Kit - Oral, Suspension, extended release, Suspension, extended release - Oral
Disease
, 0.1 mg, 0.2 mg, 0.3 mg, 0.5 mg/mL, 0.1 mg/mL, 0.01 mg/hour, 0.02 mg/hour, 0.03 mg/hour, 0.09 mg/mL, 0.17 mg, 0.26 mg, 0.025 mg, 0.15 mg, 25.0 mg
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Transdermal, Patch, Patch - Transdermal, Patch, extended release, Patch, extended release - Transdermal, For suspension, extended release, For suspension, extended release - Oral, Epidural, Injection, solution - Epidural, Kit, Kit - Oral, Suspension, extended release, Suspension, extended release - Oral
Cancer Pain
, 0.1 mg, 0.2 mg, 0.3 mg, 0.5 mg/mL, 0.1 mg/mL, 0.01 mg/hour, 0.02 mg/hour, 0.03 mg/hour, 0.09 mg/mL, 0.17 mg, 0.26 mg, 0.025 mg, 0.15 mg, 25.0 mg
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Transdermal, Patch, Patch - Transdermal, Patch, extended release, Patch, extended release - Transdermal, For suspension, extended release, For suspension, extended release - Oral, Epidural, Injection, solution - Epidural, Kit, Kit - Oral, Suspension, extended release, Suspension, extended release - Oral
Hot Flashes
, 0.1 mg, 0.2 mg, 0.3 mg, 0.5 mg/mL, 0.1 mg/mL, 0.01 mg/hour, 0.02 mg/hour, 0.03 mg/hour, 0.09 mg/mL, 0.17 mg, 0.26 mg, 0.025 mg, 0.15 mg, 25.0 mg
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Transdermal, Patch, Patch - Transdermal, Patch, extended release, Patch, extended release - Transdermal, For suspension, extended release, For suspension, extended release - Oral, Epidural, Injection, solution - Epidural, Kit, Kit - Oral, Suspension, extended release, Suspension, extended release - Oral
Attention Deficit Hyperactivity Disorder
, 0.1 mg, 0.2 mg, 0.3 mg, 0.5 mg/mL, 0.1 mg/mL, 0.01 mg/hour, 0.02 mg/hour, 0.03 mg/hour, 0.09 mg/mL, 0.17 mg, 0.26 mg, 0.025 mg, 0.15 mg, 25.0 mg
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Transdermal, Patch, Patch - Transdermal, Patch, extended release, Patch, extended release - Transdermal, For suspension, extended release, For suspension, extended release - Oral, Epidural, Injection, solution - Epidural, Kit, Kit - Oral, Suspension, extended release, Suspension, extended release - Oral
Hot flashes
, 0.1 mg, 0.2 mg, 0.3 mg, 0.5 mg/mL, 0.1 mg/mL, 0.01 mg/hour, 0.02 mg/hour, 0.03 mg/hour, 0.09 mg/mL, 0.17 mg, 0.26 mg, 0.025 mg, 0.15 mg, 25.0 mg
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Transdermal, Patch, Patch - Transdermal, Patch, extended release, Patch, extended release - Transdermal, For suspension, extended release, For suspension, extended release - Oral, Epidural, Injection, solution - Epidural, Kit, Kit - Oral, Suspension, extended release, Suspension, extended release - Oral
Postherpetic Neuralgia
, 0.1 mg, 0.2 mg, 0.3 mg, 0.5 mg/mL, 0.1 mg/mL, 0.01 mg/hour, 0.02 mg/hour, 0.03 mg/hour, 0.09 mg/mL, 0.17 mg, 0.26 mg, 0.025 mg, 0.15 mg, 25.0 mg
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Transdermal, Patch, Patch - Transdermal, Patch, extended release, Patch, extended release - Transdermal, For suspension, extended release, For suspension, extended release - Oral, Epidural, Injection, solution - Epidural, Kit, Kit - Oral, Suspension, extended release, Suspension, extended release - Oral
