Fortical

Hypercalcemia, Osteoporotic Fractures, Osteoporosis + 5 more
Treatment
20 Active Studies for Fortical

What is Fortical

Salmon calcitoninThe Generic name of this drug
Treatment SummaryNasal spray containing a 32-amino acid chain, a type of protein.
Miacalcinis the brand name
image of different drug pills on a surface
Fortical Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Miacalcin
Salmon calcitonin
1986
16

Effectiveness

How Fortical Affects PatientsCalcitonin helps increase bone mass and reduce the amount of calcium in the blood. It also increases the amount of certain minerals that the kidneys flush out, like calcium, phosphate, sodium, magnesium, and potassium. This results in more water, sodium, potassium, and chloride being released into the intestine.
How Fortical works in the bodyCalcitonin helps to increase bone density by attaching itself to cells in your bones. This triggers a reaction that produces enzymes that help your body keep more calcium. It also helps your bones by activating a pathway that helps retain calcium.

When to interrupt dosage

The proposed dose of Fortical is contingent upon the ascertained condition, such as Osteoporosis, Postmenopause and Hypercalcemia. The measure of dosage may vary, depending on the technique of delivery (e.g. Injection, solution or Intramuscular; Subcutaneous) featured in the table beneath.
Condition
Dosage
Administration
Immobilization
, 200.0 [iU], 2200.0 [iU]/mL, 20000.0 [iU]/mL, 200.0 [iU]/mL, 100.0 [iU], 200.0 [USP'U]/mL, 200.0 units/mL, 200.0 units/pump actuation, 100.0 units/mL, 200.0 units/spray
, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Intramuscular; Subcutaneous, Solution, Solution - Intramuscular; Subcutaneous, Liquid, Liquid - Intramuscular; Subcutaneous, Spray - Nasal, Spray, Solution - Nasal, Liquid - Nasal, Liquid - Intramuscular; Intravenous; Subcutaneous, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Subcutaneous
Postmenopause
, 200.0 [iU], 2200.0 [iU]/mL, 20000.0 [iU]/mL, 200.0 [iU]/mL, 100.0 [iU], 200.0 [USP'U]/mL, 200.0 units/mL, 200.0 units/pump actuation, 100.0 units/mL, 200.0 units/spray
, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Intramuscular; Subcutaneous, Solution, Solution - Intramuscular; Subcutaneous, Liquid, Liquid - Intramuscular; Subcutaneous, Spray - Nasal, Spray, Solution - Nasal, Liquid - Nasal, Liquid - Intramuscular; Intravenous; Subcutaneous, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Subcutaneous
Paget’s Disease
, 200.0 [iU], 2200.0 [iU]/mL, 20000.0 [iU]/mL, 200.0 [iU]/mL, 100.0 [iU], 200.0 [USP'U]/mL, 200.0 units/mL, 200.0 units/pump actuation, 100.0 units/mL, 200.0 units/spray
, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Intramuscular; Subcutaneous, Solution, Solution - Intramuscular; Subcutaneous, Liquid, Liquid - Intramuscular; Subcutaneous, Spray - Nasal, Spray, Solution - Nasal, Liquid - Nasal, Liquid - Intramuscular; Intravenous; Subcutaneous, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Subcutaneous
Hypercalcemia
, 200.0 [iU], 2200.0 [iU]/mL, 20000.0 [iU]/mL, 200.0 [iU]/mL, 100.0 [iU], 200.0 [USP'U]/mL, 200.0 units/mL, 200.0 units/pump actuation, 100.0 units/mL, 200.0 units/spray
, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Intramuscular; Subcutaneous, Solution, Solution - Intramuscular; Subcutaneous, Liquid, Liquid - Intramuscular; Subcutaneous, Spray - Nasal, Spray, Solution - Nasal, Liquid - Nasal, Liquid - Intramuscular; Intravenous; Subcutaneous, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Subcutaneous
Osteoporotic Fractures
, 200.0 [iU], 2200.0 [iU]/mL, 20000.0 [iU]/mL, 200.0 [iU]/mL, 100.0 [iU], 200.0 [USP'U]/mL, 200.0 units/mL, 200.0 units/pump actuation, 100.0 units/mL, 200.0 units/spray
, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Intramuscular; Subcutaneous, Solution, Solution - Intramuscular; Subcutaneous, Liquid, Liquid - Intramuscular; Subcutaneous, Spray - Nasal, Spray, Solution - Nasal, Liquid - Nasal, Liquid - Intramuscular; Intravenous; Subcutaneous, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Subcutaneous
Osteoporosis
, 200.0 [iU], 2200.0 [iU]/mL, 20000.0 [iU]/mL, 200.0 [iU]/mL, 100.0 [iU], 200.0 [USP'U]/mL, 200.0 units/mL, 200.0 units/pump actuation, 100.0 units/mL, 200.0 units/spray
, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Intramuscular; Subcutaneous, Solution, Solution - Intramuscular; Subcutaneous, Liquid, Liquid - Intramuscular; Subcutaneous, Spray - Nasal, Spray, Solution - Nasal, Liquid - Nasal, Liquid - Intramuscular; Intravenous; Subcutaneous, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Subcutaneous
Osteitis Deformans
, 200.0 [iU], 2200.0 [iU]/mL, 20000.0 [iU]/mL, 200.0 [iU]/mL, 100.0 [iU], 200.0 [USP'U]/mL, 200.0 units/mL, 200.0 units/pump actuation, 100.0 units/mL, 200.0 units/spray
, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Intramuscular; Subcutaneous, Solution, Solution - Intramuscular; Subcutaneous, Liquid, Liquid - Intramuscular; Subcutaneous, Spray - Nasal, Spray, Solution - Nasal, Liquid - Nasal, Liquid - Intramuscular; Intravenous; Subcutaneous, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Subcutaneous
Therapeutic procedure
, 200.0 [iU], 2200.0 [iU]/mL, 20000.0 [iU]/mL, 200.0 [iU]/mL, 100.0 [iU], 200.0 [USP'U]/mL, 200.0 units/mL, 200.0 units/pump actuation, 100.0 units/mL, 200.0 units/spray
, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Intramuscular; Subcutaneous, Solution, Solution - Intramuscular; Subcutaneous, Liquid, Liquid - Intramuscular; Subcutaneous, Spray - Nasal, Spray, Solution - Nasal, Liquid - Nasal, Liquid - Intramuscular; Intravenous; Subcutaneous, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Subcutaneous

