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Hormone Therapy

Oxytocin for Labor Complications (ROSSoL Trial)

N/A

Recruiting

Research Sponsored by Washington University School of Medicine

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Timeline

Screening 3 weeks

Treatment Varies

Follow Up during admission for delivery

Awards & highlights

ROSSoL Trial Summary

This trial is testing whether oxytocin can help during the second stage of labor.

Who is the study for?

This trial is for first-time pregnant women who are at least 37 weeks along, either going into labor on their own or being induced. It's not for those already fully dilated without oxytocin, have had children before, are expecting multiples, or whose babies have significant health issues.Check my eligibility

What is being tested?

The study randomly assigns participants to either continue using oxytocin during the second stage of labor or stop it altogether. The goal is to see how stopping or continuing oxytocin affects labor complications.See study design

What are the potential side effects?

Oxytocin may cause side effects like intense contractions leading to fetal distress, uterine rupture in rare cases, and postpartum hemorrhage due to uterine atony.

ROSSoL Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ during admission for delivery

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~during admission for delivery

This trial's timeline: 3 weeks for screening, Varies for treatment, and during admission for delivery for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Second stage duration

Secondary outcome measures

Estimated blood loss

Rate of Postpartum hemorrhage

Chorioamnionitis

+4 more

ROSSoL Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Discontinue OxytocinExperimental Treatment1 Intervention

Group II: Continue OxytocinActive Control1 Intervention

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Washington University School of MedicineLead Sponsor

1,941 Previous Clinical Trials

2,303,037 Total Patients Enrolled

University of MichiganOTHER

1,800 Previous Clinical Trials

6,378,740 Total Patients Enrolled

Media Library

Oxytocin (Hormone Therapy) Clinical Trial Eligibility Overview. Trial Name: NCT04303702 — N/A

Labor Complications Research Study Groups: Discontinue Oxytocin, Continue Oxytocin

Labor Complications Clinical Trial 2023: Oxytocin Highlights & Side Effects. Trial Name: NCT04303702 — N/A

Oxytocin (Hormone Therapy) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04303702 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What medical purposes does Oxytocin typically serve?

"Oxytocin is frequently used to address cases of hemorrhage. It can also be employed in the treatment of labor, uterine contraction, and reinforcement of childbirth."

Answered by AI

What objectives is this investigation intending to fulfill?

"This trial will monitor participants over a certain period and aim to measure Estimated Blood Loss (mL) during delivery, the occurrence of severe perineal lacerations, and any composite neonatal morbidity such as death, birth injury or hypoxia."

Answered by AI

How extensive is the participant pool for this research endeavor?

"Affirmative. Clinicaltrials.gov records demonstrate that this research project is actively seeking participants - it was first published on July 1st 2022 and updated most recently on July 11th 2022. 400 subjects require enrolment at a single medical site."

Answered by AI

Are there any remaining vacancies in this clinical experiment?

"Indeed, the details hosted on clinicaltrials.gov demonstrate that this experiment is actively enrolling participants. The trial was first published on July 1st 2022 and has since been edited for accuracy; 400 patients are needed from a single research site."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

The Role of Oxytocin in the Second Stage of Labor

Nandini Raghuraman 2022. "The Role of Oxytocin in the Second Stage of Labor". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04303702.

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