Gilles de la Tourette's Syndrome
, 0.1 mg, 0.2 mg, 0.3 mg, 0.5 mg/mL, 0.1 mg/mL, 0.01 mg/hour, 0.02 mg/hour, 0.03 mg/hour, 0.09 mg/mL, 0.17 mg, 0.26 mg, 0.025 mg, 0.15 mg, 25.0 mg
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Transdermal, Patch, Patch - Transdermal, Patch, extended release, Patch, extended release - Transdermal, For suspension, extended release, For suspension, extended release - Oral, Epidural, Injection, solution - Epidural, Kit, Kit - Oral, Suspension, extended release, Suspension, extended release - Oral
clozapine
, 0.1 mg, 0.2 mg, 0.3 mg, 0.5 mg/mL, 0.1 mg/mL, 0.01 mg/hour, 0.02 mg/hour, 0.03 mg/hour, 0.09 mg/mL, 0.17 mg, 0.26 mg, 0.025 mg, 0.15 mg, 25.0 mg
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Transdermal, Patch, Patch - Transdermal, Patch, extended release, Patch, extended release - Transdermal, For suspension, extended release, For suspension, extended release - Oral, Epidural, Injection, solution - Epidural, Kit, Kit - Oral, Suspension, extended release, Suspension, extended release - Oral
Human Growth Hormone Deficiency
, 0.1 mg, 0.2 mg, 0.3 mg, 0.5 mg/mL, 0.1 mg/mL, 0.01 mg/hour, 0.02 mg/hour, 0.03 mg/hour, 0.09 mg/mL, 0.17 mg, 0.26 mg, 0.025 mg, 0.15 mg, 25.0 mg
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Transdermal, Patch, Patch - Transdermal, Patch, extended release, Patch, extended release - Transdermal, For suspension, extended release, For suspension, extended release - Oral, Epidural, Injection, solution - Epidural, Kit, Kit - Oral, Suspension, extended release, Suspension, extended release - Oral
methadone
, 0.1 mg, 0.2 mg, 0.3 mg, 0.5 mg/mL, 0.1 mg/mL, 0.01 mg/hour, 0.02 mg/hour, 0.03 mg/hour, 0.09 mg/mL, 0.17 mg, 0.26 mg, 0.025 mg, 0.15 mg, 25.0 mg
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Transdermal, Patch, Patch - Transdermal, Patch, extended release, Patch, extended release - Transdermal, For suspension, extended release, For suspension, extended release - Oral, Epidural, Injection, solution - Epidural, Kit, Kit - Oral, Suspension, extended release, Suspension, extended release - Oral
growth hormone stimulation test
, 0.1 mg, 0.2 mg, 0.3 mg, 0.5 mg/mL, 0.1 mg/mL, 0.01 mg/hour, 0.02 mg/hour, 0.03 mg/hour, 0.09 mg/mL, 0.17 mg, 0.26 mg, 0.025 mg, 0.15 mg, 25.0 mg
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Transdermal, Patch, Patch - Transdermal, Patch, extended release, Patch, extended release - Transdermal, For suspension, extended release, For suspension, extended release - Oral, Epidural, Injection, solution - Epidural, Kit, Kit - Oral, Suspension, extended release, Suspension, extended release - Oral
Pheochromocytomas
, 0.1 mg, 0.2 mg, 0.3 mg, 0.5 mg/mL, 0.1 mg/mL, 0.01 mg/hour, 0.02 mg/hour, 0.03 mg/hour, 0.09 mg/mL, 0.17 mg, 0.26 mg, 0.025 mg, 0.15 mg, 25.0 mg
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Transdermal, Patch, Patch - Transdermal, Patch, extended release, Patch, extended release - Transdermal, For suspension, extended release, For suspension, extended release - Oral, Epidural, Injection, solution - Epidural, Kit, Kit - Oral, Suspension, extended release, Suspension, extended release - Oral

