Reviewed by Michael Gill, B. Sc.
25 Kidney Cancer Clinical Trials Near Me
Top Hospitals for Kidney Cancer Clinical Trials
Image of USC / Norris Comprehensive Cancer Center in California.
USC / Norris Comprehensive Cancer Center
Los Angeles
11Active Trials
10All Time Trials for Kidney Cancer
2009First Kidney Cancer Trial
Image of Dana Farber Cancer Institute in Massachusetts.
Dana Farber Cancer Institute
Boston
10Active Trials
11All Time Trials for Kidney Cancer
2014First Kidney Cancer Trial
Top Cities for Kidney Cancer Clinical Trials
Image of Los Angeles in California.
Los Angeles
63Active Trials
USC / Norris Comprehensive Cancer CenterTop Active Site
Kidney Cancer Clinical Trials by Phase of Trial
Phase < 1 Kidney Cancer Clinical Trials
5Active Kidney Cancer Clinical Trials
5Number of Unique Treatments
2Number of Active Locations
NephrectomyDurvalumabMultiparametric Magnetic Resonance ImagingGallium Ga 68-labeled PSMA-11Arm B (nivolumab, bevacizumab, surgery)
Kidney Cancer Clinical Trials by Age Group
18+ Kidney Cancer Clinical Trials
94Active Kidney Cancer Clinical Trials
Cryoablation Assisted Partial NephrectomyOral NKT2152SavolitinibEverolimuseverolimusEntinostatAZD6244Discontinue PD-1/PD-L1-1 inhibitor
Most Recent Kidney Cancer Clinical Trials
Top Treatments for Kidney Cancer Clinical Trials
Treatment Name
Active Kidney Cancer Clinical Trials
All Time Trials for Kidney Cancer
First Recorded Kidney Cancer Trial
Nivolumab
5
22
2014
Ipilimumab
5
12
2014
Pembrolizumab
3
8
2015
Cabozantinib
3
6
2012
Pazopanib Hydrochloride
3
3
2012
Recently Completed Studies with FDA Approved Treatments for Kidney Cancer
Treatment
Year
Sponsor
Perflutren lipid microsphere
2020
UNC Lineberger Comprehensive Cancer Center
Sitravatinib
2017
M.D. Anderson Cancer Center
PDR001
2016
Novartis Pharmaceuticals
INC280
2014
National Cancer Institute (NCI)
Cabozantinib
2012
National Cancer Institute (NCI)

What Are Kidney Cancer Clinical Trials?

This cancer is the growth of abnormal cells in the kidney. A malignant or cancerous cell can rapidly spread to other organs and tissues, and this process is known as metastasis. Kidney cancer patients experience multiple signs and symptoms, like blood in urine, high blood pressure, and flank pain, among other symptoms.

Why Is Kidney Cancer Being Studied Through Clinical Trials?

Around 79,000 kidney cancer cases are diagnosed every year, and an estimated 13,920 individuals don't survive. On average, the patients diagnosed with kidney cancer are around 65.

Around two-thirds of individuals are diagnosed in cases where cancer is only present in the kidney. Among this group, there is a 93% five years survival rate. In cases where cancer has spread to other organs and surrounding tissues, there is a 71% five years survival rate.

This cancer is only treated if it is diagnosed at the early stages.

What Are The Types of Treatments Available For Kidney Cancer?

The treatment of kidney cancer depends on the grade and stage of the tumor, along with the overall health and age of the patient. The treatment options include:

  • Surgery, including Partial nephrectomy and Radical nephrectomy
  • Ablation for patients not suitable for surgery. This includes Cryoablation and Radiofrequency ablation
  • Radiation therapy if the patient has a single kidney and isn’t eligible for surgery
  • Targeted drug therapy
  • Immunotherapy
  • Chemotherapy

What Are Some Recent Breakthrough Clinical Trials For Kidney Cancer?

There have been several landmark studies involving Kidney Cancer in recent years. Some of the most recent studies are:

2022: A clinical trial proved the increase in survival rate among kidney disease patients through immune checkpoint inhibitors. The researchers found an overall survival benefit using FDA-approved nivolumab in comparison to everolimus, which is the standard kidney cancer treatment. While immunotherapy has been proven to have a positive impact on kidney cancer survival but these results have shown drastic survival benefits. This is an opportunity to modify and improve clinical practice and procedures.

2021: Immunotherapy combination has been found to enhance the survival outcome in severe kidney cancer patients. The initial results of the CheckMate -9ER clinical trial phase III showed that the immunotherapy agent mixed with tyrosine kinase inhibitor drastically improved the survival rate and decreased the fatality risk compared to the single agent treatment.

Who Are Some Of The Key Opinion Leaders / Researchers / Institutions Conducting Kidney Cancer Clinical Trials Research?

Kidney Cancer Association: It is a global community empowering and serving kidney cancer patients and leading change through education, research, and advocacy. This association promotes and funds scientific advances through its grant program and annual research symposiums. They are dedicated to becoming the leaders in finding a kidney cancer cure.

National Kidney Foundation: This foundation is among the pioneers of scientific innovation and research for kidney diseases and disorders. They are dedicated to improving the lives of kidney cancer and kidney disease patients through change, education, and action.

About The Author

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 8th, 2021

Last Reviewed: November 23rd, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.