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Temporo-masseteric Nerve Block for Acute Pain

Phase 2
Recruiting
Led By Gayathri D Subramanian, PhD, DMD
Research Sponsored by Rutgers, The State University of New Jersey
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Age 18 years of age or older (up to 64 years)
ASA 1 and 2 (mild or absent systemic illnesses, deemed fit for undergoing dental extractions under intravenous sedation)
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, post-procedure (day 1) and at post-operative visit (day 8)
Awards & highlights

Study Summary

This trial is testing whether a nerve block can reduce pain for people getting their lower wisdom teeth removed while sedated. People will be asked about their pain and pain meds use for a week after the procedure, and then checked in on 8 days later.

Who is the study for?
This trial is for adults aged 18-64 who need their lower wisdom teeth removed and can consent to the study. They must be healthy enough for sedation, not pregnant, have internet access with a smartphone, and able to take common pain meds like Tylenol or Advil.Check my eligibility
What is being tested?
The study tests if a local anesthetic injection called Temporo-masseteric Nerve Block reduces pain after wisdom tooth removal under sedation. Participants will report their pain levels and medication use over the first week post-surgery.See study design
What are the potential side effects?
Potential side effects may include discomfort at the injection site, possible allergic reactions to the anesthetic used in the nerve block, and typical risks associated with dental procedures such as swelling or infection.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I am between 18 and 64 years old.
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I am healthy enough for dental surgery with sedation.
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I understand the details of the clinical trial and can give informed consent.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, post-procedure (day 1) and at post-operative visit (day 8)
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, post-procedure (day 1) and at post-operative visit (day 8) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Adverse effects
Masticatory muscle pain to palpation- Temporalis and Masseter
Mean Numerical Pain Rating Scale pain score
+3 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: Temporo-masseteric Nerve Block (TMNB) Injection with Local AnestheticExperimental Treatment1 Intervention
Following lower third molar extraction under intravenous sedation, the patient will receive the TMNB local anesthetic nerve block using the standard dental local anesthetic, i.e,. 2% lidocaine with 1:100,000 epinephrine, on the side/s of lower wisdom molar extraction/s

Find a Location

Who is running the clinical trial?

Rutgers, The State University of New JerseyLead Sponsor
429 Previous Clinical Trials
64,212 Total Patients Enrolled
2 Trials studying Acute Pain
144 Patients Enrolled for Acute Pain
Gayathri D Subramanian, PhD, DMDPrincipal InvestigatorRutgers School of Dental Medicine

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What potential hazards should patients be aware of prior to receiving a Temporo-masseteric Nerve Block?

"Our team at Power has assessed the safety of Temporo-masseteric Nerve Block to be a 2, meaning there is some existing evidence that supports its safety but not efficacy."

Answered by AI

Could I fulfill the criteria to participate in this experiment?

"To qualify for this clinical trial, individuals between 18 and 64 years of age with acute pain will be accepted. The study requires 20 participants in total."

Answered by AI

Does this research encompass seniors as study participants?

"Eligible enrollees must be 18 years of age or older and not yet 65."

Answered by AI

Are there still slots available to join this clinical experiment?

"Clinicaltrials.gov states that this investigation is seeking out qualified participants, with the initial posting taking place on September 13th 2022 and most recent editing occurring on October 24th 2022."

Answered by AI

How many individuals have been recruited to partake in this research endeavor?

"Affirmative. According to the clinicaltrials.gov directory, this trial is actively recruiting; it was initially posted on September 13th of 2022 and updated most recently on October 24th of the same year. The research intends to enrol 20 individuals from one location."

Answered by AI
Recent research and studies
~5 spots leftby Nov 2024