Warnings

Nexiclon Xr has five contraindications, so it should not be employed when afflicted with any of the conditions noted in the table below.Nexiclon Xr Contraindications
Condition
Risk Level
Notes
Pulse Frequency
Do Not Combine
administration above the C4 dermatome
Do Not Combine
Communicable Diseases
Do Not Combine
bleeding diathesis
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Clonidine may interact with Pulse Frequency
There are 20 known major drug interactions with Nexiclon Xr.
Common Nexiclon Xr Drug Interactions
Drug Name
Risk Level
Description
1,2-Benzodiazepine
Major
The risk or severity of sedation can be increased when Clonidine is combined with 1,2-Benzodiazepine.
2,5-Dimethoxy-4-ethylthioamphetamine
Major
The risk or severity of sedation can be increased when Clonidine is combined with 2,5-Dimethoxy-4-ethylthioamphetamine.
4-Bromo-2,5-dimethoxyamphetamine
Major
The risk or severity of sedation can be increased when Clonidine is combined with 4-Bromo-2,5-dimethoxyamphetamine.
4-Methoxyamphetamine
Major
The risk or severity of sedation can be increased when Clonidine is combined with 4-Methoxyamphetamine.
5-methoxy-N,N-dimethyltryptamine
Major
The risk or severity of sedation can be increased when Clonidine is combined with 5-methoxy-N,N-dimethyltryptamine.
Nexiclon Xr Toxicity & Overdose RiskThe lowest toxic dose of this drug in rats is 126 mg/kg. In children, women, and men, the lowest toxic dose is 70µg/kg, 126µg/kg, and 69µg/kg respectively. An overdose of this drug can cause high or low blood pressure, slow heart rate, difficulty breathing, low body temperature, drowsiness, decreased reflexes, weakness, irritability, and constricted pupils. Severe overdoses can also cause heart rhythm problems, apnea, coma, and seizures. Vomiting is not recommended due to CNS depression, but a gastric lavage
image of a doctor in a lab doing drug, clinical research

Nexiclon Xr Novel Uses: Which Conditions Have a Clinical Trial Featuring Nexiclon Xr?

231 active trials are in progress to assess the potential of Nexiclon Xr for Smoking Cessation, Menopausal symptom relief and severe Cancer pain mitigation.
Condition
Clinical Trials
Trial Phases
Cancer Pain
0 Actively Recruiting
methadone
0 Actively Recruiting
Postherpetic Neuralgia
0 Actively Recruiting
Defiant Disorder, Oppositional
5 Actively Recruiting
Not Applicable
growth hormone stimulation test
0 Actively Recruiting
Pheochromocytomas
0 Actively Recruiting
Smoke
0 Actively Recruiting
Disease
9 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 1
Attention Deficit Hyperactivity Disorder
75 Actively Recruiting
Phase 4, Not Applicable, Phase 1, Phase 2, Phase 3, Early Phase 1
Smoking Cessation
101 Actively Recruiting
Early Phase 1, Not Applicable, Phase 2, Phase 4, Phase 1, Phase 3
diabetic diarrhea
0 Actively Recruiting
Gilles de la Tourette's Syndrome
0 Actively Recruiting
clozapine
0 Actively Recruiting
Human Growth Hormone Deficiency
7 Actively Recruiting
Phase 3, Phase 2, Phase 4
Hypertensive disease
18 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3
Hot flashes
22 Actively Recruiting
Phase 2, Not Applicable, Phase 1, Phase 4, Early Phase 1
Hot Flashes
15 Actively Recruiting
Phase 3, Not Applicable, Phase 2, Phase 1
clonidine suppression test
0 Actively Recruiting

Nexiclon Xr Reviews: What are patients saying about Nexiclon Xr?

1Patient Review
1/18/2012
Nexiclon Xr for Symptoms from Stopping Treatment with Opioid Drugs
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about nexiclon xr

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the drug clonidine used for?

"This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure.

Clonidine is used to treat high blood pressure by decreasing the amount of work the heart and arteries have to do. If left untreated, high blood pressure can damage the blood vessels in the brain, heart, and kidneys, which can lead to a stroke, heart failure, or kidney failure."

Answered by AI

What happens if you take too much clonidine?

"If you take too much clonidine, your blood pressure or heart rate could drop dangerously low, you could become deeply sedated, and you might have trouble breathing normally."

Answered by AI

Can you stop clonidine abruptly?

"Do not interrupt or stop taking this medicine without first checking with your doctor. Your doctor may want you to gradually reduce the amount you are taking before stopping it completely. Your blood pressure may become worse when the medicine is stopped suddenly, which can cause serious side effects."

Answered by AI

Clinical Trials for Nexiclon Xr

Have you considered Nexiclon Xr clinical trials? We made a collection of clinical trials featuring Nexiclon Xr, we think they might fit your search criteria.
Have you considered Nexiclon Xr clinical trials? We made a collection of clinical trials featuring Nexiclon Xr, we think they might fit your search criteria.
Have you considered Nexiclon Xr clinical trials? We made a collection of clinical trials featuring Nexiclon Xr, we think they might fit your search criteria.