Myfortic

Steroid therapy

Treatment

2 FDA approvals

0 Active Studies for Myfortic

What is Myfortic

Mycophenolic acid

The Generic name of this drug

Treatment Summary

Mycophenolic acid is a drug used to suppress the immune system and prevent the growth of cells. It is often prescribed together with calcineurin inhibitor (ciclosporin or tacrolimus) and prednisolone. It is also used in research for selecting animal cells that contain a certain gene found in E. coli bacteria.

Myfortic

is the brand name

Myfortic Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Myfortic

Mycophenolic acid

2004

41

Approved as Treatment by the FDA

Mycophenolic acid, also known as Myfortic, is approved by the FDA for 2 uses which include Kidney Transplant Rejection and Steroid therapy .

Kidney Transplant Rejection

Used to treat Kidney Transplant Rejection in combination with Cyclosporine

Steroid therapy

Used to treat Steroid therapy in combination with Cyclosporine

Effectiveness

How Myfortic Affects Patients

Mycophenolic acid is used to block the production of certain molecules in the body such as lymphocytes, which can help suppress DNA synthesis and cytokine production. Taking this drug can also put patients at a higher risk of developing infections, blood issues, gastrointestinal complications, and other malignancies. Mycophenolic acid should be avoided in patients with rare hereditary conditions and should not be taken with live attenuated vaccines or donated in blood or semen. The tablet form of the drug is designed to reduce the chances of developing upper gastrointestinal side effects.

How Myfortic works in the body

Mycophenolic acid stops T- and B-lymphocytes from reproducing. This is done by blocking the conversion of certain molecules, which interferes with the process of making new purines, which T- and B-lymphocytes rely on. Additionally, it stops antibodies from forming, and prevents glycoproteins in T- and B-lymphocytes from sticking to endothelial cells.

When to interrupt dosage

The degree of Myfortic is contingent upon the diagnosed condition. The amount of dosage fluctuates depending on the mode of delivery (e.g. Tablet, delayed release - Oral or Oral) featured in the table underneath.

Condition

Dosage

Administration

Steroid therapy

, 180.0 mg, 360.0 mg

, Tablet, delayed release, Tablet, delayed release - Oral, Oral

Warnings

Myfortic has two contraindications and its intake should be avoided when encountering any of the conditions provided in the table below.

Myfortic Contraindications

Condition

Risk Level

Notes

Severe Hypersensitivity Reactions

Do Not Combine

Mycophenolic Acid may interact with Pulse Frequency

Severe Hypersensitivity Reactions

Do Not Combine

Mycophenolic Acid may interact with Pulse Frequency

There are 20 known major drug interactions with Myfortic.

Common Myfortic Drug Interactions

Drug Name

Risk Level

Description

2-Methoxyethanol

Major

The risk or severity of adverse effects can be increased when Mycophenolic acid is combined with 2-Methoxyethanol.

9-(N-methyl-L-isoleucine)-cyclosporin A

Major

The risk or severity of adverse effects can be increased when Mycophenolic acid is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.

Abatacept

Major

The risk or severity of adverse effects can be increased when Mycophenolic acid is combined with Abatacept.

Abetimus

Major

The risk or severity of adverse effects can be increased when Mycophenolic acid is combined with Abetimus.

Acteoside

Major

The risk or severity of adverse effects can be increased when Mycophenolic acid is combined with Acteoside.

Myfortic Toxicity & Overdose Risk

There have been cases of people taking too much mycophenolic acid, although not everyone experiences negative side effects. Some people have reported a weakened immune system, blood disorders, and abdominal pain, diarrhea, nausea, vomiting, and indigestion. Studies have shown that mycophenolic acid does not cause tumors in rats or mice. High doses of up to 18 mg/kg for males and 20 mg/kg for females had no effect on fertility. The toxic dose in rats is 352 mg/kg, and in mice is 1000 mg/kg.

image of a doctor in a lab doing drug, clinical research

Myfortic Novel Uses: Which Conditions Have a Clinical Trial Featuring Myfortic?

14 active investigations are presently examining the potential of Myfortic in Steroid Therapy.

Condition

Clinical Trials

Trial Phases

Steroid therapy

0 Actively Recruiting

Myfortic Reviews: What are patients saying about Myfortic?

5

Patient Review

11/25/2012

Myfortic for Prevent Kidney Transplant Rejection

I've been taking Myfortic for seven years and have had a few manageable side effects, like hand tremors and occasional dizziness.

5

Patient Review

5/3/2016

Myfortic for Prevent Kidney Transplant Rejection

I didn't have any big problems with this medication. At first I had a lot of tremors, but they went away after a while.

5

Patient Review

11/25/2012

Myfortic for Prevent Kidney Transplant Rejection

I've been on Myfortic for seven years now. I have a few manageable side effects, like hand tremors and occasional dizziness. The tremors are constant but not extreme, while the dizziness is rare.

5

Patient Review

5/1/2009

Myfortic for Prevent Kidney Transplant Rejection

I had a kidney transplant in 2007 and found that this treatment works best for me at lower doses. Higher dosages made me very nauseous, and even taking it with food didn't help much. The smaller pill size of the lower dosage is also easier to take, and the lower dosage allows for more flexibility if the doctor needs to adjust the medication.

5

Patient Review

5/3/2016

Myfortic for Prevent Kidney Transplant Rejection

I experienced some tremors when I started taking this medication, but it subsided after a short period of time.

