Inomax

Pulmonary Hypertension, Respiratory Failure
Treatment
20 Active Studies for Inomax

What is Inomax

Nitric OxideThe Generic name of this drug
Treatment SummaryNitric oxide, also known as nitrogen monoxide, is a colorless, odorless gas with the chemical formula NO. It is a signaling molecule in mammals and is widely used in the chemical industry. It is also produced as a byproduct by car engines and power plants and is a toxic air pollutant. Nitric oxide should not be confused with nitrous oxide (N2O), which is an anesthetic, or nitrogen dioxide (NO2), which is also a poisonous air pollutant. Nitric oxide is a free radical, making it highly reactive and reactive with ozone in the air to form nitrogen dioxide, which can be
INOmaxis the brand name
Inomax Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
INOmax
Nitric Oxide
1999
7

Effectiveness

How Inomax Affects PatientsPersistent pulmonary hypertension of the newborn (PPHN) can be caused by a number of different conditions, such as meconium aspiration syndrome, pneumonia, and sepsis. This leads to high pulmonary vascular resistance, which decreases oxygen in the blood. Nitric oxide can help with this by widening the pulmonary vessels in healthy parts of the lung and re-distributing blood flow away from the unhealthy parts. This increases the oxygen in the blood.
How Inomax works in the bodyNitric oxide helps arteries and veins relax, allowing more blood to flow. This process happens when nitric oxide binds to a molecule found in cells, activating a chemical reaction which produces a compound that causes the vessels to relax. When inhaled, nitric oxide helps the lungs open up, allowing for easier breathing.

When to interrupt dosage

The quantity of Inomax is contingent upon the established condition. The amount of dosage fluctuates as per the strategy of delivery mentioned in the table below.
Condition
Dosage
Administration
Pulmonary Hypertension
0.00098 mg/mL, , 0.005 mL/mL, 0.000123 mg/mL, 800.0 ppm, 100.0 ppm, 400.0 ppm, 0.01 %, 0.08 %, 0.1 mg/mL, 0.8 mg/mL, 11.157 mg/mL
, Respiratory (inhalation), Gas, Gas - Respiratory (inhalation), Inhalant, Inhalant - Respiratory (inhalation), Liquid, Topical, Liquid - Topical
Respiratory Failure
0.00098 mg/mL, , 0.005 mL/mL, 0.000123 mg/mL, 800.0 ppm, 100.0 ppm, 400.0 ppm, 0.01 %, 0.08 %, 0.1 mg/mL, 0.8 mg/mL, 11.157 mg/mL
, Respiratory (inhalation), Gas, Gas - Respiratory (inhalation), Inhalant, Inhalant - Respiratory (inhalation), Liquid, Topical, Liquid - Topical

Warnings

Inomax Contraindications
Condition
Risk Level
Notes
Cerebrospinal fluid shunts procedure
Do Not Combine
There are 20 known major drug interactions with Inomax.
Common Inomax Drug Interactions
Drug Name
Risk Level
Description
Eliglustat
Major
The metabolism of Eliglustat can be decreased when combined with Nitric Oxide.
Fentanyl
Major
The metabolism of Fentanyl can be decreased when combined with Nitric Oxide.
Abacavir
Minor
Nitric Oxide may decrease the excretion rate of Abacavir which could result in a higher serum level.
Acebutolol
Minor
The risk or severity of adverse effects can be increased when Nitric Oxide is combined with Acebutolol.
Aclidinium
Minor
Nitric Oxide may decrease the excretion rate of Aclidinium which could result in a higher serum level.

Inomax Novel Uses: Which Conditions Have a Clinical Trial Featuring Inomax?

22 active studies are examining the potential of Inomax in providing therapeutic relief for Respiratory Failure.
Condition
Clinical Trials
Trial Phases
Pulmonary Hypertension
29 Actively Recruiting
Phase 3, Phase 2, Not Applicable, Phase 1, Early Phase 1
Respiratory Failure
0 Actively Recruiting

Patient Q&A Section about inomax

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is INOmax system?

"INOMAX is an inhaler that helps improve blood flow to the lungs and prevents hypoxic respiratory failure in term and near-term neonates."

Answered by AI

What is INOmax used for?

"INOmax is combined with artificial ventilation and other medicines to help improve blood oxygen levels in the following groups of patients: newborn babies (born after 34 weeks of gestation) with breathing problems associated with pulmonary hypertension (high blood pressure in the lungs)."

Answered by AI

What is inhaled nitric oxide used for?

"Nitric oxide is used to treat term and near-term babies with respiratory failure that is caused by pulmonary hypertension. Nitric oxide is a gas that is inhaled through the nose or mouth."

Answered by AI

What is INOmax Dsir?

"The Inomax DSIR. Plus MRI delivery system is indicated for use with Inomax (nitric oxide for inhalation) to provide a constant concentration of nitric oxide (NO) to the patient throughout the inspired breath."

Answered by AI

Clinical Trials for Inomax

Have you considered Inomax clinical trials? We made a collection of clinical trials featuring Inomax, we think they might fit your search criteria.Go to Trials
Have you considered Inomax clinical trials? We made a collection of clinical trials featuring Inomax, we think they might fit your search criteria.Go to Trials
Have you considered Inomax clinical trials? We made a collection of clinical trials featuring Inomax, we think they might fit your search criteria.Go to Trials
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