Inderal

Thyroid Crisis, Atrial Fibrillation, Migraine + 23 more
Treatment
5 FDA approvals
20 Active Studies for Inderal

What is Inderal

PropranololThe Generic name of this drug
Treatment SummaryPropranolol is a drug used to treat high blood pressure, made up of two different enantiomers. The S(-)-enantiomer has much higher binding affinity for beta adrenergic receptors. Propranolol was approved by the FDA in 1967 and is widely used to treat many conditions.
Inderalis the brand name
image of different drug pills on a surface
Inderal Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Inderal
Propranolol
1967
471

Approved as Treatment by the FDA

Propranolol, also known as Inderal, is approved by the FDA for 5 uses including Obstructive Hypertrophic Cardiomyopathy and Tremor, Essential .
Obstructive Hypertrophic Cardiomyopathy
Tremor, Essential
Helps manage Tremor, Essential
Essential Tremor
Helps manage Tremor, Essential
Cardiomyopathy, Hypertrophic
Hypertensive disease
Used to treat High Blood Pressure (Hypertension) in combination with Hydrochlorothiazide

Effectiveness

How Inderal Affects PatientsPropranolol is a drug used to treat high blood pressure. It is taken once or twice a day, depending on the situation. If patients stop taking propranolol suddenly, they may experience chest pain or a heart attack.
How Inderal works in the bodyPropranolol is a drug that blocks beta-adrenergic receptors. When blocked, these receptors cause the blood vessels to narrow and stop the growth of new blood vessels. It also helps stop the body from creating certain hormones that affect blood pressure.

When to interrupt dosage

The measure of Inderal is contingent upon the identified disease, including Catecholamines, Hypertensive sickness and Hemangiomas. The amount of dosage is contingent on the administration procedure (e.g. Solution - Oral or Capsule, extended release - Oral) delineated in the table beneath.
Condition
Dosage
Administration
Heart Attack
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Adrenergic Alpha-Antagonists
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Tachyarrhythmia caused by Digitalis intoxication
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Psychomotor Agitation
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Tremor
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Thyrotoxicosis
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Chest Pain
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Supraventricular Arrhythmias
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Hemangioma
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Cardiomyopathy, Hypertrophic
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Proliferating Infantile Hemangioma
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Hypertensive disease
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Performance Anxiety
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Pheochromocytoma
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Ventricular Tachycardia
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Migraine
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Gastroesophageal variceal hemorrhage prophylaxis
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Catecholamines
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Migraine Disorders
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Atrial Fibrillation
, 1.0 mg/mL, 60.0 mg, 80.0 mg, 120.0 mg, 160.0 mg, 40.0 mg, 10.0 mg, 20.0 mg, 50.0 mg, 0.1 mg, 4.28 mg/mL, 4.0 mg/mg, 2.0 mg/mg, 20.0 mg/mL, 40.0 mg/mL, 3.75 mg/mL
, Intravenous, Injection, Injection - Intravenous, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, Tablet - Oral, Injection, solution - Intravenous, Injection, solution, Solution, Solution - Oral, Solution - Intravenous, Liquid, Liquid - Intravenous, Capsule, gelatin coated, Capsule, gelatin coated - Oral

Warnings

Inderal Contraindications
Condition
Risk Level
Notes
Heart Decompensation
Do Not Combine
Bronchial Spasm
Do Not Combine
Asthma
Do Not Combine
Infants Weighing <2kg
Do Not Combine
Low Blood Pressure
Do Not Combine
Sick Sinus Syndrome
Do Not Combine
Asthma
Do Not Combine
Pheochromocytoma
Do Not Combine
Atrioventricular Block
Do Not Combine
Slow Heart Rate
Do Not Combine
Shock, Cardiogenic
Do Not Combine
Heart Decompensation
Do Not Combine
Prematurity
Do Not Combine
Sinus Bradycardia
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Propranolol may interact with Pulse Frequency
There are 20 known major drug interactions with Inderal.
Common Inderal Drug Interactions
Drug Name
Risk Level
Description
4-Bromo-2,5-dimethoxyphenethylamine
Major
The therapeutic efficacy of 4-Bromo-2,5-dimethoxyphenethylamine can be decreased when used in combination with Propranolol.
4-Methoxyamphetamine
Major
The therapeutic efficacy of 4-Methoxyamphetamine can be decreased when used in combination with Propranolol.
Abediterol
Major
Propranolol may decrease the bronchodilatory activities of Abediterol.
Adrafinil
Major
The therapeutic efficacy of Adrafinil can be decreased when used in combination with Propranolol.
Agrostis gigantea pollen
Major
The risk of a hypersensitivity reaction to Agrostis gigantea pollen is increased when it is combined with Propranolol.
Inderal Toxicity & Overdose RiskOverdosing on propranolol can cause low blood pressure, seizures, restlessness, and difficulty sleeping. Those with asthma may experience difficulty breathing. If a patient overdoses on propranolol, their vital signs and mental status should be monitored, and low blood pressure should be treated with intravenous fluids. To treat bradycardia, atropine or isoproterenol and aminophylline can be used. Glucagon is recommended if intravenous fluids are not effective, followed by catecholamines. Dialysis will not be effective since propranolol is highly protein bound.
image of a doctor in a lab doing drug, clinical research

Inderal Novel Uses: Which Conditions Have a Clinical Trial Featuring Inderal?

