Medroxyprogesterone Acetate

Endometrial Hyperplasia, Endometriosis, Chronic Pain + 18 more
Treatment
4 FDA approvals
20 Active Studies for Medroxyprogesterone Acetate

What is Medroxyprogesterone Acetate

Medroxyprogesterone acetateThe Generic name of this drug
Treatment SummaryMedroxyprogesterone acetate (MPA) is a hormone-based medication that has an improved resistance to being broken down in the body. It is used to treat various conditions, such as abnormal menstrual bleeding, menopause symptoms, endometrial hyperplasia, endometriosis pain, and prevent pregnancy. It is also used to treat cancer and osteoporosis. MPA was approved by the FDA in 1959.
Medroxyprogesterone Acetateis the brand name
image of different drug pills on a surface
Medroxyprogesterone Acetate Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Medroxyprogesterone Acetate
Medroxyprogesterone acetate
1959
139

Approved as Treatment by the FDA

Medroxyprogesterone acetate, also known as Medroxyprogesterone Acetate, is approved by the FDA for 4 uses such as Atrophic and Hot flashes .
Atrophic
Used to treat Vulvo Vaginal Atrophy in combination with Conjugated estrogens
Hot flashes
Used to treat Menopause in combination with Conjugated estrogens
Vasomotor Symptoms Associated With Menopause
Used to treat Vasomotor Symptoms Associated With Menopause in combination with Conjugated estrogens
Postmenopausal Osteoporosis
Used to treat Postmenopausal Osteoporosis in combination with Conjugated estrogens

Effectiveness

How Medroxyprogesterone Acetate Affects PatientsMedroxyprogesterone acetate (MPA) works by stopping the production of certain hormones and reducing the presence of estrogen in the body. Depending on the form, it can last a long time in the body, from one day to several weeks. Doses of MPA range from 5mg taken orally daily to 1000mg as a weekly shot. Unfortunately, long-term use of MPA has been linked to reduced bone density, especially in adolescents, which can lead to increased risk of osteoporosis and fractures later in life.
How Medroxyprogesterone Acetate works in the bodyMedroxyprogesterone acetate (MPA) stops ovulation and thins the endometrium, making it an effective form of contraception. It also affects the endometrium by reducing the number of estrogen receptors and the amount of DNA it produces. MPA can also cause certain cancer cells to die and blocks GABA-A receptors.

