Kantrex

Bacterial Infection caused by Klebsiella Pneumoniae, Bacterial Infections, Acinetobacter Infections + 3 more
Treatment
0 Active Studies for Kantrex

What is Kantrex

KanamycinThe Generic name of this drug
Treatment SummaryKanamycin is an antibiotic used to treat bacterial infections. It is available in pill, intravenous, and intramuscular forms and is derived from the bacterium Streptomyces kanamyceticus. Kanamycin sulfate is the most common form of the drug.
Kanamycinis the brand name
Kantrex Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Kanamycin
Kanamycin
2003
2

Effectiveness

How Kantrex Affects PatientsKanamycin is an antibiotic used to fight against certain types of bacteria, like Pseudomonas, Acinetobacter, Enterobacter, and some types of mycobacteria (the bacteria causing tuberculosis). It works by interfering with the ability of the bacteria to make proteins needed for it to survive. It is less effective against other types of bacteria, fungi, and viruses. In the past, it has been used with other antibiotics to fight against streptococcal infections, particularly endocarditis.
How Kantrex works in the bodyKanamycin works by blocking certain proteins and RNA molecules from working properly. It binds to four pieces of RNA and one protein in the 30S subunit, and prevents them from correctly decoding the genetic information they need to create proteins. When they can't do this, the proteins they produce are either nonfunctional or toxic, which interrupts the process of creating proteins and breaks up polysomes into nonfunctional monosomes.

When to interrupt dosage

The endorsed dosage of Kantrex relies upon the recognized condition, including Bacterial Infections, Bacterial Infection caused by Klebsiella Pneumoniae and Bacterial Infections. The measure of dosage is contingent upon the method of delivery (e.g. Injection, solution or Intramuscular; Intravenous) featured in the table below.
Condition
Dosage
Administration
Bacterial Infection caused by Klebsiella Pneumoniae
, 333.0 mg/mL, 1000.0 mg/mL
, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intraperitoneal; Intravenous; Irrigation; Respiratory (inhalation), Injection, solution - Intramuscular; Intraperitoneal; Intravenous; Irrigation; Respiratory (inhalation)
Bacterial Infections
, 333.0 mg/mL, 1000.0 mg/mL
, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intraperitoneal; Intravenous; Irrigation; Respiratory (inhalation), Injection, solution - Intramuscular; Intraperitoneal; Intravenous; Irrigation; Respiratory (inhalation)
Acinetobacter Infections
, 333.0 mg/mL, 1000.0 mg/mL
, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intraperitoneal; Intravenous; Irrigation; Respiratory (inhalation), Injection, solution - Intramuscular; Intraperitoneal; Intravenous; Irrigation; Respiratory (inhalation)
Bacterial Infections
, 333.0 mg/mL, 1000.0 mg/mL
, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intraperitoneal; Intravenous; Irrigation; Respiratory (inhalation), Injection, solution - Intramuscular; Intraperitoneal; Intravenous; Irrigation; Respiratory (inhalation)
Bacterial Infections
, 333.0 mg/mL, 1000.0 mg/mL
, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intraperitoneal; Intravenous; Irrigation; Respiratory (inhalation), Injection, solution - Intramuscular; Intraperitoneal; Intravenous; Irrigation; Respiratory (inhalation)
Bacterial Infection caused by Enterobacter aerogenes
, 333.0 mg/mL, 1000.0 mg/mL
, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intraperitoneal; Intravenous; Irrigation; Respiratory (inhalation), Injection, solution - Intramuscular; Intraperitoneal; Intravenous; Irrigation; Respiratory (inhalation)

Warnings

Kantrex Contraindications
Condition
Risk Level
Notes
long term therapy
Do Not Combine
There are 20 known major drug interactions with Kantrex.
Common Kantrex Drug Interactions
Drug Name
Risk Level
Description
Neomycin
Major
The risk or severity of nephrotoxicity can be increased when Kanamycin is combined with Neomycin.
Tenofovir
Major
Kanamycin may increase the nephrotoxic activities of Tenofovir.
Tenofovir alafenamide
Major
Kanamycin may increase the nephrotoxic activities of Tenofovir alafenamide.
Tenofovir disoproxil
Major
Kanamycin may increase the nephrotoxic activities of Tenofovir disoproxil.
Vibrio cholerae CVD 103-HgR strain live antigen
Major
The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Kanamycin.
Kantrex Toxicity & Overdose RiskAmikacin has mild, temporary side effects on the kidneys in 5-25% of patients, and can cause permanent hearing damage in a small number of cases. It is particularly dangerous to the inner ear, where it can lead to hearing loss and dizziness. An overdose of Amikacin is considered to be over 17500mg/kg in mice, over 4g/kg in rats, and over 3g/kg in rabbits.

Kantrex Novel Uses: Which Conditions Have a Clinical Trial Featuring Kantrex?

Currently, there are no active clinical trials assessing the potential of Kantrex in treating Bacterial Infection caused by Acinetobacter species, Bacterial Infections and Bacterial Infection caused by Enterobacter aerogenes.
Condition
Clinical Trials
Trial Phases
Acinetobacter Infections
0 Actively Recruiting
Bacterial Infections
0 Actively Recruiting
Bacterial Infection caused by Enterobacter aerogenes
0 Actively Recruiting
Bacterial Infections
0 Actively Recruiting
Bacterial Infections
0 Actively Recruiting
Bacterial Infection caused by Klebsiella Pneumoniae
0 Actively Recruiting

Patient Q&A Section about kantrex

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the generic name for kanamycin?

"Kanamycin is an antibiotic used to treat bacterial infections. It is in the class of drugs called aminoglycosides."

Answered by AI

What is Kantrex used for?

"Kantrex is a prescription medication used to treat the symptoms of serious bacterial infections. Kantrex can be used by itself or with other medications. Kantrex is part of a class of drugs known as Aminoglycosides."

Answered by AI

What is tetracycline used to treat?

"Tetracycline antibiotics are used to treat infections and to help control acne. Demeclocycline, doxycycline, and minocycline are also sometimes used to treat other conditions as prescribed by a doctor. Tetracycline antibiotics will not work for treating colds, flu, or other viral infections."

Answered by AI

What is kanamycin used for?

"Kanamycin injection is used to treat serious bacterial infections. This medicine is for short-term use only. Kanamycin belongs to the class of medicines known as aminoglycoside antibiotics. It works by killing bacteria or preventing their growth."

Answered by AI
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