249 active studies are presently analyzing the potential of Inderal to mitigate Migraine, Catecholamine-related ailments and Hypertensive disease.
Condition
Clinical Trials
Trial Phases
Atrial Fibrillation
96 Actively Recruiting
Not Applicable, Phase 2, Phase 4, Phase 1, Phase 3, Early Phase 1
Heart Attack
26 Actively Recruiting
Not Applicable, Phase 4, Phase 1, Phase 2, Early Phase 1, Phase 3
Coronary Artery Disease
1 Actively Recruiting
Not Applicable
Chest Pain
2 Actively Recruiting
Not Applicable, Phase 2, Phase 3
Adrenergic Alpha-Antagonists
0 Actively Recruiting
Migraine
52 Actively Recruiting
Phase 4, Not Applicable, Phase 2, Phase 1, Phase 3, Early Phase 1
Hemangioma
0 Actively Recruiting
Gastroesophageal variceal hemorrhage prophylaxis
0 Actively Recruiting
Migraine Disorders
1 Actively Recruiting
Phase 3
Catecholamines
0 Actively Recruiting
Thyroid Crisis
0 Actively Recruiting
Hypertensive disease
23 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3
Pheochromocytoma
0 Actively Recruiting
Thyrotoxicosis
0 Actively Recruiting
Cardiovascular Mortality
0 Actively Recruiting
Myocardial Infarction
0 Actively Recruiting
Tremor
0 Actively Recruiting
Cardiomyopathy, Hypertrophic
0 Actively Recruiting
Proliferating Infantile Hemangioma
0 Actively Recruiting
Psychomotor Agitation
0 Actively Recruiting

Inderal Reviews: What are patients saying about Inderal?

5Patient Review
1/9/2015
Inderal for Essential Tremor
So far, I'm really pleased with this medication. I was on Primidone for three years to treat my tremors, but my doctor told me to add Inderal (which is really just the generic version) to the mix. So far, it's been working great and I haven't had any tremors. The only downside is that I have to be careful about gaining weight, but I'm hoping to conquer that at the gym.
5Patient Review
3/20/2014
Inderal for Migraine Prevention
Inderal has really cut down on the frequency and severity of my migraines. I'm willing to put up with a little fatigue and weight gain in order to have fewer migraines.
5Patient Review
3/23/2014
Inderal for Anxious
Inderal has been an absolute game-changer for me and my panic attacks. They've significantly decreased since starting the medication, and I haven't experienced any negative side effects (aside from feeling tired occasionally).
5Patient Review
3/26/2019
Inderal for Migraine Prevention
This medicine has been a total game-changer for me. I used to suffer from 1-2 migraines per week, and they were severe enough that I would have to spend 24 hours in a dark room just trying to recover. But since taking Inderal, my migraines have gone down to once a month or even longer intervals. It's really changed my life for the better.
5Patient Review
3/4/2019
Inderal for Migraine Prevention
I've been taking this since 1999 and it's by far the best migraine medication I've ever tried. I used to get migraines almost every week that would confine me to a dark room in agony, but since taking this medication I've only had them sporadically and they're much easier to live with.
View All Reviews
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Patient Q&A Section about inderal

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Inderal a sleeping pill?

"Inderal 10 MG Tablet does not have a known effect on sleep. It works by reducing blood pressure by blocking the beta2 receptors present on the heart, which are responsible for increased blood pressure. It also relaxes the blood vessels, which enhances proper blood flow in the body."

Answered by AI

Is Inderal used for anxiety?

"A beta-blocker such as propranolol may be prescribed by a doctor to help relieve a person's anxiety symptoms during stressful situations, like going to a party or giving a speech."

Answered by AI

What are the most common side effects of propranolol?

"Propranolol's primary side effects are feelings of dizziness or fatigue, cold hands and feet, difficulty sleeping, and nightmares. These effects are generally mild and of limited duration."

Answered by AI

What is the side effects of Inderal?

"You may feel dizzy, lightheaded, or tired as your body gets used to the medication. Other possible side effects include nausea or vomiting, stomach pain, vision changes, trouble sleeping, and strange dreams. If you experience any of these side effects for an extended period of time, or if they get worse, let your doctor or pharmacist know."

Answered by AI

Clinical Trials for Inderal

Have you considered Inderal clinical trials? We made a collection of clinical trials featuring Inderal, we think they might fit your search criteria.
Have you considered Inderal clinical trials? We made a collection of clinical trials featuring Inderal, we think they might fit your search criteria.
Have you considered Inderal clinical trials? We made a collection of clinical trials featuring Inderal, we think they might fit your search criteria.