Warnings

There are 20 known major drug interactions with Fortical.
Common Fortical Drug Interactions
Drug Name
Risk Level
Description
Abacavir
Minor
Salmon calcitonin may decrease the excretion rate of Abacavir which could result in a higher serum level.
Acetaminophen
Minor
Salmon calcitonin may decrease the excretion rate of Acetaminophen which could result in a higher serum level.
Acetohexamide
Minor
The therapeutic efficacy of Acetohexamide can be decreased when used in combination with Salmon calcitonin.
Aclidinium
Minor
Salmon calcitonin may decrease the excretion rate of Aclidinium which could result in a higher serum level.
Acrivastine
Minor
Salmon calcitonin may decrease the excretion rate of Acrivastine which could result in a higher serum level.
Fortical Toxicity & Overdose RiskPregnant women, nursing mothers, and those with a history of allergies should be careful when taking salmon calcitonin, as it may reduce fetal weight in animals. Allergy reactions may also occur, such as difficulty breathing, swelling of the tongue or throat, and anaphylaxis. The manufacturer has reported an increased risk (from 0.7% to 2.4%) of cancer when taking salmon calcitonin orally compared to placebo. Other side effects may include nausea, rhinitis, headaches, and back pain.

Fortical Novel Uses: Which Conditions Have a Clinical Trial Featuring Fortical?

57 active trials are being conducted to assess the potential of Fortical to facilitate Therapeutic procedures, address Postmenopause symptoms and treat Osteitis Deformans.
Condition
Clinical Trials
Trial Phases
Hypercalcemia
1 Actively Recruiting
Phase 4
Immobilization
0 Actively Recruiting
Paget’s Disease
0 Actively Recruiting
Osteoporotic Fractures
3 Actively Recruiting
Phase 4, Not Applicable
Osteoporosis
34 Actively Recruiting
Not Applicable, Phase 2, Phase 4, Phase 1, Phase 3
Osteitis Deformans
0 Actively Recruiting
Postmenopause
8 Actively Recruiting
Phase 2, Not Applicable, Phase 1
Therapeutic procedure
0 Actively Recruiting

Fortical Reviews: What are patients saying about Fortical?

5Patient Review
12/14/2010
Fortical for Decreased Bone Mass Following Menopause
This medication is prescribed for bone loss prior to menopause. It's great because it will actually grow back! After using it for two years and taking 1200mg of calcium daily, 50% of my bone loss had grown back. Another generic brand, calcitonin spray; the sprayer jams after only 2 weeks of usage.
5Patient Review
5/28/2011
Fortical for Decreased Bone Mass Following Menopause
This was simple to use and the only downside was a bit of nose irritation.
4Patient Review
2/14/2009
Fortical for Decreased Bone Mass Following Menopause
I've only been using this medication for a week or so, but I'm already seeing some benefits. My nose is less runny and there's less crusting.
3.3Patient Review
9/21/2007
Fortical for Decreased Bone Mass Following Menopause
3Patient Review
2/23/2010
Fortical for Decreased Bone Mass Following Menopause
I took Fortical a total of four times and now experience burning sensations when urinating. As a result, I have discontinued use of the medication.
View All Reviews
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Patient Q&A Section about fortical

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is Miacalcin nasal spray used for?

"The text is saying that calcitonin is a nasal spray and injection used to treat osteoporosis in postmenopausal females, Paget's disease of bone, and high calcium, but it is not the best option."

Answered by AI

What is fortical pills used for?

"This drug is used to manage osteoporosis in women who are at least 5 years post-menopausal. Calcitonin helps to prevent bone loss and maintain strong bones, which decreases the likelihood of fractures."

Answered by AI

How does calcitonin nasal spray work?

"The purpose of calcitonin salmon nasal spray is to reduce the rate at which bones are broken down by cells called osteoclasts, and to encourage cells called osteoblasts to rebuild bones. This increases the density of bone in the lower spine."

Answered by AI

How long can you take calcitonin?

"Calcitonin helps to prevent bone loss when a person is immobilized for a short period of time following an osteoporotic fracture."

Answered by AI

Clinical Trials for Fortical

Have you considered Fortical clinical trials? We made a collection of clinical trials featuring Fortical, we think they might fit your search criteria.
Have you considered Fortical clinical trials? We made a collection of clinical trials featuring Fortical, we think they might fit your search criteria.
Have you considered Fortical clinical trials? We made a collection of clinical trials featuring Fortical, we think they might fit your search criteria.
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