When to interrupt dosage

The recommended dosage of Medroxyprogesterone Acetate is contingent upon the discerned condition, including Hormonal Contraception, Amenorrhea and Postmenopausal Osteoporosis. The amount of dosage is dependent on the administration technique (e.g. Tablet - Oral or Intramuscular) provided in the table below.
Condition
Dosage
Administration
hypoestrogenism
, 2.5 mg, 10.0 mg, 5.0 mg, 150.0 mg/mL, 400.0 mg/mL, 1.5 mg, 100.0 mg, 1040.0 mg/mL, 500.0 mg, 250.0 mg, 200.0 mg, 400.0 mg, 250.0 mg/mL, 50.0 mg/mL
, Oral, Tablet, Tablet - Oral, Intramuscular, Injection, suspension - Intramuscular, Injection, suspension, Tablet, sugar coated, Tablet, sugar coated - Oral, Suspension, Suspension - Intramuscular, Kit; Tablet, Kit; Tablet - Oral, Subcutaneous, Injection, suspension - Subcutaneous, Kit, Injection, suspension, extended release, Injection, suspension, extended release - Intramuscular, Injection, Injection - Intramuscular, Kit - Oral
Postmenopausal Osteoporosis
, 2.5 mg, 10.0 mg, 5.0 mg, 150.0 mg/mL, 400.0 mg/mL, 1.5 mg, 100.0 mg, 1040.0 mg/mL, 500.0 mg, 250.0 mg, 200.0 mg, 400.0 mg, 250.0 mg/mL, 50.0 mg/mL
, Oral, Tablet, Tablet - Oral, Intramuscular, Injection, suspension - Intramuscular, Injection, suspension, Tablet, sugar coated, Tablet, sugar coated - Oral, Suspension, Suspension - Intramuscular, Kit; Tablet, Kit; Tablet - Oral, Subcutaneous, Injection, suspension - Subcutaneous, Kit, Injection, suspension, extended release, Injection, suspension, extended release - Intramuscular, Injection, Injection - Intramuscular, Kit - Oral
Amenorrhea
, 2.5 mg, 10.0 mg, 5.0 mg, 150.0 mg/mL, 400.0 mg/mL, 1.5 mg, 100.0 mg, 1040.0 mg/mL, 500.0 mg, 250.0 mg, 200.0 mg, 400.0 mg, 250.0 mg/mL, 50.0 mg/mL
, Oral, Tablet, Tablet - Oral, Intramuscular, Injection, suspension - Intramuscular, Injection, suspension, Tablet, sugar coated, Tablet, sugar coated - Oral, Suspension, Suspension - Intramuscular, Kit; Tablet, Kit; Tablet - Oral, Subcutaneous, Injection, suspension - Subcutaneous, Kit, Injection, suspension, extended release, Injection, suspension, extended release - Intramuscular, Injection, Injection - Intramuscular, Kit - Oral
Osteoporosis
, 2.5 mg, 10.0 mg, 5.0 mg, 150.0 mg/mL, 400.0 mg/mL, 1.5 mg, 100.0 mg, 1040.0 mg/mL, 500.0 mg, 250.0 mg, 200.0 mg, 400.0 mg, 250.0 mg/mL, 50.0 mg/mL
, Oral, Tablet, Tablet - Oral, Intramuscular, Injection, suspension - Intramuscular, Injection, suspension, Tablet, sugar coated, Tablet, sugar coated - Oral, Suspension, Suspension - Intramuscular, Kit; Tablet, Kit; Tablet - Oral, Subcutaneous, Injection, suspension - Subcutaneous, Kit, Injection, suspension, extended release, Injection, suspension, extended release - Intramuscular, Injection, Injection - Intramuscular, Kit - Oral
Endometriosis
, 2.5 mg, 10.0 mg, 5.0 mg, 150.0 mg/mL, 400.0 mg/mL, 1.5 mg, 100.0 mg, 1040.0 mg/mL, 500.0 mg, 250.0 mg, 200.0 mg, 400.0 mg, 250.0 mg/mL, 50.0 mg/mL
, Oral, Tablet, Tablet - Oral, Intramuscular, Injection, suspension - Intramuscular, Injection, suspension, Tablet, sugar coated, Tablet, sugar coated - Oral, Suspension, Suspension - Intramuscular, Kit; Tablet, Kit; Tablet - Oral, Subcutaneous, Injection, suspension - Subcutaneous, Kit, Injection, suspension, extended release, Injection, suspension, extended release - Intramuscular, Injection, Injection - Intramuscular, Kit - Oral
Metastatic Renal Cell Carcinoma ( mRCC)
, 2.5 mg, 10.0 mg, 5.0 mg, 150.0 mg/mL, 400.0 mg/mL, 1.5 mg, 100.0 mg, 1040.0 mg/mL, 500.0 mg, 250.0 mg, 200.0 mg, 400.0 mg, 250.0 mg/mL, 50.0 mg/mL
, Oral, Tablet, Tablet - Oral, Intramuscular, Injection, suspension - Intramuscular, Injection, suspension, Tablet, sugar coated, Tablet, sugar coated - Oral, Suspension, Suspension - Intramuscular, Kit; Tablet, Kit; Tablet - Oral, Subcutaneous, Injection, suspension - Subcutaneous, Kit, Injection, suspension, extended release, Injection, suspension, extended release - Intramuscular, Injection, Injection - Intramuscular, Kit - Oral
Pharmaceutical Preparations
, 2.5 mg, 10.0 mg, 5.0 mg, 150.0 mg/mL, 400.0 mg/mL, 1.5 mg, 100.0 mg, 1040.0 mg/mL, 500.0 mg, 250.0 mg, 200.0 mg, 400.0 mg, 250.0 mg/mL, 50.0 mg/mL
