Iloperidone

Schizophrenia
Treatment
1 FDA approval
20 Active Studies for Iloperidone

What is Iloperidone

IloperidoneThe Generic name of this drug
Treatment SummaryIloperidone is an antipsychotic drug used to treat schizophrenia. It was developed by Hoechst Marion Roussel Inc. until May 1996 and was then passed on to Titan Pharmaceuticals. In 1998, Novartis received the worldwide rights for its development, manufacturing, and marketing. Vanda Pharmaceuticals then took over in 2004 and the FDA approved it in 2009.
Fanaptis the brand name
image of different drug pills on a surface
Iloperidone Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Fanapt
Iloperidone
2009
37

Approved as Treatment by the FDA

Iloperidone, commonly known as Fanapt, is approved by the FDA for 1 uses including Schizophrenia .
Schizophrenia
Helps manage Schizophrenia

Effectiveness

How Iloperidone Affects PatientsIloperidone has a strong connection to certain parts of the brain that help with schizophrenia and cognitive function. It is particularly connected to dopamine D2, α adrenergic, serotonin 5-HT2a, dopamine 3, dopamine D4, serotonin 5-HT6 and 5-HT7, norepinephrine NEα1, serotonin 5-HT1A, dopamine D1, and histamine H1 receptors.
How Iloperidone works in the bodyIloperidone works by blocking the effects of two different types of brain receptors, dopamine D2 and 5-HT2A, which helps reduce symptoms associated with mental illnesses.

When to interrupt dosage

The proposed dosage of Iloperidone is contingent upon the diagnosed condition. The amount of dosage is contingent upon the delivery technique (e.g. Kit or Tablet - Oral), as demonstrated in the following table.
Condition
Dosage
Administration
Schizophrenia
1.0 mg, 2.0 mg, 4.0 mg, 6.0 mg, 8.0 mg, 10.0 mg, 12.0 mg, , 13.0 mg
, Oral, Tablet, Tablet - Oral, Kit - Oral, Kit

Warnings

There are 20 known major drug interactions with Iloperidone.
Common Iloperidone Drug Interactions
Drug Name
Risk Level
Description
Alfuzosin
Major
Iloperidone may increase the hypotensive activities of Alfuzosin.
Amisulpride
Major
Iloperidone may increase the antipsychotic activities of Amisulpride.
Aripiprazole lauroxil
Major
Iloperidone may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Aripiprazole lauroxil.
Artemether
Major
The risk or severity of QTc prolongation can be increased when Iloperidone is combined with Artemether.
Asenapine
Major
Iloperidone may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Asenapine.
Iloperidone Toxicity & Overdose RiskSide effects of taking this drug that are seen in five percent or more of patients, and are twice as likely as with a placebo, include dizziness, dry mouth, fatigue, stuffy nose, low blood pressure when standing up, sleepiness, a fast heartbeat, and weight gain.
image of a doctor in a lab doing drug, clinical research

Iloperidone Novel Uses: Which Conditions Have a Clinical Trial Featuring Iloperidone?

170 clinical trials are in progress to assess the suitability of Iloperidone in treating Schizophrenia.
Condition
Clinical Trials
Trial Phases
Schizophrenia
175 Actively Recruiting
Not Applicable, Phase 3, Phase 2, Early Phase 1, Phase 4, Phase 1

Iloperidone Reviews: What are patients saying about Iloperidone?

4Patient Review
12/5/2011
Iloperidone for Schizophrenia
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about iloperidone

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is iloperidone a second generation antipsychotic?

"Iloperidone is an antipsychotic agent indicated for the acute treatment of schizophrenia in adults. It has been evaluated in several double-blind placebo-controlled clinical trials."

Answered by AI

What kind of drug is iloperidone?

"Iloperidone is a medication used to manage the symptoms of schizophrenia. It is classified as an atypical antipsychotic medication."

Answered by AI

What are the side effects of iloperidone?

"Dizziness or lightheadedness may occur, especially when rising from a lying or sitting position. To avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up.

You may experience drowsiness, dizziness, lightheadedness, dry mouth, tiredness, a stuffy nose, and weight gain. If you experience any of these effects that persist or worsen, tell your doctor or pharmacist. This medication may cause a serious drop in blood pressure, especially when starting or increasing the dose. You may experience dizziness or lightheadedness, which may be worse when rising from a lying or sitting position. To avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up."

Answered by AI

What is iloperidone used for?

"This drug is used to treat the symptoms of psychotic disorders such as schizophrenia. Do not use it to treatbehavioral problems in patients who are elderly and have dementia. A doctor's prescription is required to purchase this medicine."

Answered by AI

Clinical Trials for Iloperidone

Have you considered Iloperidone clinical trials? We made a collection of clinical trials featuring Iloperidone, we think they might fit your search criteria.
Have you considered Iloperidone clinical trials? We made a collection of clinical trials featuring Iloperidone, we think they might fit your search criteria.
Have you considered Iloperidone clinical trials? We made a collection of clinical trials featuring Iloperidone, we think they might fit your search criteria.
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top