Kantrex

Bacterial Infection caused by Klebsiella Pneumoniae, Bacterial Infections, Acinetobacter Infections + 3 more

Treatment

0 Active Studies for Kantrex

Treatment for

Bacterial Infection caused by Klebsiella Pneumoniae

What is Kantrex

Kanamycin

The Generic name of this drug

Treatment Summary

Kanamycin is an antibiotic used to treat bacterial infections. It is available in pill, intravenous, and intramuscular forms and is derived from the bacterium Streptomyces kanamyceticus. Kanamycin sulfate is the most common form of the drug.

Kanamycin

is the brand name

Kantrex Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Kanamycin

2003

Effectiveness

How Kantrex Affects Patients

Kanamycin is an antibiotic used to fight against certain types of bacteria, like Pseudomonas, Acinetobacter, Enterobacter, and some types of mycobacteria (the bacteria causing tuberculosis). It works by interfering with the ability of the bacteria to make proteins needed for it to survive. It is less effective against other types of bacteria, fungi, and viruses. In the past, it has been used with other antibiotics to fight against streptococcal infections, particularly endocarditis.

How Kantrex works in the body

Kanamycin works by blocking certain proteins and RNA molecules from working properly. It binds to four pieces of RNA and one protein in the 30S subunit, and prevents them from correctly decoding the genetic information they need to create proteins. When they can't do this, the proteins they produce are either nonfunctional or toxic, which interrupts the process of creating proteins and breaks up polysomes into nonfunctional monosomes.

When to interrupt dosage

The endorsed dosage of Kantrex relies upon the recognized condition, including Bacterial Infections, Bacterial Infection caused by Klebsiella Pneumoniae and Bacterial Infections. The measure of dosage is contingent upon the method of delivery (e.g. Injection, solution or Intramuscular; Intravenous) featured in the table below.

Condition

Dosage

Administration

Bacterial Infection caused by Klebsiella Pneumoniae

, 333.0 mg/mL, 1000.0 mg/mL

, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intraperitoneal; Intravenous; Irrigation; Respiratory (inhalation), Injection, solution - Intramuscular; Intraperitoneal; Intravenous; Irrigation; Respiratory (inhalation)

Bacterial Infections

, 333.0 mg/mL, 1000.0 mg/mL

Acinetobacter Infections

, 333.0 mg/mL, 1000.0 mg/mL

Bacterial Infections

, 333.0 mg/mL, 1000.0 mg/mL

Bacterial Infections

, 333.0 mg/mL, 1000.0 mg/mL

Bacterial Infection caused by Enterobacter aerogenes

, 333.0 mg/mL, 1000.0 mg/mL

Warnings

Kantrex Contraindications

Condition

Risk Level

Notes

long term therapy

Do Not Combine

There are 20 known major drug interactions with Kantrex.

Common Kantrex Drug Interactions

Drug Name

Risk Level

Description

Neomycin

Major

The risk or severity of nephrotoxicity can be increased when Kanamycin is combined with Neomycin.

Tenofovir

Major

Kanamycin may increase the nephrotoxic activities of Tenofovir.

Tenofovir alafenamide

Major

Kanamycin may increase the nephrotoxic activities of Tenofovir alafenamide.

Tenofovir disoproxil

Major

Kanamycin may increase the nephrotoxic activities of Tenofovir disoproxil.

Vibrio cholerae CVD 103-HgR strain live antigen

Major

The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Kanamycin.

Kantrex Toxicity & Overdose Risk

Amikacin has mild, temporary side effects on the kidneys in 5-25% of patients, and can cause permanent hearing damage in a small number of cases. It is particularly dangerous to the inner ear, where it can lead to hearing loss and dizziness. An overdose of Amikacin is considered to be over 17500mg/kg in mice, over 4g/kg in rats, and over 3g/kg in rabbits.

Kantrex Novel Uses: Which Conditions Have a Clinical Trial Featuring Kantrex?

Currently, there are no active clinical trials assessing the potential of Kantrex in treating Bacterial Infection caused by Acinetobacter species, Bacterial Infections and Bacterial Infection caused by Enterobacter aerogenes.

Condition

Clinical Trials

Trial Phases

Acinetobacter Infections

0 Actively Recruiting

Bacterial Infections

0 Actively Recruiting

Bacterial Infection caused by Enterobacter aerogenes

0 Actively Recruiting

Bacterial Infections

0 Actively Recruiting

Bacterial Infections

0 Actively Recruiting

Bacterial Infection caused by Klebsiella Pneumoniae

0 Actively Recruiting

Patient Q&A Section about kantrex

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the generic name for kanamycin?

"Kanamycin is an antibiotic used to treat bacterial infections. It is in the class of drugs called aminoglycosides."

Answered by AI

What is Kantrex used for?

"Kantrex is a prescription medication used to treat the symptoms of serious bacterial infections. Kantrex can be used by itself or with other medications. Kantrex is part of a class of drugs known as Aminoglycosides."

Answered by AI

What is tetracycline used to treat?

"Tetracycline antibiotics are used to treat infections and to help control acne. Demeclocycline, doxycycline, and minocycline are also sometimes used to treat other conditions as prescribed by a doctor. Tetracycline antibiotics will not work for treating colds, flu, or other viral infections."

Answered by AI

What is kanamycin used for?

"Kanamycin injection is used to treat serious bacterial infections. This medicine is for short-term use only. Kanamycin belongs to the class of medicines known as aminoglycoside antibiotics. It works by killing bacteria or preventing their growth."

Answered by AI