Myfortic

Steroid therapy
Treatment
2 FDA approvals
0 Active Studies for Myfortic

What is Myfortic

Mycophenolic acidThe Generic name of this drug
Treatment SummaryMycophenolic acid is a drug used to suppress the immune system and prevent the growth of cells. It is often prescribed together with calcineurin inhibitor (ciclosporin or tacrolimus) and prednisolone. It is also used in research for selecting animal cells that contain a certain gene found in E. coli bacteria.
Myforticis the brand name
Myfortic Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Myfortic
Mycophenolic acid
2004
41

Approved as Treatment by the FDA

Mycophenolic acid, also known as Myfortic, is approved by the FDA for 2 uses which include Kidney Transplant Rejection and Steroid therapy .
Kidney Transplant Rejection
Used to treat Kidney Transplant Rejection in combination with Cyclosporine
Steroid therapy
Used to treat Steroid therapy in combination with Cyclosporine

Effectiveness

How Myfortic Affects PatientsMycophenolic acid is used to block the production of certain molecules in the body such as lymphocytes, which can help suppress DNA synthesis and cytokine production. Taking this drug can also put patients at a higher risk of developing infections, blood issues, gastrointestinal complications, and other malignancies. Mycophenolic acid should be avoided in patients with rare hereditary conditions and should not be taken with live attenuated vaccines or donated in blood or semen. The tablet form of the drug is designed to reduce the chances of developing upper gastrointestinal side effects.
How Myfortic works in the bodyMycophenolic acid stops T- and B-lymphocytes from reproducing. This is done by blocking the conversion of certain molecules, which interferes with the process of making new purines, which T- and B-lymphocytes rely on. Additionally, it stops antibodies from forming, and prevents glycoproteins in T- and B-lymphocytes from sticking to endothelial cells.

When to interrupt dosage

The degree of Myfortic is contingent upon the diagnosed condition. The amount of dosage fluctuates depending on the mode of delivery (e.g. Tablet, delayed release - Oral or Oral) featured in the table underneath.
Condition
Dosage
Administration
Steroid therapy
, 180.0 mg, 360.0 mg
, Oral, Tablet, delayed release, Tablet, delayed release - Oral

Warnings

Myfortic has two contraindications and its intake should be avoided when encountering any of the conditions provided in the table below.Myfortic Contraindications
Condition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Mycophenolic Acid may interact with Pulse Frequency
Severe Hypersensitivity Reactions
Do Not Combine
Mycophenolic Acid may interact with Pulse Frequency
There are 20 known major drug interactions with Myfortic.
Common Myfortic Drug Interactions
Drug Name
Risk Level
Description
2-Methoxyethanol
Major
The risk or severity of adverse effects can be increased when Mycophenolic acid is combined with 2-Methoxyethanol.
9-(N-methyl-L-isoleucine)-cyclosporin A
Major
The risk or severity of adverse effects can be increased when Mycophenolic acid is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Abatacept
Major
The risk or severity of adverse effects can be increased when Mycophenolic acid is combined with Abatacept.
Abetimus
Major
The risk or severity of adverse effects can be increased when Mycophenolic acid is combined with Abetimus.
Acteoside
Major
The risk or severity of adverse effects can be increased when Mycophenolic acid is combined with Acteoside.
Myfortic Toxicity & Overdose RiskThere have been cases of people taking too much mycophenolic acid, although not everyone experiences negative side effects. Some people have reported a weakened immune system, blood disorders, and abdominal pain, diarrhea, nausea, vomiting, and indigestion. Studies have shown that mycophenolic acid does not cause tumors in rats or mice. High doses of up to 18 mg/kg for males and 20 mg/kg for females had no effect on fertility. The toxic dose in rats is 352 mg/kg, and in mice is 1000 mg/kg.
image of a doctor in a lab doing drug, clinical research

Myfortic Novel Uses: Which Conditions Have a Clinical Trial Featuring Myfortic?

14 active investigations are presently examining the potential of Myfortic in Steroid Therapy.
Condition
Clinical Trials
Trial Phases
Steroid therapy
0 Actively Recruiting

Myfortic Reviews: What are patients saying about Myfortic?

5Patient Review
11/25/2012
Myfortic for Prevent Kidney Transplant Rejection
I've been taking Myfortic for seven years and have had a few manageable side effects, like hand tremors and occasional dizziness.
5Patient Review
5/3/2016
Myfortic for Prevent Kidney Transplant Rejection
I didn't have any big problems with this medication. At first I had a lot of tremors, but they went away after a while.
5Patient Review
11/25/2012
Myfortic for Prevent Kidney Transplant Rejection
I've been on Myfortic for seven years now. I have a few manageable side effects, like hand tremors and occasional dizziness. The tremors are constant but not extreme, while the dizziness is rare.
5Patient Review
5/1/2009
Myfortic for Prevent Kidney Transplant Rejection
I had a kidney transplant in 2007 and found that this treatment works best for me at lower doses. Higher dosages made me very nauseous, and even taking it with food didn't help much. The smaller pill size of the lower dosage is also easier to take, and the lower dosage allows for more flexibility if the doctor needs to adjust the medication.
5Patient Review
5/3/2016
Myfortic for Prevent Kidney Transplant Rejection
I experienced some tremors when I started taking this medication, but it subsided after a short period of time.
View All Reviews
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about myfortic

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Myfortic an immunosuppressant?

"Myfortic is an immunosuppressive agent that is used to prevent the body from rejecting a kidney transplant. This medication works by weaken the immune system so that it does not attack the transplanted kidney."

Answered by AI

What are side effects of Myfortic?

"The following side effects may occur: constipation, nausea, headache, diarrhea, vomiting, stomach upset, gas, tremor, dizziness, drowsiness, or difficulty sleeping. If you experience any of these effects, tell your doctor or pharmacist."

Answered by AI

What is the drug Myfortic used for?

"Myfortic is for people who have had a kidney transplant to prevent the body from rejecting the new kidney, or for those who have inflammatory kidney disease associated with a chronic autoimmune disorder known as systemic lupus erythematosis."

Answered by AI

What is the difference between Myfortic and mycophenolate?

"Myfortic is a more advanced form of mycophenolate sodium that is enteric coated. This coating prevents the drug from being released in the stomach. instead, it is only released in the small intestine when the pH is high."

Answered by AI
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