Iressa

Q: What is Iressa used to treat?

<p>This medication is used to treat <a href="https://www.withpower.com/clinical-trials/lung-cancer">lung cancer</a>. It works by interfering with the growth of cancer cells.</p>

Malignant Neoplasms, Treatment Naive

Treatment

3 FDA approvals

4 Active Studies for Iressa

Treatment for

Malignant Neoplasms

What is Iressa

GefitinibThe Generic name of this drug

Treatment SummaryGefitinib (also known as Iressa) is a medication used to treat certain types of cancer. It works by targeting mutated proteins in cancer cells, similar to another drug called erlotinib (marketed as Tarceva). Gefitinib is manufactured by AstraZeneca and is available in many countries.

Iressais the brand name

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Iressa Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Iressa

Gefitinib

2015

Approved as Treatment by the FDA

Gefitinib, otherwise called Iressa, is approved by the FDA for 3 uses which include Metastatic Non-Small Cell Lung Cancer and Treatment Naive .

Metastatic Non-Small Cell Lung Cancer

Treatment Naive

Malignant Neoplasms

Effectiveness

How Iressa Affects PatientsGefitinib stops certain proteins in cells from becoming activated. It specifically targets epidermal growth factor receptor (EGFR) proteins, which are found on the surfaces of many normal and cancerous cells. By blocking these proteins, it helps to inhibit cell growth.

How Iressa works in the bodyGefitinib is a drug that targets the epidermal growth factor receptor (EGFR). This receptor is often found in higher amounts in cancerous cells like those found in lung or breast cancer. By blocking the EGFR, Gefitinib stops the cancer cells from growing and propagating. It is the first drug able to selectively target the EGFR tyrosine kinase and reduce the survival of cancer cells.

When to interrupt dosage

The measure of Iressa is contingent upon the diagnosed disorder. The quantity of dosage fluctuates, in line with the technique of administration outlined in the table beneath.

Condition

Dosage

Administration

Malignant Neoplasms

, 250.0 mg

Tablet - Oral, , Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral

Treatment Naive

, 250.0 mg

Tablet - Oral, , Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral

Warnings

There are 20 known major drug interactions with Iressa.

Common Iressa Drug Interactions

Drug Name

Risk Level

Description

Amoxapine

Major

The metabolism of Amoxapine can be decreased when combined with Gefitinib.

Astemizole

Major

The metabolism of Astemizole can be decreased when combined with Gefitinib.

Axitinib

Major

The metabolism of Axitinib can be decreased when combined with Gefitinib.

Cabazitaxel

Major

The metabolism of Cabazitaxel can be decreased when combined with Gefitinib.

Clomipramine

Major

The metabolism of Clomipramine can be decreased when combined with Gefitinib.

Iressa Toxicity & Overdose RiskGefitinib is generally safe in doses up to 500mg, but can be fatal to rats when taken in extremely high doses. Mice were unaffected by doses that were half as high. Common symptoms of overdose include diarrhea and skin rash.

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Iressa Novel Uses: Which Conditions Have a Clinical Trial Featuring Iressa?

Nine investigations are presently investigating the potential of Iressa as a Treatment Naive remedy.

Condition

Clinical Trials

Trial Phases

Treatment Naive

0 Actively Recruiting

Malignant Neoplasms

4 Actively Recruiting

Phase 1, Phase 2

Iressa Reviews: What are patients saying about Iressa?

5Patient Review

1/30/2014

Iressa for Non-Small Cell Lung Cancer

I had cancer in the left lung and bronchial area. I underwent a pneumonectomy to remove my left lung in January 2004, and have been taking Iressa every day since. I feel it has kept the cancer at bay.

1.7Patient Review

2/13/2017

Iressa for Epidermal Growth Factor Receptor Positive Non-Small Cell Lung Cancer

I've been taking Iressa for three months to treat non small cell lung cancer that has metastasized to my bones. My latest CT scan showed another lesion in my bone. The drug also caused very dry skin, itching scalp, acne, mouth sores, and cramps in my legs.

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Patient Q&A Section about iressa

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is Iressa used to treat?

"This medication is used to treat lung cancer. It works by interfering with the growth of cancer cells."

Answered by AI

What does gefitinib do to your body?

"Gefitinib is an antineoplastic, meaning it is a cancer medication. It works by interfering with the growth of cancer cells, which eventually leads to their destruction. This medicine can only be obtained with a prescription from a doctor."

Answered by AI

Can Iressa cure lung cancer?

"Iressa may extend life for a period of four to eighteen months in some patients, though it does not cure cancer. Small cell lung cancer is treated differently by Iressa."

Answered by AI

Is Iressa chemotherapy?

"A targeted therapy for lung cancer known as Iressa has been found to be as effective as chemotherapy with far fewer side effects, according to an international Phase III clinical trial."

Answered by AI