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What is Injectafer
Ferric carboxymaltoseThe Generic name of this drug
Treatment SummaryFerric Carboxymaltose is an FDA-approved medication used to treat iron deficiency. It is a complex of iron and carbohydrates that helps to replace lost iron in the body. The drug was approved by the FDA in 2013.
Injectaferis the brand name
Injectafer Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Injectafer
Ferric carboxymaltose
2013
3
Effectiveness
How Injectafer Affects PatientsTests using positron emission tomography (PET) showed that INJECTAFER was absorbed by red blood cells in patients with iron deficiency at a rate of 91% to 99%. In patients with renal anemia, the absorption rate was lower, ranging from 61% to 84%.
How Injectafer works in the bodyFerric carboxymaltose is a substance that contains iron and a special type of sugar. It releases iron into the body, which helps to replenish iron levels.
When to interrupt dosage
The prescribed dosage of Injectafer is contingent upon the recognized affliction, including Oral cavity, iron and Chronic Kidney Diseases. The measure changes as per the technique of delivery (e.g. Injection, solution or Injection, solution - Intravenous) featured in the table beneath.Condition
Dosage
Administration
Chronic Kidney Diseases
50.0 mg/mL,
Intravenous, , Injection, solution, Injection, solution - Intravenous
iron
50.0 mg/mL,
Intravenous, , Injection, solution, Injection, solution - Intravenous
Oral cavity
50.0 mg/mL,
Intravenous, , Injection, solution, Injection, solution - Intravenous
Iron Deficiency Anemia
50.0 mg/mL,
Intravenous, , Injection, solution, Injection, solution - Intravenous
Warnings
Injectafer ContraindicationsCondition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Ferric Carboxymaltose may interact with Pulse Frequency
Common Injectafer Drug Interactions
Drug Name
Risk Level
Description
Technetium Tc-99m oxidronate
Major
Ferric carboxymaltose can cause a decrease in the absorption of Technetium Tc-99m oxidronate resulting in a reduced serum concentration and potentially a decrease in efficacy.
3-Aza-2,3-Dihydrogeranyl Diphosphate
Minor
Ferric carboxymaltose can cause a decrease in the absorption of 3-Aza-2,3-Dihydrogeranyl Diphosphate resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium Phosphate
Minor
Ferric carboxymaltose can cause a decrease in the absorption of Calcium Phosphate resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium phosphate dihydrate
Minor
Ferric carboxymaltose can cause a decrease in the absorption of Calcium phosphate dihydrate resulting in a reduced serum concentration and potentially a decrease in efficacy.
Dipotassium phosphate
Minor
Ferric carboxymaltose can cause a decrease in the absorption of Dipotassium phosphate resulting in a reduced serum concentration and potentially a decrease in efficacy.
Injectafer Toxicity & Overdose RiskThe most common side effects of taking this drug are nausea, high blood pressure, blushing, low levels of phosphate in the blood, and feeling lightheaded.
Injectafer Novel Uses: Which Conditions Have a Clinical Trial Featuring Injectafer?
Currently, 8 clinical trials are in progress for assessing the effectiveness of Injectafer in providing relief for Oral cavity, Chronic Kidney Diseases and Iron deficiencies.Condition
Clinical Trials
Trial Phases
Chronic Kidney Diseases
3 Actively Recruiting
Phase 3, Phase 2
Oral cavity
0 Actively Recruiting
iron
0 Actively Recruiting
Iron Deficiency Anemia
11 Actively Recruiting
Phase 3, Phase 4, Not Applicable, Phase 2
Injectafer Reviews: What are patients saying about Injectafer?
5Patient Review
7/20/2018 I felt great after using this medication for a few days.
4.7Patient Review
5/12/2022 I had severe anemia from years of heavy periods and the hematologist prescribed Injectafer infusions. I read reviews online and many were negative, so I was a little nervous, but my experience was very smooth and side effect-free. I will go back in six weeks to be sure the infusions have been effective in restoring my hemoglobin/RBC levels.
4Patient Review
3/12/2019 I had a severe headache for three days post-infusion. Tylenol every six hours was the only thing that provided relief. I felt some improvement after just one treatment, but there's still some slight dizziness when standing for too long. Going for my second dose tomorrow. Haven't checked my phosphate levels yet, but intend to ask for this to be done in follow up.
3Patient Review
1/11/2019 A new study has found that this drug severely impairs phosphorous levels in the majority of patients. I ended up in the ER as a result and weeks later my levels are still dangerously low. I would never recommend this drug to anyone.
1.7Patient Review
11/19/2021 Do not take this medication. I had never heard of it before my doctor suggested it, and I should have done more research because the side effects have been awful. After the first infusion, I felt sick to my stomach for a few days. The second one was even worse – I've been having severe migraines, fatigue, anxiety, and heart rate problems for two months now.
1Patient Review
6/12/2021 Please be sure to do your research before deciding on an infusion for iron deficiency. I got severe Hypophosphatemia after my injectafar infusion and still feel horrible a month later. This could take months! Electrolyte imbalance is scary.
1Patient Review
7/2/2018 DO NOT USE THIS DRUG. It has a high chance of causing severe health problems, including muscle weakness and pain.
1Patient Review
5/31/2018 I started having intense spinal pain after only partway through my Fe-infusion of injectafer. Had to go to the hospital for 24 hour observation. Thankfully I was released the next morning.
Patient Q&A Section about injectafer
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.How long does it take Injectafer to work?
"Injectafer treatments improve iron levels quickly and some people notice an improvement in their symptoms within a week. It takes 2 to 3 weeks for the anaemia to be corrected and then you should have better concentration, more energy and have less breathlessness and fatigue."
Answered by AI
What are the side effects of Injectafer?
"The following are potential side effects of the drug: feeling nauseous, having low levels of phosphorus in your blood, having high blood pressure, feeling dizzy, flushing, vomiting, and having a headache."
Answered by AI
How often can Injectafer be given?
"Injectafer is given in two doses, at least 7 days apart."
Answered by AI
What is Injectafer infusion used for?
"Injectafer is a medication used to treat iron deficiency anemia in adults and pediatric patients 1 year of age and older. It is given as an injection into a vein and should only be used if oral iron treatment has not been effective or if the person cannot tolerate oral iron."
Answered by AI