, Oral, Tablet, Tablet - Oral, Intramuscular, Injection, suspension - Intramuscular, Injection, suspension, Tablet, sugar coated, Tablet, sugar coated - Oral, Suspension, Suspension - Intramuscular, Kit; Tablet, Kit; Tablet - Oral, Subcutaneous, Injection, suspension - Subcutaneous, Kit, Injection, suspension, extended release, Injection, suspension, extended release - Intramuscular, Injection, Injection - Intramuscular, Kit - Oral
Uterine hemorrhage
, 2.5 mg, 10.0 mg, 5.0 mg, 150.0 mg/mL, 400.0 mg/mL, 1.5 mg, 100.0 mg, 1040.0 mg/mL, 500.0 mg, 250.0 mg, 200.0 mg, 400.0 mg, 250.0 mg/mL, 50.0 mg/mL
, Oral, Tablet, Tablet - Oral, Intramuscular, Injection, suspension - Intramuscular, Injection, suspension, Tablet, sugar coated, Tablet, sugar coated - Oral, Suspension, Suspension - Intramuscular, Kit; Tablet, Kit; Tablet - Oral, Subcutaneous, Injection, suspension - Subcutaneous, Kit, Injection, suspension, extended release, Injection, suspension, extended release - Intramuscular, Injection, Injection - Intramuscular, Kit - Oral
Atrophic
, 2.5 mg, 10.0 mg, 5.0 mg, 150.0 mg/mL, 400.0 mg/mL, 1.5 mg, 100.0 mg, 1040.0 mg/mL, 500.0 mg, 250.0 mg, 200.0 mg, 400.0 mg, 250.0 mg/mL, 50.0 mg/mL
, Oral, Tablet, Tablet - Oral, Intramuscular, Injection, suspension - Intramuscular, Injection, suspension, Tablet, sugar coated, Tablet, sugar coated - Oral, Suspension, Suspension - Intramuscular, Kit; Tablet, Kit; Tablet - Oral, Subcutaneous, Injection, suspension - Subcutaneous, Kit, Injection, suspension, extended release, Injection, suspension, extended release - Intramuscular, Injection, Injection - Intramuscular, Kit - Oral
Hormonal Contraception
, 2.5 mg, 10.0 mg, 5.0 mg, 150.0 mg/mL, 400.0 mg/mL, 1.5 mg, 100.0 mg, 1040.0 mg/mL, 500.0 mg, 250.0 mg, 200.0 mg, 400.0 mg, 250.0 mg/mL, 50.0 mg/mL
, Oral, Tablet, Tablet - Oral, Intramuscular, Injection, suspension - Intramuscular, Injection, suspension, Tablet, sugar coated, Tablet, sugar coated - Oral, Suspension, Suspension - Intramuscular, Kit; Tablet, Kit; Tablet - Oral, Subcutaneous, Injection, suspension - Subcutaneous, Kit, Injection, suspension, extended release, Injection, suspension, extended release - Intramuscular, Injection, Injection - Intramuscular, Kit - Oral
Estrogen Replacement Therapy
, 2.5 mg, 10.0 mg, 5.0 mg, 150.0 mg/mL, 400.0 mg/mL, 1.5 mg, 100.0 mg, 1040.0 mg/mL, 500.0 mg, 250.0 mg, 200.0 mg, 400.0 mg, 250.0 mg/mL, 50.0 mg/mL
, Oral, Tablet, Tablet - Oral, Intramuscular, Injection, suspension - Intramuscular, Injection, suspension, Tablet, sugar coated, Tablet, sugar coated - Oral, Suspension, Suspension - Intramuscular, Kit; Tablet, Kit; Tablet - Oral, Subcutaneous, Injection, suspension - Subcutaneous, Kit, Injection, suspension, extended release, Injection, suspension, extended release - Intramuscular, Injection, Injection - Intramuscular, Kit - Oral
Vasomotor Symptoms Associated With Menopause
, 2.5 mg, 10.0 mg, 5.0 mg, 150.0 mg/mL, 400.0 mg/mL, 1.5 mg, 100.0 mg, 1040.0 mg/mL, 500.0 mg, 250.0 mg, 200.0 mg, 400.0 mg, 250.0 mg/mL, 50.0 mg/mL
, Oral, Tablet, Tablet - Oral, Intramuscular, Injection, suspension - Intramuscular, Injection, suspension, Tablet, sugar coated, Tablet, sugar coated - Oral, Suspension, Suspension - Intramuscular, Kit; Tablet, Kit; Tablet - Oral, Subcutaneous, Injection, suspension - Subcutaneous, Kit, Injection, suspension, extended release, Injection, suspension, extended release - Intramuscular, Injection, Injection - Intramuscular, Kit - Oral
Chronic Pain
, 2.5 mg, 10.0 mg, 5.0 mg, 150.0 mg/mL, 400.0 mg/mL, 1.5 mg, 100.0 mg, 1040.0 mg/mL, 500.0 mg, 250.0 mg, 200.0 mg, 400.0 mg, 250.0 mg/mL, 50.0 mg/mL
, Oral, Tablet, Tablet - Oral, Intramuscular, Injection, suspension - Intramuscular, Injection, suspension, Tablet, sugar coated, Tablet, sugar coated - Oral, Suspension, Suspension - Intramuscular, Kit; Tablet, Kit; Tablet - Oral, Subcutaneous, Injection, suspension - Subcutaneous, Kit, Injection, suspension, extended release, Injection, suspension, extended release - Intramuscular, Injection, Injection - Intramuscular, Kit - Oral
conjugated estrogen
