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Nitroglycerin for Migraine
Study Summary
This trial is testing whether a new imaging tool can help show changes in blood vessels during migraine headaches.
- Migraine
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Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2019 Phase 4 trial • 66 Patients • NCT02209636Trial Design
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- You have not had any changes in your neurological exam in the past 6 months.You have had treatment or surgery on your brain for any brain issues in the past.You have a serious lung disease and need extra oxygen to help you breathe.You have not consumed coffee, tea, or alcohol for 12 hours before the angiogram.You have tried regular migraine treatments and still have severe, debilitating symptoms.You are currently taking certain medications that affect blood pressure and heart function.You have heart problems like blocked arteries or a history of heart attacks.You are taking medications similar to nitroglycerin, like phosphodiesterase inhibitors.You cannot use nitroglycerin or calcium channel blockers for medical reasons.Your angiography shows severe twisted or narrow blood vessels, blood vessel spasms that don't get better with medicine, or abnormal connections between blood vessels in your head.You have migraines that are different from other types of headaches.You have other types of headaches or pain syndromes.You are not able to accurately tell the doctor about your symptoms.You have been diagnosed with migraine by a neurologist.You have headaches at least two times every month.
- Group 1: Migraine Intervention
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
To whom does this trial open enrollment?
"This trial is aiming to recruit twenty individuals suffering from sick headaches between the age of 18 and 80. Qualified candidates must have refractory migraine symptoms, a valid diagnosis by a neurologist, not experienced any changes to their neurological exam in the last half-year, experience at least two migraines per month that can be distinguished from other types of headache pain, sign consent forms for both angiography and study participation, and agree to undergo angiography."
Is there an ongoing enrollment of participants in this clinical trial?
"Clinicaltrials.gov data reveals that the recruitment phase for this medical trial has expired since its last update on October 24th, 2022. Despite this, there are still 165 other studies actively enrolling patients at present."
Does this experiment permit participants under the age of thirty-five?
"To be included in this medical trial, the requirements state that participants must range from 18 to 80 years old. Additionally, there are separate trials for those who are under 18 (32 total) and over 65 (110 total)."
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