At-Home vs Clinic-Based Therapy for Advanced Cancer
What You Need to Know Before You Apply
What is the purpose of this trial?
This clinical trial studies the effect of cancer directed therapy given at-home versus in the clinic for patients with cancer that may have spread from where it first started to nearby tissue, lymph nodes, or distant parts of the body (advanced). Currently most drug-related cancer care is conducted in infusion centers or specialty hospitals, where patients spend many hours a day isolated from family, friends, and familiar surroundings. This separation adds to the physical, emotional, social, and financial burden for patients and their families. The logistics and costs of navigating cancer treatments have become a principal contributor to patients' reduced quality of life. It is therefore important to reduce the burden of cancer in the lives of patients and their caregivers, and a vital aspect of this involves moving beyond traditional hospital and clinic-based care and evaluate innovative care delivery models with virtual capabilities. Providing cancer treatment at-home, versus in the clinic, may help reduce psychological and financial distress and increase treatment compliance, especially for marginalized patients and communities.
Do I have to stop taking my current medications for the trial?
The trial does not specify that you need to stop taking your current medications. In fact, it allows for certain standard of care oral drugs and anti-hormonal agents to be taken alongside the trial treatments.
Is at-home therapy for advanced cancer safe for patients?
How is the At-Home vs Clinic-Based Therapy for Advanced Cancer treatment different from other treatments for this condition?
This treatment is unique because it allows advanced cancer patients to receive comprehensive care at home, including physical exams, pain management, chemotherapy, and emotional support, provided by a multidisciplinary team. This approach can reduce the need for hospital visits, decrease pain medication use, and improve quality of life, making it a flexible and patient-centered alternative to traditional hospital-based care.36789
What data supports the effectiveness of the treatment Clinical Encounter, Home Health Encounter for advanced cancer?
Research shows that home-based care for advanced cancer patients can effectively manage pain and improve quality of life. Studies found that home treatment led to decreased need for strong painkillers, reduced hospital stays, and was well-accepted by patients and families, making it a viable alternative to hospital care.2381011
Who Is on the Research Team?
Roxana S. Dronca, MD
Principal Investigator
Mayo Clinic
Are You a Good Fit for This Trial?
This trial is for adults with advanced cancer who live within 35 miles of the clinic, can handle their current chemo well, and plan to continue it for at least 24 weeks. They need Wi-Fi at home and must be able to fill out questionnaires. People needing constant help or on other treatments (except hormone therapy), with severe illnesses, recent serious infections, or unstable heart conditions cannot join.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Initial Treatment
Patients receive at least 1 cycle of their standard of care chemotherapy regimen in the clinic
Randomized Treatment
Patients are randomized to receive chemotherapy either at home or in the clinic
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Clinical Encounter
- Home Health Encounter
Find a Clinic Near You
Who Is Running the Clinical Trial?
Mayo Clinic
Lead Sponsor