, 2.5 mg, 10.0 mg, 5.0 mg, 150.0 mg/mL, 400.0 mg/mL, 1.5 mg, 100.0 mg, 1040.0 mg/mL, 500.0 mg, 250.0 mg, 200.0 mg, 400.0 mg, 250.0 mg/mL, 50.0 mg/mL
, Oral, Tablet, Tablet - Oral, Intramuscular, Injection, suspension - Intramuscular, Injection, suspension, Tablet, sugar coated, Tablet, sugar coated - Oral, Suspension, Suspension - Intramuscular, Kit; Tablet, Kit; Tablet - Oral, Subcutaneous, Injection, suspension - Subcutaneous, Kit, Injection, suspension, extended release, Injection, suspension, extended release - Intramuscular, Injection, Injection - Intramuscular, Kit - Oral
Birth Control
, 2.5 mg, 10.0 mg, 5.0 mg, 150.0 mg/mL, 400.0 mg/mL, 1.5 mg, 100.0 mg, 1040.0 mg/mL, 500.0 mg, 250.0 mg, 200.0 mg, 400.0 mg, 250.0 mg/mL, 50.0 mg/mL
, Oral, Tablet, Tablet - Oral, Intramuscular, Injection, suspension - Intramuscular, Injection, suspension, Tablet, sugar coated, Tablet, sugar coated - Oral, Suspension, Suspension - Intramuscular, Kit; Tablet, Kit; Tablet - Oral, Subcutaneous, Injection, suspension - Subcutaneous, Kit, Injection, suspension, extended release, Injection, suspension, extended release - Intramuscular, Injection, Injection - Intramuscular, Kit - Oral
Endometrial Hyperplasia
, 2.5 mg, 10.0 mg, 5.0 mg, 150.0 mg/mL, 400.0 mg/mL, 1.5 mg, 100.0 mg, 1040.0 mg/mL, 500.0 mg, 250.0 mg, 200.0 mg, 400.0 mg, 250.0 mg/mL, 50.0 mg/mL
, Oral, Tablet, Tablet - Oral, Intramuscular, Injection, suspension - Intramuscular, Injection, suspension, Tablet, sugar coated, Tablet, sugar coated - Oral, Suspension, Suspension - Intramuscular, Kit; Tablet, Kit; Tablet - Oral, Subcutaneous, Injection, suspension - Subcutaneous, Kit, Injection, suspension, extended release, Injection, suspension, extended release - Intramuscular, Injection, Injection - Intramuscular, Kit - Oral
Endometriosis
, 2.5 mg, 10.0 mg, 5.0 mg, 150.0 mg/mL, 400.0 mg/mL, 1.5 mg, 100.0 mg, 1040.0 mg/mL, 500.0 mg, 250.0 mg, 200.0 mg, 400.0 mg, 250.0 mg/mL, 50.0 mg/mL
, Oral, Tablet, Tablet - Oral, Intramuscular, Injection, suspension - Intramuscular, Injection, suspension, Tablet, sugar coated, Tablet, sugar coated - Oral, Suspension, Suspension - Intramuscular, Kit; Tablet, Kit; Tablet - Oral, Subcutaneous, Injection, suspension - Subcutaneous, Kit, Injection, suspension, extended release, Injection, suspension, extended release - Intramuscular, Injection, Injection - Intramuscular, Kit - Oral
metastatic Endometrial carcinoma
, 2.5 mg, 10.0 mg, 5.0 mg, 150.0 mg/mL, 400.0 mg/mL, 1.5 mg, 100.0 mg, 1040.0 mg/mL, 500.0 mg, 250.0 mg, 200.0 mg, 400.0 mg, 250.0 mg/mL, 50.0 mg/mL
, Oral, Tablet, Tablet - Oral, Intramuscular, Injection, suspension - Intramuscular, Injection, suspension, Tablet, sugar coated, Tablet, sugar coated - Oral, Suspension, Suspension - Intramuscular, Kit; Tablet, Kit; Tablet - Oral, Subcutaneous, Injection, suspension - Subcutaneous, Kit, Injection, suspension, extended release, Injection, suspension, extended release - Intramuscular, Injection, Injection - Intramuscular, Kit - Oral
Fracture
, 2.5 mg, 10.0 mg, 5.0 mg, 150.0 mg/mL, 400.0 mg/mL, 1.5 mg, 100.0 mg, 1040.0 mg/mL, 500.0 mg, 250.0 mg, 200.0 mg, 400.0 mg, 250.0 mg/mL, 50.0 mg/mL
, Oral, Tablet, Tablet - Oral, Intramuscular, Injection, suspension - Intramuscular, Injection, suspension, Tablet, sugar coated, Tablet, sugar coated - Oral, Suspension, Suspension - Intramuscular, Kit; Tablet, Kit; Tablet - Oral, Subcutaneous, Injection, suspension - Subcutaneous, Kit, Injection, suspension, extended release, Injection, suspension, extended release - Intramuscular, Injection, Injection - Intramuscular, Kit - Oral
Hot flashes
, 2.5 mg, 10.0 mg, 5.0 mg, 150.0 mg/mL, 400.0 mg/mL, 1.5 mg, 100.0 mg, 1040.0 mg/mL, 500.0 mg, 250.0 mg, 200.0 mg, 400.0 mg, 250.0 mg/mL, 50.0 mg/mL
, Oral, Tablet, Tablet - Oral, Intramuscular, Injection, suspension - Intramuscular, Injection, suspension, Tablet, sugar coated, Tablet, sugar coated - Oral, Suspension, Suspension - Intramuscular, Kit; Tablet, Kit; Tablet - Oral, Subcutaneous, Injection, suspension - Subcutaneous, Kit, Injection, suspension, extended release, Injection, suspension, extended release - Intramuscular, Injection, Injection - Intramuscular, Kit - Oral

