Maternal Mental Health Access for Postpartum Depression
(MaMa Trial)
Trial Summary
Will I have to stop taking my current medications?
Yes, if you are currently taking any medications for a mental health condition, you cannot participate in this trial.
What data supports the effectiveness of the treatment Maternal Mental Health Access for Postpartum Depression?
Research shows that digital mental health tools, like the Mothers and Babies Online Course, are useful and well-received for managing postpartum depression. These tools help women learn skills to manage mood changes during and after pregnancy, making them a promising option for those with limited access to traditional mental health resources.12345
Is the Maternal Mental Health Access for Postpartum Depression treatment safe for humans?
How does the Maternal Mental Health Access treatment for postpartum depression differ from other treatments?
The Maternal Mental Health Access treatment is unique because it combines digital mental health technology with remote access mindfulness-based cognitive therapy (MBCT) specifically designed for postpartum depression prevention. It offers flexible options like on-demand content and video conferencing, making it accessible for women who may have limited access to traditional mental health services.23567
What is the purpose of this trial?
This hybrid effectiveness-implementation project will allow the team to evaluate and refine implementation in preparation for future multisite trials to ultimately move the Evidence-Based Intervention (EBI) to scale among diverse populations. The plan is to enroll 120 at-risk pregnant and postpartum women from rural, urban, and Latino populations. Using a randomized preference design to also evaluate patient and sociocultural factors in participation and symptom trajectory.Using the Implementation Research Logic Model, the team will evaluate the implementation feasibility and acceptability of a remote-access and on-demand MBCT PD prevention intervention that is integrated within maternal clinical care settings using an existing patient portal. Successful achievement of the study aims will result in a refined implementation protocol for future studies that are sufficiently powered to evaluate the effectiveness of an integrated Digital Mental Health Technology and to estimate the cost/benefit ratio
Research Team
Gwen Latendresse
Principal Investigator
University of Utah
Eligibility Criteria
This trial is for pregnant or postpartum women (up to 1 year after birth) who are at least 18 years old, speak English or Spanish, and attend certain clinics. They must be at risk for postpartum depression but not have severe mental health conditions like psychosis or bipolar disorder, substance use disorders, severe anxiety, suicidality, or be on current mental health medications.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Intervention
Participants engage in an 8-week remote-access MBCT or multimedia on-demand program, with options for facilitated discussion boards or synchronous videoconference sessions
Follow-up
Participants are monitored for changes in depressive symptoms using the EPDS at multiple timepoints post-intervention
Treatment Details
Interventions
- Maternal Mental Health Access for Postpartum Depression- Prevention and UPLIFT- intervention
- On-Demand + Discussion board (DB)
- On Demand (OD) + Video Conference (VC)
Maternal Mental Health Access for Postpartum Depression- Prevention and UPLIFT- intervention is already approved in United States for the following indications:
- Prevention of postpartum depression
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Utah
Lead Sponsor
National Institute of Nursing Research (NINR)
Collaborator