Iressa
Malignant Neoplasms, Treatment Naive
Treatment
3 FDA approvals
1 Active Study for Iressa
Treatment for
Malignant Neoplasms
What is Iressa
Gefitinib
The Generic name of this drug
Treatment Summary
Gefitinib (also known as Iressa) is a medication used to treat certain types of cancer. It works by targeting mutated proteins in cancer cells, similar to another drug called erlotinib (marketed as Tarceva). Gefitinib is manufactured by AstraZeneca and is available in many countries.
Iressa
is the brand name
Iressa Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Iressa
Gefitinib
2015
2
Approved as Treatment by the FDA
Gefitinib, otherwise called Iressa, is approved by the FDA for 3 uses which include Metastatic Non-Small Cell Lung Cancer and Treatment Naive .
Metastatic Non-Small Cell Lung Cancer
Treatment Naive
Malignant Neoplasms
Effectiveness
How Iressa Affects Patients
Gefitinib stops certain proteins in cells from becoming activated. It specifically targets epidermal growth factor receptor (EGFR) proteins, which are found on the surfaces of many normal and cancerous cells. By blocking these proteins, it helps to inhibit cell growth.
How Iressa works in the body
Gefitinib is a drug that targets the epidermal growth factor receptor (EGFR). This receptor is often found in higher amounts in cancerous cells like those found in lung or breast cancer. By blocking the EGFR, Gefitinib stops the cancer cells from growing and propagating. It is the first drug able to selectively target the EGFR tyrosine kinase and reduce the survival of cancer cells.
When to interrupt dosage
The measure of Iressa is contingent upon the diagnosed disorder. The quantity of dosage fluctuates, in line with the technique of administration outlined in the table beneath.
Condition
Dosage
Administration
Malignant Neoplasms
, 250.0 mg
, Tablet - Oral, Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated - Oral, Tablet, coated
Treatment Naive
, 250.0 mg
, Tablet - Oral, Oral, Tablet, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated - Oral, Tablet, coated
Warnings
There are 20 known major drug interactions with Iressa.
Common Iressa Drug Interactions
Drug Name
Risk Level
Description
Amoxapine
Major
The metabolism of Amoxapine can be decreased when combined with Gefitinib.
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Gefitinib.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Gefitinib.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Gefitinib.
Clomipramine
Major
The metabolism of Clomipramine can be decreased when combined with Gefitinib.
Iressa Toxicity & Overdose Risk
Gefitinib is generally safe in doses up to 500mg, but can be fatal to rats when taken in extremely high doses. Mice were unaffected by doses that were half as high. Common symptoms of overdose include diarrhea and skin rash.
Iressa Novel Uses: Which Conditions Have a Clinical Trial Featuring Iressa?
Nine investigations are presently investigating the potential of Iressa as a Treatment Naive remedy.
Condition
Clinical Trials
Trial Phases
Treatment Naive
0 Actively Recruiting
Malignant Neoplasms
3 Actively Recruiting
Phase 1, Phase 2
Iressa Reviews: What are patients saying about Iressa?
5
Patient Review
1/30/2014
Iressa for Non-Small Cell Lung Cancer
1.7
Patient Review
2/13/2017
Iressa for Epidermal Growth Factor Receptor Positive Non-Small Cell Lung Cancer
Patient Q&A Section about iressa
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
What is Iressa used to treat?
"This medication is used to treat lung cancer. It works by interfering with the growth of cancer cells."
Answered by AI
What does gefitinib do to your body?
"Gefitinib is an antineoplastic, meaning it is a cancer medication. It works by interfering with the growth of cancer cells, which eventually leads to their destruction. This medicine can only be obtained with a prescription from a doctor."
Answered by AI
Can Iressa cure lung cancer?
"Iressa may extend life for a period of four to eighteen months in some patients, though it does not cure cancer. Small cell lung cancer is treated differently by Iressa."
Answered by AI
Is Iressa chemotherapy?
"A targeted therapy for lung cancer known as Iressa has been found to be as effective as chemotherapy with far fewer side effects, according to an international Phase III clinical trial."
Answered by AI