Warnings

Medroxyprogesterone Acetate Contraindications
Condition
Risk Level
Notes
Thromboembolism
Do Not Combine
Breast
Do Not Combine
active thrombophlebitis
Do Not Combine
Neoplasms, Hormone-Dependent
Do Not Combine
Breast
Do Not Combine
Breast Cancer
Do Not Combine
Cerebrovascular Diseases
Do Not Combine
Vascular Diseases
Do Not Combine
Thromboembolism
Do Not Combine
Liver Disease
Do Not Combine
estrogen-dependent neoplasia
Do Not Combine
suspected pregnancy
Do Not Combine
Disease
Do Not Combine
undiagnosed abnormal genital bleeding
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Medroxyprogesterone Acetate may interact with Pulse Frequency
There are 20 known major drug interactions with Medroxyprogesterone Acetate.
Common Medroxyprogesterone Acetate Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The metabolism of Abemaciclib can be increased when combined with Medroxyprogesterone acetate.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be increased when combined with Medroxyprogesterone acetate.
Alectinib
Major
The metabolism of Alectinib can be increased when combined with Medroxyprogesterone acetate.
Alpelisib
Major
The metabolism of Alpelisib can be increased when combined with Medroxyprogesterone acetate.
Aminophylline
Major
The metabolism of Aminophylline can be increased when combined with Medroxyprogesterone acetate.
Medroxyprogesterone Acetate Toxicity & Overdose RiskThe lowest toxic dose of medroxyprogesterone acetate in rats has been found to be greater than 6400mg/kg and greater than 16g/kg in mice. Overdosing on MPA may cause nausea, vomiting, breast tenderness, dizziness, abdominal pain, drowsiness, fatigue, and menstrual bleeding. If a patient receives too much of a MPA injection, they should seek medical help immediately. Treatment involves stopping the MPA and providing symptomatic care.
image of a doctor in a lab doing drug, clinical research

