Inlyta

advanced Thyroid cancer, Pharmacotherapy, Treatment Naive + 2 more
Treatment
3 FDA approvals
17 Active Studies for Inlyta

What is Inlyta

AxitinibThe Generic name of this drug
Treatment SummaryAxitinib is a medication that works to stop the growth of cancer cells by targeting specific receptors on blood vessels that promote the growth of tumors. It is more powerful than other similar drugs and is available in oral form under the brand name Inlyta®. Axitinib works by blocking angiogenesis, which is the process of creating new blood vessels.
Inlytais the brand name
image of different drug pills on a surface
Inlyta Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Inlyta
Axitinib
2012
4

Approved as Treatment by the FDA

Axitinib, commonly known as Inlyta, is approved by the FDA for 3 uses such as Advanced Renal Cell Carcinoma (aRCC) and Pharmacotherapy .
Advanced Renal Cell Carcinoma (aRCC)
Used to treat Advanced Renal Cell Carcinoma (aRCC) in combination with Avelumab
Pharmacotherapy
Used to treat First Line Chemotherapy in combination with Avelumab
Treatment Naive
Used to treat Treatment Naive in combination with Avelumab

Effectiveness

How Inlyta Affects PatientsAxitinib stops cancer from growing and spreading by preventing new blood vessels from forming in the tumor.
How Inlyta works in the bodyAxitinib stops certain proteins in the body from enabling the growth of new blood vessels.

When to interrupt dosage

The amount of Inlyta is contingent upon the established illness, including Aplastic Anemia, progressed Thyroid malignancy and Aplastic Anemia. The dosage fluctuates as per the method of dispensation specified in the table underneath.
Condition
Dosage
Administration
Advanced Renal Cell Carcinoma (aRCC)
1.0 mg, , 5.0 mg, 7.0 mg, 3.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral
advanced Thyroid cancer
1.0 mg, , 5.0 mg, 7.0 mg, 3.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral
failure of at least one prior systemic therapy
1.0 mg, , 5.0 mg, 7.0 mg, 3.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral
Treatment Naive
1.0 mg, , 5.0 mg, 7.0 mg, 3.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral
Pharmacotherapy
1.0 mg, , 5.0 mg, 7.0 mg, 3.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral

Warnings

There are 20 known major drug interactions with Inlyta.
Common Inlyta Drug Interactions
Drug Name
Risk Level
Description
Bendamustine
Major
The metabolism of Bendamustine can be decreased when combined with Axitinib.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Axitinib.
Copanlisib
Major
The metabolism of Copanlisib can be decreased when combined with Axitinib.
Pomalidomide
Major
The metabolism of Pomalidomide can be decreased when combined with Axitinib.
Revefenacin
Major
Axitinib may decrease the excretion rate of Revefenacin which could result in a higher serum level.
Inlyta Toxicity & Overdose RiskTaking too much axitinib can be dangerous and may cause serious side effects such as high blood pressure, blood clots, bleeding, or a hole in the digestive tract.
image of a doctor in a lab doing drug, clinical research

Inlyta Novel Uses: Which Conditions Have a Clinical Trial Featuring Inlyta?

17 active studies are currently being conducted to determine the efficacy of Inlyta in treating advanced Thyroid Cancer, Aplastic Anemia and other Aplastic Anemias.
Condition
Clinical Trials
Trial Phases
failure of at least one prior systemic therapy
0 Actively Recruiting
Treatment Naive
0 Actively Recruiting
advanced Thyroid cancer
0 Actively Recruiting
Advanced Renal Cell Carcinoma (aRCC)
17 Actively Recruiting
Phase 3, Not Applicable, Phase 1, Phase 2
Pharmacotherapy
0 Actively Recruiting

Inlyta Reviews: What are patients saying about Inlyta?

5Patient Review
8/23/2012
Inlyta for Cancer Involving the Kidney Cells
I've only been on this medication for a short while, so I'm not sure about its long-term effectiveness yet. The main side effect I've noticed is that my voice has become quite hoarse.
3Patient Review
7/8/2013
Inlyta for Cancer Involving the Kidney Cells
My grandfather takes this medication for his cancer, and while it does seem to be helping, the side effects are sometimes really terrible. He never knows if he's going to wake up with diarrhea or not, and the cough meds only make it worse. He's been on this medication for a year now and he's just so sore all the time from all the coughing.
1Patient Review
6/7/2012
Inlyta for Cancer Involving the Kidney Cells
My husband experienced a severe rupture in his intestinal wall after only 2 weeks on Inlyta. He had to have emergency surgery and is now on hospice care.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about inlyta

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Inlyta a targeted therapy?

"Inlyta is a targeted therapy that specifically targets and binds to the vascular endothelial growth factor receptors (VEGFR) that are located on the inside of cancer cells. VEGFR is a protein that is found on the surface of many normal and cancer cells."

Answered by AI

What are the side effects of the medication Inlyta?

"The following are some of the side effects that may occur: nausea, vomiting, loss of appetite, dizziness, tiredness/weakness, weight loss, temporary hair loss, cough, headache, altered sense of taste, hoarseness, constipation, or upset stomach. If you experience any of these side effects, tell your doctor or pharmacist."

Answered by AI

Is Inlyta chemotherapy?

"Inlyta is not a chemotherapy drug. Chemotherapy drugs work by targeting rapidly growing cells throughout the body, which helps to kill cancer cells. However, this also kills many healthy cells in the body."

Answered by AI

What is Inlyta used for?

"Axitinib is a targeted cancer drug that is also known by its brand name Inlyta. Axitinib is a treatment for advanced kidney cancer. Axitinib might also be used as part of a clinical trial for other types of cancer."

Answered by AI

Clinical Trials for Inlyta

Have you considered Inlyta clinical trials? We made a collection of clinical trials featuring Inlyta, we think they might fit your search criteria.
Have you considered Inlyta clinical trials? We made a collection of clinical trials featuring Inlyta, we think they might fit your search criteria.
Have you considered Inlyta clinical trials? We made a collection of clinical trials featuring Inlyta, we think they might fit your search criteria.
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