Nutritional Intervention for Memory Problems in Overweight Adults
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests how dietary changes might help with memory problems in overweight adults. Participants will either consume a berry fruit powder and follow a low-carbohydrate diet (nutritional ketosis) or take a placebo powder with a higher carbohydrate diet. The goal is to determine if these changes can improve memory issues. It suits those who are overweight and have noticed memory problems but do not have diabetes or other major health issues. As an unphased trial, it provides a unique opportunity to explore innovative dietary approaches to enhance memory health.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications.
Is there any evidence suggesting that this trial's treatments are likely to be safe?
Research has shown that berry-based supplements and foods can improve brain function, including memory. Participants who took these supplements often experienced enhanced memory and brain activity, with no major safety concerns reported.
Similarly, the ketogenic diet, low in carbs and high in fats, has been linked to improved memory in individuals with mild memory issues. This suggests it might be safe, though some studies recommend cautious use. No major harmful side effects have been reported.
Overall, both berry fruit powder and the ketogenic diet appear well-tolerated according to research. No significant negative effects have been consistently reported. However, with any dietary change, individuals should monitor their body's reactions.12345Why are researchers excited about this trial's treatments?
Researchers are excited about these treatments for memory problems in overweight adults because they explore natural and dietary approaches that differ from traditional medications. One treatment uses whole fruit berry powder, which is rich in antioxidants that might protect brain cells and improve memory. The other treatment involves nutritional ketosis, a low carbohydrate diet that could enhance brain function by using ketones as an alternative energy source. Unlike standard treatments that often focus on pharmaceuticals, these interventions offer a more holistic approach, potentially with fewer side effects.
What evidence suggests that this trial's treatments could be effective for memory problems?
Research has shown that eating very few carbohydrates can improve memory in older adults, especially those at risk of memory problems. One study found that reducing carbs, even for a short period, boosted memory. Additionally, foods and supplements made from berries have enhanced brain function and memory. Several studies have found that adding berries to the diet can improve thinking skills. This trial will compare different interventions: one group will receive a combination of berry fruit powder and a low-carb diet, while another group will receive a placebo powder and a higher carbohydrate diet. These findings suggest that combining berry fruit powder with a low-carb diet might help with memory issues in overweight adults.13678
Who Is on the Research Team?
Robert Krikorian, PhD
Principal Investigator
University of Cincinnati Academic Health Center
Are You a Good Fit for This Trial?
This trial is for overweight middle-aged individuals who feel like their memory isn't as good as it used to be. It's not suitable for those with diabetes, age-related memory issues, liver or kidney diseases, neurological or psychiatric conditions, or substance abuse problems.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either whole fruit berry powder with a low carbohydrate diet or placebo powder with a higher carbohydrate diet
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Berry fruit powder OR nutritional ketosis
- Placebo powder OR higher carbohydrate
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Cincinnati
Lead Sponsor