Medroxyprogesterone Acetate Novel Uses: Which Conditions Have a Clinical Trial Featuring Medroxyprogesterone Acetate?

406 active clinical trials are presently assessing the potential of Medroxyprogesterone Acetate for the management of Osteoporosis, Amenorrhea and Hormonal Contraception.
Condition
Clinical Trials
Trial Phases
conjugated estrogen
0 Actively Recruiting
Vasomotor Symptoms Associated With Menopause
1 Actively Recruiting
Phase 3
Birth Control
31 Actively Recruiting
Not Applicable, Phase 3, Phase 4, Early Phase 1
Osteoporosis
40 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Early Phase 1, Phase 4, Phase 3
Endometriosis
1 Actively Recruiting
Phase 4
metastatic Endometrial carcinoma
0 Actively Recruiting
Endometriosis
32 Actively Recruiting
Phase 3, Not Applicable, Early Phase 1, Phase 2, Phase 4, Phase 1
Hormonal Contraception
0 Actively Recruiting
hypoestrogenism
2 Actively Recruiting
Phase 4
Postmenopausal Osteoporosis
3 Actively Recruiting
Not Applicable, Phase 4
Uterine hemorrhage
3 Actively Recruiting
Phase 3, Phase 2, Not Applicable
Pharmaceutical Preparations
0 Actively Recruiting
Estrogen Replacement Therapy
0 Actively Recruiting
Amenorrhea
3 Actively Recruiting
Not Applicable, Phase 1
Fracture
0 Actively Recruiting
Atrophic
5 Actively Recruiting
Phase 2, Phase 4, Not Applicable
Endometrial Hyperplasia
9 Actively Recruiting
Phase 2, Not Applicable
Chronic Pain
175 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 1, Phase 4, Early Phase 1
Pharmaceutical Preparations
0 Actively Recruiting
Metastatic Renal Cell Carcinoma ( mRCC)
39 Actively Recruiting
Phase 3, Phase 1, Phase 2, Not Applicable

Medroxyprogesterone Acetate Reviews: What are patients saying about Medroxyprogesterone Acetate?