5

Patient Review

5/1/2009

Myfortic for Prevent Kidney Transplant Rejection

I received a kidney transplant in June 2007. I found that higher dosages of this medication made me very nauseous, and taking it with food did not help much. Lower dosages (360mg) were much easier for me to handle. I also found the lower prescription dosage of 180mg easier to take; it's a smaller pill to swallow AND the lower dosage allows the doctor to adjust medications (up or down) more easily.

4.7

Patient Review

2/10/2012

Myfortic for Prevent Kidney Transplant Rejection

This provided me with much-needed relief from my joint pain.

4.7

Patient Review

9/15/2021

Myfortic for Prevent Kidney Transplant Rejection

Excellent results for my kidney/pancreas transplant. Only downside is that I have trouble sleeping now.

4.7

Patient Review

10/30/2008

Myfortic for Prevent Kidney Transplant Rejection

It's hard to say if this drug would be effective for someone who's had chronic renal failure after a transplant for more than 20 years.

4.7

Patient Review

2/10/2012

Myfortic for Prevent Kidney Transplant Rejection

This treatment provided me with much-needed relief from my joint pain.

4.7

Patient Review

9/15/2021

Myfortic for Prevent Kidney Transplant Rejection

This treatment has been incredibly effective for my kidney/pancreas transplant. I haven't had any issues with my chemistry labs, which is great. The only downside is that it gives me insomnia.

4.7

Patient Review

10/30/2008

Myfortic for Prevent Kidney Transplant Rejection

4.7

Patient Review

10/30/2008

Myfortic for Prevent Kidney Transplant Rejection

4.7

Patient Review

10/30/2008

Myfortic for Prevent Kidney Transplant Rejection

I am not sure if this drug is effective for those who have had chronic renal failure for more than 20 years after a transplant.

4.3

Patient Review

3/14/2014

Myfortic for Prevent Kidney Transplant Rejection

I started taking Myfortic before my second transplant three years ago. I had previously taken celcept and had an adverse reaction to it after taking it for 7 Years. Myfortic has been a complete game-changer for me and made all the difference in my day to day life.I have no real systoms, sometimes headache, but all in all can't complain.

4.3

Patient Review

3/14/2014

Myfortic for Prevent Kidney Transplant Rejection

Myfortic has been a life-saver for me. I started taking it before my second transplant three years ago and it made all the difference in how I felt day-to-day. Celcept, by comparison, gave me headaches after only seven years; Myfortic has been much better for me overall.

4.3

Patient Review

7/18/2009

Myfortic for Prevent Kidney Transplant Rejection

The side effects have been a bit of a nuisance.

4.3

Patient Review

7/18/2009

Myfortic for Prevent Kidney Transplant Rejection

The side effects of this treatment have been a bit annoying.

4

Patient Review

6/11/2009

Myfortic for Prevent Kidney Transplant Rejection

I had a kidney transplant two years ago and, touch wood, have had no complications since. I'm also on 7.5 mg of prednisone.

4

Patient Review

6/11/2009

Myfortic for Prevent Kidney Transplant Rejection

I had a kidney transplant two years ago and have been taking 7.5 mg of prednisone since. So far, I haven't experienced any problems.

4

Patient Review

9/8/2008

Myfortic for Prevent Kidney Transplant Rejection

4

Patient Review

9/8/2008

Myfortic for Prevent Kidney Transplant Rejection

3

Patient Review

7/5/2011

Myfortic for Prevent Kidney Transplant Rejection

I take this drug to help with renal failure. I have had large amounts of protein in my urine, and I am also a Lupus patient. I'm still not quite sure what it's doing for me, but I have been on Cellcept and it is too harsh. Myfortic is also tough to tolerate, but I manage. I take 2 pills per day...900mg daily. The side effects are tough - diarrhea and loss of appetite are the main ones. As a result,I've lost weight.

3

Patient Review

9/4/2014

Myfortic for Prevent Kidney Transplant Rejection

I've had a lot of experience with transplants, and this medicine didn't work as well for me as other treatments I've tried.

3

Patient Review

7/5/2011

Myfortic for Prevent Kidney Transplant Rejection

I have renal failure and lupus, so my doctor put me on this medication. I'm not sure if it's helping or not, but I take 900mg per day. The biggest downside for me is the diarrhea and loss of appetite; I've lost weight since starting this treatment.

3

Patient Review

9/4/2014

Myfortic for Prevent Kidney Transplant Rejection

Since this is my second transplant, I found that different medications worked better for me than Myfortic
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about myfortic

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Myfortic an immunosuppressant?

"Myfortic is an immunosuppressive agent that is used to prevent the body from rejecting a kidney transplant. This medication works by weaken the immune system so that it does not attack the transplanted kidney."

Answered by AI

What are side effects of Myfortic?

"The following side effects may occur: constipation, nausea, headache, diarrhea, vomiting, stomach upset, gas, tremor, dizziness, drowsiness, or difficulty sleeping. If you experience any of these effects, tell your doctor or pharmacist."

Answered by AI

What is the drug Myfortic used for?

"Myfortic is for people who have had a kidney transplant to prevent the body from rejecting the new kidney, or for those who have inflammatory kidney disease associated with a chronic autoimmune disorder known as systemic lupus erythematosis."

Answered by AI

What is the difference between Myfortic and mycophenolate?

"Myfortic is a more advanced form of mycophenolate sodium that is enteric coated. This coating prevents the drug from being released in the stomach. instead, it is only released in the small intestine when the pH is high."

Answered by AI