Fesoterodine Fumarate

Overactive Bladder Syndrome, Neurogenic Detrusor Overactivity, Obesity
Treatment
20 Active Studies for Fesoterodine Fumarate

What is Fesoterodine Fumarate

FesoterodineThe Generic name of this drug
Treatment SummaryFesoterodine is a medication used to treat the symptoms of an overactive bladder, such as frequent urination and urge urinary incontinence.
Toviazis the brand name
image of different drug pills on a surface
Fesoterodine Fumarate Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Toviaz
Fesoterodine
2008
29

Effectiveness

How Fesoterodine Fumarate Affects PatientsFesoteridine is broken down into 5-hydroxymethyl tolterodine (5-HMT) by the body. 5-HMT has the effect of blocking certain receptors (muscarinic) that cause increased bladder contractions and salivation. This reduces the pressure in the bladder and the urge to urinate.
How Fesoterodine Fumarate works in the bodyFesoterodine stops the muscles in your bladder from contracting. This reduces pressure in the bladder and limits how much can be emptied at once.

When to interrupt dosage

The proposed dose of Fesoterodine Fumarate is contingent upon the diagnosed state. The measure of dosage fluctuates, relative to the technique of delivery (e.g. Tablet, extended release or Tablet, film coated, extended release) noted in the table below.
Condition
Dosage
Administration
Overactive Bladder Syndrome
, 4.0 mg, 8.0 mg
, Oral, Tablet, film coated, extended release - Oral, Tablet, film coated, extended release, Tablet, extended release, Tablet, extended release - Oral
Neurogenic Detrusor Overactivity
, 4.0 mg, 8.0 mg
, Oral, Tablet, film coated, extended release - Oral, Tablet, film coated, extended release, Tablet, extended release, Tablet, extended release - Oral
Obesity
, 4.0 mg, 8.0 mg
, Oral, Tablet, film coated, extended release - Oral, Tablet, film coated, extended release, Tablet, extended release, Tablet, extended release - Oral

Warnings

Fesoterodine Fumarate has four contraindications, so it should not be used when any of the conditions in the table below are present.Fesoterodine Fumarate Contraindications
Condition
Risk Level
Notes
uncontrolled narrow-angle glaucoma
Do Not Combine
Gastric Retention
Do Not Combine
Urinary Retention
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Fesoterodine may interact with Pulse Frequency
There are 20 known major drug interactions with Fesoterodine Fumarate.
Common Fesoterodine Fumarate Drug Interactions
Drug Name
Risk Level
Description
Aclidinium
Major
The risk or severity of adverse effects can be increased when Fesoterodine is combined with Aclidinium.
Amitriptyline
Major
The metabolism of Amitriptyline can be decreased when combined with Fesoterodine.
Amoxapine
Major
The metabolism of Amoxapine can be decreased when combined with Fesoterodine.
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Fesoterodine.
Cimetropium
Major
The risk or severity of adverse effects can be increased when Fesoterodine is combined with Cimetropium.
Fesoterodine Fumarate Toxicity & Overdose RiskTests have shown that it takes 681 milligrams per kilogram of body weight to be toxic to rats when taken orally, and 316 milligrams per kilogram of body weight to be toxic to mice when taken orally. For rats and mice, 10 milligrams per kilogram of body weight is the highest dose tested without any observed adverse effects when taken intravenously.
image of a doctor in a lab doing drug, clinical research

Fesoterodine Fumarate Novel Uses: Which Conditions Have a Clinical Trial Featuring Fesoterodine Fumarate?

32 active trials are being conducted to assess the capacity of Fesoterodine Fumarate to alleviate symptoms of Overactive Bladder Syndrome.
Condition
Clinical Trials
Trial Phases
Neurogenic Detrusor Overactivity
3 Actively Recruiting
Phase 2, Phase 3, Phase 1
Obesity
0 Actively Recruiting
Overactive Bladder Syndrome
34 Actively Recruiting
Not Applicable, Phase 3, Phase 4, Phase 1, Phase 2

Fesoterodine Fumarate Reviews: What are patients saying about Fesoterodine Fumarate?

5Patient Review
5/4/2020
Fesoterodine Fumarate for Urine Leakage When there is a Strong Desire to Void
The Myrbetriq 25mg in concert with the 4mg Toviaz has been incredibly effective for me. No more leaks when coughing or squatting, and most importantly, no more dry mouth!
5Patient Review
5/4/2020
Fesoterodine Fumarate for Urine Leakage When there is a Strong Desire to Void
These two medications work great for me. I was using Toviaz 8mg before, but it made my mouth so dry that it was difficult to swallow. With these two drugs, I don't have any problems anymore.
5Patient Review
5/5/2017
Fesoterodine Fumarate for Frequent Urination
Toviaz was great until I developed dry mouth and had to urinate more frequently. I was switched to a new medication.
5Patient Review
5/5/2017
Fesoterodine Fumarate for Frequent Urination
Toviaz was working well for me until I developed dry mouth and had to urinate more frequently. My doctor put me on a new medication.
4Patient Review
2/20/2017
Fesoterodine Fumarate for Overactive Bladder
This treatment has helped me a lot. I have to be careful not to wait too long or I'll leakage, but it's still much better than what was happening before.
View All Reviews
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Patient Q&A Section about fesoterodine fumarate

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

When should I take fesoterodine?

"Extended-release fesoterodine is a tablet taken by mouth, typically once a day with or without food. It is generally taken at the same time each day."

Answered by AI

What are the side effects of the drug toviaz?

"The following text describes some of the possible side effects of a medication. If you experience any of these side effects, tell your doctor. To relieve dry mouth, suck on hard candy or ice chips, chew gum, drink water, or use a saliva substitute."

Answered by AI

What is the brand name for fesoterodine?

"Toviaz is a medication used to treat Overactive Bladder (OAB) symptoms, such as urinary incontinence, urinary urgency, and frequency."

Answered by AI

What is fesoterodine fumarate used for?

"Fesoterodine is a medication used to improve bladder function and relieve symptoms such as incontinence, urgency, and frequency in people with overactive bladder."

Answered by AI

Clinical Trials for Fesoterodine Fumarate

Have you considered Fesoterodine Fumarate clinical trials? We made a collection of clinical trials featuring Fesoterodine Fumarate, we think they might fit your search criteria.
Have you considered Fesoterodine Fumarate clinical trials? We made a collection of clinical trials featuring Fesoterodine Fumarate, we think they might fit your search criteria.
Have you considered Fesoterodine Fumarate clinical trials? We made a collection of clinical trials featuring Fesoterodine Fumarate, we think they might fit your search criteria.
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