5Patient Review
10/11/2019
Medroxyprogesterone Acetate for Abnormal Uterine Bleeding caused by Imbalance of Hormones
This medication has helped me to regulate my periods. The only downside is that it makes me feel drowsy.
5Patient Review
10/21/2020
Medroxyprogesterone Acetate for Absence of Menstrual Periods in Woman Who Has Had Them
Provera completely jumpstarted my period after three months of no activity. I was on day 8 when it finally arrived, and have been very pleased with the results.
5Patient Review
4/28/2018
Medroxyprogesterone Acetate for Absence of Menstrual Periods in Woman Who Has Had Them
This drug was very effective in inducing a period. I took it for ten days and started my period around day seven or eight. It lasted for fourteen days. The second time I took this drug was for five days at 10mg to start a period and then take clomid. My period started three days after finishing the prescription. Besides mild cramping, I had no side effects, which is unusual for me when it comes to periods.
5Patient Review
3/15/2021
Medroxyprogesterone Acetate for Absence of Menstrual Periods in Woman Who Has Had Them
I'm on my second round of this medication. I have abnormal periods; I will ovulate but not shed the lining. Last year, when taking this medication, I did bleed heavily and have larger clots. But that was because I was getting rid of months of lining. I had mild cramping, which is normal for me. We are trying to conceive but no luck. Hoping this works as well as it did the first time.
3.7Patient Review
5/30/2019
Medroxyprogesterone Acetate for Absence of Menstrual Periods in Woman Who Has Had Them
I was prescribed this medication for heavy menstrual bleeding, and it definitely helped to lighten my flow and reduce the amount of blood clots. However, my period lasted longer than usual (nine days instead of the seven), which was a bit inconvenient.
3.7Patient Review
5/28/2021
Medroxyprogesterone Acetate for Prevention of Abnormal Growth in Cells of Uterine Lining
I had heavy, long periods for a few years before my doctor recommended a D&C. I started taking PROVERA for 10 days, and on the 10th day I started spotting. The bleeding became heavier and then I was rushed to the ER because I felt weak and dizzy. My hemoglobin levels were very low, but after getting 2 units of blood and 3L of fluids, the bleeding stopped.
3.7Patient Review
10/26/2022
Medroxyprogesterone Acetate for Abnormal Uterine Bleeding caused by Imbalance of Hormones
I've only been taking this medication for a few days, and it has already successfully stopped my period. However, I have started to feel nauseous since the third day of taking it, and this feeling is getting worse as time goes on.
3.3Patient Review
7/11/2022
Medroxyprogesterone Acetate for Abnormal Uterine Bleeding caused by Imbalance of Hormones
My gynecologist prescribed this to me in order to stop the bleeding that started six years after my uterus was ablated. So far, it's been successful in keeping the bleeding at bay; however, I have been feeling extra tired and crampy. I'm hoping this will stop soon.
3Patient Review
6/6/2022
Medroxyprogesterone Acetate for Test for the Presence of Estrogen in the Body
My OBGYN prescribed this medication for me to use over the course of 90 days in order to help regulate my irregular menstrual cycles. I was told that it would lighten my flow, which it has done; however, I've been bleeding and spotting for 3 weeks straight now, which is a bit much. Additionally, I've experienced mood swings and constant thirstiness since starting the medication.
3Patient Review
8/17/2022
Medroxyprogesterone Acetate for Absence of Menstrual Periods in Woman Who Has Had Them
I started taking this medication yesterday because I have PCOS, and I've been experiencing a lot of pelvic and lower back pain. So far, I haven't seen any results, but I'm hopeful that this will help me to become more regular again.
2.7Patient Review
1/10/2022
Medroxyprogesterone Acetate for Prevention of Abnormal Growth in Cells of Uterine Lining
Though it did what it was supposed to do in terms of stopping my heavy bleeding, I found the side effects really intolerable.
2.3Patient Review
7/23/2020
Medroxyprogesterone Acetate for Abnormal Uterine Bleeding caused by Imbalance of Hormones
I was prescribed this medication on 5/29 and have been bleeding for 55 days straight. I went back to the doctor and all they offered me was a dnc.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about medroxyprogesterone acetate

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is medroxyprogesterone used for abortion?

"MPA was found to be not significantly different and is considered to be safe to use during pregnancy. It is unlikely to cause an abnormal fetus or lead to a miscarriage. Although this report does not address how effective MPA is, it seems to be a safe drug to use during pregnancy."

Answered by AI

What are the side effects of medroxyprogesterone acetate?

"If you experience any of the following side effects, tell your doctor or pharmacist: nausea, bloating, breast tenderness, headache, change in vaginal discharge, mood swings, blurred vision, dizziness, drowsiness, or weight gain/loss."

Answered by AI

Is medroxyprogesterone a steroid?

"Medroxyprogesterone is a synthetic progestin and oral contraceptive. It is structurally similar to the hormone progesterone and is used for a variety of purposes including contraception, menopausal hormone therapy, and treatment of endometriosis."

Answered by AI

Clinical Trials for Medroxyprogesterone Acetate

Have you considered Medroxyprogesterone Acetate clinical trials? We made a collection of clinical trials featuring Medroxyprogesterone Acetate, we think they might fit your search criteria.
Have you considered Medroxyprogesterone Acetate clinical trials? We made a collection of clinical trials featuring Medroxyprogesterone Acetate, we think they might fit your search criteria.
Have you considered Medroxyprogesterone Acetate clinical trials? We made a collection of clinical trials featuring Medroxyprogesterone Acetate, we think they might fit your search criteria.