Fml Forte

Swelling, Inflammation, Anterior chamber inflammation + 5 more
Treatment
1 FDA approval
20 Active Studies for Fml Forte

What is Fml Forte

FluorometholoneThe Generic name of this drug
Treatment SummaryPrednisolone is a steroid medication used to reduce inflammation in the eyes and on the skin. It is usually applied in the form of eye drops for eye conditions and to treat skin disorders.
FMLis the brand name
image of different drug pills on a surface
Fml Forte Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
FML
Fluorometholone
1972
11

Approved as Treatment by the FDA

Fluorometholone, also called FML, is approved by the FDA for 1 uses such as Ocular Inflammation .
Ocular Inflammation

Effectiveness

How Fml Forte Affects PatientsCorticosteroids like fluorometholone help to reduce inflammation. They can also slow down the healing process by preventing swelling, blood clotting, widening of blood vessels, white blood cell movement, new blood vessel growth, collagen production, and scarring.
How Fml Forte works in the bodyOcular corticosteroids are thought to work by blocking inflammation-causing molecules from being produced. They do this by stopping the release of arachidonic acid, which is the precursor molecule for these inflammation-causing molecules. Corticosteroids also bind to the cell's glucocorticoid receptor, which then moves into the nucleus of the cell. There, it binds to target genes, causing them to increase expression and ultimately blocking inflammation.

When to interrupt dosage

The dosage of Fml Forte is contingent upon the diagnosed condition, such as Anterior chamber inflammation, eye surgery and Ocular Inflammation. The quantity likewise fluctuates as per the approach of delivery (e.g. Ointment - Ophthalmic or Suspension - Ophthalmic) specified in the table below.
Condition
Dosage
Administration
eye surgery
0.001 mg/mg, , 1.0 mg/mL, 2.5 mg/mL, 0.1 %, 0.25 %, 0.001 mL/mL
, Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Suspension, Suspension - Ophthalmic
Vascular injection
0.001 mg/mg, , 1.0 mg/mL, 2.5 mg/mL, 0.1 %, 0.25 %, 0.001 mL/mL
, Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Suspension, Suspension - Ophthalmic
Swelling
0.001 mg/mg, , 1.0 mg/mL, 2.5 mg/mL, 0.1 %, 0.25 %, 0.001 mL/mL
, Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Suspension, Suspension - Ophthalmic
Inflammation
0.001 mg/mg, , 1.0 mg/mL, 2.5 mg/mL, 0.1 %, 0.25 %, 0.001 mL/mL
, Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Suspension, Suspension - Ophthalmic
Allergic Conjunctivitis (AC)
0.001 mg/mg, , 1.0 mg/mL, 2.5 mg/mL, 0.1 %, 0.25 %, 0.001 mL/mL
, Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Suspension, Suspension - Ophthalmic
Anterior chamber inflammation
0.001 mg/mg, , 1.0 mg/mL, 2.5 mg/mL, 0.1 %, 0.25 %, 0.001 mL/mL
, Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Suspension, Suspension - Ophthalmic
Ocular Inflammation
0.001 mg/mg, , 1.0 mg/mL, 2.5 mg/mL, 0.1 %, 0.25 %, 0.001 mL/mL
, Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Suspension, Suspension - Ophthalmic
ocular bacterial infections
0.001 mg/mg, , 1.0 mg/mL, 2.5 mg/mL, 0.1 %, 0.25 %, 0.001 mL/mL
, Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Suspension, Suspension - Ophthalmic

Warnings

Fml Forte has five contraindications, so it should not be taken when dealing with the conditions listed in the below table.Fml Forte Contraindications
Condition
Risk Level
Notes
Eye
Do Not Combine
conjunctiva
Do Not Combine
conjunctiva
Do Not Combine
viral disease of cornea and conjunctiva caused by Varicella Zoster
Do Not Combine
Eye Infections, Fungal
Do Not Combine
There are 20 known major drug interactions with Fml Forte.
Common Fml Forte Drug Interactions
Drug Name
Risk Level
Description
2-Methoxyethanol
Major
The risk or severity of adverse effects can be increased when Fluorometholone is combined with 2-Methoxyethanol.
9-(N-methyl-L-isoleucine)-cyclosporin A
Major
The risk or severity of adverse effects can be increased when Fluorometholone is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Abatacept
Major
The risk or severity of adverse effects can be increased when Fluorometholone is combined with Abatacept.
Abetimus
Major
The risk or severity of adverse effects can be increased when Fluorometholone is combined with Abetimus.
Acteoside
Major
The risk or severity of adverse effects can be increased when Fluorometholone is combined with Acteoside.
Fml Forte Toxicity & Overdose RiskPossible side effects of corticosteroid use include inflammation of the eye, eye ulcers, dilated pupils, redness of the eyes, difficulty focusing, and drooping eyelids. In tests, the lowest dose of corticosteroids that caused toxicity in rats was 234mg/kg.
image of a doctor in a lab doing drug, clinical research

Fml Forte Novel Uses: Which Conditions Have a Clinical Trial Featuring Fml Forte?

A total of 189 active studies are presently exploring the potential of Fml Forte to alleviate Inflammation, Swelling and Ocular Inflammatory conditions.
Condition
Clinical Trials
Trial Phases
Inflammation
172 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Early Phase 1, Phase 3, Phase 4
Swelling
0 Actively Recruiting
Anterior chamber inflammation
0 Actively Recruiting
eye surgery
0 Actively Recruiting
Allergic Conjunctivitis (AC)
1 Actively Recruiting
Phase 2
Ocular Inflammation
3 Actively Recruiting
Phase 2, Phase 4, Phase 3
ocular bacterial infections
0 Actively Recruiting
Vascular injection
0 Actively Recruiting

Fml Forte Reviews: What are patients saying about Fml Forte?

5Patient Review
5/1/2016
Fml Forte for Inflammation of the Eye Following Surgery
I had a DALK (Depp Anterior Lamellar Keratoplasty) done to one of my eyes. FML was prescribed along with Refresh Liquigel. I have never had any issues with it. It helped me through the most painful period right after surgery and I was asked to use it for 6 months. My vision has drastically improved, which means that I didn't have any negative effects due to this drug.
5Patient Review
11/4/2014
Fml Forte for Allergic Conjunctivitis
I followed the instructions and used these drops four times a day for a month after my eye surgery. They didn't burn, which was great. I don't know if the treatment is supposed to last a month though, since I had severe myopia before (which is stated in the precautions). Either way, I'm going to stop early because my eyes feel and look great.
3Patient Review
4/27/2014
Fml Forte for Inflammation of the Eye Following Surgery
I was originally prescribed this medication for excessive tearing, which I believe was caused by tear duct plugs that were inserted by the same doctor. However, after doing some research on the long-term complications and lack of results, I decided to stop taking the medication.
2.3Patient Review
12/7/2008
Fml Forte for Severe Inflammation of the Cornea with Rosacea Involvement
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Patient Q&A Section about fml forte

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is FML Forte used for?

"This medication is used to relieve symptoms of eye conditions caused by inflammation or injury, such as swelling, redness, and itching. It belongs to a class of drugs known as corticosteroids."

Answered by AI

Is FML Forte a steroid?

"This is a medication that is used to treat swelling in the eyes that is caused by infections, injury, surgery, or other conditions."

Answered by AI

Why we use FML eye drops?

"FML® eye drops are for treating pain, swelling and redness of the eye caused by inflammation. The active ingredient in FML® eye drops, fluorometholone, works by inhibiting the inflammation caused by certain irritations in the eye. You can only get FML® eye drops with a doctor's prescription from pharmacies."

Answered by AI

Is fluorometholone the same as FML Forte?

"-FML FORTE is a sterile ophthalmic suspension that is a topical anti-inflammatory product for use on the eyes. -The chemical name for FML FORTE is Fluorometholone: 9-Fluoro-11β, 17-dihydroxy-6α-methylpregna-1,4-diene-3,20-dione."

Answered by AI

Clinical Trials for Fml Forte

Have you considered Fml Forte clinical trials? We made a collection of clinical trials featuring Fml Forte, we think they might fit your search criteria.
Have you considered Fml Forte clinical trials? We made a collection of clinical trials featuring Fml Forte, we think they might fit your search criteria.
Have you considered Fml Forte clinical trials? We made a collection of clinical trials featuring Fml Forte, we think they might fit your search criteria.
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